Canis lupus familiaris (dog): 491166
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Entry
491166 CDS
T01007
Symbol
SLC46A1
Name
(RefSeq) proton-coupled folate transporter
KO
K14613
MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01523
Antifolate resistance
cfa04977
Vitamin digestion and absorption
cfa04978
Mineral absorption
cfa04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
491166 (SLC46A1)
04981 Folate transport and metabolism
491166 (SLC46A1)
04978 Mineral absorption
491166 (SLC46A1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
491166 (SLC46A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
cfa02000
]
491166 (SLC46A1)
Transporters [BR:
cfa02000
]
Solute carrier family (SLC)
SLC46: Folate transporter
491166 (SLC46A1)
Major facilitator superfamily (MFS)
Organic acid transporters
Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:
2.A.1.50
]
491166 (SLC46A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MFS_1
Sugar_tr
Motif
Other DBs
NCBI-GeneID:
491166
NCBI-ProteinID:
XP_003435354
Ensembl:
ENSCAFG00000018682
VGNC:
46426
UniProt:
A0A8C0Z2T9
A0A8I3N1L5
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Position
9:complement(41795562..41807087)
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AA seq
459 aa
AA seq
DB search
MEGRPSPPGEARVRRSAAALCRGPVEPLVFLANFALVLQGPLTTQYLWHRFSAELGYNGT
RDRGSCSNHSADPVMKEVETLTSHWTLYMNLGGFLVGLFSSTLLGAWSDCVGRRPLLVLA
SLGLLLQAVVSIFVVQLQLHVGYFVLGRILCALLGDFNGLLAASFASVADVSSNRSRTLR
MALLEACIGVAGMLASLLGGHWLRAQGYANPFWLALAVLIVMTFYAALCFGETVKEPTPA
RLFTLRHHRSIVWLYMTPAPEKSRKHLALYSLAIFMVITVHFGAQDILTLYELSKPLCWD
SRLVGYGSAAQHLPYLTSLVGLRLLQHCLADTWVAEIGLAFNILGMVVFAFATITPLMFT
GYGLLFLSLVTTPIIRAKLSKLVGKSEQGALFSSVACINSLAMLMASGIFNSLYPATLNF
MKGFPFLLGAGLLFIPAILIGVLEKANPHPEFQQFPQSP
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggaggggcgcccgagccccccgggcgaggcccgcgtccgccgctcggctgccgcgctg
tgccgcggccccgtggagcccctcgtcttcctggccaacttcgctttggtcctgcagggc
ccgctcaccacgcaatacttgtggcaccgcttcagtgccgagctcggctacaatggcacc
cgcgacaggggcagctgcagcaaccacagcgccgacccggtcatgaaggaagtggagacc
cttacctcccactggaccctctacatgaacctgggcggcttcctggtggggctcttctca
tccaccctgctgggtgcctggagtgactgcgtgggccgccgccccctcctggtgctggcc
tccctgggcctgttgctacaggcagtggtgtccatcttcgtcgtccagctgcagctccac
gtcggctacttcgtgctgggccgcatcctttgtgctctccttggggacttcaatggcctt
ctggcagcaagctttgcctctgtggcagatgtcagctccaaccgcagccgcaccttgcga
atggccctgctggaagcatgcatcggggtggcagggatgctggcaagcctcctggggggc
cactggctccgggcccagggttatgccaatcccttctggctggccttggccgtgttgata
gtcatgactttctatgcagcattatgctttggtgagacagtgaaggagccgacacctgcc
cggctcttcacgctccgtcaccaccgatccattgtctggctatacatgactccggcccca
gagaagtccaggaagcatttagccctgtattcactggccatcttcatggtaatcactgtg
cactttggggctcaggacatcctgaccctctatgagctgagcaaacccctctgctgggac
tccaggctggtcggctatggttcagcagctcagcacctcccgtacctcaccagcctagtg
ggcctgcggcttttgcagcactgcctggctgatacctgggtggccgagattggcctggcc
ttcaacattctggggatggtggtctttgcattcgctaccatcacacctctcatgtttaca
gggtatgggcttctgttcctgtcattagtcactacacccatcatccgggccaagctctcc
aagctggtgggcaagtcagagcagggtgctcttttttcttcggtggcctgcatcaatagc
ttggccatgctgatggcttctggcatcttcaactcactctacccagccaccttgaacttc
atgaaggggttccccttcctcctgggagctggcctcctcttcatcccggccattctgatt
ggggtgctggaaaaggctaatcctcatcccgaattccagcagtttcctcagagcccctga
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