Camelus ferus (Wild Bactrian camel): 102514718
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Entry
102514718 CDS
T02979
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
cfr
Camelus ferus (Wild Bactrian camel)
Pathway
cfr00260
Glycine, serine and threonine metabolism
cfr00630
Glyoxylate and dicarboxylate metabolism
cfr00670
One carbon pool by folate
cfr01100
Metabolic pathways
cfr01200
Carbon metabolism
cfr01230
Biosynthesis of amino acids
cfr01240
Biosynthesis of cofactors
cfr01523
Antifolate resistance
cfr04981
Folate transport and metabolism
Module
cfr_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
cfr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102514718 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102514718 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102514718 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102514718 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102514718 (SHMT2)
Enzymes [BR:
cfr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102514718 (SHMT2)
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
102514718
NCBI-ProteinID:
XP_006182551
UniProt:
A0A8B6YDD5
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Position
12:22803450..22808435
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AA seq
504 aa
AA seq
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MLPFSLFWATRPLQRCGQLVGMVIRCQHSEAAQTPTGEATGGWSGQESLSDSDPEMWELL
RREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFQHADVVTTTTHKTLRGARSGLIFFRKGVRAVD
PKTGQEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQARTPMFREYSLQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRKVVDFIDEGVNIGLEVKRRTAKLQDFKSFLLKDPETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctacctttctctttgttctgggcgactcggcctctgcagagatgtggtcagctggtc
gggatggtcataaggtgccagcacagcgaagcagcccagactccaactggagaagcaact
gggggctggtcaggccaggagagtctatcagacagtgatcctgaaatgtgggagctactg
cggagagagaaggacaggcaatgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattacgggggagctgaagtagtggatgaaattgaactgctgtgtcag
cgccgggccttggaggcctttgacctggaccctgcacagtggggagtcaatgtccagccc
tactctgggtccccagccaatctggctgcctacacagctcttctgcagcctcatgaccga
ataatggggctggacctgcctgatgggggccatctcacccatggctatatgtctgatgtc
aagcggatctccgccacttccatcttcttcgagtctatgccctataagctgaatccccag
accggcctcattgactacgaccagctggcactcactgctcggctcttccgaccgagactc
atcatagccggtaccagtgcctatgcgcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcacacctgctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttccagcatgcggacgttgtcaccaccaccactcacaag
acccttcgcggggccaggtcaggactcatcttcttccggaagggggtgcgagctgtggac
cccaagactggccaagagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggaccccacaaccatgccattgctgcagtggctgtggccctaaag
caggcccgcacccccatgttccgggagtactccctgcaggtcctgaagaatgcgcgggcc
atggctgatgccctgctagagcgaggctactcgctggtgtctggtggcactgacaaccac
ctagtgctggtagacctgcggcccaagggccttgatggggctcgagctgagcgggtgctg
gaactcgtatccatcacggccaacaagaacacctgtcctggagatcgaagcgccatcaca
cctgggggcctgcggcttggggccccagctctgacttcaagacagttccgcgaggatgac
ttccggaaagttgtggactttatcgatgaaggcgtcaacattggcttggaagtgaagaga
aggactgccaaactccaggatttcaaatccttcttgctcaaagacccagaaacaagtcat
cggctggctgacctcaggcaaagggtggagcagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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