Canis lupus familiaris (dog): 490682
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Entry
490682 CDS
T01007
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa01522
Endocrine resistance
cfa04010
MAPK signaling pathway
cfa04012
ErbB signaling pathway
cfa04014
Ras signaling pathway
cfa04062
Chemokine signaling pathway
cfa04068
FoxO signaling pathway
cfa04072
Phospholipase D signaling pathway
cfa04150
mTOR signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04510
Focal adhesion
cfa04540
Gap junction
cfa04630
JAK-STAT signaling pathway
cfa04650
Natural killer cell mediated cytotoxicity
cfa04660
T cell receptor signaling pathway
cfa04662
B cell receptor signaling pathway
cfa04664
Fc epsilon RI signaling pathway
cfa04714
Thermogenesis
cfa04722
Neurotrophin signaling pathway
cfa04810
Regulation of actin cytoskeleton
cfa04910
Insulin signaling pathway
cfa04912
GnRH signaling pathway
cfa04915
Estrogen signaling pathway
cfa04917
Prolactin signaling pathway
cfa04926
Relaxin signaling pathway
cfa04935
Growth hormone synthesis, secretion and action
cfa05034
Alcoholism
cfa05160
Hepatitis C
cfa05161
Hepatitis B
cfa05163
Human cytomegalovirus infection
cfa05165
Human papillomavirus infection
cfa05200
Pathways in cancer
cfa05205
Proteoglycans in cancer
cfa05206
MicroRNAs in cancer
cfa05207
Chemical carcinogenesis - receptor activation
cfa05208
Chemical carcinogenesis - reactive oxygen species
cfa05210
Colorectal cancer
cfa05211
Renal cell carcinoma
cfa05213
Endometrial cancer
cfa05214
Glioma
cfa05215
Prostate cancer
cfa05220
Chronic myeloid leukemia
cfa05221
Acute myeloid leukemia
cfa05223
Non-small cell lung cancer
cfa05224
Breast cancer
cfa05225
Hepatocellular carcinoma
cfa05226
Gastric cancer
cfa05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
490682 (SOS2)
04012 ErbB signaling pathway
490682 (SOS2)
04014 Ras signaling pathway
490682 (SOS2)
04630 JAK-STAT signaling pathway
490682 (SOS2)
04068 FoxO signaling pathway
490682 (SOS2)
04072 Phospholipase D signaling pathway
490682 (SOS2)
04151 PI3K-Akt signaling pathway
490682 (SOS2)
04150 mTOR signaling pathway
490682 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
490682 (SOS2)
04540 Gap junction
490682 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
490682 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
490682 (SOS2)
04660 T cell receptor signaling pathway
490682 (SOS2)
04662 B cell receptor signaling pathway
490682 (SOS2)
04664 Fc epsilon RI signaling pathway
490682 (SOS2)
04062 Chemokine signaling pathway
490682 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
490682 (SOS2)
04912 GnRH signaling pathway
490682 (SOS2)
04915 Estrogen signaling pathway
490682 (SOS2)
04917 Prolactin signaling pathway
490682 (SOS2)
04926 Relaxin signaling pathway
490682 (SOS2)
04935 Growth hormone synthesis, secretion and action
490682 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
490682 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
490682 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
490682 (SOS2)
05206 MicroRNAs in cancer
490682 (SOS2)
05205 Proteoglycans in cancer
490682 (SOS2)
05207 Chemical carcinogenesis - receptor activation
490682 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
490682 (SOS2)
05231 Choline metabolism in cancer
490682 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
490682 (SOS2)
05225 Hepatocellular carcinoma
490682 (SOS2)
05226 Gastric cancer
490682 (SOS2)
05214 Glioma
490682 (SOS2)
05221 Acute myeloid leukemia
490682 (SOS2)
05220 Chronic myeloid leukemia
490682 (SOS2)
05211 Renal cell carcinoma
490682 (SOS2)
05215 Prostate cancer
490682 (SOS2)
05213 Endometrial cancer
490682 (SOS2)
05224 Breast cancer
490682 (SOS2)
05223 Non-small cell lung cancer
490682 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
490682 (SOS2)
05160 Hepatitis C
490682 (SOS2)
05163 Human cytomegalovirus infection
490682 (SOS2)
05165 Human papillomavirus infection
490682 (SOS2)
09165 Substance dependence
05034 Alcoholism
490682 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
490682 (SOS2)
01522 Endocrine resistance
490682 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
IQ_SEC7_PH
PH_13
Motif
Other DBs
NCBI-GeneID:
490682
NCBI-ProteinID:
XP_038442612
Ensembl:
ENSCAFG00000014275
VGNC:
46666
UniProt:
A0A8C0Q2P9
A0A8I3MQH2
LinkDB
All DBs
Position
8:complement(26390439..26470730)
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQLYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVCLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRNLFKPSDI
DRIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSNAEYRLKEKFIMRKTQICDKEDTCECKHAFELISKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPMPLEREPYKISFSRIAETDLESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYLLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPSY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagctgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgctggtctcggccctgcggaaggttcaggagcaagtacatcctaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactatcatgtatccctgtatattgtggctgtactagagtatatctcagctgat
attttgaagttggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtatcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttgtctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaaggcaatatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcctttctttcggacagaaatctgtttaaaccttctgatatt
gacagaattttcagtaacatttcagatatacacgaattgactgtgaaacttctaggtttg
attgaagacacagtggaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaggagcaagcatttgatccttatgaaacattatcacaggacatt
ctttctccaaaatttaatgaacatttcagtaagctgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctagtgcctgtttatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattacagctcttatgaat
ctccagggtagcatggaccgaatttataagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcatctagctattaaaaaaatg
aatgaaattcagaaaaacatagatgggtgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggtccattgacacgaattggtgctaaacatgaacgacatattttt
ctctttgatggcttaatgattagctgtaagcccaatcatagccagtcacgccttccaggt
tacagtaatgcagaatacagattaaaagaaaaatttatcatgaggaagacacagatatgt
gataaagaagatacttgtgagtgcaaacacgcttttgagttgatatccaaggatgaaaac
agcataatatttgctgctaaatcggctgaagagaaaaataattggatggccgcacttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcaaccattgagattaccaagtcctgaagtatatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaattcccattattaaa
ggaggaactgtggtgaaattaattgaaagattaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaatcccagagccggaacctactgaagcagataaattggct
gtagagaaaggcgaacagccaatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggatcttaaatgtatttcggcactgggttgaacaccacttttat
gactttgaaagggatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
ggaaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacactgcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagtccaaccttct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacgaatctcaccctttggtttgaaaagtgcattgtggaagca
gaaaattttgaagaacgggtggcaatactaagcagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtatca
gtgtacagactagaccatacttttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaaaactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggaaatgcttctgaa
aaggagtttacagattatttgttcaacaagtcactagaaattgagccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaatacggccg
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaatgccgttagaa
agagaaccatataaaataagctttagtcggattgctgaaactgatcttgaatcaactgtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggcagcaatagcatctttgctcca
gtcctcttgccgcattcaaagtctttcttcagttcatgtggtagtttacataaactaagt
gaagagccactgattcctcctcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatacgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaaccgagagttcctgctcctactggtgcatttgatgggcctctg
catagtccacctccaccgccaccaagagatcctcttcctgatacccctccgccagttccc
cttcgtcctccagaacactttataaactgtccatttaatcttcagccacctccactagga
catctgcacagagatccagactggttcagagacgttagtacctgcccaaattcgccaaat
actcctcccagcacgccctctccaagagtaccacgtcgatgctacctgctcagttctagt
cacaacaaccttgctcatcctcaagctccccctgtgccaccgaggcagaactcaagcccg
cacctaccaaaactgccaccaaagacttataaacgggagctttcacaccccccgtcatac
agactgcctttactagaaaatgcagaaactcctcaatga
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integrated database retrieval system
