Canis lupus familiaris (dog): 489507 Help Entry 489507            CDS       T01007                                  Symbol DNAH9 Name (RefSeq) dynein heavy chain 9, axonemal   KO K10408   dynein axonemal heavy chain Organism cfa  Canis lupus familiaris (dog) Pathway cfa04814   Motor proteins cfa05014   Amyotrophic lateral sclerosis cfa05016   Huntington disease cfa05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:cfa00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     489507 (DNAH9)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     489507 (DNAH9)    05016 Huntington disease     489507 (DNAH9)    05022 Pathways of neurodegeneration - multiple diseases     489507 (DNAH9)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:cfa03037]     489507 (DNAH9)    04812 Cytoskeleton proteins [BR:cfa04812]     489507 (DNAH9) Cilium and associated proteins [BR:cfa03037]  Motile cilia and associated proteins   Dynein arm    489507 (DNAH9) Cytoskeleton proteins [BR:cfa04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      489507 (DNAH9) SSDB OrthologParalogGFIT Motif Pfam:  MT DHC_N1 AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_1 AAA_lid_11 Dynein_heavy AAA_5 Dynein_AAA_lid DYN_lid AAA_16 AAA_22 Sigma54_activat DYH2-5-8_CC nSTAND6 Motif Other DBs NCBI-GeneID:  489507 NCBI-ProteinID:  XP_038372432 Ensembl:  ENSCAFG00000017769 VGNC:  40019 UniProt:  A0A8P0NJ80 LinkDB All DBs Position 5:35868460..36197847 Genome browser AA seq 4489 aa AA seqDB search MPGAEERAARAAESGDPGRGAADPRLRLLGAYVARSLRPAAGVWERCAGTSEAERLLHAF LGREAAGGPRPPLLLVVRPGPGGLAVRPGLDTGPEAGPPRAKGLFFLRTGPEPPGPRSLR GAVLCGDLPAAPLQHLAAMFSEVVIPILANEKNHLDWPHVLRQDVQRHAHSLQCDLLVIL EQVKGKTLLPLPLGAAKLEFEASPSGTILDCTDKSIIYALESAVIQWSRQVQVVLKRESG QALLQGESPTPKVELEFWKSRSEDLEYIYNQLRMIEVRGMARLLDKLQSSYFAAFQAMFR DVQAALAEAQDIRIHLMPLSHHLEILESLEFPEVKPQLQPLLHVVCLIWATCASYRSPGR LTVLLQEICNLLIQQASNYLSPEGLLRGEVEESQRKLQVAMDTLNFFKQVFQDRRENLHT YFKENQKVQEWDFQSALVFVRLDGFLGRLVMVQDLLKTILDFHKLGKLEFSGIRGNALSQ QVQQMHGEFQELYRVFEESSYDCLDPQSTEFENDVSEFNQRVEDLDRRLGTVFSQAFDDA PGLEHAFKLLDIAGKLLERPLVAQDASEKYLLLIHMFIKDLDTVRAIYSQRVQEEAELGF SSTHKNMPAMAGGLHWAQELRQRIQGPSTNFRRLAHPCMESAEGKRMTQKYEDMLSLLEK YEARLYEDWCQTVSEKSQYNLSRPLLKRDPETKQITVNFSPQLISVLKEMSYLEPRQKQH VPETAAVLFSSREFYRQLVAKLELMANWYNKIVKTLIEVEFPLVEEELQGIDLHLRAAEE TLSWKTEGIWDYVIQITDSIRDLEQRIQKAKDNVEEIQNIIKTWVSPIFKRKDGKRECLL SMDDQHDQLEKYYNLIKESGLQIHALVQENLGLFVADPTSNIWKTYVNYIDEMLLDGFFL AIECSLKYLLENTECRTGLTPIFEAHLSLAIPELVFSPSLEYGVKGGFYDAIEGLITSIF GVSSLMPRLSPHTGSPHYQADIEGMAHLASMRTKLLDRVQGMMALCCGYRDTFSQYSYLY VEDRKEILSQFLLYGHVLTPEEMEAHAEDGIPENPPLLHQFKAQIDSYEKLYEEVCRLEP IKTFDSWMKIDVRPLKASLLNIIKRWSLMFKQHLVDYVTDSLADLEVFIKNSESGMLKKV EKGDFEGLVEVMGHLMALKERQSSTDEMFEPLKQTIELLKTYEQELPEMVFKQLEELPEK WSNAKKVAVTVRQQVAPLQANEVAVLRQRCSAFDIKQQQFREQFCREAPFRFDSIDPHQV LDARHTEIQQLESTMASISEVASLFEVNVPDYKQLKQCRKEVCQLKELWDTIGMVTSSIR AWETTLWKEVNVEVLDGECKRFARHIRNLDKEVRAWDAFTGLESMVLNTLTSLRAVAELQ NPAVRERHWRQLMRATGVSFTMGEGATLAHLLQLRLHHFEDEVRDIVDKAMKEMAMEKTL KELQTTWAGMEFQYEPHPRTGVPQLQSDEDLIEVLEDNQGQLQNLMMSKHIAFFLEEVSS WQKQLSTAHAVISTWFDVQRTWSHLESIFIGSEDIRAQLPQDSKRFEGIDLDFKELAYDA QKTPNVVEATNKPGLYEKLEDLQSRLYLCEKALAEYLDTKRLVFPRFYFLSSSDLLDILS NGTAPQQVQRHLSKLFDNMAKMQFQLDTSEKPTKISLGMYSKEGEYVAFSEPCDCSGQVE IWLNRVLAHMRATVRHGMTEGVVAYEEKPREQWLFDYPAQVALTCTQIWWTTEVGIAFAR LEEGYENAMKDYFKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQK VDSAQSFLWLSQLRHRWDDEAKHCFANICDAQFLYCYEYLGNTPRLVITPLTDRCYITLT QSLHLTMSGAPAGPAGTGKTETTKDLGRALGVMVYVFNCSEQMDYKSCGNIYKGLAQTGA WGCFDEFNRISVEVLSVVAMQVKSIQDAIRDKKQRFNFLGEEISLEPSVGIFITMNPGYA GRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFIEARSLARKFITLYQLCKELLSKQ DHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDIPVFMGLIGDL FPALDVPRRRDLNFEALVRKAVVDLKLQAEDSFVLKVVQLEELLAVRHSVFVVGSAGTGK SQVLKSLHKTYQIMKRRPVWADLNPKAVTNDELFGIINPATREWKDGLFSSVMRELANIT HDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMRLLFEISHLRTATPA TVSRAGILYLNPADLGWNPPVSSWIDKREIQTERANLTILFDKYVPTCLDTLRTRFKKII PIPEQSMVQMLCHLLECLLTEEDIPADSLKETYELYFVFAAIWAFGGAMIQDQIVDYRAE FSKWWLMEFKTIKFPSQGTIFDYYIDPETKKFEPWSKLIPQFEFDPEMPLQACLVHTSET IRVCYFMERLMALRRPVMLVGAAGTGKSVLVGSKLASLDTEEHLVKHVPFNYYTTSAMLQ AVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRN KLSLKEIRNVQYVSCMNPTAGSFTINPRLQRHFSILALSFPGPDALASIYGTILTQHLML GRFPVSLQKSSPQLISLALTFHQKIATTFLPTAIKFHYVFNLRDFANIFQGILFSSVECV KSTQDLVKLYLHESNRVYRDKMVEEKDFDLFDKIQTEVVKKIYDDIDETVEQTQSLNMYC HFASGIGEPKYMPVQSWGLLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESP RGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKTGLKNLS TVFLMTDAQVADEKFLVLINDLLASGEIPDLYSDDEVENIISSVKNEVKSQGLVDNRENC WKFFINRVRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAINWFHEWPQQALESVSLRFL QNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHR NRKELKSKMERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGIETEK VSREKAIADEEERKVAVIMLEVKQKQKDCEEDLAKAEPALAAAQAALNTLNKTNLTELKS FGAPPPAVSNVTAAVMTLTAPGGRVPKDRSWKAAKVTMAKVDGFLDSLINFDKEHIHESC LKAIRPYLQDPDFNPELVATKSYAAAGLCSWVVNIVRFYEVFCDVEPKRQALSRATSDLT AAQEKLAAVKAKIAHLNENLAKLTAKFEKATADKLKCQQEAEVTAGTISLANRLVGGLAS ENVRWAEAVQNFRQQESKLCGDILLTTAFVSYLGFFTKRYRQSLMDRTWRPYLSQLEVPI PVTPTLDPLRMLTDDADVATWHNEGLPADRMSTENATILLNCERWPLMVDPQLQGSRWIK TKYGENLRVTQIGQKGYLQTIERALEAGDVVLIENLEESIDPVLGPLLGREVIKKGRFIK IGDKECEYNPKFRLILHTKLANPHYQPEMQAQATLINFTVTRDGLEDQLLAAVVSMERPD LEQLKSDLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGDTVLVENLETTKQTAAEVEKK VQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVEKA APDESLKKRVTNLIDSITFSVYQYTTRGLFECDKLTYLAQLTFQILLVNQEIDASELDFL LRSPGQTGVTSPVGFLSHQAWGSIKALSSMEGFYNLDRDIEGSAKSWKKFVESECPEKEK FPQEWKNKTALQRLCMMRAMRPDRMTYAIRDFVEEKLGSKYVAGRAPDFATSFEESGPAT PMFFILSPGVDPLKDVENHGKKLGYTFNNRNFHNVSLGQGQEVVAEAALDLAAKKGHWVI LQNIHLVAKWLGTLEKKLAEHSENSHPELRVFISAEPAPSPEGHIIPQGILENSIKITNE PPTGMHANLHKALDNFTQDTLEMCSREMEFKSILFALCYFHGVVAERRKFGPQGWNRSYP FNTGDLTISVNVLYNFLEANTKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFIRP EMLEGELSLAPGFPLPGNLDYTGYHQYVDAQLPAESPYLYGLHPNAEIGFLTQTSEKLFR TVLELQPRDSHAGDRAGATREEKVKALLEEILERVTDEFNMAELMAKVEERTPYIVVAFQ ECERMNILTREIQCSLRELDLGLKGELTMTSDMETLQNALYLDTVPESWTRRAYPSTAGL GTWFLDLLNRIKELEAWIGDFAMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDKMALQ CDVTKKNREDFKSPPREGAYIHGLFMEGACWDIQAGIITDAKLKDLTPPMPVMFIKAIPA DKQDHRSVYPCPVYKTCQRGPTYVWTFNLKTKEKPSKWVLAGVALLLQT NT seq 13470 nt NT seq  +upstreamnt  +downstreamnt atgccgggcgcggaggagcgggcggcgcgggctgccgagagcggcgacccggggcgcggc gccgccgacccgcgcctgcgactcctgggggcctacgtggcccggagcctgcggccggcc gccggagtctgggagcgctgcgcgggcacgtccgaggcggagcggctgctgcacgccttc ctgggccgcgaggctgcggggggcccgcggccgccgctgctgctggtggtgcggcccggg cccgggggcctggcggtgcggcccgggctggacacggggcccgaggccggcccgcctcgc gccaaggggctcttcttcctgcgcaccgggcccgagccgccggggccccgcagcctccgc ggcgccgtgctgtgcggggacctgcccgccgcccccctgcagcacctggccgcgatgttc tccgaggtggttatccccattttggccaatgagaagaatcacctggactggccccacgtg ctccgtcaggatgtccagcggcacgcccacagcctccagtgtgacctcctggttatcctc gagcaagtgaaggggaaaactttgcttcctctcccactgggcgcagcaaaactggagttt gaggcttctcccagcgggaccatcttggattgcacagataagtccatcatctacgccctc gagtcggccgtgattcagtggagccgccaagtccaagtggtgctcaagagagagtcgggc caggcactcctgcaaggggagagccccacccctaaggtggagttggagttctggaagagc aggtctgaggatctggaatacatttataatcaactgagaatgatagaagtgaggggcatg gccaggctcctggacaagcttcagagcagctactttgcagctttccaagccatgttcaga gacgtccaagcagccctggcagaggcccaggacatccgaatacacctgatgccactctcc caccacctggagatcctcgagagcctggagtttcccgaggtgaagccacagctgcagcct ctgctccacgtggtctgtctcatctgggctacatgcgcgtcctaccgctctccggggcgg ctcaccgtgctgctccaagagatctgcaacctcctcatccagcaggcgtctaattatctc agcccagagggcctcctgagaggcgaggtggaggagagccagagaaaactgcaagtggcg atggacacgttaaacttcttcaagcaggtgttccaggacaggagggagaatctgcatact tactttaaagagaaccagaaagtccaggagtgggatttccagtcggctttggtctttgtg cgattggatggcttcctggggcggctggtcatggtgcaggatctcctgaagacaatcctg gatttccacaaactgggaaagcttgagtttagtggaatccgaggaaacgccctgagtcag caggtccaacaaatgcatggtgaatttcaagagctgtacagggtcttcgaagagtcttcc tatgactgcttggacccccagagcacggaatttgaaaatgacgtgtctgaatttaaccag agagtagaagatcttgaccgaagactggggactgtgttcagccaagccttcgatgatgcc cctggtttggagcatgcctttaagctgctagacatagcagggaaacttctggaaagaccg ctggtggcacaggatgcctctgaaaaatacctgctgctcatccacatgttcatcaaagac ttggatacagtgagggcaatctacagtcagcgtgtccaggaagaggccgaacttgggttc tcctccacgcacaagaacatgccagccatggccgggggtctccactgggcgcaggagctg aggcagcgcatccagggtccctccaccaacttcagacgccttgcacatccttgcatggaa tctgccgaaggaaagcgaatgacccagaaatatgaagatatgctctcgttgctggaaaag tacgaggcaagactttatgaggactggtgtcagacagtgtcagagaagtcccaatacaac ctttcccggccacttctgaaacgtgaccctgagacaaagcagatcactgtcaactttagc ccccagctgatttccgtgctgaaggaaatgagttatcttgaacccaggcagaagcagcat gttcctgagacagcagcagtcttgttctcctccagggaattctatcggcagcttgtggct aagttggagctgatggcaaattggtacaataaaattgtgaaaactcttatagaggtggaa tttcccttagtggaggaagagctgcagggtatcgacctccacctaagagctgcagaggag actctgagctggaaaacagaaggcatctgggattatgtcattcaaatcactgatagcatc cgtgatctcgaacaaagaattcagaaggctaaagacaatgtggaagagattcaaaacatc attaaaacatgggtgtctccaatatttaaaagaaaagatggaaaaagggaatgccttctt tccatggatgatcagcatgatcagctggaaaaatactacaatctcatcaaagaatctgga cttcagattcatgcccttgttcaggaaaacctaggtctgtttgtggcagacccaacctct aatatctggaagacttacgttaactacatcgatgagatgttgctggatgggttttttctt gctattgagtgctccctcaagtacctcctggaaaacactgaatgcaggacaggactcact ccgatatttgaagcacacctgagcttagccataccagaattagttttctctccctccctg gagtatggagtgaagggtggcttctatgacgctattgaggggcttattactagcattttt ggagtatcgtctttgatgccacggctctccccacacactggctcgccccactaccaggct gacatagagggcatggcccacttggcgagcatgaggaccaagcttctggacagggttcag ggtatgatggccctctgctgtggctatcgggacaccttcagccaatattcctacctctat gtggaggaccggaaggagattctgagccagtttctgttgtatgggcatgtcctcaccccc gaggagatggaagcccatgcagaagatggcatcccagagaatcctcctctcctccatcag tttaaagcacagattgactcctatgaaaagctctatgaagaagtgtgtagactggagccc atcaaaacgtttgatagctggatgaaaattgatgtccggcctcttaaagcatctctgcta aatataattaagaggtggagcctcatgttcaaacagcatcttgttgactatgtcactgac agcctggctgaccttgaagtgtttataaaaaacagcgagagcggcatgctcaagaaagtt gaaaaaggagatttcgaaggactggttgaggttatgggacaccttatggccctgaaagaa aggcagagcagcactgatgagatgtttgaacccttaaagcagactattgaattgctgaag acctacgaacaagaattgccagaaatggtgtttaagcaactggaggagctgcctgagaag tggagcaacgcgaaaaaggtggcagtcaccgtgagacagcaggtggccccgctgcaggca aatgaagtggccgtcctccgccagaggtgctcagcctttgacatcaaacaacagcagttc cgggagcagttctgcagggaagcccccttcaggtttgatagcattgaccctcatcaagtt ctggatgccaggcacacagagatccagcagctggaatctaccatggcctccatttctgag gttgccagcttgtttgaggtcaacgttcccgactacaagcagctgaagcagtgcaggaag gaggtgtgccagctgaaggagctctgggacaccattgggatggtgacctccagcatccga gcctgggagaccaccctgtggaaggaggtcaacgtagaggtcctggacggggagtgtaaa cggtttgccaggcacattcggaacctggacaaggaggtcagggcctgggacgcgttcacg ggcctggagagcatggtgttgaataccctgacctccctgagggcggtcgccgagctgcag aacccagctgtccgggagcggcactggaggcagctgatgcgggccacgggtgtgagcttc accatgggcgagggtgccaccctggcacacctcctacagctccggctgcaccactttgag gacgaggtccgggacattgtggacaaagccatgaaagagatggccatggagaagaccctg aaggagctgcagaccacctgggctggcatggaattccagtatgagccccacccgcggacc ggcgtcccccagctgcagtcagacgaggacctcatcgaggttctggaggataaccaaggg cagctacagaacctaatgatgtccaagcacattgccttcttcttggaggaagtgtccagc tggcagaagcagctgtccacggctcatgccgtcatctccacctggttcgacgtgcagcgt acatggtcgcatctggagagtatattcatcggctccgaagatatccgggctcagctgccc caggattctaaacgatttgaaggcattgaccttgactttaaagaactagcttatgatgcc cagaagactcccaatgtagtggaagccaccaacaaaccaggtctttatgaaaaactggaa gatcttcagagcaggttatacctgtgtgagaaggccctggcggagtacctggataccaaa aggcttgtcttccctaggttttactttctgtcctcttctgacctgttagacatcctctcc aatggcacagctccgcaacaggtccagcgccatctttccaaactcttcgacaacatggcc aagatgcagttccagttggacaccagtgaaaaaccaaccaagataagtctcggcatgtac agcaaggaaggagaatatgtggccttcagcgagccctgtgactgcagcggtcaggtagaa atatggttgaaccgtgtgcttgcccatatgagggccacagtgaggcatgggatgactgaa ggtgtggttgcctatgaagaaaagccaagggaacagtggctctttgactatccagctcag gtggccctgacttgcactcagatctggtggaccacagaggtgggcattgcctttgccagg ctggaggaaggctacgagaacgccatgaaggactatttcaagaagcaagtggcccagctc aaaacccttatcaccatgctaattgggcagctctccaaaggggaccggcaaaagatcatg accatatgcaccattgatgtgcatgcccgggatgtggtggccaagatgattgctcagaag gtggacagtgctcagtccttcctctggctgtcccagctgcggcatcgttgggatgatgag gccaaacactgctttgccaacatctgtgatgcacagtttctctactgctatgagtacctg ggaaatacacctcgcctggtgatcacacctctgacagacagatgctacatcaccctcacc cagtctctgcacctgaccatgagtggagctccagcaggacctgcaggcacaggcaaaaca gaaaccaccaaggacctgggccgagcgctgggtgtcatggtgtatgtgttcaactgctcc gagcagatggactacaagtcttgcggcaacatctacaaaggcctcgctcagactggtgcc tggggctgttttgatgagtttaaccgaatctctgtggaagtcttgtcggtggtagccatg caggtaaaaagcattcaagatgcaatccgagataagaaacaacgattcaacttccttggg gaggagattagcctggaaccttcggtggggatcttcatcaccatgaacccgggttacgct ggccgcacggaacttccagagaatctcaaggctcttttcaggccttgtgcaatggtggtt ccagactttgagttgatctgcgagatcatgctggtggcagaaggattcattgaagcacga tcattagccagaaagttcatcaccctttaccagttgtgcaaagagctgctctctaaacag gatcactatgactggggcctgcgggccatcaagtctgtgttggtggtggcaggatccctg aagcgaggagaccctgaccgccctgaggaccaagtcctgatgcgctccttgcgagatttc aacatccccaagatcgtgaccgatgacataccagtgttcatgggcctgattggggacctc tttcctgccctggatgtccctcggaggagagacctcaactttgaagcgttggttaggaag gcggtggtggacctgaagctccaggctgaggacagctttgtactcaaggtagtccagctg gaggagctcctggcagtgcggcactctgtgttcgtggtgggcagcgccggaactggaaag tctcaggtgctgaaatccttacacaagacctaccagatcatgaaacgccgccccgtctgg gctgacctcaaccccaaagcagtcacaaacgatgaactctttggcatcatcaatccggcc accagagaatggaaggatggactcttctcgtctgtcatgcgggagcttgccaacatcacc cacgacgggcccaagtggatcttactggatggcgacatagatccgatgtggattgaatct ctgaacaccgtcatggatgataacaaggtcctgaccctggcaagcaatgagaggatcccc ctgaatcccacaatgagactgctcttcgagatcagccacctgcgcacggccacaccagca actgtctccagagcaggaatcctgtacctcaatccagcagacctgggatggaaccctccg gtgagcagctggattgacaagagggaaatccagacagagagagccaacctaaccattctg tttgacaagtacgtcccaacgtgcttggacacgctcagaaccagatttaagaagataatt ccaatcccagaacagagcatggtccagatgctgtgccaccttctcgagtgtctcctgacc gaggaggacatccccgcggactccctcaaggaaacctatgagctgtattttgtgtttgct gccatctgggcttttggtggagcaatgatccaagatcagattgtggactaccgggcagag ttcagcaagtggtggctgatggagttcaagaccatcaagttcccctcccagggaaccatc tttgactactacatagatccagagacaaagaaatttgagccttggtccaagctcatcccc cagtttgaatttgaccccgagatgcctctgcaggcttgtttggtacacacaagtgaaacc atccgagtgtgctacttcatggagcggcttatggcactgaggcggccggtcatgttggtg ggagccgcaggcacgggcaagtcggtgctggtgggaagcaagctggccagcctcgacact gaggaacacctggtgaaacacgtgccatttaactactacaccacgtcagcaatgctgcaa gctgtcctggaaaagcctctagagaagaaggctggaagaaattatggccccccaggcaac aagaagcttatctatttcattgatgacatgaacatgcccgaggtggatgcctatgggacc gtgcagccccacaccatcatcaggcagcatttggactatggccactggtatgatcggaat aagctgtccctgaaggagatcaggaatgtgcagtatgtctcctgtatgaatcccactgca ggcagcttcaccatcaacccacggcttcagcgccacttcagtatacttgccctctccttc ccgggaccagatgccctggcatccatctacggcaccatcctgactcagcatctaatgctt gggcgcttcccagtgtccctgcagaaatctagcccccagctcatcagcctggccctgacc ttccaccagaaaatcgccaccacgttcctacccacagcgatcaaattccactacgttttc aacctcagagactttgccaacattttccagggcatcctgttctcctcagtggaatgtgta aaatccacacaggacctagtaaagctctatctgcatgaatcaaatcgagtttatcgggat aagatggtggaagaaaaggactttgatctttttgataaaatccagacagaagtggtcaag aaaatttatgatgatattgatgagactgtggagcagacccaaagcctgaacatgtattgc cattttgccagtggtattggtgaaccaaagtacatgcctgttcagtcgtggggacttttg acccaaactctggtggaagccctagagaaccacaatgaagtcaacacagtcatggatctg gttctctttgaggatgccatgcgccatgtctgtcacatcaaccgcatcttggagtcccca cggggaaatgctctgctggtcggtgtgggtgggagcggcaagcagagtctgacaaggctt gcggctttcatcagctccatggatgtattccagatcacgctgcggaaaggctaccagatc caggacttcaagatggacctggccagtttgtgtctgaaaactgggttgaaaaatctcagc acagtgtttctcatgaccgacgcccaagtggctgatgagaagttccttgtgctcatcaat gatctcctggcatctggagagatcccagacctctactctgatgatgaagttgaaaatatc ataagcagtgtgaagaatgaggtcaagagccaaggtctggttgacaacagagagaactgc tggaagttctttataaatcgggtccgacgacaactgaaggtgactctttgtttctcccct gtggggaacaagctgagagtccgcagcaggaagttcccagccattgtgaactgcacggcc atcaactggttccatgagtggccccagcaggcactggagtctgtcagcctccgcttcttg cagaacacagaaggcattgagcccacagtcaagcagtcgattagcaagttcatggctttt gtccacacaagtgtcaaccagacatcccaatcttatctgagcaatgagcagcgctacaac tatacaactcccaaatcgttcctggagttcatcagactctaccagagcttgctgcacaga aacagaaaagagctcaagtccaaaatggagcgtcttgagaacgggctgctgaagcttcac agcacctctgcccaggtggatgacctgaaggccaagctggctgcccaggaagtagagctg aagcaaaagaatgaggatgcggacaagctgattcaggtggtcggcatagagacagaaaag gtgagccgagagaaagccattgcagacgaggaggagcggaaggtggctgtcatcatgctg gaggtgaagcagaagcagaaggactgtgaggaggacctggccaaagcagagccagcactt gcagccgcccaggcagctctcaacaccctcaataagaccaacctgaccgagctgaagtcg ttcggggccccccctccagctgtcagcaacgtcacggccgcggtgatgaccctcacggcc cccgggggcagggtgcccaaggaccgcagctggaaggccgcgaaggtcaccatggccaag gtggacggtttcctggactccctcatcaactttgacaaggagcacattcacgagagctgc ctcaaggccatccggccgtacctgcaggacccggacttcaaccccgagctggtggccacc aagtcctacgcggccgcgggcctctgctcctgggtggtaaacatcgtgcgcttctacgaa gtgttctgtgacgtggaacccaagcgccaggcgctgagcagggccacctcggacctcact gccgcccaggagaagctggcagccgtaaaagccaagattgctcaccttaatgaaaacctg gccaaactcacagccaagtttgagaaagcaacagccgacaaactcaaatgtcagcaagaa gctgaagtgaccgcaggcaccatctcccttgcaaatcgtctggtgggaggacttgcctct gaaaacgtgaggtgggcagaagctgtgcagaacttcagacaacaggagagcaaattatgt ggagacatcttacttaccacagctttcgtctcatacctgggcttctttacaaagcgatac cggcagagcctcatggacaggacctggagaccctacctgagccagctggaagtccccatc ccagtcacccccaccctggatcccctgaggatgctgacggacgatgccgacgtggcgacc tggcacaacgagggcctccccgcagaccgcatgtccacggagaatgccaccatcctcctc aactgcgagcgctggccgctcatggttgacccgcagctccaaggcagcaggtggatcaag accaaatacggcgaaaacctccgggtcacccagatcggtcagaaaggctacctccaaacc atagagcgtgccctggaagctggagatgtggtgctgattgaaaacctggaagagtccatt gatcctgttctgggacccctactcgggagagaagtcatcaagaaaggacgattcattaaa atcggagacaaagagtgtgaatacaatcccaagttccggcttatccttcacaccaaactg gccaatcctcactaccagcccgaaatgcaggctcaggctaccctgatcaacttcacggtg acccgggatggcctggaggaccagctgctggcagctgtggtcagcatggagaggccagac ctggagcagctgaagtcagatctcacgaagcagcagaatgggttcaaaatcaccctgaaa acattagaagacaacctgctgtctcgcctctcgtcagcatcagggaacttcctgggggac acggtcttagtggaaaacctggagaccaccaagcagactgccgctgaagttgagaagaag gtccaggaggccaaggtaacagaagtgaaaatcaatgaggcccgagagcactaccggcca gcagctgcccgtgcctctctgctctacttcatcatgaatgacctcagcaagatccacccc atgtaccagttttctctcaaggcattcagcatcgtcttccagaaggctgtggagaaggct gctccagatgagagcctcaagaagcgcgtgactaatctgatagacagcatcaccttctct gtgtaccagtacaccacccgtgggctcttcgagtgcgataagctgacctatcttgcccag cttacctttcagatcctcctcgtgaaccaggaaatcgatgcttcggagctggatttccta cttcgatctccaggacagacaggcgtcaccagtcccgtgggcttcctctcccatcaggcc tggggtagcatcaaggcactttcatcaatggaagggttctataacctggatcgggacatt gagggatctgccaagagctggaaaaagtttgtggaatcggaatgtcctgagaaggagaag tttccacaggagtggaagaacaagacagccctgcagcgcctctgcatgatgagagccatg cgaccagaccggatgacctacgccattcgagattttgttgaggagaagttgggtagcaaa tatgtggcaggaagagcaccagactttgcgacctcgtttgaggaatcaggaccagccaca cccatgttttttatcctgtctccaggggtggaccccctgaaggatgtggaaaatcacggt aaaaagctcggatacaccttcaacaacaggaacttccacaacgtgtctctgggacaagga caggaggtagtggcggaggctgcgctggacctggctgctaagaagggtcactgggttatt ctgcagaacatccacctggtggccaagtggctcggcactctggagaagaagctggcagag cacagtgagaacagccacccagaactgagggtcttcataagtgcggagcctgcgccctcc cctgagggccacatcatcccacagggcatcctggagaactccattaagatcaccaacgag ccccccacaggcatgcatgccaacctgcacaaggccctggacaacttcactcaggacacg ctggagatgtgttcccgggagatggagtttaagagcatcctctttgctctttgttacttt cacggggtggtggcagagagacggaagtttgggccacaaggatggaatcgttcttacccc ttcaacactggggacctcaccatctctgtgaatgtgctctacaacttcctagaggccaac acaaaggtcccctatgatgatctgcgctacctctttggagagatcatgtacggaggccat atcacagatgactgggacaggaggctctgcaggacctatctggaggaattcatcagacct gaaatgctagaaggagagctgtctctggcaccagggttcccactcccgggcaacctggac tatactggctaccatcagtacgtcgatgcccagctgcctgcagaatcgccctacctctat ggcctccaccccaacgctgagatcggcttcctgacccagacgtcggaaaagctcttccgc accgtgctggagctgcagccccgggacagccacgctggagacagagcaggggccaccaga gaagaaaaggtcaaggccctcctggaagaaatcctggagcgcgtgacagatgagttcaac atggcagagctgatggccaaagtggaggaacgcaccccctacatcgtcgttgccttccag gagtgtgaacggatgaacatcctcaccagggagatccagtgctcactaagagagctggat cttggcttaaagggggagctgaccatgaccagtgacatggagaccttacagaacgcccta tacctagacacagtgccagagtcctggaccaggcgagcctacccttcaacagcaggcctg ggaacctggtttttggacctcctcaaccgaatcaaagagttggaagcttggataggagac tttgcaatgccctccacggtgtggctgacaggcttcttcaacccccagtccttcctgacc gccatcatgcagtccacggcccgtaagaacgagtggcccctggacaagatggccctgcaa tgtgatgtgaccaagaagaacagggaggacttcaagagccctcctcgggaaggggcctac atccatggcctcttcatggaaggcgcttgctgggacatacaggctgggatcattacagac gcaaagctgaaggatctgacaccgcccatgcctgtgatgttcatcaaagccattcctgca gataagcaggaccaccgcagtgtctatccttgtcctgtgtacaagacttgtcagcgggga cccacctacgtgtggactttcaacctgaagactaaggagaaaccatcgaagtgggtgcta gctggagttgctttgcttctccagacttag

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