Canis lupus familiaris (dog): 488422
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Entry
488422 CDS
T01007
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00230
Purine metabolism
cfa01100
Metabolic pathways
cfa04934
Cushing syndrome
cfa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
488422 (PDE11A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
488422 (PDE11A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
488422 (PDE11A)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
488422 (PDE11A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
488422 (PDE11A)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_3
HD-CE
HD
Motif
Other DBs
NCBI-GeneID:
488422
NCBI-ProteinID:
XP_038319163
Ensembl:
ENSCAFG00000013607
VGNC:
44346
UniProt:
A0A8I3PA46
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Position
36
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AA seq
920 aa
AA seq
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MTAPHLDFGEVETFLDRHPELFEDYLMRKGKQETVEKWLQRHSGGQGAVGPRPAVAGTGT
GGGAHGGGTGPNGSANSQPAPGGGDGGGVPLSPSWASGSRADGSLQRRASQKELRKSFAR
SKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPP
TAMDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAA
AGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRR
FNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCG
IAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLL
LEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSVAELVASTGLPVN
ISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNKLDGKAFDDADQRLF
EAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPPVSELA
IDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWR
HAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLY
GTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEF
FELVSKGEYDWNIKSHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERA
ELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRGQWEA
LHREGLRAAAPPPSPAAPRP
NT seq
2763 nt
NT seq
+upstream
nt +downstream
nt
atgacagccccccacctggactttggggaggtggaaactttcctggacagacacccagag
ttgttcgaagactacttgatgcggaaggggaagcaggagacggtggagaagtggctgcag
aggcacagtgggggtcagggggctgtaggcccaaggcccgcggtggccggtaccggtacc
ggcggcggggcgcacggcggtggcactggaccaaacggctctgccaacagccagcccgct
ccgggtggcggggacggtggcggggtccccctgagtcccagctgggccagtggcagccgg
gccgatggaagcctgcagcggagagcttctcagaaggagctgaggaagagttttgctcgc
tccaaggctatccacgtgaacaggacctacgatgagcaggtgacctcccgggcccaggag
cccctgagcagtgtgcggcggagggcgcttctccggaaggccagctccctgccccccacc
acggcccacattctcagtgccctgctggaatcgagggtgaatctgcctcagtacccccct
acggccatggactacaagtgccacctcaaaaagcacaatgagcgtcagttcttcctggaa
ctggtcaaagatatctccaatgaccttgaccttaccagcctgagctacaagatcctcatc
tttgtctgcctcatggtggatgctgaccgctgctctctcttcctggtggaaggggcagct
gctggcaagaagagcttggtctccaaattctttgatgtgcacgcaggaaccccactgctg
ccctgcagcagcacagagaactcaaacgaggtgcaggtcccctggggcaaaggcatcatt
ggctatgtcggggagcatggagaaacggtcaacattcccgatgcctaccaggatcgaaga
ttcaatgatgaaattgacaagctaactggatacaagacaaaatcactattgtgcatgcct
atccgaagcagtgatggtgagattattggtgtggcccaagcgataaataagattcctgaa
ggtgctccatttactgaagatgatgaaaaagttatgcagatgtatcttccattttgtgga
attgccatatctaatgctcagctctttgctgcctcaaggaaagaatatgaacgaagcagg
gctttgctagaggttgttaatgacctctttgaagaacagactgacctggagaaaattgtc
aagaaaataatgcatcgggcccaaactctgttgaaatgtgaacgctgttctgttttactc
ctcgaagacattgaatcaccagtggtgaagtttaccaaatcctttgaattgatgtcccca
aagtgcagcgctgatgctgagaacagtttcaaagaaagcatggagaaatcatcatattcc
gactggctcattaataacagtgttgccgagctagtggcttccacaggccttccagtgaac
atcagcgatgcctaccaggatcctcgctttgatgccgaggctgaccagatatcgggattt
catataagatctgttctctgtgtccctatttggaatagcaaccaccaaataattggagtg
gctcaagtgttaaataaacttgacgggaaagcttttgatgatgcagatcaacgacttttt
gaggcttttgtcatcttctgtggcctgggcatcaacaacacaattatgtatgatcaagtg
aagaagtcctgggccaagcagtccgtggctcttgacgtgctgtcataccatgcaacatgt
tcaaaagctgaagttgacaagtttaaggcagccaacatccctccggtgtcagaacttgcc
atcgatgacatacattttgacgacttctctcttgacgttgacgccatgatcacagctgcc
cttcgcatgttcatggagctggggatggtgcagaaatttaaaattgactatgagacactg
tgtaggtggcttttgacggtgaggaaaaactatcgaatggttctgtaccacaactggaga
catgccttcaacgtgtgccaactgatgtttgcaatgctaacaaccgcagggtttcaagag
attctgaccgaggtggaaattttagcggtgattgtgggatgcctgtgtcatgacctcgac
cacaggggaaccaacaatgccttccaagctaagagtggctctgctctggcccagctctac
ggaacttctgctaccttggagcatcaccattttaaccacgctgtgatgatcctgcaaagt
gagggtcacaacatctttgctaatttgtcctccaaggaatacagtgaccttatgcagctt
ttgaagcagtcaatattagcaacagacctcacgctgtactttgagaggaggactgagttc
tttgaacttgtcagcaaaggagaatatgattggaacatcaaaagccatcgtgatatattt
cgatcaatgttaatgacagcctgtgaccttggagccgtgaccaaaccgtgggagatctcc
agacaggtggccgaacttgtaaccagtgagttctttgagcaaggagatcgggagagagca
gaactcaaactcactccttcagctatttttgaccggaaccggaaagatgaactgcctcgg
ttgcaattggagtggattgatagcatctgcatgcctctgtatcaggccttggtgaaggtc
aacgcgaagctgaagcccatgctggactcggtggcggcgaaccgcggccagtgggaagcg
ctgcaccgggaggggctgcgggcggccgccccgcccccctcccccgccgccccccggccc
tga
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