Canis lupus familiaris (dog): 492302
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Entry
492302 CDS
T01007
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa02010
ABC transporters
cfa04024
cAMP signaling pathway
cfa04152
AMPK signaling pathway
cfa04530
Tight junction
cfa04971
Gastric acid secretion
cfa04972
Pancreatic secretion
cfa04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
492302 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
492302 (CFTR)
04152 AMPK signaling pathway
492302 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
492302 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
492302 (CFTR)
04972 Pancreatic secretion
492302 (CFTR)
04976 Bile secretion
492302 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
cfa02000
]
492302 (CFTR)
Enzymes [BR:
cfa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
492302 (CFTR)
Transporters [BR:
cfa02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
492302 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
AAA_21
SMC_N
AAA_29
T2SSE
AAA_16
DUF87
RsgA_GTPase
MMR_HSR1
nSTAND3
MeaB
Zeta_toxin
NTPase_1
Intein_splicing
Motif
Other DBs
NCBI-GeneID:
492302
NCBI-ProteinID:
NP_001007144
Ensembl:
ENSCAFG00000003429
VGNC:
39180
UniProt:
Q5U820
LinkDB
All DBs
Position
14:55685755..55848173
Genome browser
AA seq
1483 aa
AA seq
DB search
MQRSPLEKASVLSKLFFSWTRPILIKGYRQRLELSDIYQVPSTDSADHLSEKLEREWDRE
LASKKNPKLINALRRCFFWRFAFYGILLYLGEVTKAVQPLLLGRIIASYDPDNKQERSIA
IYLAIGLCLLFIMRPLLLHPAIFGLHHIGMQIRIAMFSLIYKKTLKLSSRVLDKISIGQL
VSLLSNNLNKFDEGLALAHFVWIAPLQVTLLMGLLWDLLQASAFCGLAFLIVLALVQAGL
GRMIMKYRDQRAGKINERLVITSEVIENIQSVKAYCWEEAMEKIIENIRQTELKLTRKAA
HVRYFNSSAFFFSGFFVVSLSVLPYALIKTIILRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVMMENVTAFWEEGFGELLEKAKENSNDRK
ISNGDNSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEG
KIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV
LGEGGVTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKVLILHEGSCYFYGTFSELQSLRPDFSSKLMGYDSFDQFSPERRNS
IITETLRRFSLEGDAAVPWNETKKQSFKQTGEFGEKRKNSILNPINSIRKFSIVQKTPLP
MNGIEGESEVPVERRLSLFPDCEQGEAILPRSNMINTGPTLRRQRRQSVLNLMTRSSVNQ
GQSIHRRTTASTRKMSLAPQANLTEMDIYSRRLSQDSGLEISEEINEEDLKECFFDDVES
IPPVTTWNTYLRYITVHKNLIFVLIWCLVIFLAEVAVSLVVLWILRNLSSQDKGNSTQSV
NSSYAVIFTSTSAYYIFYIYVGVADTLLALGLFRGLPLVHTLITASKILHHKMLHSVLQA
PMSTLNTLKAGGILNRFPKDIAILDDLLPLTIFDFIQLLLIVIGAVAVVSVLQPYIFLAT
VPVIAAFIILRAYFLHTSQQLKQLESEGRSPIFTHLLTSLKGLWTLRAFGRQPYFETLFH
KALNLHTANWFLYLSTLRWFQMRMEIIFVIFFIAVTFISILTTGEGEGTVGIILTLAMNI
MGTLQWAVNPSIEVDSLMRSVSRVFKFIDMPTEESKPPTKSFKPSKDAQLSKVTITENRH
VREDDIWPSGGQMTVKDLTAKYIDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAL
LRLVNTEGEIQIDGVSWDSIPLQEWRRAFGVIPQKVFIFSGTFRKNLDPYGQWNDQEIWK
VADEVGLRSVIEQFPGKLDFVLVDGGYVLSHGHKQLMCLARSVLRKAKILLLDEPSAHLD
PITYQIIRRTLKQAFADCTVILSEHRIEAMLECQRFLVIEDSRLRQFESIQRLLSERSAF
RQAIGPPERPGLLPHRLSSRQRSPSRIAALKEETEDEVQDTRL
NT seq
4452 nt
NT seq
+upstream
nt +downstream
nt
atgcagaggtcgcccctggaaaaggccagcgtcctctccaaacttttcttcagctggacc
agaccaattttgataaaaggctatagacaacgcctggaattatcagacatataccaagtc
ccttctactgattctgctgatcatctgtctgaaaaattggaaagagaatgggacagagag
ctggcatcaaagaagaaccccaaacttattaatgcccttcggcgatgctttttctggaga
tttgcgttctatggaatcttattatatttaggggaagtcaccaaagcagtccagcctctc
ttacttggaagaatcatagcttcctatgatccagataacaagcaggaacgctccattgca
atctacctagccattggcttatgccttctctttatcatgaggccgctgctcctgcaccca
gccatttttggccttcatcacattggaatgcagatcagaatagctatgtttagtttgatt
tataagaagactttaaagctgtcaagccgtgttctggataaaataagtattggacaactt
gttagtctcctttccaacaacctgaacaaattcgatgaaggacttgcactggcgcatttc
gtgtggattgctcctctacaagtgacgctcctgatggggctgctctgggatttgttacaa
gcctctgccttctgtggtcttgctttcctcatagtcctcgcccttgtccaagctggtttg
ggaagaatgataatgaagtacagagatcagagagctggaaagatcaatgaaagactcgtg
atcacctcagaagtgattgaaaatatccaatctgttaaggcatactgctgggaggaagca
atggaaaagataattgaaaacataagacaaacagagctgaaactgacccggaaggcagcc
catgtgagatacttcaatagctcagccttcttcttctcagggttctttgtggtgtcttta
tctgtgcttccctatgcactgatcaaaacaatcatccttcgcaaaatattcacaaccatc
tcattctgcatcgttttgcgcatggcagtcactcggcaatttccctgggctgtacaaaca
tggtatgactctcttggagcaataaacaaaatacaggatttcttacaaaagcaagagtat
aagacgttggaatataacttaacaactacggaagtaatgatggagaatgtaacagccttc
tgggaggagggatttggggaattacttgagaaagcaaaagaaaacagtaatgacagaaaa
atttccaatggggacaacagcctcttcttcagcaacttctcacttcttggtactcctgtc
ctaaaagacatcaatttcaagatagaaagaggacagttgttggcggttgctggatctact
ggagcaggcaagacttcactcctaatgatgattatgggagaactggagccttcagagggt
aaaattaagcacagtggaagaatttcattctgctctcagttttcttggattatgcctggc
accattaaagaaaacatcatctttggtgtttcctatgatgagtatagatataggagtgtc
atcaaagcatgccaactagaggaggacatttccaagtttgcagagaaggacaacatcgtt
cttggagaaggtggcgtcacgctgagcggagggcaaagagcaagaatttccctagcaaga
gcagtatataaagatgctgatttatatctcttagactctccttttggatacctggatgtt
ttaacagaaaaagaaatatttgaaagctgtgtctgtaaattgatggctaacaaaactagg
atcttggtcacttctaaaatggaacatttaaagaaagctgacaaagtcttaattttacat
gaaggtagctgctatttttatgggacattttctgaattacaaagtctccggcccgacttc
agctcgaagctcatgggctatgattcttttgaccagttcagtccagaaagaagaaactcc
atcatcactgagactttacggcgtttctccttagaaggagatgcggccgtgccctggaat
gaaacaaaaaagcaatcttttaaacagactggagagtttggtgaaaaaaggaagaactct
attcttaatccaatcaactccataagaaaattttcaattgtacaaaagaccccgttaccc
atgaatggcatcgaaggagagtctgaggtgccagtagagcgaaggctgtccttatttccc
gactgtgagcaaggagaggccatcctgcctcggagcaacatgatcaacactggccccacg
ctccggagacaacgaagacagtctgttctgaacctgatgacgcgctcctccgtgaaccaa
ggtcagagcattcaccgaaggacaacagcatccacgcgaaaaatgtcactggcccctcag
gcaaatctaactgaaatggatatatattccagacggttatctcaagacagtggcttggaa
ataagtgaagaaattaatgaagaggatttaaaggagtgcttttttgatgatgtcgagagc
ataccaccagtgactacatggaacacataccttcgatatattactgtccacaagaactta
atttttgtgctaatttggtgcttagttatttttctggctgaggtggctgtttcattggtt
gtattgtggatacttagaaacttgtcttctcaagacaaagggaatagcactcagagcgta
aacagcagttatgcagtgatcttcaccagtaccagcgcatattatattttctacatttat
gtgggagtagctgatactttgcttgctctgggactcttcagaggtttaccactggtgcat
actctaatcacagcgtcgaaaattttacaccacaaaatgttacattctgttcttcaggca
cctatgtcaaccctcaacacactgaaagcaggtgggattcttaatagattccccaaagat
atagcgattttggatgatcttctgccccttaccatatttgacttcatccagttgttatta
attgtgatcggagctgtggcggtggtgtcagttttacagccctacatcttcctagcgaca
gtgccagtgatagcggcctttattatcctgcgggcctacttcctccacacctcacagcaa
ctcaagcaactggaatctgaaggcaggagtccaattttcactcatcttcttacaagttta
aaaggactgtggacacttcgggcctttggacgccagccttactttgagactttgtttcac
aaagctctgaacttacatactgccaactggttcttgtacctgtcaacgctgcgctggttc
caaatgagaatggaaattatttttgtcatattcttcattgctgttaccttcatctccatt
ttaacaacaggtgaaggagaaggaacagttggtattattctaacattagccatgaatatc
atgggtacgttgcagtgggctgtaaaccccagcatagaggtggacagcttgatgcgatcg
gtgagccgagtcttcaagtttattgacatgcctacagaagaaagtaaaccacctaccaag
tcattcaaaccatccaaggatgcccaactctcaaaagttacgattactgagaatcggcat
gtgagggaagatgatatctggccctcagggggccaaatgactgtcaaagacctcacagca
aagtatatagatggtgggaatgccatattagagaacatttccttctcaataagtcctggc
cagagggtgggcctcttgggaagaactggatcagggaaaagtactttgttatctgctctt
ttgagactggtgaacactgagggagaaatccaaatagatggcgtgtcttgggactcaatc
cctttgcaagaatggaggagagcctttggggtgatcccacagaaagtatttatattctct
ggaacatttagaaaaaacttggatccctatggacagtggaatgatcaagaaatatggaaa
gttgcggatgaggttggactcagatctgtgatagagcagtttcctgggaagctcgatttc
gtcctggtggatgggggttacgtcctaagccatggccacaagcagttgatgtgcttggcc
agatctgtcctcaggaaggcgaaaatcctgctgctcgatgaacccagtgctcatttggat
ccaataacataccaaatcattcgaagaaccctaaagcaagcgtttgcagattgcacagtg
atcctttctgaacacaggatagaagcgatgttggaatgtcaacgattcttggtcatcgag
gacagcaggctgcggcagttcgagtccatccagaggctgctgagcgagaggagcgccttc
cggcaggccatcgggccccccgagcggcccggcctcctcccgcaccggctctccagccgg
cagaggtccccttccaggatcgcggccctgaaggaggagacggaagacgaggtgcaggac
acaaggctttag
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integrated database retrieval system
