Clarias gariepinus (North African catfish): 128527427
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Entry
128527427 CDS
T10780
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
cgar Clarias gariepinus (North African catfish)
Pathway
cgar00280
Valine, leucine and isoleucine degradation
cgar00640
Propanoate metabolism
cgar00785
Lipoic acid metabolism
cgar01100
Metabolic pathways
cgar01210
2-Oxocarboxylic acid metabolism
Module
cgar_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cgar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
128527427 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
128527427 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
128527427 (bckdha)
Enzymes [BR:
cgar01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
128527427 (bckdha)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DUF6194
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
128527427
NCBI-ProteinID:
XP_053355746
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Position
7:complement(32189008..32201801)
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AA seq
449 aa
AA seq
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MAAVRRVQGLWGLGVRAIRQHSALKTSSVLQQRAFRLDVARRQQTFDSSMEKPQFPGASA
EFVDHLEFIQPNVISGIPVYRVMDRQGQIINPSEDPQLSKDTVLNFYQKMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHIGSAAALDSTDLVFGQYREAGVLMYRGFPLDLFMAQCY
GNADDLGKGRQMPVHYGTRDLNFVTISSPLATQLPQAAGAAYAIKRENSNRVVICYFGEG
AASEGDAHAGFNFSATLECPIIFFCRNNGYAISTPTHEQYRGDGIAARGPGYGMLSIRVD
GNDVFAVYNATREARRRAIAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYMTARSWWGEDEERAWRKQSRKLVMEAFEKAERRLKPNPELLFTDIYNEMTPG
LAKQKESMLRHIQQYKEHYPLDLYEKIEN
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgtgagacgcgtgcaggggctgtggggactcggtgtccgtgcaatccgtcaa
cactcagccctgaaaacctccagcgtcctgcagcagagagctttccgcctcgatgtcgct
cggagacagcagacgtttgattcatccatggagaagcctcagttcccaggagcctcagcc
gagttcgtcgatcacctggagttcatccagcccaacgtgatctcaggaatccctgtgtat
cgagtcatggatagacagggccagatcatcaacccgtctgaagatccacagctctccaaa
gatacagtgttgaacttctaccagaagatgacgctcctcaacacgatggatcgcatcctg
tacgagtctcagaggcagggtcgtatctctttctacatgaccaactacggtgaagagggc
actcacattggaagtgctgcagctctcgactccaccgacctggtgtttggacagtatcga
gaggcaggagtgctgatgtaccgcggtttccctctggacctgtttatggcgcagtgctac
ggtaatgcggatgacttggggaagggcaggcagatgccggtgcactacggtaccagagac
ctcaacttcgtgaccatctcgtctcctctggccacgcagcttcctcaggcggcgggagca
gcatatgctataaagcgggagaacagtaaccgtgtggtgatctgttactttggtgaggga
gccgcgagtgaaggagacgcccatgccggcttcaacttttccgccactctggagtgtcca
atcatattcttctgccgcaataacggctatgctatctccacccccactcacgagcagtac
cgcggcgacggcattgctgctcgaggtccgggctacggcatgttgtcaatccgtgtggac
ggtaacgatgtgtttgcggtgtacaacgctaccagggaagcgcggcgtagagcgattgcc
gagaaccaacctttcctcatcgaggccatgacctacaggattggccaccatagcacgagc
gacgacagctcggcttaccgttcagtggacgaggtgaactactgggacaagcaggaccac
cccatctctcgtctgcgccactacatgaccgcgcgcagctggtggggtgaggacgaggag
cgtgcgtggaggaagcagtcgcgcaagctcgtcatggaagccttcgaaaaggccgagcgg
cgtctcaaaccgaacccggagttattgttcaccgacatctacaacgagatgactccaggc
ctggccaaacagaaagagtccatgttaaggcacatacagcagtataaagagcactaccca
ctcgatctgtacgagaagatcgagaattag
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