Canis lupus familiaris (dog): 489030 Help Entry 489030            CDS       T01007                                  Symbol PRF1 Name (RefSeq) perforin-1 precursor   KO K07818   perforin 1 Organism cfa  Canis lupus familiaris (dog) Pathway cfa04210   Apoptosis cfa04650   Natural killer cell mediated cytotoxicity cfa04940   Type I diabetes mellitus cfa05320   Autoimmune thyroid disease cfa05330   Allograft rejection cfa05332   Graft-versus-host disease cfa05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:cfa00001]  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     489030 (PRF1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     489030 (PRF1)  09160 Human Diseases   09163 Immune disease    05320 Autoimmune thyroid disease     489030 (PRF1)    05330 Allograft rejection     489030 (PRF1)    05332 Graft-versus-host disease     489030 (PRF1)   09166 Cardiovascular disease    05416 Viral myocarditis     489030 (PRF1)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     489030 (PRF1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF C2 Motif Other DBs NCBI-GeneID:  489030 NCBI-ProteinID:  NP_001184111 Ensembl:  ENSCAFG00000014071 VGNC:  44964 UniProt:  C5IY80 LinkDB All DBs Position 4:complement(21630717..21633264) Genome browser AA seq 555 aa AA seqDB search MGARLFLPGLVLLLLPTPTPAPCHTATRNECRRNRWFVPGSMLAGEGMDVTSLKRSGSFP VDTESFLRPDGTCTLCRNTLRGGALQRLPLALTDWRAQGSGCQRRVVKAKASSTEGVARE AASNIHNDWRVGLDVSPKPNINVHVSMAGSHSRVADFAAQKTHQDRYSFSTDVVECRFYS FHLVHSPPLHPNFQRALSDLPPNFNTSTEADYLRLISNYGTHFIRSMELGGRTLALTALR TCELALEGLTADEVSDCLTVEAQVSISDHANPSSEFKACEEKKKKHKMTTSFHQAYQERF SEIIGGHHTSMSDLLFGNQAGPEQFSAWMASLLDRPGLVDYTLEPLHVLLESQDPRREAL RQAVSKYVMDRARWKNCSRPCPPGQQKSPHNPCHCVCHNSGITNQDCCPRQRGLAHLEVM NFQAMGLWGDYFTATDAYLKVFFGGQEQRTYTVWNNNNPTWVTRLDFGNVLLSTGGPLRV QVWDQDYGWDDDLLGTCDQKAQSGSHEVRCNLSHGHLRFSYIAKCLPHLTGATCLEYAPH GRLGEPPGNRSGPVW NT seq 1668 nt NT seq  +upstreamnt  +downstreamnt atgggtgcccgcctgttcctcccgggcctcgtcctgctgctgctgcccacgcccacccca gccccctgccacacggccacgcgcaacgagtgccggcgcaaccgctggttcgtgcctggc tcgatgctggccggggagggcatggacgtgaccagcctcaagcgctcgggctccttccca gtcgacacagagagcttcctgcggcccgacggcacctgcaccctctgccgcaacacccta cgggggggtgccctccagcgcctgcccctggcactgaccgactggcgcgcccagggctcg ggctgccagcgccgcgtggtcaaggccaaggccagctccaccgagggtgtggccagggaa gcagccagcaacatccacaacgactggcgcgtggggctggatgtgtctcccaagcccaac atcaatgtgcatgtgagcatggccggctcgcactccagggtggccgacttcgctgcccag aagacccaccaggacaggtacagcttcagcactgacgtggtggagtgtcgcttctacagt ttccacctggtacactctccgccactgcaccccaatttccagagggccctcagcgacctg ccccccaatttcaacacctccacagaggctgactacctcaggctcatctccaactatggc acccacttcatccggtccatggagctgggcggccggaccctggccctcactgccctgcgt acgtgtgagctggccctggaagggctcacagccgatgaggtgtcagactgcctaacagtc gaggcccaggtcagcataagtgaccacgccaacccttcatcagaattcaaggcctgtgag gaaaagaagaagaagcacaagatgacaacctccttccaccaggcctaccaggaacgcttt tccgagataattggtggccaccatacctccatgagtgacctgctgtttgggaaccaggcc gggccggagcagttctcagcctggatggcctcactgctggacagacccggcctggtggac tacaccctggagcctctgcatgtgctcctggagagccaggacccacggcgggaggcgctg aggcaggctgtgagcaagtacgtgatggacagagcccgttggaagaactgcagcaggccc tgccccccggggcagcagaagagcccccacaacccatgccactgtgtgtgccacaactcg gggatcaccaaccaggactgctgtccccggcagaggggcctggcccacttagaggttatg aacttccaggcaatgggcctgtggggagactacttcacggccacagatgcctatctgaaa gtcttctttggaggccaggagcagagaacctacacggtgtggaacaataataaccccacg tgggtgacgcggctggacttcgggaacgtgctcctgtccacgggggggcccctgagggtt caggtctgggaccaagactatggctgggatgatgacctccttggcacctgtgaccagaaa gcacagtctggctcacatgaggtcaggtgcaacctgtcccacggtcacctgagattctcc tacattgccaagtgcttgcctcacctgacgggggcaacctgcctggagtatgccccccat ggtcgtctgggagagcctccaggaaaccggagtgggccagtgtggtga

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