KEGG   Clarias gariepinus (North African catfish): 128519258
Entry
128519258         CDS       T10780                                 
Symbol
plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cgar  Clarias gariepinus (North African catfish)
Pathway
cgar00562  Inositol phosphate metabolism
cgar01100  Metabolic pathways
cgar04020  Calcium signaling pathway
cgar04070  Phosphatidylinositol signaling system
cgar04081  Hormone signaling
cgar04082  Neuroactive ligand signaling
cgar04261  Adrenergic signaling in cardiomyocytes
cgar04270  Vascular smooth muscle contraction
cgar04310  Wnt signaling pathway
cgar04371  Apelin signaling pathway
cgar04540  Gap junction
cgar04621  NOD-like receptor signaling pathway
cgar04912  GnRH signaling pathway
cgar04916  Melanogenesis
Module
cgar_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cgar00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    128519258 (plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    128519258 (plcb3)
   04371 Apelin signaling pathway
    128519258 (plcb3)
   04020 Calcium signaling pathway
    128519258 (plcb3)
   04070 Phosphatidylinositol signaling system
    128519258 (plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    128519258 (plcb3)
   04081 Hormone signaling
    128519258 (plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    128519258 (plcb3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    128519258 (plcb3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    128519258 (plcb3)
   04916 Melanogenesis
    128519258 (plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    128519258 (plcb3)
   04270 Vascular smooth muscle contraction
    128519258 (plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cgar04131]
    128519258 (plcb3)
Enzymes [BR:cgar01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     128519258 (plcb3)
Membrane trafficking [BR:cgar04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    128519258 (plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    128519258 (plcb3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PH_14 PLCB1-4-like_EFh C2 EF-hand_like Pterin_4a Legum_prodom
Other DBs
NCBI-GeneID: 128519258
NCBI-ProteinID: XP_053348905
LinkDB
Position
1:complement(27062436..27134847)
AA seq 1240 aa
MAGAKPGVHTLQLKPVCVPELLKAGSKFIKWDEEPNNGAMTQVTMKVDPEGFFLFWISPN
GETDIVDISHIRDTRYGKFAKIPKDSKICDRLGLVKGEIRENLMPVTIVYGNDLVNITFL
NFLAIEEGTAKVWTEELLKLATNLLSLNASRSTFLRKAWTKLTLHVNQDGRIPLKHIIKM
FSDKKRVETALEQCDLIVNKAEGIKLKDFTWEKFQSFLNKLCLRSEIDRIFVELGSKGKP
FLSLDQMTDFLNRKQRDPRLNEVLYPPLKREQVRQLMEKYDTNTRQLERDQISLMSFSKY
LESDENAVVPSERFDVMDDMTQPLSHYFINSSHNTYLTMGQLTGLSSVEMYRQVLLTGCR
CIELDCWKGRPPEEDPIITHGFTMTTEIPFKEVIEAIAESAFKASPYPLILSFENHVDSA
IQQEKMAECCRNIFGDALLIDPLEKYPLIPGQPLPSPQDLMGKILIKNKKRHYYHIRDRF
TANGGSISRKEGADEQASSLNDASLPEGETSQIMSNGGEKLAEKMSKDTRKSIDRGDGDS
EEEEEEEPVTDPKKHHSDEGTAYSEATATEEMSTLVNYIEPVKFKSFRWASERRKYYEMS
SFVETRGMDALKSFPIDFVEYNKNQLSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQT
LDLPMQLNMGVFEYNGRSGYLLKPEFMIRTDKHFDPFTEEIVDGIVANTVKIKIVSGQFL
TDKKVGVYVEADMFGLPTDTKRKYRTKTSNNSMDPVWEEEPFVFLKVVLPTLASLRVAVF
EENGKFIGHRILPVVALRPGYHYINLKNELNQPLLFASLFVYTEVQDYIPNEHQEYAEAL
TNPIKHVLDQRERQLAVLMEDNDDISKQVLVKSEQGEKPDFSLVSNEFPFALPSPTLPPL
VADVLTAPAPKEDLVITVLTAISPQSIDELRQEKSYVKLYKKQCKELKELHKKHLKKLWS
LGKEQKTRSNQLNSDIQRRKSQVEKKLRLSIKKNEPAEPVRTELSNLEMELEKRTVQLRE
WQMQELLELRKKQHKLEREKKFVHFEESFKKLKVVAEECQTTQIKKLKDICDREKREMQM
ILERKRLNSIFEARKGDREKAEAEMNEINRKHIQESVNSLRKLDEAQVKRQELLKTQQKE
ILLKIDEDQPLQRLHLERECDAELERLPEEIRRYLQGELEGKGLRNDALYSHLPNSDSSG
SGPPSNCSTPPFNSPNHSTASLGDSSSSSTITTESESTVI
NT seq 3723 nt   +upstreamnt  +downstreamnt
atggccggggcgaaaccgggagtgcacacgctccagctcaaacccgtgtgcgtgcccgag
ctcctgaaagcgggaagcaagtttatcaaatgggatgaggagcccaacaatggcgcgatg
actcaggtcaccatgaaagtggaccctgaaggattcttccttttctggattagcccaaac
ggggagacggatattgtggacatcagccatatcagagacaccagatatgggaagtttgcc
aagataccaaaggactcaaaaatatgtgatcgtctgggcttggtcaaaggagagatccgc
gagaaccttatgccagtaacaattgtctatggcaacgacctggtcaacatcacctttctc
aacttcctggctattgaggaggggactgccaaggtgtggacagaagagctgttaaaactt
gccacaaacttactgtccctaaatgcctcacgtagcaccttcttacgcaaggcatggacc
aagctaacacttcatgtcaaccaagatgggagaatcccactaaagcatattataaagatg
ttctctgacaagaagcgagtggagacagcgctggagcagtgcgacctcatagttaacaag
gcagaagggatcaagctgaaggacttcacctgggaaaagttccagagcttcttaaacaaa
ctctgcctgaggtctgagatcgaccgcatctttgtggaacttggctctaaagggaagccc
tttctatccctggatcagatgacggacttccttaaccgtaagcaaagagacccacggctg
aatgaggtgctctacccaccccttaagcgagagcaggtacgacagctcatggaaaaatat
gacactaacacccggcagctggaaagagaccaaatctcgctgatgagtttcagtaaatat
ctggaatcagatgaaaatgcagtggttccctccgagaggttcgacgtcatggacgatatg
acccagccgctgtctcattattttatcaactcttcacacaacacctacctcacaatgggt
cagttaacaggtttatcctcggtggaaatgtacagacaggttttgctcaccggatgtcgc
tgtatcgagctggactgctggaaaggtcgtccacccgaagaagaccccattatcactcac
ggcttcaccatgacaaccgaaatcccctttaaggaagtgattgaagccattgctgagagt
gcctttaaagcctctccttaccccctcatcctctccttcgaaaatcatgttgactccgca
attcagcaagaaaagatggcagaatgctgccgcaacatattcggtgatgcgttgctcatc
gatcctttagagaagtacccgctgatcccaggtcagccattgcccagtcctcaggatctg
atggggaaaatcctgataaaaaacaagaaaagacattactatcatatcagggatcgtttc
acggctaatggaggcagcatcagccgcaaggagggagcagacgagcaggcctcatctctc
aacgatgcttcattgcctgaaggcgagacgagtcagattatgtccaatgggggtgagaag
cttgcggagaagatgagcaaagacacacgcaagtctattgatcggggagatggagatagt
gaggaagaggaagaggaagagccagtgacagatcccaaaaagcaccattctgatgaggga
acagcatacagtgaagccactgctacagaagagatgtccacgctggtaaactacatcgaa
ccagtcaaattcaaatccttcagatgggcatccgaaaggagaaagtattacgaaatgtcg
tcctttgttgagaccagaggcatggacgccctgaaaagtttccccattgattttgtggaa
tacaataagaatcagttgagtcggatctatcccaaaggcacacgtgtggactctagtaat
tacatgcctcagctcttctggaatgtaggctgccagatggtggcgctaaacttccaaact
cttgatttgcccatgcagctaaacatgggtgtgtttgagtataacgggcgtagcgggtac
ctgctcaagcctgagttcatgattcgtacagataaacactttgaccctttcactgaggaa
atagtggatggcattgtggctaacacggtcaagatcaagattgtgtctggtcagtttctg
actgataaaaaggttggtgtttatgttgaggcggacatgttcgggctgcccactgacacc
aagaggaagtatcgcaccaaaacctctaacaactcaatggacccagtctgggaggaagag
cctttcgtctttcttaaggtggtgttacccacactagcatcacttagagtagctgtcttt
gaagagaatgggaagttcataggccatcggatcttaccagtggtggctttacgcccagga
taccattacattaatctgaagaatgagctcaatcagccactgctttttgcctcgctcttt
gtatacactgaagttcaagactacattcccaatgagcaccaagagtatgcagaggctctg
accaatccaatcaaacatgtgctggatcagagagagaggcagctagctgtgctcatggag
gataacgacgacatcagtaagcaagtacttgtaaagtcagaacaaggagagaaaccagat
ttcagtcttgtatctaatgagttcccattcgctttgccatccccaaccctcccacctttg
gtggcggatgtactgactgctccagccccaaaagaggacctggtcatcactgtattaaca
gcgatcagtccccagtccattgatgagctgaggcaggagaagtcctatgtcaagttgtac
aagaaacagtgcaaagaactgaaggagcttcacaagaaacacctcaaaaagctgtggtcc
ctcggcaaggagcagaagacgaggagtaaccagctgaactcggacatccagaggcgcaag
agtcaagtggagaaaaagctgcgactcagcataaagaaaaatgagcccgctgagcctgtg
aggactgagctgagtaatctggagatggagctggagaagaggacagtgcagctaagagag
tggcagatgcaggagctactcgaactgcgaaagaaacaacacaagctggaaagagaaaag
aagttcgttcactttgaagagtcatttaagaaactaaaagtagttgctgaggaatgccag
acaacacagatcaagaaactcaaggacatatgtgaccgagagaagagggaaatgcagatg
attttagaaagaaaacggctgaacagcatctttgaggccagaaagggagacagagagaaa
gccgaggcggaaatgaatgaaataaatagaaaacatattcaggagtcggtgaactcactg
cgcaagttggatgaagctcaggtgaaacgccaggagttgctgaagacccagcagaaagaa
atcctactgaaaatagacgaggatcaaccgctgcaacggctacatttggagcgcgaatgc
gacgcagagctcgagcggttacccgaggagatccgccgctacctgcagggcgagctagag
ggcaaaggtctgcgcaacgatgccctgtacagccacctgcccaacagcgacagctctggc
tcaggtccaccctccaactgcagcacgccccctttcaactcgcctaatcacagcacagcc
tcgctcggcgactcctcatcctcaagcaccatcacgaccgaatcggagtccacggtcatc
tga

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