Camelus ferus (Wild Bactrian camel): 102519957 Help Entry 102519957         CDS       T02979                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism cfr  Camelus ferus (Wild Bactrian camel) Pathway cfr04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cfr00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     102519957 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cfr03036]     102519957 (SYNE1) Chromosome and associated proteins [BR:cfr03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     102519957 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH RhiE-like_linker Motif Other DBs NCBI-GeneID:  102519957 NCBI-ProteinID:  XP_032341079 UniProt:  A0A8B8TFS0 LinkDB All DBs Position 8:complement(61593154..62021024) Genome browser AA seq 8832 aa AA seqDB search MATSRAASRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALQFLEGRKSMYRGSPIKLVNINSTD IADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSTSSVDSMVSSETASPPSKRKVA TKIQGNAKKALLKWAQYTAKQTGTEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGRS NRENLEEAFRIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKQYPDIHSTGADGQE NDEILPGFPSFANSIQILKREDRLVLKETKVWIEQFERDMTRAQMTESNLQDKYQSFKHF RVQYEIKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGTI GAWLYRAEVALREEITIQQVHEETANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVNG IPVPADQLEDLAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRD SVELLLQNYISFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQW RNLSVEVRSVRSMLEEVIANWDRYGNTVASLQAWLEDAEKMLNQSEHAKKDFFRNLPHWI QQHAAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYT DCVTALSDFATEAHRKLSEPLEVSFINVKLLVQDLEDIEQRVPVMDAQYKIITKTAHLIT KESSQEEANEMFATMSRLREQLSKVKDCYSPLLYESQQLLIPLEELEKQMTAFYDSLGKI NEILTVLEHEAQSSSLFKEKHQELLACQESCKKAMTQIEKGSHSVQKFVTLSNVLKHFDQ TKLQRQVADVHVAFQNMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKG NPEDLLKRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGE APYHLLHLKIEVEKNRFLESVEECRAELDRETKLVPQEGSEKIIKEHRVFFGDKGPHHVC EKRLQLIEELCLKLPVRDPVRNTPETCHVTLKELRAAIGGTYAKLVENPDKWKDYSGRIS EFSCWISTKETQLKGIKNEAIDTANHGEVKRAVEEIRDGVTKKGETLSWLKSRLKILTEV SSENEAQKQGDELAKLSSSFKALGTLLSEVEKMVSNFGDCVQYKEIVKSSLEELITGSKE IQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQARQGEGGLPGRVREEL RKLESTLDSVEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLES LSSELEQTKEFSKRTEGIAVQAENLVKEASEIPLGPRNKQLLQQQAKSIKEQVKKLEDTL EEDIKTMEMVKNKWDHFGNNLETLSVWITEKEKELNALETSSSAMDTQIHQIKVTIQEIE SKVSSITGLEEEAQSFAQFITTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQQ QKFEENLRNIQQSVSEFEDKLADPIKMCSSATETYKVLQEHMDLCQALESLTSTVAALLA SAQKVADRDSSVREAEALQQRYEGLLRWAKERQTALEKLLAHWQRLEKELSTFTTWLERC EAAASSPEAVISADRVKVESELQLIQALQDEVVAQASIYSNLLQLKESLFSVASKEDVKM MKLHLEQLDERWRDLPQIISKRINFLQSVVAEHEQFDELLLSFSVWIKLFLSELQTTSEI SIMDHQAALTRHKDHAAEVESKKGELQSVQGHLAKLGALGRAEDLHLLQGKAEDCFQLFE EASQVVERRQLALSQLAAFLQSHTSLSGVLHRLRQTVEATSSMNKQQSDLLEKDLNDALQ DAKTLESTAISLDGLLTKAQYHLRSGGSEQRTSCRTAVDQLCFELERIQNLLGTKQSEAD ALAVLKKAFHDQKEELLKSIEDIEERADKERLKEPTRQALQQRLRVFNQLEDELNSHEHE LCWLKDKAKQIAQKDVAFAPEVDREVNRLEAIWDDTKKLIHENQGQCCGLIDLMREYQNL KSAVSKVLENASNVIVTRTTIKDQEDLKWALSKHETAKNEMYKKQKELDNFTSKGKQLLS ELKKIHSGDFILVKTDMESTVDKWLDISEKIEENMDRLRVSLSVWDEVLSCRDEIDGWSN SSVPQLAESISNLNDSLRAEEFLKEFESEVKKKALRLEELHSKVNDLKELTKNPETPPDL QFMEADLQQKLEHAKEITEEAKGTLKEFTAQSAQVEKFINDTATWLTKLEDSLMNCAQTE TCEGLKKVKEIQKELQSQQRSISSTQENLNSLCRKYHSVELESLGGAMLGLIKRHEAVSQ SCSKAQASLQDSLEKHFNESMQEFQEWFSGIKAAAKKSSDRTGDSKVLEAKLHDLQNILD SVSDGQSKLDAVTQEGETLYAHLSKQIVSSIQEQVTKANEEFQTFLKQCLKDKQALQDCA LELGSFEDQHRKLSLWIHEMDERLSTENLGESKQHIPEKKNEVHKIEMFLGELLAARESL DKLSQRGQLLSEEGHGAGKEGRLCSQLLTSYQNLLRVTKGKLRSCQVALQEHEALEEALQ SMWSWVKDVRDRLACAESTVGSKDALERRLLQVQDILLMKGEGEVKLNMAIGRGEQALRS SNKEGQKVIQTQLQTLKDVWANIMSSSIHAQSTLESVISQWNDYLEWKNQLEQWMESVDQ KLEHPLQLQPGLKEKFSLLDHFQSIVSEAGDHAGALQRLTAKARELYQKTEDDSFKEAAQ EELKTQFNDLLTVSKEKMRKVEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDTSGDSS AIQKKLSKIKELMDSRETGASRLGRVESLAPAVRQNTTASGCELLDTEMQALRADWKQWE DSVSQTQTSLENLVSQMALSEQEFSGQVAQLEQALEQFSALLTGWAQQLTLLEGKNTDKE IVECWHKGREILDALQKAEPQTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQA SKGCQNKEQILQQRFRRAFKDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSES EHGQHKLNMMVSKGELLNTLLTKEKANGIQAKIAAAKEDWKNFHSNLHQKESALENLKIQ MKDFEVSAEPVQEWLSKTEKTVHEGSDRLHDLPAKRREQQKLQSVLEEINCYEPQLHRLK EKAQQLWEGQAASRSFVHRVSQLSSQYLSLSNLTKEKVSRLDRIVAEHSQFSAGVRELQD WMTDAVHMLDSYCHPTSDKSVLDSRMLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPE GVPAIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEASLNE SERQYAELREKMAALGKAKLLNEEVLSHSSLLETIEVKGAGMTEHYVTQLEFQDLQERYG AIRERAKEAVTKSEKLVRLHQEYQRDLKAFEAWLAQEQEKLNRYSVLEGDAHTHETTLRD LQELQVHCAEGQALLNSVLHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLSETRTQFN NVVNKLRLMEQKFQQVDEWLKTLEEKVNLRTGRQSNRAAKEIQLHQMKKWHEEVTTYRDE VEDVGSRAQEILDESHVSSRTGCQATQLTSRYQALLLQVLEQIQFLEEEIQSLEESELSL SSYSDWYCSTHKNFKNVAAKIDKVDKAMMGKKMKTLEGLLKDMEKGQSLLKSAREKGERA VKYLEDGEAETLRKEIHDHVEQLKELTSTVRKEHLTLEKGLHLAKEFSDKYKALTQWIGE YQEILHIPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKD KIDQLQSDYQDLCSAGKEHVCSLEAKVRDHEDYNSELQEVEKWLLQMSGRLVAPDLMETS SLETITQQLAHHKAMMEEIAGFEDRLNNLKIKGDNLISQCADHLQAKLKQNVQAHVQGTK DSYSAVCSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLKPSTYPPLSRAEAVK QVKHFRALQEQARTYLDLLCSMCDLSNSSVKTTAKDIQQTEQMIEQRLAQAQNLTQGWEE IKHMKAELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFLKKLQSKQASVTTITE KVDKLTKKQESPEHKEISHLNDQWLDLCLQSTNLCLQREEDLQRTRDYHDCLDVVEVFLE KFTTEWDNLARSDAESTAVHLEALRKLALALQERKQAIDDLKERKQKMVEHLNLDDKELV KEQTSHLEQRWFQLEDLVKRKIQASITNLEELSVVRSRFQELMQWAEEQQPTIAEALKQS PPPDMAQSLLMDHLAICSELEAKQMLLKSLIKDADRVMTDLGLNERQMIQKALSDAQRHV NSLSDLVGQRRKYLNKALSEKTQFLIAVFQATSQIQQHERKIMFREHICLLPDDVSKQVK TCRSAQASLKTYQNEVTGLWAQGRELMKGATEQEKNEVLGKLQELQSVYDTVLQKCSHRL QELEKNLVSRKHFKEDFDKACHWLKQADIITFPEINLMNESPELHTQLAKYQHILEQSPE YENLLFTLQRTGQAMLPSLNEVDHSYLNEKLSALPLQFNVIVDLAKDKFYKVQEAILAQK EYASLIELTTQTLSELEDQFSKMSQVPTDLVVGEALSLQDGCRALAGEVAGLAEAVDELN QKKESFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLEKQL EGVKTEQSKVNEETLPAEEKLKLYHSLAGSLRESGILLKRVAVHLEDLVPHLDPLAYEKA KHQMQSWQEELKQLTSAIGATVTECESRMVQSRDFQTELSRSLDWLRGVKAELSGPLCLD LNLRDIQEEIRKVQIHQEEVQSSLRIMNALSDREQEKFTKAKELISADLQHTLAELAELD GDVQEALRTRQATLTQIYSQCQRYYQVFQAANDWLEDAHEMLQLTGNGLDVESAEESLKS HMEFFSTEDQFHSSLEELQGLVANLDPLIKPTGKEDLAQKMTSLEEKSQRILQDSHAQSD LLQRCAAQWQDYQKAREEVIELMNDAEKKLSEFSLLKTSSSLEAEEKLSEHKALVSVVNS FHEKIVALEGRASELERSGNDSSKATIGRSRTAVRQRWTRLRAVAQDQEKILEDAVDEWK GFNEKVKKATEMIDQLQEKLPGTSAEKASKAELLTLLEHHDALALELEQQQSAMGMLRRQ ALSMLRDGATPTPGAEPAAVQGVAVLQERCLNMQEKVKKNGQVAKQELKERQVVETHINS VKAWVQETKEYLGNPTLEVDAQLEELKILLTEATNHRQNIEKMAEEQKNKYLDLYTILPS ELSLQLAEVVLDLGTIHDQIQDKVKEVEQSKAMSQEFSRQIQKIAKDLTTILTKLRAKTD NLVQAKTDQKALGEELECCNLKLMELNEAVQKFSEQNGQLGKPLAKKIGKLTELHQQTIR QAENRLSKLSQAASHLEEYNEILELILKWIEKAKVLVHGKIAWNSASQLREQYISHQTML EESEEIDNDLEAMTEKLQSLDSVYHTGKMSQQVAELGRETEELRQMIKIRLQNLHDAAKD MKKFETELRNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQTCQ SALRIPEDVVTSLPLCHAALHLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLQEL IEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHAT MLLTVTEVEGLAEGTEDLDGELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEI SSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIPPGTLPSQELYEPGLEPSA TAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESLEHG RSPESQMAEHQSLPQALMDEILMLQEEISELQSALAEELVSESPESDPAEQLALQSTLTV LAERMSTIKMKASGKRQLLEEKLNDQLEEQRQEQALQRYLCEAEELDHWLLSTKATLDIA LGTPEEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAVKL RTLKGNLLELQRALHDKQLNIQQGTAQEKEESDADLAATQSPGVQEWLAQARTAWTHQRQ SSLQQQKELEQELAEQKSLLRSVASRGEEILTQHSAAETSGGAGEKPDVLSQELGMEGEK SPAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDGQAQDK SAVTSLLDGLNQAFEEVSSQGGGTKRQNIHLEQKLYDGVSATSTWLDDVEERLFVATALL PEETETCLFNQETLAKDIKEMSEEMDKNKILFSQAFPENGDNRGVIEDTLGCLLGRLSLL DSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADHKYIILQKLATVLEQPVAEQIEAIQQ AEDGLKELDAGIIELKRRADKLQVEQPSMQELSRLQDMYDELMVTIGSRRSGLNQNLALK SQYERALQDLADLLDTGREKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLF RKIISFAVQRETQFHTELMAQAAAVLKRAHKRGVELEYILETWSHLDEDHRELSRQLEVV EGSIPSVGLVEESEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQ LNQLGEHWLNDTNKVSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTV PQELEMVRDHLNAFLEFSKEVDAKSTLKSSVLSTGNQLLRLKKVDTAALRSELSHIDGQW TDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMAWISLMENVIQKDEENIKNSIGYKAIHE YLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQG LVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNAMKDCQDLE DLIKAKEKEVEKIEQNGLALIQNKNEEVSGIVMSTLRELNQTWADLDHMVEQLKILLKSV LDQWSHHKAAFDEINSRLTEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKSLQ KFGSITNQLLKECHPPVTETLTNTLKEVNLRWNNLLEEIAEQLHSSKALLQLWQRYKDYS KQCASTVQQQEGRTNELLKAATDKDIADDEVATWIQDCNDLLKGLETVKDSLFVLHELGE QLKQQVDASAASAIQSDQVSLSQHLGALEQALCKQQTMLQAGVLDYETFTKSLEALEAWI VEAEEILQAQDPSHSSDLSTIQERMEELKGQMLKFSSMVPDLDRLNELGYRLPLNDKEIK RMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQ HLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVI RRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYVPATGLGSVPIPLQQARTLFDDAQ FKEKVLLRQQGSYILTVEAGKQLLLSADGGAEAALQAELTEMQEKWRSASVHLEEQKKKL AFLLQDWEKCENGIADSLEKLRTFKKRLSQPLPDHHEELHVEQMHCKELETAVGSWTDDL AQLTLLKDTLCAYISADDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEK NKELCEWLTQMESKVSQNGDILIEEMIEKLRKDYQEEIAIAQENKIQLQQMGERLARASH ESKASEIEYKLGKINDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESEL AKPIVYDSCDSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDS IQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEEWLKISERTAAFPSSS GVLYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQR WDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQ LKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEDELDELRRYCQEVFGRVERYHK KLIRLPLPDDEQDLSDRELELDESAALSDLHWRDTSADSVLSPQPSSNPSLSLAQPLRSE RSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQEEKDFYLRGAVGLSDVV IPESPEAYVKLTESAIRNSSGDPSALESQIRQLGKALDDSRFHMQPTETIIRSKTPTGPE LDSSYRGYMKLLGECSGSIDSVKRLEHELKEEEDHFPGFVNLNSTETQTAGVIDRWELIQ AQALSKELRMKQNPQRRQQFDSDLSSTLAWLRETEDDLEQLRRLQLSTDIQSIALQIQKL KELQKAVDHRKAIILSINLCSSEFTQAGQEESQDLQDRLSQMNGRWDRVCSLLEEWRGLL QDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSNLDVEMLQDHHKQLTQIRRELLDT QLKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSSS QQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGSD SSLSEPQPARSGRAFLFRVLRAAVPLQLLLLLLVGLACLVPVSEEDYSCALSNNFARSFH PMLRYTNGPPPL NT seq 26499 nt NT seq  +upstreamnt  +downstreamnt atggcaacctccagggcagcctctcggtctcctcgggacatcgccaacgtgatgcaaagg ctacaagatgagcaagagatagtacagaaacgtacttttacaaaatggatcaactctcat ctggccaagcggaaacccccaatggtggtagatgatctttttgaagacatgaaagatggt gtgaagctacttgctctcctggaggtcctgtctgggcagaaactgccatgtgaacaggga cgccgtatgaagcggatccatgctgtggctaacatcggcacggcacttcagttccttgaa ggaaggaagtccatgtacagaggatcaccgataaaactagtcaacattaactccacggat atagcggatggccgaccctcgatagttcttggattgatgtggacgatcatcctgtatttc cagattgaggagctgaccagcaacctgccgcagctgcagtctctatccagcagcacatcc tccgtggacagcatggtcagctcggagaccgccagccccccgagcaaacggaaggtggcc accaagatccaaggaaatgctaagaaggctttgttaaagtgggctcagtacacagccaag cagactggaacagaagtgaaagacttcgggcggagctggagaagtggggttgcctttcat tcggtcatccacgctattcggccggaactggtggacttggagaaagtgaaagggagatct aaccgagaaaacctggaggaggctttcaggattgctgagacggaactgggaatcccgcga ctcctagatcccgaagatgtggacgtggataaaccagatgagaagtctattatgacttac gtagcccagtttctgaaacagtatcctgacatccacagcacaggcgctgatgggcaagag aatgatgaaatacttccaggtttcccatcttttgcaaattctatccaaattcttaagaga gaagataggctggttttgaaggaaacaaaagtttggatagaacaatttgaaagagatatg acgagggcacagatgacagaatcaaatttgcaggataaatatcagtcatttaagcacttc agagttcaatatgaaataaaaaggaaacagattgaacatttaatacagccgttacataga gatggcaaactgtcactcgaccaagcattggtaaagcagtcctgggatagagtgtcctcc aggctctttgattggcatattcagcttgataagtctcttcctgcccctctgggcaccatc ggggcctggttatacagagcagaggtggccctgcgagaggaaataaccattcagcaggtt cacgaggaaacggccaacacaatacagcggaagcgtgagcagcacaaggatctgcttcaa aacacagatgcccacaaaagagcattccatgaaatctaccggaccaggtctgttaacggg atcccagtgccagccgatcaattagaggacctggccgagaggtttcattttgtgtcctcc acgtcagagctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctctca ctgctggttcttgcagagtcaaagctgaagtcttggatcatcaagtatgggaggagagac tcagtagagctgcttctgcaaaactacatctctttcatagaaaacagcaagttctttgaa caatatgaagtgacataccagatcttgaaacagacagccgagatgtatgtcaaagccgat ggctcagtggaggaagctgagaatgtgatgaaattcatgaatgaaaccactgctcagtgg aggaacctctcagtagaagtcaggagtgtgcggagcatgctggaagaagtcattgctaac tgggaccgatacggcaatactgtggctagtcttcaggcttggctggaggatgctgagaaa atgctaaatcagtcagaacatgccaagaaggatttttttcgaaatttgcctcattggata cagcagcacgccgccatgaacgatgctggcaattttctgattgagacatgtgacgagatg gtttcccgcgatcttaaacagcagttactgctgctaaacgggcggtggagggagttgttt atggaagtcaagcaatatgcccgagccgacgagatggacagaatgaagaaggagtacaca gattgtgttactgccctgtctgactttgcaactgaagcccacaggaaactctctgagcca ctggaagtctcttttattaacgtgaagttattagttcaagacttggaggatattgagcag agggtgcctgtgatggacgctcagtataagataattacaaagacagcacatctcattacc aaagagagctcccaagaagaagcgaacgaaatgtttgcaaccatgtccaggctcagagag cagctaagcaaggtcaaagactgttactctccactcctttatgagtctcaacagctgttg ataccattggaggaattagaaaaacagatgacagccttttatgactcacttgggaaaatc aatgaaattttaacagttcttgagcacgaggcacaatccagctctctttttaaagagaaa catcaggaactattagcttgtcaagaaagctgtaagaaagccatgacccaaattgagaaa ggcagtcatagtgttcaaaagtttgtgaccttgagcaacgtgttaaagcattttgatcag acgaagctccagagacaggttgcggatgtgcacgttgcttttcagaatatggtaaagaaa actggcgattggaagaaacacgtggaaacgaacagccgcttgatgaagaaatttgaggag tctcgagcagagctggagaaggtgttgaggatcgcacaggagggcctggaggaaaagggg aatccagaagacctcctgaaaagacacacagagtttttcagtcagctggatcagagggtg ctcaacgcgttcctgaaggcttgtgacgaactcacggacatcctccccgagcaggagcag cagggcctgcaggaagctgtgaggaaactccacaaacagtggaaggatcttcaaggagaa gctccgtatcatttgcttcatctgaagattgaggtggagaagaacaggtttttagaatct gtggaagaatgcagagctgagctggaccgagagaccaagctggtgccccaggaaggcagt gagaagatcatcaaagagcacagggtcttcttcggtgacaaaggtcctcatcatgtctgt gagaaaaggctacagctcattgaagaactgtgtctgaaactcccggtccgggacccagtc cggaacacgcctgagacctgtcacgtgaccctcaaggagctcagagcggccattggcggc acctacgccaagctggtggagaacccggacaagtggaaggactacagtggcagaatttct gagttttcctgttggatctctacaaaggagacccaactgaaggggattaaaaacgaggcc atcgatactgccaaccatggagaggttaaacgtgctgtagaggagatcagagatggtgtt accaaaaagggtgagactctcagctggctgaaatccaggcttaaaattttgactgaagtt tcttctgagaatgaagcccaaaagcaaggagatgagctggcaaaattatctagttccttc aaggctctcgggactttgctgtcagaggttgaaaagatggtaagcaactttggagattgt gtccagtacaaagaaatagttaaaagttcccttgaagagttaattactggctctaaagaa atccaggaacaagccgagaagatcttggacactgaaaatctgtttgaagcacagcagcta ctccttcatcaccagcaaaagacaaagagaatctccgcaaagaagagggacgtgcagcag cagattgcgcaggctcggcagggagaaggtgggctgcccggccgggtccgagaggagctg cggaagctggagagcaccctggacagcgtggagcacagccgggagaagcaggaacgccgc atccaggtcacattaaggaaatgggagagatttgaaacaaacaaagagacagtggtcaga tacctttttcaaacaggttccagccatgagcgcttcttgagttttagcagtttggaaagc ttatcttcagaactggaacaaacaaaggagttttctaaacgaacagaaggtattgcagtc caggctgagaatcttgtgaaggaagcttccgagatcccactggggcccaggaataagcag ctgcttcagcagcaggccaagtcaatcaaagagcaagtcaaaaaattagaagacacactt gaagaagatattaaaaccatggaaatggtgaaaaacaagtgggatcattttggcaataat cttgagaccctgtctgtctggataactgagaaagaaaaagaactcaatgccttggaaact tcgtcatctgccatggacacacaaatccaccaaatcaaggtcacaattcaggaaatagaa 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tccatctccacgaagatggaggccatcgagatgaaactcagtgagagtctagagcatgga aggagtccagagagccagatggccgaacatcagtctctcccacaggccctgatggatgag attctcatgctgcaggaagagatcagcgagctccagtcggccctggcggaggagctggtg tccgagtccccggagtccgaccctgcggagcagctggccttgcagtccacgctcaccgtc ttagcagagcgcatgtccaccatcaagatgaaagcatctgggaaacgccagcttttggag gagaagttaaatgatcaactggaggaacagagacaggaacaggcccttcagaggtatctc tgtgaagccgaggagctggaccactggctcttgagcacgaaggccactctggacattgcc ctggggacacctgaggagcccatggatatggaggcccagctggtggactgccagaacatg ctggtggaaatagagcagaaggtggtggccttatcagagctctcagtgcacaatgaaaac ctgctgctggagggcaaggctcacacgaaggatgaggctgagcagctggcagtcaagctg aggaccctcaaggggaacctcctggagctgcagagagcgctgcatgacaagcagctcaac atccagcagggaacagcacaggagaaggaggagagcgatgctgacctggctgccactcag agccctggggttcaggaatggctggctcaagcccgtaccgcgtggacccaccagcgacag agcagtctccagcaacaaaaagagttggaacaggaattagcagagcagaagagcctcctc cggtcagtagccagtcgtggagaagaaatcctaacccaacactcagctgcagaaacctct ggtggtgctggcgaaaaacctgatgtgttatcccaggagttggggatggaaggggagaaa tcacctgctgaagaccagatgagaatgaaatgggaaagcctacatcaagaatttagtacc aagcagaaactacttcagaatgttctggaacaggaacaagagcaagtgctttacagcagg ccaaatcggctcctgtctggcgtaccactgtacaagggggacgggcaggcccaagataaa tccgcggtgacgtctttgctggatggactgaaccaggccttcgaggaggtttcatcccag ggcggggggacaaagaggcagaacattcacttggaacagaagttgtatgatggggtctca gctacctccacttggttggacgacgttgaggaacgtttatttgttgccacggcactttta ccggaagagacggaaacttgcctcttcaaccaagagactcttgccaaagatattaaggaa atgtctgaagaaatggataagaacaagatcttgttttcccaagcatttccagagaacggc gataaccgaggtgttattgaagacactttgggttgtcttttgggcaggttatctttgcta gactcagtagtaaatcagcgatgtcatcagatgaaggaaagacttcagcagattctaaat ttccagaatgatctgaaggtgctgtttacatcactcgctgaccacaaatacatcattctg cagaaactggcaactgtgttggaacagcctgtggcagagcaaatagaggcaatacagcag gctgaagatgggctgaaggaattggatgcaggaatcattgagttaaaaaggcgtgctgac aagctgcaggtggagcagccttccatgcaagaactctccagacttcaggacatgtatgat gagctgatggtgaccattggctcccggcggagtggtctgaaccagaatcttgctctcaag agtcagtatgaaagggccctgcaagatctggctgacctgctggacactggacgagagaag 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gttattcaaaaggatgaagagaatattaaaaattccatcggttacaaggccattcatgaa taccttcagaaatacaagggttttaagatcgacattaactgtaaacagctgacagttgat tttgtgaaccagtctgtgctacaaatcagcagtcaggatgtggaaagtaaacgcagtgat aagactgattttgctgagcagcttggagcaatgaataaaagttggcaaatcctgcagggt ctagtaactgagaagattcagctgttggaaggcttactggaatcttggtcagaatatgaa aataatgtacagtgtctgaaaacttggtttgaaacccaagaaaagagactaaaacaacaa catcgaattggcgatcaggcttcagttcagaacgcgatgaaagactgtcaggacctggaa gatttgattaaagcaaaagaaaaagaagtagagaaaattgagcagaatggacttgctttg attcagaacaagaatgaagaagtctctggcattgtcatgagcacgctgagggagctcaac caaacctgggcagacttagaccacatggttgagcaattaaagatcctgctgaagtccgtg cttgaccagtggagccaccacaaagcagcctttgatgagataaacagccgcctcacagag gccaggtactctctttcccgattccgcctgctgaccggctctttagaagctgtgcaagtt caggtagacaatcttcagaatcttcaagatgacctggaaaaacaggaaaagagcttacag aaatttggctctatcaccaaccagctattaaaagagtgtcacccacctgtgacagaaact cttaccaatacgctcaaagaagtcaacctgagatggaataacttgctggaagagattgct gagcagctgcactccagcaaggccctacttcagctctggcaacgatacaaggactactcc aaacagtgtgcttccacagttcaacagcaggagggtcgaaccaatgagctcctgaaggca gccacggacaaggacatcgctgacgacgaggttgccacatggattcaagactgcaacgac ctcctcaaaggactggagacagttaaggattccctttttgttctccatgaactgggagag caactcaagcagcaagtggacgcttcggctgcatcagccattcagtctgatcaagtgtct ttgagtcaacacttgggtgccctggaacaggctctttgcaagcagcagacgatgttacag gctggagttcttgactatgaaacctttaccaagagtttagaagctttggaggcctggata gtagaagctgaagaaatccttcaggcgcaagaccctagccactcatctgacctttccacc atccaggaaaggatggaagaacttaagggacagatgttaaaattcagcagcatggtccca gacttggatcgtctgaatgagctcgggtatcggttacccctgaatgataaagaaatcaaa aggatgcagaatctgaaccggcactggtctctgatctcctctcagactacagaaagattc agtaagttacagtcatttttgctacaacatcagactttcttggaaaaatgtgaaacatgg atggaattcctggttcaaacagaacaaaagttagcagtagagatttcgggcaattatcag catcttttggagcagcagagagcacatgagttgtttcaagcagagatgttcagtcgtcag cagattttgcactcgatcattattgatgggcagcgtcttctagaacaaggtcaagttgat gacagggatgaattcaacctgaagctgacacttctcagtaatcagtggcagggggtgatc cgcagggcccagcagaggcggggcatcatcgacagccagattcgccagtggcaacgctat 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cagctggataagaacatgagcagcctgaggacgtggctggcccacattgagtcagagctg gccaagccgatcgtctatgattcctgtgactcggaagaaatacagagaaagcttaatgag caacaggagcttcagagagacatagaaaaacacagcacgggcgtggcctctgtcctcaac ctgtgtgaggttctgctgcatgactgcgatgcctgtgccacggacgccgagtgtgattcc atccagcaggctacacggaacctggaccggcgatggaggaacatctgcgctatgtccatg gaaagaaggctcaaaattgaagagacgtggcgattgtggcagaagtttctggatgactat tctcgttttgaagagtggctgaagatttcagaaaggactgctgccttccccagctcttct ggggtgctctatacagttgccaaggaagaactaaagaaatttgaggctttccagcgacag gtccacgagtgcctgacccagctggagctgatcaacaagcagtaccgccggctggccagg gagaaccgcaccgactccgcctgcagcctgaagcagatggttcacgagggcaaccagaga tgggacaacctgcaaaagcgtgtcacctccatcttgcgccgactcaagcatttcattggc cagcgtgaggagtttgagactgcacgggacagcattctggtgtggctgacagagatggat ttgcagctcactaacattgagcatttttccgagtgtgatgttcaagctaaaataaagcag ctcaaggccttccagcaggaaatttcactgaaccacagtaagattgagcagatcatcgcc caaggagaacagctgatagagaagagcgagccgctggacgccgcggtcatcgaggatgag ctggatgagctccggcggtactgtcaggaggtctttgggcgcgtggaaagataccataag aagctgattcgcctgcctctcccagacgatgagcaggacctctctgaccgggagctggag ctggatgagtctgctgctctctcagacctccactggcgagacacctcggcagacagtgtg ctctccccccagccttcctccaacccctccctctcactggcccagcccctccggagcgag cggtcgggacgagacacccctgccagtgtggactccatccccctggagtgggaccatgac tatgacctcagtcgtgacctcgagtctgccgtgtccagaactttgccctccgaggacgaa gagggtcaggaggaaaaagatttctacctcaggggagctgttggcctatcagatgtagtg attcccgaaagtcctgaggcgtatgtaaaactcacagaaagtgcaatcagaaattcctct ggggatcccagtgccttagagtcgcagatccgacagctgggcaaagccctggatgacagc cgctttcacatgcagccaacagagactatcatccgcagcaaaactcccacaggaccagag ctagactccagctacagaggctatatgaaactgctcggtgaatgcagtggcagtatagac tcggtgaagagactggaacacgaactgaaggaggaggaggaccatttccccggctttgtt aacctgaacagcacagaaacgcaaacagccggtgtgattgaccgctgggagctcatccag gcacaggccctgagcaaggagctgaggatgaaacagaacccccagaggcggcagcagttc gactccgacctgagcagcacgctggcctggctccgggagaccgaggacgacctggagcag ctccggcgcctgcagctcagcaccgatatccagtccatcgcgctccagatccaaaagctc aaggagctccagaaagctgtggaccaccgcaaagccatcatcctctccatcaatctgtgc agctccgagttcactcaggctggccaagaggagagccaggatctgcaggatcgcttgtcc cagatgaatgggcgctgggaccgcgtgtgctccttgctggaggagtggcggggccttctc caggatgcactgatgcagtgccaggatttccatgaaatgagccatggtttgcttcttatg ctggagaacatcgacagaaggaaaaatgaaattgtccccattgattctaaccttgatgta gagatgcttcaggaccatcacaaacagctcacgcaaataagacgtgagctgttagatacc caactcaaagtggcctcactgcaagacatgtcttgccaactattggtgaatgctgaaggc acagactgtttagaagccaaagaaaaagtccatgtgattggaaatcggctcaaactcctc ttgaaggaggtcagtcgtcatatcaaggagctggagaagttattagacatgtcaagcagt cagcaggatctgtcttcctggtcttctgctgatgaactggacacctcaggatctgtgagt cctacatcgggaagaagtaccccaaacagacagagaacgccacgaggcaaatgtagtctc tcacagcctggaccctctgtcaacagtccacatagcaggtccataaaaggtggctccgat tcctccctttctgagccccagccagctcggtccggccgagccttcctgttccgggtcctc cgggcggctgtcccacttcagcttctgctgctgcttctcgtcgggctcgcctgccttgtg ccagtgtccgaggaagactacagctgtgccctctccaacaattttgcccgatcattccac cccatgctcagatacaccaacggcccgcctccactctga

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