Corynebacterium glutamicum ATCC 13032 (Bielefeld): cg0303
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Entry
cg0303 CDS
T00244
Symbol
leuA
Name
(GenBank) 2-ISOPROPYLMALATE SYNTHASE
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cgb
Corynebacterium glutamicum ATCC 13032 (Bielefeld)
Pathway
cgb00290
Valine, leucine and isoleucine biosynthesis
cgb00620
Pyruvate metabolism
cgb01100
Metabolic pathways
cgb01110
Biosynthesis of secondary metabolites
cgb01210
2-Oxocarboxylic acid metabolism
cgb01230
Biosynthesis of amino acids
Module
cgb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cgb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
cg0303 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
cg0303 (leuA)
Enzymes [BR:
cgb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
cg0303 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
PP_kinase_C
Motif
Other DBs
NCBI-ProteinID:
CAF18819
UniProt:
P42455
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All DBs
Position
complement(266152..268002)
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AA seq
616 aa
AA seq
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MSPNDAFISAPAKIETPVGPRNEGQPAWNKQRGSSMPVNRYMPFEVEVEDISLPDRTWPD
KKITVAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVQMGFKEIEVGFPSASQTDFDFV
REIIEKGMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRMDK
VQVKKLATDAAELIKTIAQDYPDTNWRWQYSPESFTGTEVEYAKEVVDAVVEVMDPTPEN
PMIINLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVGAAELGYMAGA
DRIEGCLFGNGERTGNVCLVTLALNMLTQGVDPQLDFTDIRQIRSTVEYCNQLRVPERHP
YGGDLVFTAFSGSHQDAVNKGLDAMAAKVQPGASSTEVSWEQLRDTEWEVPYLPIDPKDV
GRDYEAVIRVNSQSGKGGVAYIMKTDHGLQIPRSMQVEFSTVVQNVTDAEGGEVNSKAMW
DIFATEYLERTAPVEQIALRVENAQTENEDASITAELIHNGKDVTVDGRGNGPLAAYANA
LEKLGIDVEIQEYNQHARTSGDDAEAAAYVLAEVNGRKVWGVGIAGSITYASLKAVTSAV
NRALDVNHEAVLAGGV
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgtctcctaacgatgcattcatctccgcacctgccaagatcgaaaccccagttgggcct
cgcaacgaaggccagccagcatggaataagcagcgtggctcctcaatgccagttaaccgc
tacatgcctttcgaggttgaggtagaagatatttctctgccggaccgcacttggccagat
aaaaaaatcaccgttgcacctcagtggtgtgctgttgacctgcgtgacggcaaccaggct
ctgattgatccgatgtctcctgagcgtaagcgccgcatgtttgagctgctggttcagatg
ggcttcaaagaaatcgaggtcggtttcccttcagcttcccagactgattttgatttcgtt
cgtgagatcatcgaaaagggcatgatccctgacgatgtcaccattcaggttctggttcag
gctcgtgagcacctgattcgccgtacttttgaagcttgcgaaggcgcaaaaaacgttatc
gtgcacttctacaactccacctccatcctgcagcgcaacgtggtgttccgcatggacaag
gtgcaggtgaagaagctggctaccgatgccgctgaactaatcaagaccatcgctcaggat
tacccagacaccaactggcgctggcagtactcccctgagtccttcaccggcactgaggtt
gagtacgccaaggaagttgtggacgcagttgttgaggtcatggatccaactcctgagaac
ccaatgatcatcaacctgccttccaccgttgagatgatcacccctaacgtttacgcagac
tccattgaatggatgcaccgcaatctaaaccgtcgtgattccattatcctgtccctgcac
ccgcacaatgaccgtggcaccggcgttggcgcagctgagctgggctacatggctggcgct
gaccgcatcgaaggctgcctgttcggcaacggcgagcgcaccggcaacgtctgcctggtc
accctggcactgaacatgctgacccagggcgttgaccctcagctggacttcaccgatata
cgccagatccgcagcaccgttgaatactgcaaccagctgcgcgttcctgagcgccaccca
tacggcggtgacctggtcttcaccgctttctccggttcccaccaggacgctgtgaacaag
ggtctggacgccatggctgccaaggttcagccaggtgctagctccactgaagtttcttgg
gagcagctgcgcgacaccgaatgggaggttccttacctgcctatcgatccaaaggatgtc
ggtcgcgactacgaggctgttatccgcgtgaactcccagtccggcaagggcggcgttgct
tacatcatgaagaccgatcacggtctgcagatccctcgctccatgcaggttgagttctcc
accgttgtccagaacgtcaccgacgctgagggcggcgaggtcaactccaaggcaatgtgg
gatatcttcgccaccgagtacctggagcgcaccgcaccagttgagcagatcgcgctgcgc
gtcgagaacgctcagaccgaaaacgaggatgcatccatcaccgccgagctcatccacaac
ggcaaggacgtcaccgtcgatggccgcggcaacggcccactggccgcttacgccaacgcg
ctggagaagctgggcatcgacgttgagatccaggaatacaaccagcacgcccgcacctcg
ggcgacgatgcagaagcagccgcctacgtgctggctgaggtcaacggccgcaaggtctgg
ggcgtcggcatcgctggctccatcacctacgcttcgctgaaggcagtgacctccgccgta
aaccgcgcgctggacgtcaaccacgaggcagtcctggctggcggcgtttaa
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