Canis lupus familiaris (dog): 609574
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Entry
609574 CDS
T01007
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00230
Purine metabolism
cfa01100
Metabolic pathways
cfa04022
cGMP-PKG signaling pathway
cfa04740
Olfactory transduction
cfa04925
Aldosterone synthesis and secretion
cfa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
609574 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
609574 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
609574 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
609574 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
609574 (PDE2A)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
609574 (PDE2A)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
DUF3887
Motif
Other DBs
NCBI-GeneID:
609574
NCBI-ProteinID:
XP_038312212
Ensembl:
ENSCAFG00000005698
VGNC:
44351
LinkDB
All DBs
Position
21:25314283..25406213
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AA seq
1044 aa
AA seq
DB search
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPPPPPQPCADSLQPARTSLHR
SQCPQGIETPDWRPLCLPVRDPWICFVQLPNHEDRVRGAAEEGVEAGEAPGDQKDWDSCD
EGDAGDVLGKKAEASRRMWAMRMEVTTDPAMWTRWLKDALLSLGAVIHIAGFRRAVKEAL
SAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKVREAVVSRKRLGCNGLGPSNLPGKP
LARLVAPLAPDSQVLVMPLVDKEAGAVAAVILVHCGQLNDSEEWSLQAVEKHSLVALRRV
QALQQRGPGAAPGAVPNPPAGGVAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETQ
ASRCCLLLVSEDNLQLSCKVIGDKVLEEETSFPLTTGRLGHVVEDKKSIQLKDLTSEDVQ
QLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDLFTEQDERVIQHCFHYTSTVL
TSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ
NELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGF
RTRNILCFPIKNESQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKV
NEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSM
AILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLEL
TNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAI
LNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRTNKQHHS
LLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPE
LQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLD
EEYEVPELDGTRAPVNGCCSLDAE
NT seq
3135 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcatgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgagccgcggggccagcaggtcttcctcaagccggacgagccgccgccgccgccg
ccgccgccgccgcagccatgcgccgacagcctgcagccagcccggacctccttgcacagg
agccagtgcccccagggaatagagacgcccgactggaggccactgtgtctgcctgtcaga
gacccctggatttgcttcgtccagcttcccaaccatgaagaccgtgtgaggggtgcagct
gaggaaggagttgaggctggagaggcaccaggtgatcagaaggactgggacagctgtgat
gagggggacgctggtgatgtgctggggaagaaggctgaggcatcgaggagaatgtgggcc
atgaggatggaggtcactactgaccctgccatgtggacgaggtggttgaaggatgctttg
ttgagcctgggtgctgtcatccacattgcaggcttccggcgggctgtcaaggaggccctc
tcagccgtgctccccaaagtggagaccgtctacacctacctactggatggggagtcccgg
ctggtgtgtgaggaccccccccacgagctgccccaggaagggaaagtccgagaggctgtg
gtctcccggaagcggctgggctgcaatggactgggcccctcaaatctgccagggaagccc
ttggccaggctggtggctccactggctcctgacagccaagtgctggtcatgccgctggtg
gacaaggaggctggggctgtggcggccgtcatcctggtgcactgtggccagctgaatgac
agtgaagagtggagcctgcaggcagttgagaagcatagcctggtggccctgcgaagggtg
caggccctgcagcagcgcgggcccggcgctgccccgggagcggtcccgaaccccccggcg
ggcggggtggcctacaccgaccgggaccggaagatcctgcagctgtgcggggaactctac
gacctggacgcctcttccctgcagctcaaagtcctccaatacctgcagcaggagacccag
gcctctcgatgctgcctcctgctggtgtccgaggacaatctccagctttcctgtaaggtc
atcggagacaaagtgctggaggaagaaaccagctttccgttgaccacaggacgcctgggc
catgtggtggaagataagaagtctatccagctgaaagatctcacctctgaggatgtgcaa
cagctgcagaacatgttgggctgtgagctgcaggccatgctctgcgtccctgtcatcagc
cgggctacagaccaggtggtggccttagcctgcgccttcaacaagctcggaggagacttg
ttcacggaacaggatgagcgagtgatccagcactgcttccactacacgagcacggtgctc
accagcaccctggccttccagaaagagcaaaagctcaagtgtgagtgccaggctcttctc
caagtggcaaagaacctcttcactcacctggatgatgtctctgtcctgctccaggagatc
attacagaggccagaaacctcagcaacgctgagatctgctccgtgttcctgctggatcag
aacgagctggtggccaaggtgttcgacgggggtgtggtggatgacgagagctacgagatc
cgcatccccgctgaccagggcattgcgggccacgtggcaactaccggccagatcctgaac
atcccggacgcgtacgcgcatccgctcttctaccgcggcgtggacgacagcaccggcttc
cgcacgcgcaacatcctctgcttccccatcaagaacgagagccaggaggtcattggtgtg
gccgagctggtgaacaagattaacggaccatggttcagcaagttcgacgaggacctggcg
accgccttctctatctactgtggcatcagcatagcccattccctcctctacaagaaagtg
aatgaggcccagtatcgcagccacctggccaacgagatgatgatgtaccacatgaaggtc
tctgatgatgaatataccaaactcctccatgatggaatccagcctgtggctgccattgac
tccaactttgccagtttcacctatacccctcgctctctgcccgaggatgacacttccatg
gccatcctgagcatgctgcaggacatgaatttcatcaataactacaaaatcgattgcccg
actctggcccggttctgtttgatggtgaagaagggctaccgggatcccccctaccacaac
tggatgcacgccttttccgtctcccacttctgctacctgctctataagaatctggagctc
accaactacctcgaggacatcgagatctttgccttgtttatttcctgcatgtgtcatgac
ctggaccacagaggcacaaacaactccttccaggtggcctcgaaatctgtgctggctgcg
ctctacagctccgagggctctgtcatggagaggcaccacttcgctcaggccatcgccatc
ctcaacacccacggttgcaacatctttgaccacttctcccggaaggactatcagcgtatg
ctggacctgatgcgggacatcatcttggccaccgacctggcccatcacctccgcatcttc
aaagacctccagaagatggctgaagtgggttatgaccgtaccaacaagcagcaccatagc
ctcctcctctgcctccttatgacctcctgtgacctctctgaccagaccaagggctggaag
acaacgaggaagattgcagagctgatctacaaagagttcttctcccagggagacttggag
aaggccatgggcaacaggccgatggagatgatggaccgggagaaggcctacatccctgag
ctgcagatcagctttatggagcacatcgcaatgcccatctacaagctgctccaggacctg
ttccccaaggcggcagagctgtatgaacgtgtggcctctaaccgtgagcactggaccaag
gtgtctcacaagttcaccatccgcggcctcccgagcaacaactcgctggacttcctggat
gaggagtacgaggtgcctgagctggatggcaccagagcccccgttaatggctgttgcagc
cttgacgctgaatga
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