KEGG   Camelus ferus (Wild Bactrian camel): 102509448
Entry
102509448         CDS       T02979                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr01522  Endocrine resistance
cfr04010  MAPK signaling pathway
cfr04012  ErbB signaling pathway
cfr04014  Ras signaling pathway
cfr04024  cAMP signaling pathway
cfr04068  FoxO signaling pathway
cfr04071  Sphingolipid signaling pathway
cfr04137  Mitophagy - animal
cfr04140  Autophagy - animal
cfr04141  Protein processing in endoplasmic reticulum
cfr04210  Apoptosis
cfr04215  Apoptosis - multiple species
cfr04217  Necroptosis
cfr04310  Wnt signaling pathway
cfr04380  Osteoclast differentiation
cfr04510  Focal adhesion
cfr04517  IgSF CAM signaling
cfr04519  Cadherin signaling
cfr04530  Tight junction
cfr04620  Toll-like receptor signaling pathway
cfr04621  NOD-like receptor signaling pathway
cfr04622  RIG-I-like receptor signaling pathway
cfr04625  C-type lectin receptor signaling pathway
cfr04657  IL-17 signaling pathway
cfr04658  Th1 and Th2 cell differentiation
cfr04659  Th17 cell differentiation
cfr04660  T cell receptor signaling pathway
cfr04664  Fc epsilon RI signaling pathway
cfr04668  TNF signaling pathway
cfr04722  Neurotrophin signaling pathway
cfr04723  Retrograde endocannabinoid signaling
cfr04728  Dopaminergic synapse
cfr04750  Inflammatory mediator regulation of TRP channels
cfr04910  Insulin signaling pathway
cfr04912  GnRH signaling pathway
cfr04914  Progesterone-mediated oocyte maturation
cfr04917  Prolactin signaling pathway
cfr04920  Adipocytokine signaling pathway
cfr04926  Relaxin signaling pathway
cfr04930  Type II diabetes mellitus
cfr04931  Insulin resistance
cfr04932  Non-alcoholic fatty liver disease
cfr04933  AGE-RAGE signaling pathway in diabetic complications
cfr04935  Growth hormone synthesis, secretion and action
cfr04936  Alcoholic liver disease
cfr05010  Alzheimer disease
cfr05012  Parkinson disease
cfr05016  Huntington disease
cfr05017  Spinocerebellar ataxia
cfr05020  Prion disease
cfr05022  Pathways of neurodegeneration - multiple diseases
cfr05132  Salmonella infection
cfr05133  Pertussis
cfr05135  Yersinia infection
cfr05142  Chagas disease
cfr05145  Toxoplasmosis
cfr05152  Tuberculosis
cfr05161  Hepatitis B
cfr05162  Measles
cfr05166  Human T-cell leukemia virus 1 infection
cfr05167  Kaposi sarcoma-associated herpesvirus infection
cfr05169  Epstein-Barr virus infection
cfr05170  Human immunodeficiency virus 1 infection
cfr05171  Coronavirus disease - COVID-19
cfr05200  Pathways in cancer
cfr05208  Chemical carcinogenesis - reactive oxygen species
cfr05210  Colorectal cancer
cfr05212  Pancreatic cancer
cfr05231  Choline metabolism in cancer
cfr05415  Diabetic cardiomyopathy
cfr05417  Lipid and atherosclerosis
cfr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102509448 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102509448 (MAPK10)
   04012 ErbB signaling pathway
    102509448 (MAPK10)
   04014 Ras signaling pathway
    102509448 (MAPK10)
   04310 Wnt signaling pathway
    102509448 (MAPK10)
   04668 TNF signaling pathway
    102509448 (MAPK10)
   04068 FoxO signaling pathway
    102509448 (MAPK10)
   04071 Sphingolipid signaling pathway
    102509448 (MAPK10)
   04024 cAMP signaling pathway
    102509448 (MAPK10)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102509448 (MAPK10)
   04519 Cadherin signaling
    102509448 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102509448 (MAPK10)
   04137 Mitophagy - animal
    102509448 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    102509448 (MAPK10)
   04215 Apoptosis - multiple species
    102509448 (MAPK10)
   04217 Necroptosis
    102509448 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102509448 (MAPK10)
   04530 Tight junction
    102509448 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102509448 (MAPK10)
   04621 NOD-like receptor signaling pathway
    102509448 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    102509448 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    102509448 (MAPK10)
   04660 T cell receptor signaling pathway
    102509448 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    102509448 (MAPK10)
   04659 Th17 cell differentiation
    102509448 (MAPK10)
   04657 IL-17 signaling pathway
    102509448 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    102509448 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102509448 (MAPK10)
   04920 Adipocytokine signaling pathway
    102509448 (MAPK10)
   04912 GnRH signaling pathway
    102509448 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    102509448 (MAPK10)
   04917 Prolactin signaling pathway
    102509448 (MAPK10)
   04926 Relaxin signaling pathway
    102509448 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    102509448 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    102509448 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    102509448 (MAPK10)
   04722 Neurotrophin signaling pathway
    102509448 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102509448 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102509448 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102509448 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    102509448 (MAPK10)
   05231 Choline metabolism in cancer
    102509448 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102509448 (MAPK10)
   05212 Pancreatic cancer
    102509448 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102509448 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    102509448 (MAPK10)
   05161 Hepatitis B
    102509448 (MAPK10)
   05171 Coronavirus disease - COVID-19
    102509448 (MAPK10)
   05162 Measles
    102509448 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102509448 (MAPK10)
   05169 Epstein-Barr virus infection
    102509448 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102509448 (MAPK10)
   05135 Yersinia infection
    102509448 (MAPK10)
   05133 Pertussis
    102509448 (MAPK10)
   05152 Tuberculosis
    102509448 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102509448 (MAPK10)
   05142 Chagas disease
    102509448 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102509448 (MAPK10)
   05012 Parkinson disease
    102509448 (MAPK10)
   05016 Huntington disease
    102509448 (MAPK10)
   05017 Spinocerebellar ataxia
    102509448 (MAPK10)
   05020 Prion disease
    102509448 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    102509448 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102509448 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    102509448 (MAPK10)
   05415 Diabetic cardiomyopathy
    102509448 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102509448 (MAPK10)
   04936 Alcoholic liver disease
    102509448 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    102509448 (MAPK10)
   04931 Insulin resistance
    102509448 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102509448 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102509448 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfr01001]
    102509448 (MAPK10)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102509448 (MAPK10)
Protein kinases [BR:cfr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102509448 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 102509448
NCBI-ProteinID: XP_006190078
UniProt: A0A8B8UJ13
LinkDB
Position
2:41284285..41726027
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMTSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccagttctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaacctaaagcctattggctccggggctcagggaatagtttgtgct
gcatatgacgctgtccttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacacatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggag
ttagaccatgaacgaatgtcttacctgctgtaccaaatgttgtgtggcatcaagcacctt
cactctgctggaattattcacagggacttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctagactttggactggccaggacagcaggcacgagcttcatgatg
actccgtatgtggtgacacgttattacagggcccctgaggtcattctgggcatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtaattgagcaactagga
acgccatgcccagaattcatgaagaaattgcaacccacagtaagaaactacgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactccgagcacaataaactcaaagccagccaagccagggacttgttgtcaaagatgcta
gtgattgacccagcgaagaggatatcagtggacgacgccttacagcatccgtacatcaat
gtctggtatgaccctgccgaagtggaggcgcccccacctcagatatatgacaaacagttg
gatgaaagagaacacaccattgaagagtggaaagaacttatctacaaggaagtaatgact
tcagaagagaagactaagaacggtgttgtgaaaggacagccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccgtcctcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcttcggcaggacccctg
ggttgttgcaggtga

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