Canis lupus familiaris (dog): 489458
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Entry
489458 CDS
T01007
Symbol
ALOX15
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX15
KO
K00460
arachidonate 15-lipoxygenase [EC:
1.13.11.33
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00590
Arachidonic acid metabolism
cfa00591
Linoleic acid metabolism
cfa01100
Metabolic pathways
cfa04148
Efferocytosis
cfa04216
Ferroptosis
cfa04217
Necroptosis
cfa04726
Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
489458 (ALOX15)
00591 Linoleic acid metabolism
489458 (ALOX15)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
489458 (ALOX15)
09143 Cell growth and death
04216 Ferroptosis
489458 (ALOX15)
04217 Necroptosis
489458 (ALOX15)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
489458 (ALOX15)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.33 arachidonate 15-lipoxygenase
489458 (ALOX15)
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Paralog
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
489458
NCBI-ProteinID:
XP_546576
Ensembl:
ENSCAFG00000015949
VGNC:
37811
UniProt:
A0A8I3P5X5
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Position
5
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AA seq
663 aa
AA seq
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MGLYRIRVSTGSSLCAGSQNQVQLWLVGQHGEAEIRKRLRPARGQETEFKVDVEEHLGPL
LFVKLQKWHFLQDDAWFCNWISVQGPGDSGEEFTFPCYRWVEGSGILSLPEGTGRTVVDD
PQDLFKDYREKELEKKRNLYRWGNWKDGLILNVVGATISDLPADERFLEDKRIDFEASLA
KGLADLAIKDSLNLFTCWNDLDDFNRIFWCDQSKLAKKVRDSWKEDALFGYQFLNGANPM
ILRRSRQLPARLKFPPGMEELQIQLEQELQGGRLFEADFVLLDGIKANVILCSQQYLAAP
LVMLKLQPDGKLLPMVIQLQLPRVGCPPPPLFLPTDPPMVWLLAKCWVRSSDFQIHELQS
HLLRGHLMAEVITVATMRCLPSIHPIFKLLIPHLRYTLEINVRARTGLISDNGVFDQVVS
TGGGGHVELLQRARAFLTYRSFCPPTDLADRGLLGVESSFYAQDALRLWEILYRYVQGIV
YLHYKTNEAVRDDLELQTWCREITEVGLRGAQDQGFPNSLQSRDQMCHFLTMCIFTCTGQ
HSSTHLGQLDWYTWVPNAPCTMRLPPPTTKDVTLETVMATLPNCHQASLQMSITWQLGRR
QPVMVALGQHQEEYFSGPGPKDVLKKFREELAVLEKEIETRNAKLDMPYQYLQPSLVENS
VAI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggtctctaccgcatccgcgtgtccaccggctcctcgctgtgcgcgggctcccaaaac
caggtgcagctgtggctcgtgggccagcacggggaagcggagatccggaagcgcctgcgg
ccggcgcggggccaggagacggaattcaaggtggacgtggaggagcacctggggccgttg
ctgttcgtgaaactgcagaaatggcacttccttcaggacgacgcctggttctgcaactgg
atctccgtgcagggccccggggacagcggggaagagttcacgttcccgtgctaccgctgg
gtggaaggcagtggcatcttgagcctccccgagggcaccggccggacggtggtggacgac
cctcaagacttgttcaaggactacagggaaaaggagctggaaaagaagaggaacctgtac
cggtggggtaactggaaggatggattaatcctgaatgtcgttggggccacgatctctgac
ctccctgcagatgaacgatttctggaagataagagaattgattttgaggcttcgctggcg
aaggggctggcagacctagccatcaaagactctttaaatctcttcacttgctggaatgat
ctggatgacttcaaccgaattttctggtgtgaccagagcaagttggctaagaaggtgcgg
gactcctggaaagaagacgccttgtttgggtaccagtttctcaacggtgctaaccccatg
atactgaggcgctccaggcagctgcctgcacgcctgaagttccctccggggatggaggag
ctgcagatccagctggagcaggagctccagggaggcaggctgttcgaggcggacttcgtg
ctgctggacgggatcaaggccaatgtcatcttgtgcagccagcagtacctggccgcccct
ctggtcatgctgaaactgcagcctgatgggaaactgttgcccatggtcatccagctccag
ctgccacgtgtgggatgccctccaccaccgcttttcctgcccacggatcccccgatggtc
tggctcctggccaagtgctgggtccgtagctctgactttcagatccacgagctgcagtct
caccttctgcggggacacttgatggcagaggtcatcaccgtggccaccatgaggtgcctt
ccgtccatacaccccatcttcaagcttctcatcccccatctgcgctacaccttggaaatt
aacgttcgggccaggacggggctcatctctgacaacggtgttttcgaccaggtggtgagc
acaggtggcggaggccacgtggagctgctccagcgagctagagccttcctaacctaccgc
tccttctgtcctcccactgacctggccgaccgggggctcctgggagtcgagtcttccttc
tatgcgcaggatgctctgcggctttgggaaatcctctaccgctatgtgcagggcatcgtg
tatctccactacaagacgaacgaggctgtgagagatgatctggagctgcagacttggtgt
cgagagatcactgaggtcgggttgcggggggctcaggaccaagggttccccaactcctta
cagtcccgcgaccagatgtgtcactttctcaccatgtgtatattcacctgtactggccag
cactcgtccacccacctgggccagctggactggtacacttgggtccctaacgcgccctgc
accatgcggctgccgcctcctaccaccaaggacgtgacactggagacagttatggcaaca
ctgcccaactgccatcaggcctcgctgcagatgtccatcacctggcagctgggccgccgc
cagcctgtgatggtggctctgggccagcaccaggaggagtatttttcaggccctggaccc
aaggacgtgctgaagaagttcagggaggagctggctgttttggagaaggaaatcgagacc
cggaatgcaaagctggacatgccctaccagtacctgcagcccagcctggtggaaaacagt
gtggccatctga
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