KEGG   Camelus ferus (Wild Bactrian camel): 102507309
Entry
102507309         CDS       T02979                                 
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr04010  MAPK signaling pathway
cfr04020  Calcium signaling pathway
cfr04022  cGMP-PKG signaling pathway
cfr04024  cAMP signaling pathway
cfr04260  Cardiac muscle contraction
cfr04261  Adrenergic signaling in cardiomyocytes
cfr04270  Vascular smooth muscle contraction
cfr04723  Retrograde endocannabinoid signaling
cfr04725  Cholinergic synapse
cfr04726  Serotonergic synapse
cfr04727  GABAergic synapse
cfr04911  Insulin secretion
cfr04912  GnRH signaling pathway
cfr04921  Oxytocin signaling pathway
cfr04924  Renin secretion
cfr04925  Aldosterone synthesis and secretion
cfr04927  Cortisol synthesis and secretion
cfr04929  GnRH secretion
cfr04934  Cushing syndrome
cfr04935  Growth hormone synthesis, secretion and action
cfr05010  Alzheimer disease
cfr05020  Prion disease
cfr05022  Pathways of neurodegeneration - multiple diseases
cfr05207  Chemical carcinogenesis - receptor activation
cfr05410  Hypertrophic cardiomyopathy
cfr05412  Arrhythmogenic right ventricular cardiomyopathy
cfr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102507309 (CACNA1S)
   04020 Calcium signaling pathway
    102507309 (CACNA1S)
   04024 cAMP signaling pathway
    102507309 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    102507309 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102507309 (CACNA1S)
   04929 GnRH secretion
    102507309 (CACNA1S)
   04912 GnRH signaling pathway
    102507309 (CACNA1S)
   04921 Oxytocin signaling pathway
    102507309 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    102507309 (CACNA1S)
   04924 Renin secretion
    102507309 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    102507309 (CACNA1S)
   04927 Cortisol synthesis and secretion
    102507309 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    102507309 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    102507309 (CACNA1S)
   04270 Vascular smooth muscle contraction
    102507309 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    102507309 (CACNA1S)
   04725 Cholinergic synapse
    102507309 (CACNA1S)
   04726 Serotonergic synapse
    102507309 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    102507309 (CACNA1S)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    102507309 (CACNA1S)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102507309 (CACNA1S)
   05020 Prion disease
    102507309 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    102507309 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102507309 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    102507309 (CACNA1S)
   05414 Dilated cardiomyopathy
    102507309 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102507309 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:cfr04040]
    102507309 (CACNA1S)
Ion channels [BR:cfr04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   102507309 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans GPHH Ca_chan_IQ PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 102507309
NCBI-ProteinID: XP_032322744
UniProt: A0A8B8RZG1
LinkDB
Position
23:complement(12273297..12332607)
AA seq 1871 aa
MEPPSPQDEGLRKKQPKKPVPEVLPRPPRALFCLTLENPVRKACISVVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNIIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYLSWITQGEVMDVDDLKEGKLALDEGGSDTESLYEIAGLNKIIQFVRHWRQWNRI
FRWKCHDVVKSRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDVANRVLLSLFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEVLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRFDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGILAYGGPTYPGVLVSIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSKGLPDKSEEEKTTLTKKLDQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEVPISPRPRPLAELQLKEKAVPIPDASAFF
IFSPTNRIRILCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSTISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDV
SKMTEEECRGYYYVYKDGDPTQVELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPELL
YKAIDANEEDKGPVYNHRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTVIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTSFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLMAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPH
VMANQRPLQFTEIEMEELESPVFLEDFPQHPSTNPLARANTNNANANATGGNSNHGNRWA
FSSVHYEGEFPGETETPAARGGAFGQHWGTLDPHSKSCVERLKGPRTQRAVPGAQAPPTP
CQAWVESPVAEERSPTPESLPKEAPPGNRTEDRTPRCPAPATALLIREALVRGGLDTLAT
DANFVKATGQALAEACQMEPEEVEVAAAELLKGREAPEGVASAPGRLGLGSSLGSLDQLQ
GSQETLIPRRL
NT seq 5616 nt   +upstreamnt  +downstreamnt
atggagccaccctcgccccaggatgagggcctgaggaagaaacagcccaagaagcctgtt
cccgaggtcctgcccaggccgccccgggccttgttctgtctgaccctcgagaaccccgtg
aggaaagcctgcatcagcgtcgtggagtggaaacccttcgagaccatcatcttactcacc
atctttgccaactgtgtggcgctggccgtgtacctgcccatgccggaggatgacaacaac
actctgaacctcggcctggagaagctggagtacttcttcctcatcgtcttctccatcgag
gccgccatgaagatcatcgcttacggcttcctgttccaccaggacgcctacctgcgcagc
ggctggaacgtgctggacttcatcatcgtcttcctgggggtcttcaccgtgatcctggag
caggttaacattatccagagcaacacggccccgatgagcagcaagggagccggcctggat
gtcaaggcgctgagagccttccgcgtgctcaggcccctgcggctggtgtccggggtgcca
agcctgcaggtggtcctcaactccatcttcaaggccatgctacccctgttccacatcgcc
ctgctggtcctcttcatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgctacttcatcgggacggacatcgtggccacggtggagaatgag
aagccgtcgccctgcgcccggacgggctcaggccgcccctgcaccatcaacggcagcgag
tgccggggcggctggccgggccccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctcactgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaacgacgccatcgggaacgagtggccctggatctactttgtcaccctcattctgctg
ggctccttcttcattctcaacctggtgctgggcgtcctgagtggggagttcaccaaggaa
cgggagaaggccaagtccaggggaaccttccagaagctgcgggagaagcagcagctggag
gaggacctccggggctacctgagctggatcacgcagggcgaggtcatggacgtggacgac
ttgaaagaagggaagctggctttggatgaaggcggctcagacacggagagcttgtacgaa
atcgcgggcttgaacaaaatcatccagtttgtccgtcactggaggcagtggaaccgcatc
ttccgctggaagtgccacgacgtggtgaagtccagggtcttctactggctggtcatcttg
atcgttgccctcaacaccctgtccatcgcctccgagcaccaccaccagcctctctggttg
acccacttgcaagacgtggccaaccgcgtgctgctgtccctgttcacggtggagatgctg
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggaggtcctgctggtggagtcgggcgccatgacg
cccctgggcatctccgtgctgcgctgcatccgcctcctccggatcttcaagatcaccaag
tactggacgtccctgagcaacctggtggcctccctgctcaactccatccgctccatcgcc
tccctgctgctgctgctcttcctcttcatcgtcatcttcgccctgctgggcatgcagctc
tttgggggcaggttcgacttcgaggacaccgaggtgcggcgcagcaacttcgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctgacgggcgaggactggaactccgtgatg
tacaacgggatcctggcctacggcgggccgacctaccccggggtgctcgtgtccatctac
ttcatcatcctgttcgtctgcggcaactacatcctgctcaacgtcttcctggccatcgcc
gtggacaacctggcggaggcggagagcctgacttctgcccagaaggccaaggccgaggag
cggaggcgcaggaagatgtccaaggggctcccggacaagtcagaggaggagaagacaacg
ttgaccaagaagctggaccagaaacccaagggggagggcatccccaccacagccaagctg
aagatcgacgagtttgagtccaacgtcaatgaggtgaaggacccctacccctcggccgac
ttcccaggggatgatgaagaagatgagcccgaggtcccaattagcccccggccacgtccg
ctggccgagctgcagctgaaggagaaggccgtgcccatcccagatgccagcgccttcttc
atcttcagccccaccaacaggatccgtatcctctgtcaccgcattgtcaacgccacctgg
ttcaccaacttcatcttgctcttcatcctgctcagcagtgcagcgctggctgctgaggac
cccatcagggctgagtccgtgaggaatcagatccttgggtattttgatatcgcatttacc
tctgtcttcactgtggagattgtcctcaagatgaccacctacggggccttcctgcacaag
ggctccttctgccgcaactacttcaacatgctggacctgctggtggtggccgtgtccctc
atctccatgggacttgagtccagcaccatctctgtggtgaaaatcctgagggtactgaga
gtgctccgaccactccgggccatcaacagagccaaagggctgaagcacgtggtgcagtgc
gtgtttgtggccatccgcaccatcgggaacatcgtcctggtcaccacgctgctccagttc
atgttcgcctgcatcggtgtccagctcttcaaggggaagttcttcagctgcaatgacgtg
tccaagatgacagaggaggagtgcaggggctactactacgtgtacaaggatggggacccc
acgcaggtggagttgcgtccccgccagtggatacacaacgacttccacttcgacaacgtg
ctctcggccatgatgtcactcttcacggtgtccaccttcgagggatggccggagctgctg
tacaaggccattgatgctaacgaggaggacaagggccccgtgtacaaccaccgcgtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttc
gtgggctttgtcatcgtcaccttccaggagcagggggagacggagtacaagaactgcgag
ctggacaagaaccagcgccagtgtgtgcagtacgccctgaaggcccgccccctgaggtgc
tacatccccaaaaacccataccagtaccaggtgtggtacgtcgtcacctcctcctacttc
gagtacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagagcagatgaaccacatctcagacatcctcaacgtggccttcaccgtcatc
ttcaccctggagatgatcctcaagctcatggcgttcaaggccaggggatactttggggac
ccctggaacgtgtttgacttcctgattgtcatcggcagcatcatcgacgtcattctcagc
gagatcgacactttcctggcctccagcgggggactgtattgcctgggtggcggctgcggg
aacgttgaccccgacgagagcgcccgcatctccagcgcctttttccgcctgttccgcgtc
atgaggctgatcaagctgctgagccgtgcggagggcgtgcgcacgttgctctggaccttc
atcaagtccttccaggccctgccctacgtggctctgctcatcgtcatgctctttttcatc
tacgctgtcatcggcatgcagatgtttgggaagatcgccatggtggacgggacccagatc
aaccgaaacaacaacttccagaccttcccccaggctgtgctgctgctcttcaggtgcgcc
acgggcgaggcgtggcaggagatcctgctggcctgcagctacggcaagctgtgcgacccc
gagtcggactacgcccccggggaggagcacacgtgcggcaccagcttcgcctactactac
ttcatcagcttctacatgctgtgcgccttcctgatcatcaacctctttgtggccgtcatc
atggacaactttgactacctcacgcgggactggtccatcctgggtccccaccacctggac
gagttcaaggccatctgggcagagtatgacccggaggctaagggcagaatcaaacatctg
gatgtggtgaccctgctgagaaggatccagccccctctgggctttgggaagttctgccca
caccgggtggcatgtaagcggctggtgggcatgaacatgcccctgaacagcgatggtacg
gtcaccttcaatgccaccctcttcgctctggtccgcacagcactcaagatcaagacggaa
ggtaacttcgagcaggccaacgaggagctgcgggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcatccctccaataggagatgatgaggtgacggtg
gggaagttctacgccacgtttctcatccaggagcacttccgaaagttcatgaagcgccag
gaggagtattatgggtatcggcccaagaaggacactgtgcagatccaggccgggctgcgg
accattgaggaagaggcagcccctgagatccgccgcaccatctcaggggacctgatggct
gaggaggagctggagagagccatggtggaggccgcgatggaggaagggatattccggagg
accggaggtctgttcggccaggtggacaacttcctggaaaggaccaactccctgccccac
gtcatggccaaccagaggcccctccagttcactgaaatagagatggaggagctggaatcg
cctgtcttcttggaggacttccctcagcatccaagcaccaaccccctggctcgagccaac
accaacaatgccaatgccaacgccacgggtggcaacagcaaccatggcaaccgctgggcg
ttctccagtgtccactacgagggggagttcccgggagagacagagacacctgccgccagg
ggaggagcctttggccagcactgggggaccctggacccccacagcaaatcctgtgtggaa
aggctgaagggacctcggacccagagagctgtgcccggagcgcaggcacctcccacccct
tgccaggcgtgggtggagtctcccgtggctgaggagaggagccccacaccagagtccctg
cccaaggaggcaccgcctggcaataggactgaggaccgcacccccaggtgcccagctcca
gccacagccctgctgatccgagaggctctggttcgagggggcctggacaccctggcaact
gatgctaactttgtcaaggcgacaggccaggccctggccgaggcctgccagatggaacca
gaggaggtggaggtggcagcagcagagcttctgaaggggcgtgaggccccagagggcgtg
gccagcgccccggggcgcttgggcctcgggtcctccctgggcagcctcgaccagcttcag
ggctcccaggagacccttattccccgcaggctgtga

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