Camelus ferus (Wild Bactrian camel): 102519873 Help Entry 102519873         CDS       T02979                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism cfr  Camelus ferus (Wild Bactrian camel) Pathway cfr01521   EGFR tyrosine kinase inhibitor resistance cfr04151   PI3K-Akt signaling pathway cfr04217   Necroptosis cfr04380   Osteoclast differentiation cfr04550   Signaling pathways regulating pluripotency of stem cells cfr04620   Toll-like receptor signaling pathway cfr04621   NOD-like receptor signaling pathway cfr04630   JAK-STAT signaling pathway cfr04658   Th1 and Th2 cell differentiation cfr04659   Th17 cell differentiation cfr05140   Leishmaniasis cfr05145   Toxoplasmosis cfr05152   Tuberculosis cfr05160   Hepatitis C cfr05161   Hepatitis B cfr05162   Measles cfr05163   Human cytomegalovirus infection cfr05164   Influenza A cfr05165   Human papillomavirus infection cfr05166   Human T-cell leukemia virus 1 infection cfr05167   Kaposi sarcoma-associated herpesvirus infection cfr05168   Herpes simplex virus 1 infection cfr05169   Epstein-Barr virus infection cfr05171   Coronavirus disease - COVID-19 cfr05200   Pathways in cancer cfr05203   Viral carcinogenesis cfr05212   Pancreatic cancer cfr05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:cfr00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102519873 (JAK1)    04151 PI3K-Akt signaling pathway     102519873 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102519873 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102519873 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102519873 (JAK1)    04621 NOD-like receptor signaling pathway     102519873 (JAK1)    04658 Th1 and Th2 cell differentiation     102519873 (JAK1)    04659 Th17 cell differentiation     102519873 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     102519873 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102519873 (JAK1)    05203 Viral carcinogenesis     102519873 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102519873 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     102519873 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102519873 (JAK1)    05161 Hepatitis B     102519873 (JAK1)    05160 Hepatitis C     102519873 (JAK1)    05171 Coronavirus disease - COVID-19     102519873 (JAK1)    05164 Influenza A     102519873 (JAK1)    05162 Measles     102519873 (JAK1)    05168 Herpes simplex virus 1 infection     102519873 (JAK1)    05163 Human cytomegalovirus infection     102519873 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     102519873 (JAK1)    05169 Epstein-Barr virus infection     102519873 (JAK1)    05165 Human papillomavirus infection     102519873 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     102519873 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102519873 (JAK1)    05140 Leishmaniasis     102519873 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102519873 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cfr01001]     102519873 (JAK1) Enzymes [BR:cfr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102519873 (JAK1) Protein kinases [BR:cfr01001]  Non-receptor tyrosine kinases   JAK family [OT]    102519873 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  102519873 NCBI-ProteinID:  XP_032350370 UniProt:  A0A8B8U823 LinkDB All DBs Position 13:complement(48009579..48220597) Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPAPGVEVLFYLPDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNHTITIDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN RFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNSFSYFPEITHIVIKESVVSVNKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRGFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LMDYKDDEGTAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcaatatctaaacataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagaccgaggtgaatctggaggcccctgcgcccggggtggaggtgctcttc tatctcccggacagggagcccctccggctgggcagcggagagtacacggcagaggagctg tgcatcagggcggcgcaggagtgctgtatctctcctctgtgtcataacctctttgccctg tatgatgagaacaccaagctctggtatgctccaaatcacaccatcaccatcgacgacaag acgtcgctccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat gataatgagcagtcagtatggcgacattccccaaagaagcagaagaatggctacgagaaa aaaaaagttccagatgcaacccctctccttgacgccagctcactggagtatctgtttgct cagggacagtacgatttggtcaagtgcctggctcccatccgagaccccaagacggagcag gacgggcatgatattgagaacgagtgtttgggaatggccgtcctggctatctcccactac gccatgataaagaagatgcagctgcccgagcttcccaaggatatcagctacaagcgatat attccagaaacactgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataacgttttcaaggatttcctaaaggagtttaacaacaagaccatctgcgacagcagc gtgtccacgcacgacctgaaggtgaagtacctggccaccttggagactctgacgaaacat tatggtgctgaaatatttgagacgtccatgctactgatctcgtcagaaaatgagatgaat cggtttcatccgaatgacagtggaaacgttctctactatgaagtgatggtgactggaaat cttggaatccaatggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa ctgaagcggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg gaagagtggaacagcttttcttacttccccgagatcactcacatcgtaatcaaggagtct gtggtcagcgttaataagcaggacaacaagaaaatggaactgaagctctcgtcccacgag gaggccttgtcttttgtgtccctggtggacggctacttccggctcacggcagatgcccac cattacctctgcaccgacgtggctcccccgctcattgtccacaacatacagaatggctgt catgggccaatctgcacagaatatgccatcaacaaattgcggcaagaaggaagcgaggag gggatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgttacc tgcttcgaaaagtctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag gtgcagaagggccgctacagcctgcacggctcagaccgcggcttccccagcctcggggac ctcatgagccacctgaagaagcagatcctgcgcacagacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagaaatctccaacctgctggtggccactaagaaagcc caagagtggcagcccgtctaccccatgagccagctgagttttgatcggatcctcaagaaa gatattatgcaaggcgagcaccttgggagaggcacacggacacacatctactctgggacc ctcatggattacaaggatgacgaaggaactgccgaagagaagagaataaaagtgatcctc aaagtgttagaccccagccacagggacatttccctggccttctttgaggcagccagcatg atgagacaggtctcccataaacacatcgtgtacctctatggcgtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggagggggggcccctggacctcttcatgcaccgg aaaagtgatgtcctcaccacaccctggaaattcaaagttgccaagcagctggccagcgcc ctgagttacttggaggataaagacctggtccacggaaacgtgtgcactaaaaacctcctc ctggcccgcgagggcattgacagcgagtgcggcccgttcatcaagctcagtgaccccggc atccccatcacggtgctgtccagacaagagtgcatagaacgaatcccatggattgctccc gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acactctgggaaatctgctacaatggcgagatccccttgaaagacaagacactgattgag aaagagaggttctacgaaagccggtgcaggccagtgacaccatcttgtaaggagctggct gaccttatgacccgctgcatgaactacgaccccaaccagagaccgttcttccgagccatc atgagagacatcaacaagctggaggagcagaatccagacatcgtatcagaaaaaaagcca gcaaccgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg ggagagggccacttcgggaaggttgagctctgcagatacgaccccgagggggacaataca ggggagcaggtggctgtcaaatctctgaagcctgagagtggagggaaccacatagctgat ctgaagaaggaaatcgaaatcttaagaaacctttatcacgagaacattgtgaagtacaaa ggcatctgcaccgaggacggaggaaatggtattaagctcatcatggaatttctgccttcg ggaagccttaaggaatatcttccaaagaacaagaacaaaattaacctcaaacagcagtta aaatatgctgttcagatttgcaaggggatggactacctgggttctcggcagtacgttcac cgggacttggcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggagac ttcggtctgaccaaagcaattgaaactgataaggagtattacacagtcaaggacgaccgg gacagccctgtgttctggtatgctccagaatgtttaattcagtgtaaattttatatcgcc tctgatgtctggtcttttggagtgactctgcacgagctgcttacttactgtgattcagat tccagtcccatggcattgttcctgaaaatgataggcccaactcatggccagatgacggta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctaactgtcca gaagaggtttatcaactcatgagaaaatgctgggaattccaaccatctaatcggacaacc tttcaaaaccttattgaaggatttgaagcacttttaaaataa

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