Canis lupus familiaris (dog): 494000
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Entry
494000 CDS
T01007
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor
KO
K03871
von Hippel-Lindau disease tumor supressor
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04066
HIF-1 signaling pathway
cfa04120
Ubiquitin mediated proteolysis
cfa05200
Pathways in cancer
cfa05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
494000 (VHL)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
494000 (VHL)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
494000 (VHL)
09162 Cancer: specific types
05211 Renal cell carcinoma
494000 (VHL)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
cfa04121
]
494000 (VHL)
Ubiquitin system [BR:
cfa04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
Cul2 complex
Target recognizing subunit
494000 (VHL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
VHL
VHL_C
Arm_vescicular
Motif
Other DBs
NCBI-GeneID:
494000
NCBI-ProteinID:
NP_001008552
Ensembl:
ENSCAFG00000044690
UniProt:
Q5Q9Z2
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Position
20:complement(8240602..8245270)
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AA seq
219 aa
AA seq
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MPRKAGSVEEAEAGAEEVGAEEVGPEESGGEESGAEESGPEESDPEEPGAAAEMEAGQPR
PVLRSVNSCEPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTYDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVRKDLERLAQEHIENQRMEGETEDFN
NT seq
660 nt
NT seq
+upstream
nt +downstream
nt
atgccccggaaggcagggagcgtggaggaggccgaggcgggcgccgaggaggtgggcgcc
gaggaggtgggccctgaagagtccggcggggaggagtctggcgcggaggagtccggcccg
gaagagtctgacccggaggagccgggcgctgcggcggagatggaggccgggcagccgcgg
ccggtgctgcgctcggtgaactcgtgcgagccgtcccaggtcatcttctgcaaccgcagc
ccgcgcgtcgtgctgccggtgtggctcaacttcgacggcgagccgcagccctacccgacg
ctgccgccgggcacgggccgccgcatccacagctaccgaggtcacctttggctcttccga
gatgccgggacatatgatgggcttctggttaaccaaactgaactatttgtgccatctctc
aatgttgatggacagccaatttttgccaacatcacactgccagtgtatactctgaaagag
cggtgcctccaggttgtccgaagcctagtcaagcctgagaattataggagactggacatc
gtgagatccctctatgaagatctggaagaccacccgaatgtaaggaaagacctggagcgg
ctggcacaggagcatattgaaaatcagcgaatggaaggggagactgaggattttaattga
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