KEGG   Canis lupus familiaris (dog): 609050
Entry
609050            CDS       T01007                                 
Symbol
MGST3
Name
(RefSeq) microsomal glutathione S-transferase 3
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00480  Glutathione metabolism
cfa00980  Metabolism of xenobiotics by cytochrome P450
cfa00982  Drug metabolism - cytochrome P450
cfa00983  Drug metabolism - other enzymes
cfa01100  Metabolic pathways
cfa01524  Platinum drug resistance
cfa05200  Pathways in cancer
cfa05204  Chemical carcinogenesis - DNA adducts
cfa05207  Chemical carcinogenesis - receptor activation
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05225  Hepatocellular carcinoma
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    609050 (MGST3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    609050 (MGST3)
   00982 Drug metabolism - cytochrome P450
    609050 (MGST3)
   00983 Drug metabolism - other enzymes
    609050 (MGST3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    609050 (MGST3)
   05204 Chemical carcinogenesis - DNA adducts
    609050 (MGST3)
   05207 Chemical carcinogenesis - receptor activation
    609050 (MGST3)
   05208 Chemical carcinogenesis - reactive oxygen species
    609050 (MGST3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    609050 (MGST3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    609050 (MGST3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    609050 (MGST3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:cfa02000]
    609050 (MGST3)
Enzymes [BR:cfa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     609050 (MGST3)
Transporters [BR:cfa02000]
 Other transporters
  Pores ion channels [TC:1]
   609050 (MGST3)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 609050
NCBI-ProteinID: NP_001239339
Ensembl: ENSCAFG00000013353
VGNC: 53121
UniProt: A0A8C0T101 F1PCR0
LinkDB
Position
38:complement(17726881..17748346)
AA seq 152 aa
MAVLSKEYGFVVLTGAASFIMVAHLAINVSKARKKYKVEYPTMYSTDPENGHLFNCIQRA
HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSL
ALIGLMGTTVFSAFQHLGWVKTGLGGGSKCCH
NT seq 459 nt   +upstreamnt  +downstreamnt
atggctgtcctctcgaaggaatatggtttcgtggttctaaccggtgctgctagcttcata
atggtagctcatctagccatcaatgtttccaaggcccgaaagaagtacaaagtggagtat
cccaccatgtacagcacggaccccgaaaacgggcacctgttcaactgcattcagcgcgcc
caccagaacacgttggaagtgtatcctccgttcttatttttcctagcggttggaggtgtt
taccacccgcgtatagcttctggcctgggcttggcctggattgttggacgagttctttac
gcctatggttattacacaggagagcccagcaagcggagtcggggagccctgggctcctta
gccctcatcggcctgatgggcaccacggtgttctctgccttccagcatcttggttgggtt
aaaactggcttgggcggtggatccaaatgctgccattga

DBGET integrated database retrieval system