Canis lupus familiaris (dog): 487515
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Entry
487515 CDS
T01007
Symbol
PLA2G4F
Name
(RefSeq) cytosolic phospholipase A2 zeta isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00564
Glycerophospholipid metabolism
cfa00565
Ether lipid metabolism
cfa00590
Arachidonic acid metabolism
cfa00591
Linoleic acid metabolism
cfa00592
alpha-Linolenic acid metabolism
cfa01100
Metabolic pathways
cfa04010
MAPK signaling pathway
cfa04014
Ras signaling pathway
cfa04072
Phospholipase D signaling pathway
cfa04217
Necroptosis
cfa04270
Vascular smooth muscle contraction
cfa04370
VEGF signaling pathway
cfa04611
Platelet activation
cfa04664
Fc epsilon RI signaling pathway
cfa04666
Fc gamma R-mediated phagocytosis
cfa04724
Glutamatergic synapse
cfa04726
Serotonergic synapse
cfa04730
Long-term depression
cfa04750
Inflammatory mediator regulation of TRP channels
cfa04912
GnRH signaling pathway
cfa04913
Ovarian steroidogenesis
cfa04921
Oxytocin signaling pathway
cfa05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
487515 (PLA2G4F)
00565 Ether lipid metabolism
487515 (PLA2G4F)
00590 Arachidonic acid metabolism
487515 (PLA2G4F)
00591 Linoleic acid metabolism
487515 (PLA2G4F)
00592 alpha-Linolenic acid metabolism
487515 (PLA2G4F)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
487515 (PLA2G4F)
04014 Ras signaling pathway
487515 (PLA2G4F)
04370 VEGF signaling pathway
487515 (PLA2G4F)
04072 Phospholipase D signaling pathway
487515 (PLA2G4F)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
487515 (PLA2G4F)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
487515 (PLA2G4F)
04664 Fc epsilon RI signaling pathway
487515 (PLA2G4F)
04666 Fc gamma R-mediated phagocytosis
487515 (PLA2G4F)
09152 Endocrine system
04912 GnRH signaling pathway
487515 (PLA2G4F)
04913 Ovarian steroidogenesis
487515 (PLA2G4F)
04921 Oxytocin signaling pathway
487515 (PLA2G4F)
09153 Circulatory system
04270 Vascular smooth muscle contraction
487515 (PLA2G4F)
09156 Nervous system
04724 Glutamatergic synapse
487515 (PLA2G4F)
04726 Serotonergic synapse
487515 (PLA2G4F)
04730 Long-term depression
487515 (PLA2G4F)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
487515 (PLA2G4F)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
487515 (PLA2G4F)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
487515 (PLA2G4F)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
487515
NCBI-ProteinID:
XP_022268713
Ensembl:
ENSCAFG00000009914
VGNC:
44629
LinkDB
All DBs
Position
30:complement(9205449..9223103)
Genome browser
AA seq
870 aa
AA seq
DB search
MHWVLWPRWLAGKGLPLLGAVLLQKREKRGPQWRQWRRETHPYFDLQVKVLRARNIQGTD
LLSKADCYVQLCLPTASSSPTRTRMIANCSDPEWNETFHYQIHGAMKNVLELTLYDKDIL
DSDQLSLLLFDLRSLKPGQPHRHTFQLKHQDSQELQVEFILENSQVPASEVITNGVLVAA
PCLRIQGTLGEGGTAPHREYGSRQIWLTVPGAYEKPQLLPLQCPKEGGLPATFTFHMNPV
ISSRLDVELEEELTVLQSGPSAELETQTSKLGQGGILLSSLTLGQEEQRSVALGEDQEVV
LNMKAEISSGDLDLRLGFGLCDGEWEFLDKRKQIVSKALQQALGLSQAPDSSQVPVVAVL
GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYKDPAWSQVSLQGPIE
RAQARVCSSKMGAMSTERLQYYVQELGSLESSGRSVSLIDLWGLLIEYFLYQEENPARLS
DQQEAISQGQNPYPIYASINVRTNINGEDFAEWCEFTPHEVGLPKYGAYVPTELFGSEFF
MGHLLQPRPEPRICYLQGMWGSAFAASVDEIFLKTAGSGLSFLDGHRWKVNITDDCQKLQ
LHDPTQLRTRLFTPQGPFSQAVLDIFTSRFTSAENFNFTRGLCLHKDYVAGQEFVAWKAT
HPDAFPNQLTPMRDRLCLVDGGFAINSPFPLNLLPQRAVDLILSFDYSLEAPFEVLQMTE
KYCLDRGIPFPRIEVLPEDLEEPRECYLFAKAEDPRSPIVLHFPLVNRTFRTHLAPGVER
QTAEEIACGDFVLNGSDTPYGMMNFTYEPEEFERLVALSRYNVLNNAETMRHALRLALEQ
QQARDRARGRPGWSRRTVREGSHRGLQTRD
NT seq
2613 nt
NT seq
+upstream
nt +downstream
nt
atgcactgggtgctctggccaaggtggctggcaggcaaggggctgcccctcctgggggca
gtgctgctgcagaagagagagaagaggggacctcagtggaggcaatggcggcgggaaacc
cacccatactttgacctccaggtgaaggtgctgagggccagaaatatccagggcacagat
ctgctgtccaaagccgattgctatgtgcaactgtgcctgcccactgcgtcctccagtccc
acccggacaaggatgatagccaactgcagtgaccccgaatggaacgagaccttccactac
cagattcatggtgctatgaaaaacgttctggagctcaccctgtatgataaggacatcctg
gatagtgaccagctctccctgttactgtttgacctgaggagcctcaagcctggccaaccc
cacagacataccttccaactcaagcaccaggattcacaagagctgcaggtggaattcatt
ctggagaacagccaagtgcctgcatctgaagtcatcaccaatggggtcctggtggctgcc
ccctgtctgagaatccagggcaccctcggggaaggtggcacagctccacatcgagagtat
ggctctaggcagatttggctgacagtgcctggggcctacgagaaaccacagctcttaccc
ctgcaatgccccaaagagggaggcctcccagccaccttcacctttcacatgaacccagtg
atcagctccaggctggatgtggagctggaggaggagcttacagtcctgcagagcggccca
agtgctgaactagagacccagaccagcaagctgggccaggggggtatcctgctatcttct
ttgaccttaggccaggaggaacagcgctccgtggccctgggggaggaccaggaggtggtt
ctgaatatgaaggcagaaataagctctggagaccttgacctgcgccttggctttggcctg
tgtgacggcgaatgggagtttctggacaagaggaagcagatcgtgtccaaggctttgcag
caagcactgggtttgagccaggctccagacagcagccaggtgcctgtggtagctgtgctg
ggttcgggaggtggaacccgagccatgtcttccctatatggcagcctggcagggctgcag
gaacttggcctcctggacactgtgacctacctgagtggggtctctggttctacctggtgc
atctccacactctacaaagacccagcctggtcccaggtgtccttgcagggccccatcgag
cgtgctcaggctcgagtctgcagcagtaagatgggggcgatgtccacagagcgcctacaa
tactatgtccaggaactggggagtctggaaagcagtggccgcagtgtttccctcatagac
ctctggggtctcctcattgaatatttcctataccaggaggaaaaccccgccagactgtct
gaccagcaagaggccatcagccagggccagaacccttaccctatctatgccagcattaat
gtccgcaccaacatcaacggggaagactttgcagagtggtgtgagttcaccccccatgag
gtcggcttgcccaagtatggtgcttatgttcccactgagctctttggctctgagttcttc
atggggcatctgctgcagccccggcctgagccccggatctgctacctgcaaggtatgtgg
ggcagtgcctttgcagccagcgtggatgagatcttcctgaagactgctggctcaggcctc
agcttcctagatgggcacagatggaaagtaaacatcacagatgactgccagaagctccag
ctacatgaccccacacagctgcgaaccaggctcttcaccccccagggccccttctcccag
gctgtgctggacatattcacctcccgctttacctctgcagagaactttaatttcaccagg
ggcctctgcctacacaaagactatgtagctggccaggagttcgtggcctggaaagctacg
caccctgacgccttccccaaccagctcactcccatgagggatcgcctgtgcctggtggat
gggggctttgccatcaactctccattccccctgaacctgctgccccagagagcagtggac
ctcattctgtcctttgactactccctggaggccccttttgaggtcttacagatgacagag
aagtactgcctggaccgaggcatccccttcccaaggattgaggtgctccctgaggacttg
gaggaaccccgtgagtgctacctgtttgccaaggccgaggacccccgctcacccattgtg
ctgcacttcccccttgtcaaccgtaccttccgcacacacctggccccaggtgtggagcga
caaacagctgaggagatagcctgtggggactttgtcctgaacgggtcagacactccctat
ggcatgatgaacttcacctatgagcctgaggagtttgagcggctggtggctctgagtaga
tacaatgttctgaacaacgcggagaccatgaggcatgccctccggctggctctggagcag
caacaggctagggacagggccagaggccgaccaggctggagtcgtaggactgtgagagag
gggagccatcgtgggctccagaccagggattga
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