Canis lupus familiaris (dog): 608821
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Entry
608821 CDS
T01007
Symbol
SMURF1
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF1 isoform X1
KO
K04678
E3 ubiquitin ligase SMURF1/2 [EC:
2.3.2.26
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04120
Ubiquitin mediated proteolysis
cfa04137
Mitophagy - animal
cfa04144
Endocytosis
cfa04340
Hedgehog signaling pathway
cfa04350
TGF-beta signaling pathway
cfa04520
Adherens junction
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
608821 (SMURF1)
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
608821 (SMURF1)
04350 TGF-beta signaling pathway
608821 (SMURF1)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
608821 (SMURF1)
04137 Mitophagy - animal
608821 (SMURF1)
09144 Cellular community - eukaryotes
04520 Adherens junction
608821 (SMURF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cfa04131
]
608821 (SMURF1)
04121 Ubiquitin system [BR:
cfa04121
]
608821 (SMURF1)
03029 Mitochondrial biogenesis [BR:
cfa03029
]
608821 (SMURF1)
Enzymes [BR:
cfa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
608821 (SMURF1)
Membrane trafficking [BR:
cfa04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
608821 (SMURF1)
Autophagy
Mitophagy
Other mitophagy associated proteins
608821 (SMURF1)
Ubiquitin system [BR:
cfa04121
]
Ubiquitin ligases (E3)
HECT type E3
608821 (SMURF1)
Mitochondrial biogenesis [BR:
cfa03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
608821 (SMURF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
DUF7350
Motif
Other DBs
NCBI-GeneID:
608821
NCBI-ProteinID:
XP_038395423
Ensembl:
ENSCAFG00000015133
VGNC:
46580
UniProt:
A0A8C0NJG6
A0A8I3N723
LinkDB
All DBs
Position
6:12010745..12124123
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AA seq
731 aa
AA seq
DB search
MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP
KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCK
LNPSDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLVENEGTVYEDSGPGRPLSCFMEEPA
PYTDSTGAAAGGGDCRFVESPSQDQRLQAQRLRNPEVRGSLQTPQNRPHGHQSPELPEGY
EQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVD
HNNRTTQFTDPRLHHIMNHQCQLKEPSQPLPLPSEGSVEDEELPAQRYERDLVQKLKVLR
HELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVARE
WLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYI
NGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRIL
QHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQK
ELELIIGGLDKIDVSDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTR
VPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLT
AVEETCGFAVE
NT seq
2196 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaaccccgggacgcgcaggaacggctccagcattaagatccgtctgacagtatta
tgtgccaagaaccttgcaaagaaagacttcttcagactccctgacccctttgcaaagatt
gtggtggatggatctgggcagtgccactcaacggacactgtgaaaaacacgttggaccca
aaatggaaccagcactacgatctgtatgttgggaaaactgattctataaccatcagcgtg
tggaaccacaagaagatccacaagaagcagggagctggctttctgggctgtgtgcgccta
ctctccaatgccatcagcagattaaaagatactggataccagcgtttggatctatgcaaa
ctaaatccctcagatactgatgcagttcgtggccaaatagtggtcagtttacagacacga
gacaggataggcactggaggctctgtggtagactgcagaggactggtagagaatgaagga
actgtgtatgaagattcagggcctgggaggccactcagctgcttcatggaggagccagcc
ccctacactgacagtacaggtgctgctgcagggggaggggactgtaggttcgtggaatct
ccgagtcaagatcaaagactccaggcacagcggctccgaaatcctgaggtccgggggtca
ctacaaacgccccagaaccgaccccacggccatcagtcaccagaactgcctgaaggctat
gagcaaagaacaacggtgcaggggcaagtttactttttgcacacgcagactggagttagc
acgtggcatgaccccaggataccaagagaccttaacagtgtgaattgtgatgaacttgga
ccactgccaccaggttgggaagtcagaagtacagtttcggggagaatatattttgtagat
cataataaccggacaacccagtttacagacccaagattacatcacatcatgaatcaccag
tgccaactaaaggagcccagccagccactgcctttgcccagcgagggctccgtggaagat
gaggagctgcctgcccagagatatgaacgagatttagtgcagaagctgaaggtgctcaga
catgagctttcacttcagcagccccaagccggccattgccgcatcgaagtatccagagaa
gaaatatttgaggaatcttaccgccagatcatgaagatgcggcctaaggatttgaagaag
cggctgatggtgaagttccggggagaagaaggtttggattatggcggagtggcaagggag
tggctttatttattatgccatgaaatgttgaatccatattatggactcttccaatattct
acggacaacatttacatgttgcaaatcaacccggattcttcaattaatccagaccacctg
tcttatttccattttgtgggccggatcatgggtctcgctgtgttccacgggcactacata
aacgggggcttcacggttcccttctataagcagctcctggggaagcccatccagctctcg
gatttggagtcggtggacccagaattacacaagagcttggtgtggattctagagaatgat
atcacccccgtgctagaccacactttctgtgtggaacacaatgctttcgggaggattctt
cagcatgaactaaaacccaatggccgaaatgttcctgtcacagaggagaacaagaaagaa
tatgtccggttgtatgtgaattggaggttcatgagggggatcgaagcccagttcctcgct
ctacagaaagggtttaatgaacttattcctcaacacttactgaagccttttgaccagaag
gaactagagctcatcataggcggcctggataaaatagatgtgagcgactggaagtccaac
actcggctgaagcactgcgtggccgacagcaacatcgtcaggtggttctggcaggccgtg
gagaccttcgatgaggagaggagggccaggctcctgcagttcgtgactgggtccactcgg
gtccctctccaggggttcaaggctttgcaaggttctacaggcgccgcagggccccggctc
ttcaccatccacctgatcgatgccaacacagacaaccttccaaaggcccacacctgcttt
aatcggattgacattccaccttatgaatcatatgagaagctctatgagaagctgctgaca
gccgtggaggagacttgtgggtttgctgtggagtga
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