KEGG   Camelus ferus (Wild Bactrian camel): 102515954
Entry
102515954         CDS       T02979                                 
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
  KO
K09490  endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr03060  Protein export
cfr04141  Protein processing in endoplasmic reticulum
cfr04612  Antigen processing and presentation
cfr04918  Thyroid hormone synthesis
cfr05012  Parkinson disease
cfr05014  Amyotrophic lateral sclerosis
cfr05020  Prion disease
cfr05022  Pathways of neurodegeneration - multiple diseases
cfr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    102515954 (HSPA5)
   04141 Protein processing in endoplasmic reticulum
    102515954 (HSPA5)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    102515954 (HSPA5)
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    102515954 (HSPA5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102515954 (HSPA5)
   05014 Amyotrophic lateral sclerosis
    102515954 (HSPA5)
   05020 Prion disease
    102515954 (HSPA5)
   05022 Pathways of neurodegeneration - multiple diseases
    102515954 (HSPA5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102515954 (HSPA5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:cfr03110]
    102515954 (HSPA5)
   04131 Membrane trafficking [BR:cfr04131]
    102515954 (HSPA5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfr04147]
    102515954 (HSPA5)
Enzymes [BR:cfr01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.10  non-chaperonin molecular chaperone ATPase
     102515954 (HSPA5)
Chaperones and folding catalysts [BR:cfr03110]
 Heat shock proteins
  HSP70 / DNAK
   102515954 (HSPA5)
Membrane trafficking [BR:cfr04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    102515954 (HSPA5)
 Autophagy
  ER-phagy
   ER stress-related proteins
    102515954 (HSPA5)
Exosome [BR:cfr04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   102515954 (HSPA5)
  Exosomal proteins of other body fluids (saliva and urine)
   102515954 (HSPA5)
  Exosomal proteins of colorectal cancer cells
   102515954 (HSPA5)
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A FtsA DDR FGGY_C ParM_N
Other DBs
NCBI-GeneID: 102515954
NCBI-ProteinID: XP_006187781
UniProt: S9Y3W1
LinkDB
Position
4:complement(66236042..66240476)
AA seq 654 aa
MKLSLVAAVLLLLGAALAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq 1965 nt   +upstreamnt  +downstreamnt
atgaagctctccctggtggctgcggtgctgctgctgctcggcgcggcgctggccgaggag
gaggacaagaaagaggatgtaggcacggtggtcggtatcgacctgggcaccacctactcc
tgcgtgggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc
atcacgccgtcttacgtggccttcactcctgaaggggagcgtctgatcggcgatgcagcc
aagaaccaactcacctccaatcctgagaacacggtcttcgacgccaagcggctcattggt
cggacgtggaacgacccgtctgtgcagcaggacatcaagttcttgcctttcaaggtggtt
gaaaagaaaactaaaccatacattcaagttgatattggaggtggacaaacaaagacattt
gctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggcttat
ttgggaaagaaggttactcatgcagttgttactgtacctgcctatttcaacgatgcccaa
cgccaggcaaccaaagacgctggaactattgctggattgaatgttatgaggatcatcaat
gagcctacagcagctgctattgcttatggcctggataagagggaaggggagaagaacatc
ctggtgtttgacctgggtggtggaacctttgatgtgtctcttctcaccattgataatggt
gtctttgaagtcgtggccactaatggagatactcatctgggtggagaagactttgaccag
cgtgtcatggagcacttcatcaagctttacaaaaaaaagactggcaaagatgtgcggaaa
gacaacagagctgtgcagaaactccggcgtgaggtagagaaggcgaaacgggccctgtct
tctcaacatcaagcaagaatcgaaattgagtccttctatgaaggagaggacttctctgaa
accttgactcgggccaaatttgaagagctaaacatggacctgttccgttctaccatgaag
cctgtccagaaagtgctggaagattctgatttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcattaacccagatgaggctgtagcgtatggtgctgctgtc
caggctggtgtactctctggtgatcaagatacaggtgatctggtactgcttgatgtgtgt
ccccttacacttggtattgaaaccgtgggaggtgtcatgaccaaactgattccaaggaac
actgtggtgcccaccaagaagtctcagatcttttctacagcatctgataatcagccgact
gttaccatcaaggtctatgaaggtgaacgacccctgacgaaagacaatcaccttctggga
acttttgatctgactggaattcctcctgctccccgtggggtcccacagatcgaagtcacc
tttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggcaac
aaaaataagatcacgattaccaatgaccaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcattgac
accagaaatgaattggaaagctatgcctactctctaaagaatcagattggagataaagaa
aagctgggaggtaaactttcttccgaagataaggagaccatggaaaaagccgtggaggaa
aagattgagtggttagaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggagctagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaaccagcagacaaagatgagttgtaa

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