Canis lupus familiaris (dog): 491498
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Entry
491498 CDS
T01007
Symbol
ALAS2
Name
(RefSeq) 5-aminolevulinate synthase, erythroid-specific, mitochondrial
KO
K00643
5-aminolevulinate synthase [EC:
2.3.1.37
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00260
Glycine, serine and threonine metabolism
cfa00860
Porphyrin metabolism
cfa01100
Metabolic pathways
cfa01240
Biosynthesis of cofactors
Module
cfa_M00868
Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
491498 (ALAS2)
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
491498 (ALAS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
cfa01007
]
491498 (ALAS2)
Enzymes [BR:
cfa01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.37 5-aminolevulinate synthase
491498 (ALAS2)
Amino acid related enzymes [BR:
cfa01007
]
Aminotransferase (transaminase)
Class II
491498 (ALAS2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aminotran_1_2
Preseq_ALAS
Cys_Met_Meta_PP
Aminotran_5
DegT_DnrJ_EryC1
Beta_elim_lyase
Motif
Other DBs
NCBI-GeneID:
491498
NCBI-ProteinID:
XP_038320456
Ensembl:
ENSCAFG00000014308
VGNC:
37777
UniProt:
A0A8C0TMN6
A0A8I3QB56
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Position
X:complement(38039113..38065286)
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AA seq
587 aa
AA seq
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MVVVAMLLQCCPVLARDHIGLLGKIIKTHQFLFGIGRCPILATQRPTFSQIHLKATKAGG
DSPPWAKSPCPFMLSELQDGKSKIVQKAAPEVQEDVKTFKTDLPRSPASTSLRKPFSNPQ
ELELISEKVTHLVQNNMIGNHVFGYDQFFRHKIMEKKQDHTYRVFKTVNRWADAYPFAQH
FSEASMASKDVSVWCSNDYLGMSRHPRVLQATQETLQRHGAGAGGTRNISGTSKFHVELE
QELAELHQKDAALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF
VFRHNDPDHLKKLLKESNTRTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVH
AVGLYGPQGAGIGERDGVMHKIDIVSGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV
GDAALNSKICDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVQKLLVAW
TEVGLPLQDVSMAACNFCHRPVHFELMSEWERSYFGNMGPQYVTTYA
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atggtagtagtagctatgttgctacagtgctgtcctgtgcttgcccgggaccatataggc
ctcctgggcaagatcattaagactcatcagttcctgtttggtattggacgctgtcctatc
cttgccacccaaagaccaaccttttctcaaatccaccttaaggcaaccaaggctggagga
gactctccaccttgggccaaaagcccctgtccctttatgctgtcagaactccaggatggg
aagagcaagattgtgcagaaggcagctccagaagtccaggaggatgtgaagactttcaag
acagacctgcccagatccccggcctcaaccagcctgagaaagccattctccaatccccag
gagctagagctaatttcagagaaggtcacacacctggttcagaacaacatgattggaaac
catgtttttggttatgaccagtttttcaggcacaagatcatggagaagaaacaggaccat
acctaccgtgtgttcaagactgtaaatcgctgggctgatgcatacccttttgcccaacac
ttctctgaggcatctatggcctcaaaggacgtgtcagtctggtgcagtaatgactatcta
ggcatgagccggcaccctcgggtcttgcaagctacacaggagaccctgcagcgtcatgga
gctggagctggtggtacccgcaatatttcaggtaccagtaagtttcatgtggagctggag
caggagctggctgagctgcaccaaaaagatgcagccctgcttttttcttcctgctttgtg
gcgaatgactctactctcttcactttggcaaagatcctgccaggttgtgagatttactca
gatgcagggaatcatgcttcaatgatccaaggtattcgcaacagtggagcagcgaagttt
gtcttcaggcacaatgaccctgaccacctgaagaaacttctaaaggaatccaatactagg
acacccaaaattgtggcctttgagactgttcactccatggatggtgccatctgtcccctt
gaggagttgtgtgatgtggcccatcagtatggggctctgactttcgtggatgaggttcat
gctgtagggctatatggaccccagggtgctgggattggggagcgtgatggagttatgcac
aagattgacattgtctctggaactcttggtaaggcctttggctgtgtgggtggctacatc
gccagcacccgtgacttggtggacatggtgcgctcctatgctgctggcttcatctttacc
acttcactgcctcccatggtgctctctggggctttagaatctgtgcggctgctcaaggga
gaggaaggccaagccctgaggcgagcccaccagcgcaatgtcaagcacatgcgccagcta
ctaatggacaggggccttcctgtcattccctgccccagccacatcatccccatccgggtg
ggtgatgcagcactgaacagcaagatctgtgatctcctgctctccaagcatggtatctat
gtgcaggccatcaactacccaactgtcccccgaggtgaagagctgctgcgtctggcaccc
tcccctcaccacagccctcagatgatggaagactttgtgcagaagctgctggtagcctgg
actgaggtggggctgcccctccaggatgtgtctatggctgcctgcaatttttgtcaccgg
cctgtgcactttgagctcatgagtgaatgggaacgttcctactttgggaacatggggccc
cagtatgtcaccacctatgcctga
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