Canis lupus familiaris (dog): 488593 Help Entry 488593            CDS       T01007                                  Symbol USH2A Name (RefSeq) usherin   KO K19636   usherin Organism cfa  Canis lupus familiaris (dog) Brite KEGG Orthology (KO) [BR:cfa00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:cfa03037]     488593 (USH2A) Cilium and associated proteins [BR:cfa03037]  Primary cilia and associated proteins   USH complex and associated proteins    488593 (USH2A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  fn3 Pur_ac_phosph_N EGF_laminin Ig_DSCAM-DSCAML_C Laminin_G_2 Laminin_G_1 Laminin_N Laminin_G_3 ChitinaseA_N EGF_LMN_ATRN Motif Other DBs NCBI-GeneID:  488593 NCBI-ProteinID:  XP_545710 Ensembl:  ENSCAFG00000010731 VGNC:  48174 LinkDB All DBs Position 38:complement(11100934..11787913) Genome browser AA seq 5199 aa AA seqDB search MRRPARALGPRPLTRVPEALLFASFAAISLAAPQGLFPRLENVGAFKSLTLVPPQATCGR STFCHPSAAAEGLGLCTQRLCIQDCPHRSSPPVYTALLPAGLRSCITLDKHDLCPACQSN ATSFIFGNQQDCFSSPPSPRLEASFTLAVWLKPEQEGVMCVIEKTADGQIVFKLTISEKE TIFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGLEEDNTAFDARTLS GSIIDFASGTTQIGQSLNGLEQFVGRMQDFRLYQVALTNREIQEVFSGDLLRLHIQSHCR CPGSHPRVHPSVQRYCIPNDAEDTTTDRVLRLNPEAHPLSFVNDNDIGTSWVSHVFTNIS QLHQGVTISIDLENGQYQVFYIIIQFLSPQPTAIKIQRKKEDSLDWEDWQYFARNCRAFG MENNGELENPDSVNCLQLPTFTPYSHGNVTFSILTPGPNHRPGYNDFYNTPSLQEFVKAT QIRIHFHGQYYTTETPVSLRHSYYAVDEITITGRCQCYGHADKCDTSSQPYRCLCSLESF TQGRHCDHCLPLYNDKPFQQGDQVNAFNCKPCQCNNHSRSCHYNISVDPFPFEHHRGGGG VCEDCEHNTTGRNCELCKDYFFRPVGADPSALDVCKPCDCDKVGTRNGDFLCDKIGGQCN CKRHVSGRQCNQCQNGFYNLQESDPDGCSACNCSTSGTVDGDITCHQNSGQCKCKANVIG LRCDHCNFGYKFLRSFNDDGCEPCQCNLHGSVSKLCNPLSGQCECKKEAKGLQCDTCREH FYGLDITSCKACDCDMAGSLSGTVCDAKTGQCMCKPSVGGRQCNECLEGYFYLQQNDSFL CLPCNCDKTGTVNGSLLCDKSTGQCPCKLGVTGLHCNQCVPHRYNLTSGNFQGCQMCECD SLGTLPGTICDPISGQCLCLPNRQGRRCNQCQPGFYISPGNATGCLPCSCHKMGAVHHIC NSLTGQCICQDASVAGESCDHCRDLYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFC KRFVTGSKCDTCVPRASHLDVNNPLGCSKTPSQQPPPRGQVQSSSAINLSWSPPDSPNAH WLTYGLFRDSSEIYTTEDQYPYSIQYFSDADLSPYTSYSYYIETASVHGSTRSAAVTYKT KPGVPEGNLNLSYIIPISSDSVTLAWNSPSNRSGPIEKYILSCVPFDGGQPCVPYEGHET SATIWNLAPFTKYHFSVQACTSGGCLQSSPLTVMTAQAPPRRLGPPEVRMISSTELRVEW SPPLEPNGIIIRYELYMKRLRSDGETTSAESRVFQSSGWLSPHPFVESANENALKPPQTA TTITALEPYTEYAFQVLAVNMAGSVPSTWTSERTGESVPAFMTPPSVSPLSPHSLNVSWE EPAENVTRGEVVGYKINMVSEQSPHQAIPTAVSQVLYTATSQELSYIVKELKPYRIYNFT ISLCNSIGCVTSASGAGRTLAAAPTQLRPPMVERINSTTIRVRWLAPEELNGPSPMYQLE RRESSLSAPTAIMMKGTRFTGNGYYKFPSSTHPVNTDFTGIKASFRTRVPEGLIVFAASP GNQEEYFALQLKNGRPCFLFDPQGSSMEVTTTNDGGKQYSDGKWHEIIAIRHQAFGQITL DGQYTGSSATQNGSTIIGGNTGVFVGGLPQGYTILRKDPDIIQKGFVGCVKDMYFMKKYN PFAIWEPLVWQSAEEQVNVYNSWEGCPTSLQDGAQFLGTGFLELHPYIFHGGMDFEISFK FRTDQLNGLLLFIYNKDGPDFLAIELKSGILSFRFNTSLTFTQVDLRLGMSYCDGKWNKV IIKKKDSLIAASMNELRECVSQSRAQPLMVNSPVYVGGTPQELQDSYKHLSLEQGFGGCM KDVKFARGAVVNLASVSSSAVRVNLDGCLSTDSDVNCRGNDSILVYQGKEQSVYESGLQP FTEYLYRVVASHEGGSVYSDWSRGRTPGAAPQSVPTPSRVRSVNGYSIEVTWDEPVVVRG VIEKYVLRAYSEDDPHSPRRPSATSELFNTSTLTGILTGLLPFKNYAVTLTACTLAGCTE SSHALNISTPQEAPQEVQPPTAKSLPNSLVLSWNPPKKANGVITQYSLYMDGMLIYSGSG ENYTVTDLAVFTPHQFLLSACTHVGCTNSSLVILYTAQLPPEHVDSPLLTVLDSRTIYVQ WKQPRNVNGILERYILYISNHTRDFTIWDVIYNSTELFQDHQLRHLSPGNKYLIKLGACT GGGCTVSEASEALTDEGAPEGVPTPKAHSSSPHSFNISWTEPEYPNGVITSYGLYLDGIL IHNSSELSYHAYGFAPWSLHSFRVRACTAKGCALGPLVENRTLEAPPEGTVNVFVKTEGS RKAHVRWEAPSHPNGHLTYSVLFTGLFYADQADNNYTLLNGTQVMHSGEETNLWVLIEGL VPFTDYTVQVNVSNSQGSLISDPITFAMPPGAPDGVLPPRLSSATPTSLQVVWSTPARNN APGSPRYQLQMRPGHSTHGFLELFSSPSASLSYEVRDLQPYTEYEFRLVASNGFGSAPSS WILFVTTEDKPGPVDPPILLDVKSRMMLVTWQHPLKCNGVITHYSIYQHGHLSLKTSGNV TNCTVIHLRPYTPYKFQVEACTSKGCSLSPESQTVWTLPDAPEDIPSPELFSDTPTSVII SWQPPTHPNGLVENFTIDRRVQGEEEVTTLVTLPRSHSMRFIDKTPALSPWTKYEYRVLM STLNGGTNSSAWAEVTTRPSRPAGVQPPVVHVLGPHTAEVTWKPPLIQNGDMLSYEIRMP DPHITITEVTSSGLSRVITHLIPFTNYSVTIVACSGGNGYLGGCTESLPTQVTTHPTLPQ GINPLLVIPLSESYVGISWQPPSRPNGPDLRYELLRRKIQQPLASNPPEDLNLWHNIYSG TQWFYEDKGLSRFTTYEYQVFVHNSVGFTPSQGATVTTLAGLPERGANLTATVLNHTAIH VTWAKPTFQDLQGDVEYYTLFWSSATSNESLKILPDVNSHVISHLNPNTEYRIFLSVFNG VHSISGEVLHATTFDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSVYVNNKLY KTGMNVPGSFILRDLSPFTIYDIQVEVCTKYACVKSNGTQFTTVEDTPSDIPTPTIHGIT SRSLQVDWMSPGKPNGIILGYDLLRKKHSCPKIQKLRKDHSGVLCKAVKCQKPKSVCGHR CYSPEAKVCCNGVLYDLQPGHHCCEEKYIPFILNSTVVCCGGRIREAQPNHRCCSGYYAR MLPGEVCCPDEQHNRVSTGIGDSCCGRLPYSTSGNQICCAGRLHDGYGQQCCGGQIVSKD LECCGGEEEGMPYSRLPGMFCCGQDYVNMSDTICCSASSGESKAHVKKNDPVPVKCCETE LIPKSQKCCNGVGYNPLKYVCSDKISTGMMMKETRECGTLCPASLEATAYCGRCDFNFTS HICTMIRGPHISTGKESAEEICSYAEETVHTGSVNTFSFTDVNLEPYMTYEYRISAWNRY GRGFSKAIRARTKEDVPEGVSPPRWTKMDNLEDVIILNWKKPIQSNGPIIYYILLRNGIE CFQGTSLSFSDSKGIEPFQEYSYQLKACTVAGCAVSSKVVAATTQGVPESVLPPRVRAPS AEALHLSWSIPEKPNGIIKEYQLRQTGRGLIYSGTSDRRQHTVTGLQPYTNYSFTLTACT SAGCTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVELYWNPPEKPNGLISQYQLSRNGT LVFLGGSEEQNFTDKNLEPNSRYIYKLEATSGGGSSPSDDYIVQTPMLTPEEIQPPYNIT VIGPYSIFVAWTPPGILIPKMPVEYNVLLNAGSVAPLTSSVGHHQSILLENLAPFTQYEI RIQACQNGSCGVSSRTFVKTSEAAPVDLNSPVLKALGSACIEVKWMPPKKPNGVITSYFL HRRPAGIEEESLLFVWSEGALEFTDASDTLMPFTLYEYRVRAHNSRGSVESQWSSARTLE APPQDLPAPWVQATSAHSVLLNWTKPESPNGIISQYHVVYRERPDDSTVNISTVHAFTVM GTSHQAHLFGLEPFTTYHIGIVATNQAGEVSSPWTVVQTLESSPSGLGNFTVEQQENGRA LLLQWSEPVRTNGVIKTYHVFSDGSLEYSGPTRRFLFRRLLPFTAYALHLEACTGAGCAC SGAQRLRTGEAPPRSQAPPTVQWAGPGGVGLRWAAPLHPRGRIVRYEVVRRCLDGPARGN QTLRADGAAVFTEYDTERSAFTYNDTGLQPWTRCEYRIRTWNSAGHTCSSWAAARTTQAP PEGLSPPGIAGVSVSPPRLLISWTPPERPNGIIQSYRLRRNGALYPFSFDAVTFNYTDED LLPFSTYSYAVVACSSGGCSTSKPSSTTTPQAAPAGLSPPAPRAISATQINVSWSPPLIH NGNITKYLLRVDGKEYLAGQSLSLLVSGLQPSTRYNFSLVACTDGGCTASASKPAWTTEA PPQNMDPPKLQVTGSESIEITWRPPRNPNGQITSYELRRDGTIVYTGLETRYHDFTLTPG VEYGYTVTAHNSQGGVLSPLVKDRTDPSAPSGIEPPKLKAQGPQEILVNWDAPVRTNGQI VNYSLFIRELFEEETKILPINTTHNSFDTRSFVVDQLKPFHRYEVRIQACTALGCASSDW TSLQTPEVAPLMQPPPHLEVRMAPGGFQPVVALLWTGPLQPNGKVIYYELYRRQIAAHPG KSNPVLTYNGSSSSFTDFELSPFTEYEYQVWAVNSAGKAPSTWAWCRTGPAPPEGLGAPK FHAVSSTHAVVNISAPEKPNGIINIYRLFSNTSGVETVLSEGTATQQTLHGLQPFTTYSI GVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIQMLSSRTASFQWSPPLLPNGVIQSYE LQLHVACPPDLAAPCAPSQAETKYSGLGQTASLEGLQPYTTYKLRVLAHNEVGSTASEWI SFTTQRELPQYRAPFLVDSNLSLVRVDWSGSFLLNGPLKEFVVMDGGQRVYSGFDTTLYI PRTADKTFFFQIICTTDEGSVKTPVVQYDTSTGFGLVLTTPGEKRGSGSKSTEFYNELWF IVLMAVLGLILLAIFLSLLLQRKIHKEPYIRERPPLVPIQKRMSPLNVYPPGETHVGLAD TKIPHSGTPVSIRSNRSISVLRIPSQSQISQTYSQGSLHCSVSQLMDLQDKKVLVDDSLW ETIMGHDSGLYVDEEDLMNAIKGFSSVTKEHTTFTDTHL NT seq 15600 nt NT seq  +upstreamnt  +downstreamnt atgcggcgcccggctcgggccctgggcccccgccccctgacccgcgtccccgaagctctg ctcttcgcgtctttcgctgccatctccctggccgcccctcagggtctcttccccaggctg gagaacgtgggcgctttcaagagcctgacccttgtgcccccccaagcgacctgtgggcga agcacgttttgtcacccctctgccgccgccgagggcctcgggctctgcacccagcgcctc tgcatccaggattgcccccacagatcctcccctcccgtctacaccgccctgctccccgcg ggcctgcgcagctgcatcaccctggacaagcacgacctgtgtcccgcctgccagagcaac gccaccagtttcatctttggaaatcagcaggattgcttttcctctcctccttctccaagg ctggaggcatcctttaccttagccgtgtggctgaaacccgagcaagaaggtgtaatgtgt gttatagaaaagacggcggatgggcagattgtgttcaaacttacaatatccgagaaagag accatattttattatcgcacagtaaatggtttgcagcctccaataaaagtaatgacactg gggagaattcttgtgaagaaatggattcatcttagtgtgcaggtgcatcagacaaaaatc agtttcttcatcaatggtttggaggaagataatacagcatttgatgcaagaactctaagt ggttcaataatagattttgcctctggtactacacaaataggacagagtttaaatggatta gagcagtttgttggaagaatgcaagattttcgattatatcaagtggcgctcacaaacagg gaaattcaggaagttttctctggagatctgctcagactgcatattcagtcacattgccgc tgccctggaagccaccctagggtccatccttcggtacagcggtactgcattcctaatgat gcagaagacacaaccactgatagggtgttacggctgaatcctgaagcccatcctctttct tttgtcaatgataatgatattggtacttcatgggtttcacatgtgtttacaaacattagc cagcttcatcaaggagtgactatttcaatagatttggaaaatggacaatatcaggtgttt tatattatcattcagttccttagtccacaaccaacagcaataaagattcaacggaagaag gaggacagcctagattgggaggactggcaatattttgctagaaattgcagagcttttgga atggaaaataatggagaattggaaaatcccgattctgtcaactgtcttcagcttcccact tttactccatattcccatggtaatgtcacatttagcatcctaacacctggaccaaatcat cgtcctggctacaacgacttttataataccccatctcttcaagagtttgtaaaagccaca caaataagaattcattttcatggacagtactatacaactgagactcctgtcagcctcagg cacagttactatgcagttgacgaaatcaccatcacggggagatgtcagtgctatggtcat gctgataagtgtgacacaagcagccagccctatcgatgcctctgctctctggaaagcttc acccagggacgtcactgtgatcattgcttgcctctttataatgataagcctttccaacaa ggtgaccaagttaatgccttcaattgtaaaccctgtcaatgcaacaaccattccaggagc tgccattacaacatctcagtggacccatttccatttgagcaccacagaggaggtggaggg gtctgtgaggattgtgagcataacacaacagggaggaactgtgagctgtgtaaggattac tttttccggccagttggtgcagatccttccgccctggatgtttgcaaaccctgtgattgt gataaagtgggcactaggaacggtgacttcctctgtgataagattggaggccagtgtaat tgtaagagacatgtgtctggcagacagtgcaatcagtgccaaaatggattctacaatcta caagagtcggatcctgatggctgcagtgcctgtaactgcagtacctctgggacagtggat ggagatattacctgtcaccaaaattcaggccagtgcaagtgcaaagcaaatgttattggg cttagatgtgatcattgcaattttggatataaatttctccgaagttttaatgatgacgga tgtgagccctgccagtgcaacctccatggctcagtgagcaaactctgcaatccgctttct gggcagtgtgagtgcaagaaagaagccaaaggacttcagtgtgacacgtgcagagaacac ttctacgggttggacatcaccagttgtaaggcctgtgactgtgacatggctggatctctc tctgggaccgtctgtgacgccaagacagggcagtgcatgtgcaagcccagtgttggaggg agacagtgcaatgaatgtttggagggctacttctacctccagcaaaatgattctttcctc tgtctgccttgtaactgtgataagactgggacagtaaatggctctctgctgtgtgacaaa tcaacaggacaatgtccttgcaaattaggagtaacaggtcttcactgtaatcagtgtgtg cctcacaggtacaatttgaccagtggcaattttcaaggctgccagatgtgtgagtgtgac tccttggggacattaccgggcaccatttgtgacccaatcagtggccagtgcctgtgttta cctaatcggcaaggaagaaggtgtaatcagtgtcaaccaggtttttatatttctccaggc aatgccactggctgcctgccatgttcatgccacaaaatgggtgcagttcatcacatctgt aatagcctaactggtcagtgcatttgccaagatgcttctgttgctggggaaagttgtgac cattgtagagacctttactttggatttgatcctcagactggaagatgtcagccttgcaat tgtcatctctcaggagccttgaatgaaacctgtcacttggtcacaggccagtgtttctgt aaacgatttgtcactggctccaagtgtgatacttgtgttcccagggcaagccatttggat gtgaacaatccactgggctgcagcaaaactccgtcccaacaacctccacctagaggacaa gttcaaagttcttctgctatcaatctctcctggagtccacctgattctccaaatgcccat tggcttacttatggtttattcagggatagttctgaaatctacacaactgaagatcaatac ccatacagtattcagtacttctcggatgctgacctgtcaccatatacttcatattcctat tacatcgagactgccagtgtgcatggttcaacaaggagtgcagctgtcacttacaagacg aaaccaggggtcccagaaggaaacctgaacttgagttatatcattcctattagctcagac tccgtgacacttgcttggaattcaccttcaaatcgttctggtcctatagaaaaatatatt ttgtcctgtgttccttttgatggtggccagccatgtgttccttatgaaggtcatgagact tctgctaccatctggaatctggctccattcaccaagtaccatttttctgtacaggcatgt acgagtgggggctgtttacaaagctcaccccttacagtgatgacagcccaggcacctccc cgaaggctgggtccacctgaggtgcggatgatcagttccacagaacttcgtgtagaatgg tctcccccactggagccaaatggaataattataagatatgaactctacatgaaaagattg agatctgatggagaaaccacctcagcagaaagtcgagtctttcagagcagtggctggctc agtcctcacccatttgtagaatcagccaatgaaaatgcattgaaacctcctcaaacagcc acaaccatcactgccttggagccatacactgagtatgcgtttcaagtcttagctgtgaac atggctggcagcgtgccttctacctggacttcggaaagaacaggagaatcagtgccggca ttcatgacccccccttccgtctccccactctcaccacactccctcaatgtgtcctgggag gagcccgcggagaatgtaacaagaggagaagttgtggggtataaaatcaatatggtttct gaacagtcacctcaccaagctattccgacagcggtgtcacaggtgttgtacactgctaca tcccaagaactgtcttatattgtaaaagaactgaaaccttataggatatacaactttact atttctctctgcaattcaattggttgtgtaaccagcgcatcaggagcaggacggacatta gcagcagcgccaacccaactgaggcctcccatggtggaaagaatcaacagcacaaccatc cgtgttagatggctcgcaccggaagaactcaatggaccctctcccatgtatcagctggag aggagagagtcatctctctcagctcccacagccataatgatgaaaggaactcgtttcaca ggaaatggatattataaatttcccagctccacacacccagtcaatacggactttactggc attaaggccagctttcgaacaagggtgcctgaaggtttgattgtctttgcggcatcgcct ggcaatcaggaagagtattttgcacttcagttgaagaatggacgtccttgttttcttttt gatcctcaggggtcttcaatggaagtaactacaaccaatgatggtgggaaacaatacagt gatggcaaatggcatgaaataatagctattaggcatcaggcttttggccaaatcacactt gatgggcagtacacaggttcttcggccacccagaatggaagcactatcattggagggaac acgggagtgtttgtgggaggacttccacagggttacaccatcctcaggaaggatcccgac ataatccaaaagggttttgtgggctgtgtcaaggatatgtattttatgaagaagtataat ccctttgctatttgggagcctctggtttggcagagcgctgaagagcaagtcaacgtgtat aacagctgggagggatgccccacttcattacaagatggagcccagttcctgggaacaggg ttcctggaactccatccatacatatttcatggcggaatggattttgagatttccttcaag ttcagaactgaccaattgaatggattgcttcttttcatttacaacaaagatggacctgat tttcttgctatagagctgaagagtggaatattgagcttccggttcaataccagtcttacc tttacacaagtggatctacggctcgggatgtcttattgtgatggaaagtggaataaagtg attattaaaaagaaagattccctcatagcagcaagcatgaatgaactgagggaatgtgtg tcacagtccagagcacagccactgatggtgaattccccagtctacgtgggaggaacccca caggagctgcaggactcttataaacacctgagtttggaacaaggtttcggtggttgcatg aaggatgttaaatttgcacggggtgctgtcgttaacttggcatctgtgtccagcagtgct gtcagagtcaatctggatggatgcctatcaactgacagcgatgttaactgcaggggaaat gactccatcctggtttaccagggaaaagagcagagtgtttacgagagtggtctccagcct tttacagaatacctgtatcgagtggtagcctcacacgaaggaggttctgtatacagcgat tggagtcggggccgcacaccaggagcagctccacaaagtgtgccaactccctcaagagtc cgcagcgtaaacggatatagcattgaggtgacctgggacgaacccgttgtggtgagagga gtaattgagaagtacgttctgcgagcctacagtgaggatgacccccattcaccccgtagg ccctcagccacgtctgagcttttcaataccagcaccctcacaggcatattgacaggcttg ctacccttcaaaaactatgcagtaaccctaactgcttgcactttggctggctgtactgag agctcacatgcattgaacatctctactccacaagaagccccgcaggaagttcagccacca acagccaaatctcttcccaattctttggtactgtcctggaatccacctaaaaaagcaaat ggtgttataactcagtactctttatatatggatgggatgctaatctattcaggcagtgga gaaaactacacagtcacagatttagcagtatttacaccccaccagttcctgctcagtgcc tgcacgcacgtgggatgtacaaacagttccctggtcatcctgtacaccgcacagctgcca ccagaacacgtggactccccacttctgactgtcctggattctagaactatatatgtacag tggaaacaaccaagaaatgtaaatgggattctggagcgctatatactatatatttcaaat cacacgcgtgattttacaatttgggatgtcatctataacagtacagaactttttcaggat caccagctacgacacttgtcccctggcaacaaatatctcatcaagctgggagcttgtaca gggggcgggtgcacagtgagcgaggccagtgaggccctgactgatgagggggcacccgaa ggtgtgccaactcccaaagcgcactcctcttcacctcactcctttaacatctcctggact gagcctgaatatccaaatggtgttatcacaagctatggactatatctagatggtatatta attcacaattcctcagaactcagctatcatgcttatggatttgctccttggagcttacat tccttcagggtccgagcatgcacggccaaaggttgtgccctgggcccgctggtggaaaat cgaactctagaagctcctcctgaaggaacagtaaacgtgtttgtcaaaacagaaggatcc cggaaagcccacgtgaggtgggaagcaccttctcaccctaatggacacttaacatactca gtcctttttactgggcttttctatgccgatcaagcagacaataactacactcttctgaat ggcacacaagtcatgcacagtggtgaagagaccaacctttgggtactcatcgaggggctg gttccttttactgattataccgtacaagtgaatgtttcaaatagccaaggcagcttgata agtgatcctataacatttgcaatgccgcctggggctccagatggcgtgctgcctccgagg ctttcatctgccactccaaccagtcttcaggttgtctggtctacaccagctcgtaacaac gctcccggctctcccagataccagctccagatgaggcctggccactccacccatggattt ctagagttattttccagtccttctgcatcgttaagctatgaagtgagagatctccaaccg tacacagaatatgagtttcggttggttgcctccaatggatttggcagtgcacctagttct tggattctattcgtgaccacagaggacaaacctggacctgtggaccctccaattcttctg gatgtgaagtcaagaatgatgttggtcacctggcagcatcctttaaagtgcaatggggtc attacccactatagcatttaccaacatggccacctctccctgaaaacttctggaaatgtc actaattgcacagtgatccatttacgcccatatactccctataagtttcaggtagaagcc tgtacttccaaagggtgttccctctccccagagtcccagaccgtgtggacactcccagat gcaccagaagatatcccaagtccagagctattctctgataccccaacatctgtgattata tcttggcaacctcccactcaccccaatggcttggtggagaacttcacaattgacagaaga gtccaaggcgaggaagaagttactaccctggtgactctcccaagaagccattccatgagg tttattgacaagactcctgcccttagcccatggacaaaatatgaataccgggtactaatg agcactctcaacggaggtacaaacagcagtgcttgggcggaagtgaccacgagaccctca cgacctgctggggtgcagccacctgtggtgcatgtgctaggaccccacacagccgaggtc acttggaaaccccccctcatccagaatggtgacatgcttagctatgagatccgcatgccg gatcctcacatcaccataaccgaggttacttcctcagggttaagtcgagtaattactcat ctgattcctttcactaattactctgtcaccattgtggcttgctcaggaggtaacgggtac ctaggaggatgcacagagagcttacctacccaggtcaccacccaccccaccctacctcag ggcattaacccgttgttggtgattcctctaagtgaatcatatgttgggatttcgtggcag ccaccatccagaccaaatggacccgatttgagatatgagcttctgagacgtaaaatccag caaccacttgcatcaaatcccccagaagatttaaatctgtggcacaatatttattcagga actcagtggttttatgaagataagggtcttagcaggtttacgacgtatgagtatcaagtc tttgtacacaacagcgtgggtttcacaccgagccaaggagctaccgtgacaacattagct ggtcttccagagaggggagccaatctcactgcaactgttcttaaccatacggccatccat gtgacatgggctaaaccaacctttcaagacctacaaggtgatgttgaatattatacactt ttttggagttctgctacctcaaatgaatctctcaaaatcctcccagatgtaaactctcat gtcatcagccacttaaatccaaacacagagtatcggatttttctctctgtcttcaatgga gtccacagcatcagtggcgaagtactgcacgcaaccactttcgatggggagcctcagggc atgcttcctccagaggttgtcatcatcaacagtacagctgtacgtgtcatctggacatct ccttcaaacccaaatggtgttgtcactgaatattctgtctatgtaaataataagctctac aagactggaatgaatgtgcctgggtctttcattctgagagacctgtctcccttcactatc tatgacattcaggttgaagtctgcaccaaatatgcctgtgtgaaaagtaatggaacccaa ttcaccactgtggaagataccccgagtgatataccaacacctacaattcatggcatcact tcaagatcccttcaagttgattggatgtctccagggaagccaaatggcatcattcttgga tatgatctcttacgtaaaaagcattcatgccctaaaatccagaagttaaggaaggaccac agtggtgtgctctgcaaggcagtaaagtgtcaaaaacctaaaagtgtctgtggacacagg tgctattctcctgaagctaaggtttgttgtaatggagttctctacgacctccagcctgga caccactgctgtgaagagaagtatatcccattcattttgaattccactgtggtttgttgt ggtggccgaatacgagaggctcaaccaaatcatcgctgctgctctgggtattacgctaga atgctaccaggtgaagtatgttgtccagatgaacagcacaatcgggtttccactggcatc ggtgactcctgctgtggcagattgccttactccacctcaggaaaccagatttgctgtgct gggaggcttcatgatggctatggccagcagtgctgtggtggacagattgtgagcaaagat ttagaatgctgtggtggagaagaagagggcatgccatacagtcgccttccagggatgttc tgttgtgggcaggattatgtgaatatgtcagataccatatgctgctcagcttccagtgga gagtctaaagcacatgttaaaaagaatgacccagtgccagtaaaatgctgtgagactgaa cttattccaaagagccagaaatgctgtaatggagttggatataatcctttgaaatatgtt tgctctgacaagatttcaactggaatgatgatgaaggaaaccagagagtgcgggactctc tgcccagcatctctggaagccacggcatattgcggcaggtgtgacttcaactttaccagc cacatttgcactatgatcagaggacctcacatttctacaggcaaggaatcagcagaagaa atatgctcatatgctgaagagactgttcacacgggaagtgtaaacacattctccttcaca gatgtgaacctggagccttatatgacatatgagtataggatttctgcatggaatcgctat gggcgaggattcagcaaagccattagagccaggacaaaagaagatgtgcctgaaggagtg agtccccctagatggaccaaaatggataatcttgaagatgtgataatcttaaattggaag aaacctatacaatcaaatggtcctattatttactacattcttctccgaaatgggattgaa tgctttcagggaacatcactgagcttctctgattcaaagggaattgaaccatttcaggaa tactcataccagctaaaagcttgcacggttgctggctgtgccgtcagcagcaaggtagtt gcagctactacccagggagtcccggagagcgtcctgccgcccagggtcagggcacccagc gcggaggccctgcatttgagctggagcatccctgagaaaccaaatggcatcattaaagag taccagctcaggcagactgggagaggtctcatctacagtggcaccagtgacaggaggcag catacggtcacaggtctccagccatacaccaactacagcttcacacttacagcttgtaca tctgctggatgcacttcaagtgagccttttctaggtcagacactgcaggcagcccctgaa ggagtttgggtgacacctcgacacattatcatcaattctacaacagtggaattatattgg aatccgccagaaaagcccaatggcctcatttctcagtatcaattgagtcgtaatggaacc ttggttttcctgggtggcagtgaggagcagaatttcactgataaaaacctggagcccaat agcagatacatttataaattggaagctacaagtggaggtggcagcagtcctagtgatgat tacattgtacaaacacctatgctgacaccagaagaaatccagcctccatataatatcaca gtaattggaccttattccatatttgtagcttggaccccaccagggatcctcatccccaaa atgcctgtggagtacaatgtcttactcaatgctggaagtgtagcgcctctgacctcctct gttggtcatcatcaatccatccttctggaaaatttggctccattcacacaatatgagata aggatacaagcatgtcaaaatggaagttgtggcgttagcagtagaacgtttgtcaaaaca tctgaagcagccccagtggatctcaattccccggttcttaaggccctggggtcagcttgc atagaggttaaatggatgccgcctaaaaagccaaatggagtcatcaccagctactttctt cacagacgtcctgctggcattgaagaggagtcccttttgtttgtctggtcggaaggagcc cttgaattcacagatgcctcagatactctgatgccgttcacgctctatgaataccgggtg agagcccacaactccagaggctcagtggagagtcagtggtcatcagcaaggaccctggaa gccccacctcaagatttgccagcaccttgggtgcaagccaccagtgctcattcagttctg ctgaactggacaaagccagaatctcccaatggcattatctcccagtaccacgtggtctac cgagagagaccagatgattcaacagttaacatctctactgtgcacgctttcaccgtgatg ggaacaagtcatcaagcccacctgtttgggttagaaccattcacaacatatcacattgga attgtggccacaaaccaggcaggagaagtttcaagcccctggactgtggttcaaaccctg gaatcttccccaagtggactgggcaactttacagtagaacagcaggagaacggccgggca ttgttgctacagtggtcagagcctgtgagaaccaatggtgtgattaagacgtaccacgtc ttcagcgacgggagcctggagtacagcggcccgactcgccgcttcctcttccgccgcctg ctccccttcaccgcctacgcgctgcacctggaggcctgcaccggggccggctgcgcatgc tccggcgcccagcgcctgcgcacgggggaagccccgccccgctcgcaggccccgcccacc gtgcagtgggcggggcccggcggcgtcgggctgcgctgggccgcgcccctgcacccgcgc gggaggatcgtccgctacgaggtggtccgcaggtgcttggacggaccagcccgggggaac cagacgctgcgggccgacggggcggccgtcttcacggaatacgatacagaaaggagcgca tttacgtacaatgacacaggtttgcagccctggacgcgctgcgagtatcggatccgcacc tggaactcggcaggccacacctgcagctcctgggccgcggcaaggacgacgcaggcgcct ccggagggtctctcccccccggggatagccggtgtttctgtgagtccccccagactgctc atctcctggaccccgcccgagcggcctaacggcatcatccagtcgtacagacttcggagg aacggggcgctctaccctttcagctttgatgctgtgaccttcaattataccgatgaagac ctgcttccgttttccacgtacagctacgcggtcgtagcctgctcgagcggaggctgctcc accagcaaacccagcagcaccaccaccccccaggcggcgccggcaggactcagccctccg gccccgcgggccatcagcgctactcagataaacgtgtcgtggtccccgccgctgattcac aatggaaacatcactaaatacttgcttagggttgacggtaaggagtacctcgctgggcag agcctgtccctgctggtttctggcctgcagccttccacccggtataatttctccctggta gcctgcacagacggagggtgcacggccagtgcatcgaaacctgcctggacgacggaggcc ccgccgcagaacatggaccccccaaaactgcaagtcacaggctcagaatcgatagaaatc acctggagacctcccaggaacccaaacggccagatcacgagttatgaacttaggcgggat ggaaccattgtctatactggcctggaaacgcgctatcatgacttcactctgaccccaggt gtggaatatggctacacagtgactgcccacaatagccaagggggtgttttgagtccgctc gtcaaagacaggaccgacccctcggcgccctcagggatagaacctccaaaattgaaggcc cagggcccgcaagagattttagtgaactgggacgctccagtgaggacaaatggccagatt gtcaattactccctctttatccgagagctgtttgaagaagaaacaaaaatcctacccatc aacacaactcacaattcttttgacacgcggtcattcgtcgtagaccagctgaagccattt cacaggtacgaagtacgtattcaagcctgcaccgcactgggatgtgcatcaagtgattgg acatccctacagacccctgaggtggcgcctctgatgcagcccccaccacatctagaggta cggatggctccagggggattccagcccgtggttgcccttttgtggactggaccacttcag ccaaatggaaaagttatatattatgagttgtacagaagacaaatagcagctcatcctgga aaatcaaatccagtgctaacctataatggaagctcgagctcttttacggatttcgaacta tcacctttcacagaatatgagtatcaggtttgggcagtgaattcagcaggaaaagccccc agtacttgggcatggtgtagaactgggcccgcccccccagaaggtctcggagcacccaag ttccatgcagtctcttccacccatgcagtggtcaacatcagcgcccctgagaagcccaat ggaataatcaatatttacaggttgttctccaacaccagcggggtggagacagtgctgtct gaaggcacggctacccagcagactcttcacggcctacagcccttcaccacgtactccatt ggggtggaagcctgcacttgcttcaattgttgcagcaaagggccaacggcagagctgaga actcatccagctccaccctcgggactgtcctctccccaaatccagatgctgtcctcaagg acagcttccttccagtggagcccacccctgttgcccaatggtgtcattcaaagctatgag cttcaactccacgtggcttgccctcccgatttagcagctccatgtgctcccagccaagca gagacaaagtactcggggctggggcagacagccagcctagagggcctccagccctacacc acctacaaactgagagtgctggcccacaacgaggtgggcagcacggcctctgaatggatc agcttcaccacccaaagagaattgccccaataccgagccccattcttggtggacagcaat ttgtctctggtgcgtgtagactggagtggctctttccttctgaacggcccgctgaaggag tttgtggtgatggatggaggccagcgtgtgtacagtggcttcgacaccaccctctacata cccaggacggcagacaaaaccttctttttccagatcatctgcaccacagatgaaggaagc gttaagacacccgtggtccaatatgatacctctacgggatttggcctggttctgacaact cctggagaaaagagaggctcggggagcaaaagcaccgagttctacaacgagttatggttc atcgtgttaatggccgtgctaggcctgatcttgttggccatttttctgtctctgctactc caaaggaaaatccacaaggaaccgtatatcagagagaggcctcccttggtgcctattcag aagagaatgtctccgctgaatgtctatccgccgggggaaacccatgtgggattagccgat accaaaatcccccactctgggacacccgtcagtattaggagcaaccggagcatatccgta cttcggatcccaagtcagagccaaataagccaaacctattcccaaggctctctccactgc agtgtcagccaactcatggaccttcaagacaagaaagtcttggttgatgactcgctgtgg gaaaccatcatgggccacgatagtggactgtacgtggatgaagaggacctgatgaatgcc atcaagggtttcagctctgtgactaaggagcacaccacgttcaccgacacccacctgtga

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