Camelus ferus (Wild Bactrian camel): 102524296
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Entry
102524296 CDS
T02979
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
cfr
Camelus ferus (Wild Bactrian camel)
Pathway
cfr00220
Arginine biosynthesis
cfr00330
Arginine and proline metabolism
cfr01100
Metabolic pathways
cfr04020
Calcium signaling pathway
cfr04022
cGMP-PKG signaling pathway
cfr04066
HIF-1 signaling pathway
cfr04071
Sphingolipid signaling pathway
cfr04151
PI3K-Akt signaling pathway
cfr04370
VEGF signaling pathway
cfr04371
Apelin signaling pathway
cfr04611
Platelet activation
cfr04915
Estrogen signaling pathway
cfr04921
Oxytocin signaling pathway
cfr04926
Relaxin signaling pathway
cfr04931
Insulin resistance
cfr04933
AGE-RAGE signaling pathway in diabetic complications
cfr05415
Diabetic cardiomyopathy
cfr05417
Lipid and atherosclerosis
cfr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfr00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
102524296 (NOS3)
00330 Arginine and proline metabolism
102524296 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
102524296 (NOS3)
04371 Apelin signaling pathway
102524296 (NOS3)
04066 HIF-1 signaling pathway
102524296 (NOS3)
04020 Calcium signaling pathway
102524296 (NOS3)
04071 Sphingolipid signaling pathway
102524296 (NOS3)
04022 cGMP-PKG signaling pathway
102524296 (NOS3)
04151 PI3K-Akt signaling pathway
102524296 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102524296 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
102524296 (NOS3)
04921 Oxytocin signaling pathway
102524296 (NOS3)
04926 Relaxin signaling pathway
102524296 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102524296 (NOS3)
05418 Fluid shear stress and atherosclerosis
102524296 (NOS3)
05415 Diabetic cardiomyopathy
102524296 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
102524296 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
102524296 (NOS3)
Enzymes [BR:
cfr01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
102524296 (NOS3)
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Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DEC-1_N
Motif
Other DBs
NCBI-GeneID:
102524296
NCBI-ProteinID:
XP_032339034
UniProt:
A0A8B8TA06
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All DBs
Position
7:complement(5508856..5526922)
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AA seq
1200 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPAAPAPEPSRAPAPAPPPAPDHSPPLTRPP
EAPKFPRVKNWEVGSIAYDTLSAQSQQDGPCTPRRCLGSLVFPRKLPGRPSQGPPPAEQL
LSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPR
CVGRIQWGKLQVFDARDCGSAQEMFTYICNHIKYATNRGNLRSAITVFPQRTPGRGDFRI
WNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELF
ALPPELVLEVPLEHPTLEWFATLGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIG
TRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAA
TASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPDPWKGS
ATKGVGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYASETGRAQSYAQQLGRLFR
KAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRP
EQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAF
ARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGKDAKAAAQDI
FSPRRSWKRQRYRLSVQAESLQLLPGLIHVHRRKMFQATVRSVENLQSSKSTRATILVRL
DTGGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPTEPVAVEQLEKGSPGGPPPC
WVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPSEQQELETLSQDPRRYEEW
KWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSANPGEIHLTVAVLAYR
TQDGLGPLHYGVCSTWLSQLKTGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRG
FWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSREPDS
PKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELDEAG
DVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDLPGPDTPGS
NT seq
3603 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacctgaagagcgtgggccaggagcccgggccgccctgcggcctggggctgggg
ctgggcctcgggctgtgtggcaagcagggcccggccgccccagcacctgagcccagccgg
gcaccagcacctgcacccccaccggcgccagaccacagccccccgcttacccggcctcca
gaggcgcccaagttccctcgtgtgaagaactgggaggtgggaagcatcgcctacgacact
ctgagtgctcagtcacagcaggacgggccctgtaccccccgacgctgcctgggctccctc
gtatttccacggaaactgccaggccggccctcccagggccctccacccgctgagcagctg
ctgagccaggcccgggatttcatcaaccagtactacagctccatcaagaggagtggttcc
caggctcacgagcagcggcttcaggaggtggaagctgaggtggcagccacggggacctac
cagcttcgggagagcgagctggtgttcggggccaagcaggcctggcgcaacgctccccgc
tgtgtgggccggatccagtgggggaagctgcaggtgtttgatgcccgggattgcggctct
gcacaggagatgttcacttacatctgcaaccacatcaagtatgccactaaccggggcaac
cttcgctcggccatcacagtattcccccagcgcactccgggccgtggagacttccgaatc
tggaacagccagctggtgcgctacgcaggctacaggcagcaggatggctccgtgcggggc
gatccagccaacgtggagatcactgagctctgtatccagcatggctggaccccaggaaac
ggtcgctttgatgtgctgcccctgctgctccaggccccagatgagcctccagaactcttt
gctctgccccccgagctggtccttgaggtgcccctggagcacccaacgctggagtggttt
gcaaccctgggcctgcgctggtacgccctcccggcagtgtccaacatgctgctggaaatt
gggggcctggagttccctgcggcccccttcagcggctggtacatgagcactgagatcggc
actcggaatctgtgcgatcctcaccgctacaacatcctggaggatgtggccgtctgcatg
gacctggatacccggaccacctcgtccctctggaaagacaaggctgcagtggaaatcaac
ttggctgtgctgcacagttatcagctggccaaagtgaccatcgtggatcaccacgcagcc
acggcctccttcatgaagcacctggagaatgagcagaaggcgaggggaggctgccctgcc
gactgggcctggatcgtgccccctatctcgggcagcctcacacctgtcttccatcaggag
atggtcaactatgtcctgtcccctgccttccgctaccagccagacccctggaaggggagt
gcgaccaagggcgtcggcatcaccagaaagaagacctttaaggaagtggccaacgcagtg
aagatctctgcctcactcatgggcaccgtgatggcgaagcgagtgaaggcaacaattctg
tatgcctccgagactggccgggcccagagctacgcgcagcagctggggaggcttttccgg
aaggctttcgacccccgggtcctgtgcatggatgagtatgatgtggtgtccctggagcat
gagactctggtgttggtggtgaccagcacatttgggaatggcgatccgcccgagaatgga
gagagctttgcagcagccctgatggagatgtcaggcccctacaacagctcccctcggccg
gaacaacacaagagttacaaaatccgcttcaacagtgtctcctgctcagacccactggtg
tcctcctggcggcggaaaagaaaggagtccagcaacacagacagtgcaggggcactgggg
accctcaggttctgtgtgttcgggctgggctcccgggcgtacccccacttctgcgccttt
gctcgtgcggtggacacacggctggaagagctgggtggggagcggctcctgcagctgggc
cagggcgacgagctgtgtggccaggaggaggccttccgcggctgggcccaggctgccttc
caggcctcctgtgagacgttctgcgttggaaaagatgccaaggccgctgcccaggacata
ttcagccccagacggagttggaaacgccagaggtaccgactgagtgtccaggccgagagc
ctccagctgctgccaggcctgatccacgtgcacaggcggaagatgttccaagctacagtc
cgctcagtggaaaacctgcaaagcagcaagtccacccgggccaccatcctggtgcgcctg
gacactggaggccaggaggggctccagtaccagccaggagaccacataggcatctgcccg
cccaaccggccgggcctcgtggaggcgctgctgagccgtgtggaggacccgccgccgccc
accgagcctgtggcagtggagcagctggagaagggcagccctggtggacctcctccctgc
tgggtgcgggatccccggctgcccccgtgcacgctgcgccaggctctcaccttctttctg
gacatcacttccccgcccagccctcaacttcttcgactgctcagcaccctagccgaagag
cccagcgaacagcaggagcttgaaaccctcagccaggacccccggcgctatgaggagtgg
aagtggttccgctgccccacgctgttggaggtgctggagcagtttccatctgtggcactg
cctgccccactgctcctcacccagctgcccctgctccagccccggtactactcggtcagt
tcagcacccagcgccaatccaggagagatccacctcacagtcgccgtgctggcatacagg
acacaagatgggctgggtcccctgcactacggggtctgctccacatggctgagccaactc
aagactggagaccctgtgccctgcttcatcagaggggctccctccttccggctgccacct
gatcccagcttgccctgcatcctggtgggccctggcactggcatcgccccctttcgagga
ttttggcaggagcggctgcatgacattgagagcaaagggctgcaacccgcccccatgacc
ttggtgttcggctgccgatgctcccagctcgaccatctctaccgtgacgaggtgcaggat
gcccagcagcgcggggtgtttggccgcgtcctgaccgccttctcccgggaacccgacagt
cctaagacctatgtgcaggacatcttgcggacagagcttgctgccgaggtgcatcgcgtc
ctctgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggcaaccaacgtc
ctgcagaccgtgcagcgcatcttggcaacggagggcgacatggagctggacgaggccggc
gacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacatttttgggctcacg
ctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcaggagcgg
catctccggggcgcagtgccctgggcgttcgacctgccgggaccagacacccctggctcc
tga
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