KEGG   Canis lupus familiaris (dog): 610537
Entry
610537            CDS       T01007                                 
Symbol
AKR1A1
Name
(RefSeq) aldo-keto reductase family 1 member A1
  KO
K00002  alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00010  Glycolysis / Gluconeogenesis
cfa00040  Pentose and glucuronate interconversions
cfa00053  Ascorbate and aldarate metabolism
cfa00561  Glycerolipid metabolism
cfa00620  Pyruvate metabolism
cfa01100  Metabolic pathways
cfa01240  Biosynthesis of cofactors
cfa05208  Chemical carcinogenesis - reactive oxygen species
Module
cfa_M00014  Glucuronate pathway (uronate pathway)
cfa_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    610537 (AKR1A1)
   00040 Pentose and glucuronate interconversions
    610537 (AKR1A1)
   00053 Ascorbate and aldarate metabolism
    610537 (AKR1A1)
   00620 Pyruvate metabolism
    610537 (AKR1A1)
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    610537 (AKR1A1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    610537 (AKR1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    610537 (AKR1A1)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.2  alcohol dehydrogenase (NADP+)
     610537 (AKR1A1)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   610537 (AKR1A1)
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 610537
NCBI-ProteinID: NP_001239097
Ensembl: ENSCAFG00000004517
VGNC: 37768
LinkDB
Position
15:complement(14913465..14929729)
AA seq 325 aa
MAASCVLLHTGQKMPLIGLGTWKSDPGQVKAAIMYALSVGYRHIDCAAIYGNEAEIGEAL
KENVGPGKVVLREELFVTSKLWNTKHHPKDVEPALRKTLADLQLEYLDLYLMHWPYAFER
GDNPFPRNADGTIRYDSTHYKETWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRP
AVLQVECHPYLAQKELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFTFSPDEMKQLDALNKNWRYIV
PMLTVDGKRVPRDAGHPLYPFNDPY
NT seq 978 nt   +upstreamnt  +downstreamnt
atggcggcttcatgtgtcctcctgcacactgggcagaagatgcccctgattgggctgggc
acctggaagagtgatcctggccaggtaaaagcagctattatgtatgccctgagtgtaggc
taccgccacattgactgtgctgctatctacggcaatgaggctgagatcggggaggccctg
aaggagaatgtaggacctggcaaggtggtgcttcgagaggagctgtttgtgacttctaag
ctgtggaacactaaacaccaccccaaggatgtggagcctgccctccggaagacactggct
gacctccagctggagtatttggacctgtacctgatgcactggccttatgcctttgagcgg
ggagacaaccctttccctagaaatgccgatgggacaatccgctatgactctacccactac
aaggagacctggaaagctctggaggcactggtggctaagggactggtacgagcactgggc
ctgtccaatttcagcagtcggcagatcgatgatgtgctcagtgtggcctctgtacgccca
gctgtcctgcaggtggaatgtcacccatacttggctcagaaggagctgattgctcattgc
caagcacgtggcctggaggtgaccgcttatagccctctgggatcctctgatagagcttgg
cgtgatcctgatgagcctgtcctacttgaggagccggtagtcttggcactggctgaaaag
tatggccggtctccagctcagatcctgctcaggtggcaggtccagcggaaagtgatctgc
atccccaagagtatcacaccttcacgtattctccagaacatccaggtgtttgacttcacc
tttagcccagacgagatgaagcagctagatgccctgaataaaaattggcgatacattgtg
cccatgctcacagtggatgggaagagggtcccgagagatgcagggcatcctctgtacccc
tttaatgatccatactga

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