Canis lupus familiaris (dog): 489208 Help Entry 489208            CDS       T01007                                  Symbol ITGA2 Name (RefSeq) integrin alpha-2   KO K06481   integrin alpha 2 Organism cfa  Canis lupus familiaris (dog) Pathway cfa03271   Virion - Rotavirus cfa04145   Phagosome cfa04151   PI3K-Akt signaling pathway cfa04510   Focal adhesion cfa04512   ECM-receptor interaction cfa04611   Platelet activation cfa04640   Hematopoietic cell lineage cfa04810   Regulation of actin cytoskeleton cfa04820   Cytoskeleton in muscle cells cfa05165   Human papillomavirus infection cfa05200   Pathways in cancer cfa05205   Proteoglycans in cancer cfa05222   Small cell lung cancer cfa05410   Hypertrophic cardiomyopathy cfa05412   Arrhythmogenic right ventricular cardiomyopathy cfa05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:cfa00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03271 Virion - Rotavirus     489208 (ITGA2)  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     489208 (ITGA2)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     489208 (ITGA2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     489208 (ITGA2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     489208 (ITGA2)   09142 Cell motility    04820 Cytoskeleton in muscle cells     489208 (ITGA2)    04810 Regulation of actin cytoskeleton     489208 (ITGA2)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     489208 (ITGA2)    04611 Platelet activation     489208 (ITGA2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     489208 (ITGA2)    05205 Proteoglycans in cancer     489208 (ITGA2)   09162 Cancer: specific types    05222 Small cell lung cancer     489208 (ITGA2)   09172 Infectious disease: viral    05165 Human papillomavirus infection     489208 (ITGA2)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     489208 (ITGA2)    05412 Arrhythmogenic right ventricular cardiomyopathy     489208 (ITGA2)    05414 Dilated cardiomyopathy     489208 (ITGA2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:cfa04147]     489208 (ITGA2)    04515 Cell adhesion molecules [BR:cfa04515]     489208 (ITGA2)    04090 CD molecules [BR:cfa04090]     489208 (ITGA2) Exosome [BR:cfa04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    489208 (ITGA2)   Exosomal proteins of bladder cancer cells    489208 (ITGA2) Cell adhesion molecules [BR:cfa04515]  Integrins   Integrin alpha subunits    489208 (ITGA2) CD molecules [BR:cfa04090]  Proteins   489208 (ITGA2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_3 VWA_2 FG-GAP_2 FG-GAP_3 ITGAX-like_Ig_3 HisK_sensor Integrin_alpha Motif Other DBs NCBI-GeneID:  489208 NCBI-ProteinID:  XP_005619391 Ensembl:  ENSCAFG00000018423 VGNC:  42123 UniProt:  A0A8C0S0G4 A0A8I3MC22 LinkDB All DBs Position 4:complement(61941741..62043869) Genome browser AA seq 1179 aa AA seqDB search MRPGRAGGAPLRLLLVLGQGILNCCMAYNVGLLEAKIFSGPSSEQFGYAVQQFINPKGNW LLVGSPWSGFPENRMGDVYKCPIDLSAATCEKLNLETATSIPNVTEMKTNMSLGLTLTRN MGTGGFLTCGPLWAQQCGSQYYATGVCSDVSPDFQILTSFAPAAQTCPSLIDVVVVCDES NSIYPWEAVKNFLEKFVQGLDIGPKKTQVGLIQYANKPRVVFNLNTFKTKAEMTEATSQT YQYGGDLTNTFKAIQYAKDFAYAAAAGGRPGATKVMVVVTDGESHDGSMLKAVIDQCNND NILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIF SIEGTIQGGDNFQMEMSQVGFSADYSPQKDILMLGAVGAYGWSGTVVQQTSHGHFIFPKQ AFDQILQDKNHSSYLGYSVAAISTGKDIHFVAGAPRANYTGQIVLYSVDENGNVTVIQAH RGDQIGSYFGSVLCSVDVNKDTITDVLLVGAPMYMNDLKKEEGKVYLFTITKGVLNWHQF LEGPNGVENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGTIRMRYSQ KILGSNGAFRSQLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVSVDASFT PDKITLFNKNADITLKLCFSAKFRPTKQNDQVAIIYNITIDANLYSSRVTSRGLFKENNE RCLQKNMLISQAQSCAEYTINIQKPSDVVNSLDLYVNISLEHPGTSPALEAYSEKAKVFS IPFYKDCGDDGVCISDLVLNVQHLSATQDQPFIVSNQNRRLTFSITLKNKRESAYNTRIV VDFSENLFFASWSMPVDGTEVTCQIASSQKTVTCDVGYPALKREQQVTFTINFDFNLQNL QNQASVSFQALSESYEENKADNLVNFKTPLRYDADIHITRSTNINFYEVSSDGNVPSIVH SYEDIGPKFIFSIKVTTGSVPVSMASVIIHIPQYTKEKNPLMYLTEVHADQAGDISCNAK INPLKIGHTSPSVYFKNENFRHIKDLNCRTASCSNVTCWLKDLQVKGEYFLNVSTRIWNG TFAASTFQTVQLTASAEIDTYNPQIYVIEENTVTIPITIMKPHEKAEVPTGVIIGSVIAG IILLLALVAVLWKLGFFKRKYEKMSKNADEIDETTELNS NT seq 3540 nt NT seq  +upstreamnt  +downstreamnt atgcggccgggacgcgcagggggcgcgccgctgcggctgctgctggtgctcggtcaaggc attttaaattgttgtatggcatacaatgttggtctcctagaagcaaagatattttccggt ccttcaagtgaacagtttggctatgcagtccagcagtttataaatccaaaaggcaactgg ttactggttggttcaccttggagtggctttcctgaaaaccgaatgggagatgtgtataaa tgtcctattgatttgtccgctgctacatgtgaaaaactgaatttggaaactgccacaagc attcccaatgttaccgaaatgaaaaccaacatgagccttggcttgacactcacaaggaac atgggaaccggaggatttcttacgtgtggtcccctgtgggcacagcagtgtggaagccaa tactacgccaccggtgtttgttctgatgtcagtcccgattttcagatcttgaccagcttt gcacctgcagcccagacttgcccttccctcatagatgttgtggttgtatgtgatgaatca aacagtatctatccctgggaagcagtaaagaattttttggaaaaatttgtccaaggcctg gatataggccccaaaaaaacacaggtggggttaattcagtatgccaacaaaccaagagtt gtatttaacctgaacactttcaaaaccaaagctgaaatgactgaagcaacatcccagaca taccaatatggtggagacctcacaaatacattcaaagcaattcaatatgcaaaagatttt gcttatgcagcagctgctggaggacgaccaggtgccaccaaagtaatggtggttgtaact gatggtgaatcacatgatggttcaatgttgaaagcggtgattgatcaatgcaacaatgac aatatactgaggtttggcatagcagttcttgggtacttaaacagaaatgcccttgatact aagaatttaataaaagaaattaaagcaattgccagtattccaacagaaagatattttttc aacgtgtctgatgaagcagctctattagaaaaggctggaacactgggagaacaaattttt agcattgaaggtactattcaaggaggagacaacttccagatggaaatgtcacaagtggga ttcagtgcagattactctcctcaaaaggatattctgatgctgggtgcagtaggagcttat ggctggagcgggactgttgtccagcagacatctcatggacattttatctttcctaaacaa gcctttgaccaaattctgcaagataaaaatcacagttcatatttaggttactcggtggct gcaatttctactggaaaagacatccactttgttgctggtgctcctcgggcaaattatact ggccagatagtgctatacagtgttgatgagaatggcaatgtcacagttattcaggctcac cgaggtgaccagattggctcctattttggcagtgtgctgtgctcagtcgatgtgaataaa gacaccattacagatgtactcttggtgggtgcaccaatgtacatgaatgacctaaagaaa gaagaaggaaaagtctacctgtttactataacaaagggcgttttgaattggcaccagttt ctcgaaggccccaatggtgttgaaaatgctcggtttggttcagcaattgcagctctttca gatatcaatatggatggctttaatgatgtaatagttggttcgcctttggaaaatcagaac tctggggctgtgtatatctacaatggtcacgagggcaccattcgcatgagatattcccag aaaatcttgggatccaatggagcctttaggagccagctccagtactttgggagatctttg gatggctatggtgatttaaatggggattccatcactgacgtgtccattggtgcctttggg caagtggttcagctctggtcacaaagcattgctgatgtatctgtggatgcttcattcaca ccagataaaattactttgttcaacaagaatgctgacataacactcaagctctgtttcagc gccaagtttagacctactaagcagaacgatcaagtggccattatatacaatatcacaatt gatgcaaacttatattcatccagagtaacctccagaggtttatttaaagaaaataatgaa aggtgtttgcaaaagaatatgctcataagtcaagcacagagttgcgctgagtacaccatc aacatacagaagccctctgatgttgtcaactctttggatctgtatgtgaacatcagcctg gaacaccctggcaccagccctgccctcgaagcctactctgaaaaggccaaagtcttcagt atccctttctacaaggactgtggggatgatggagtttgcatctcagatctagttctgaat gtccaacatctgtcagctactcaagatcaaccttttattgtcagcaaccaaaacagaagg ttaacattttcaataaccctgaaaaacaaaagggaaagtgcatacaacactagaattgtt gtggatttttcagaaaatttgttttttgcttcctggtccatgccggttgatgggacagaa gtaacatgccagattgcttcatctcagaagactgtcacctgtgatgtaggctaccctgct ttgaagagggagcaacaggtgactttcactattaactttgacttcaatcttcaaaacctt cagaatcaggcatctgtcagtttccaagccttaagcgaaagctatgaagagaacaaggca gataatttggtcaacttcaaaactcccctgcggtacgacgccgatattcacataacaaga tccaccaacataaatttttatgaagtctcttcagatgggaatgttccttctatcgtgcac agttatgaagatattggtccaaaattcatcttctccattaaggtaacaacaggaagtgtt ccagtaagcatggcatctgtaatcatccacatccctcaatacaccaaagaaaagaaccca ttaatgtatctgactgaggtgcacgcagatcaggccggtgacatcagttgtaatgccaaa ataaatccactgaaaatcggacatacatctccttctgtgtatttcaagaatgaaaatttc cggcacataaaagacttgaactgcagaactgcttcatgtagcaatgttacctgctggctg aaagacctccaggtcaaaggagagtacttccttaacgtgtctaccagaatttggaacggg acttttgcagcatcaactttccagactgttcagctgacagcatctgcagaaatcgacacc tataaccctcagatatatgtgatcgaagaaaacacagtcacgattcccatcacgataatg aaaccccatgagaaagctgaagtacctactggagttataataggaagcgtaattgctgga ataattttgctattagctctggttgcagttttatggaagcttggcttcttcaaaagaaaa tatgaaaaaatgtccaaaaatgcagatgagattgatgagaccacagaactcaacagctga

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