Camelus ferus (Wild Bactrian camel): 102520718
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Entry
102520718 CDS
T02979
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
cfr
Camelus ferus (Wild Bactrian camel)
Pathway
cfr05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
cfr00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102520718 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
cfr01002
]
102520718 (BACE1)
Enzymes [BR:
cfr01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
102520718 (BACE1)
Peptidases and inhibitors [BR:
cfr01002
]
Aspartic peptidases
Family A1: pepsin family
102520718 (BACE1)
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
102520718
NCBI-ProteinID:
XP_006175396
UniProt:
A0A8B6Y8M2
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All DBs
Position
33:12569338..12593198
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AA seq
501 aa
AA seq
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MAQALPWLLLWMGSGVLPAHGSQPGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcgctgccctggctcctgctgtggatgggctccggagtgctgcctgcccac
ggttcccagcccggcatccggctgcccctgcgaagcgggcttgggggggcccccctgggg
ctgcggctgccccgggagaccgacgaggagccagaggagcccggccggaggggcagcttt
gtagagatggtggacaacctgaggggcaagtccggtcaaggctactacgtggagatgacc
gtgggcagccccccacagacgctcaatatcctggtggacacaggcagcagtaactttgcc
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggcgtgtacgtgccctacacccagggcaagtgggagggggag
ctgggcactgacctggtgagcatccctcatggccccaacgtcactgtgcgtgccaacatc
gctgccatcactgaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
gggctggcctatgctgagattgccaggcctgatgactccctggagccattcttcgactcc
ctggtaaagcagacccacgtgcccaacctcttctccctgcagctctgtggcgctggcttc
cccctcaaccagtcagaagtgctggcctcggttggagggagcatgatcatcgggggtatc
gaccactcgctgtacacaggcagcctctggtacacacccatccggcgggagtggtactac
gaggtgataattgtgcgggtggagatcaatggacaggatctgaaaatggactgcaaggag
tacaactacgacaagagcatcgttgacagtggtaccaccaaccttcgtctgcccaagaaa
gtgtttgaagctgctgtcaagtccatcaaggctgcctcctcgacggagaagttcccagac
ggtttctggctaggggaacagctggtgtgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctccctctacctcatgggggaggtcaccaatcagtccttccgcatcacc
atccttccacagcaatacctgcggccagtggaagacgtggccacgtcccaagacgactgt
tacaagttcgccatctcccagtcatccacaggcactgtcatgggagctgtcatcatggag
ggcttctacgttgtctttgatcgggcccggaaacgaatcggctttgccgtcagtgcttgc
cacgtgcacgatgagttcaggacagcagcggtggaaggcccttttgtcaccccggacatg
gaagactgtggctacaacatcccacagacagacgagtcgaccctcatgaccatagcctat
gtcatggctgccatctgcgccctcttcatgctgccgctctgcctcatggtgtgtcagtgg
cgctgcctccgctgcctgcgccatcagcacgatgactttgctgacgacatctccctgctg
aagtga
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