KEGG   Camelus ferus (Wild Bactrian camel): 102505131
Entry
102505131         CDS       T02979                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr04010  MAPK signaling pathway
cfr04020  Calcium signaling pathway
cfr04022  cGMP-PKG signaling pathway
cfr04114  Oocyte meiosis
cfr04218  Cellular senescence
cfr04310  Wnt signaling pathway
cfr04360  Axon guidance
cfr04370  VEGF signaling pathway
cfr04380  Osteoclast differentiation
cfr04625  C-type lectin receptor signaling pathway
cfr04650  Natural killer cell mediated cytotoxicity
cfr04658  Th1 and Th2 cell differentiation
cfr04659  Th17 cell differentiation
cfr04660  T cell receptor signaling pathway
cfr04662  B cell receptor signaling pathway
cfr04720  Long-term potentiation
cfr04724  Glutamatergic synapse
cfr04728  Dopaminergic synapse
cfr04921  Oxytocin signaling pathway
cfr04922  Glucagon signaling pathway
cfr04924  Renin secretion
cfr05010  Alzheimer disease
cfr05014  Amyotrophic lateral sclerosis
cfr05020  Prion disease
cfr05022  Pathways of neurodegeneration - multiple diseases
cfr05031  Amphetamine addiction
cfr05152  Tuberculosis
cfr05163  Human cytomegalovirus infection
cfr05166  Human T-cell leukemia virus 1 infection
cfr05167  Kaposi sarcoma-associated herpesvirus infection
cfr05170  Human immunodeficiency virus 1 infection
cfr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cfr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102505131 (PPP3CA)
   04310 Wnt signaling pathway
    102505131 (PPP3CA)
   04370 VEGF signaling pathway
    102505131 (PPP3CA)
   04020 Calcium signaling pathway
    102505131 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    102505131 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102505131 (PPP3CA)
   04218 Cellular senescence
    102505131 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102505131 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    102505131 (PPP3CA)
   04660 T cell receptor signaling pathway
    102505131 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    102505131 (PPP3CA)
   04659 Th17 cell differentiation
    102505131 (PPP3CA)
   04662 B cell receptor signaling pathway
    102505131 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    102505131 (PPP3CA)
   04921 Oxytocin signaling pathway
    102505131 (PPP3CA)
   04924 Renin secretion
    102505131 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    102505131 (PPP3CA)
   04728 Dopaminergic synapse
    102505131 (PPP3CA)
   04720 Long-term potentiation
    102505131 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    102505131 (PPP3CA)
   04380 Osteoclast differentiation
    102505131 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102505131 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102505131 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    102505131 (PPP3CA)
   05163 Human cytomegalovirus infection
    102505131 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102505131 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102505131 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102505131 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    102505131 (PPP3CA)
   05020 Prion disease
    102505131 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    102505131 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    102505131 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102505131 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:cfr01009]
    102505131 (PPP3CA)
Enzymes [BR:cfr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     102505131 (PPP3CA)
Protein phosphatases and associated proteins [BR:cfr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     102505131 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 102505131
NCBI-ProteinID: XP_032316574
UniProt: A0A8B8RHJ9
LinkDB
Position
2:complement(71001883..71289913)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgacggacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacagcaaaagaagtctttgataacgatgggaaa
cctcgagtggatatcctaaaggcacatctcatgaaggagggccggctggaagagagtgtt
gcattgagaataataacagagggggcttccattcttcgacaggaaaaaaatttgctggat
attgatgcaccagtcacagtttgtggggacatacatggacaattcttcgacttgatgaag
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagagcgtgtctatgacgcctgcatggat
gcctttgactgcctgcccttggctgccctgatgaaccagcaattcctgtgtgtacatggt
ggtttgtctccagagatcaacactttagatgacatcagaaaattagaccgattcaaagaa
ccacctgcttacggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatccatactccgagcc
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaacatcaggcaattcaactgttctcctcatcca
tactggcttcccaatttcatggatgttttcacttggtccctgccatttgttggggagaaa
gtgaccgagatgctggtaaatgtcctcaacatctgctcagatgatgaactggggtcagaa
gaagatggatttgatggagccacagccgcagcccggaaggaggtgataaggaacaagatc
agagccattggcaagatggccagagtgttctcggttctcagagaagagagtgagagcgtg
ctgacgctgaaaggcctgacgcccacgggcatgctccccagcggagtgctctctggaggg
aagcaaacactgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacagcataagatcactagcttcgaggaggccaagggcttagaccgaattaac
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggcgctcgcctcagagactaacggcacggacagcaatggcagtaacagcagcaatatc
cagtga

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