KEGG   Cupriavidus gilardii: CR3_1323
Entry
CR3_1323          CDS       T04050                                 
Symbol
copS
Name
(GenBank) heavy metal sensor kinase
  KO
K07644  two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
Organism
cgd  Cupriavidus gilardii
Pathway
cgd02020  Two-component system
Brite
KEGG Orthology (KO) [BR:cgd00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    CR3_1323 (copS)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cgd01001]
    CR3_1323 (copS)
  09183 Protein families: signaling and cellular processes
   02022 Two-component system [BR:cgd02022]
    CR3_1323 (copS)
   01504 Antimicrobial resistance genes [BR:cgd01504]
    CR3_1323 (copS)
Enzymes [BR:cgd01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     CR3_1323 (copS)
Protein kinases [BR:cgd01001]
 Histidine kinases
  OmpR family
   CR3_1323 (copS)
Two-component system [BR:cgd02022]
 OmpR family
  CusS-CusR (copper tolerance)
   CR3_1323 (copS)
Antimicrobial resistance genes [BR:cgd01504]
 Gene sets
  beta-Lactam resistance modules
   Imipenem resistance, repression of porin OprD [MD:M00745]
    CR3_1323 (copS)
SSDB
Motif
Pfam: CusS HATPase_c HisKA HAMP HATPase_c_5 ZW10_C2
Other DBs
NCBI-ProteinID: ALD90556
LinkDB
Position
1:1562405..1563799
AA seq 464 aa
MTHRLSLTMRLTILFSLCSAVVLLGLGVLIWLAMDRHFATEDYVVLGDNIRLIEKIAQET
PAERLPQRLREMVDHHPGFVAQVQTAQGHKLYATKDFDFAIAFEAIPRELARDNTFVWQQ
GEQEYRGMRAQVGAADPRIAPLRVVVGMDTEIHAHFMHAFRRSLAFYTTLAVLASGLFGW
WAARRGLAPLRMMASRAKGVTANKLDARMPVEAVPVEMADLAITLNAMLERLQDDFRRLS
EFSSDLAHELRTPITNLMTQTHVVLSQPRDAAKYREVLASNAEELQRLGRMVSDMLYLAK
MEHGITLPNEEAINVADEVQALFEFYDALAEDKGVNLRLDGQAKITGDRLMLRRALSNLL
SNALRYTPSGKEIRVETREQGGSTSIVVENEGEEISPELLPSLFDRFFRADKSRTRAESE
SVGLGLSITQAIMFAHGGQISAESSEGTTRFILTFPRQRNAARS
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgacgcatcgcctgtccctgacgatgcgtctgaccatcctgttttcgctctgctctgcc
gtggtgctgctgggcttgggcgttctcatctggctggcgatggaccgccacttcgccacc
gaggattatgtggtgctcggcgacaatattcgcctgatcgaaaagatcgcgcaggaaacg
ccggccgagcgcttgccccagcggcttcgggaaatggtcgatcaccatcctggcttcgtc
gcgcaggtgcagaccgcacaaggccacaagctgtatgcgaccaaggacttcgattttgcg
attgctttcgaggcgattccgcgcgaattggcgcgtgacaataccttcgtctggcagcaa
ggcgagcaggagtatcgcggcatgcgcgcgcaggttggtgcggctgacccgcgcattgca
cctttgcgcgtcgtggtcggcatggacacggaaatccacgcgcacttcatgcatgcattt
cgtcgttcgctggccttctataccacattggcggtgctcgccagcggtctctttggttgg
tgggcggcgcgacgcgggctcgcacccctgcgcatgatggcctcacgcgccaagggcgtc
accgcgaacaaactggatgcgcgcatgccggtcgaagccgtgccggtcgagatggcagat
ctggcgatcacgttaaacgcgatgctggagcgactgcaggatgattttcggcggctctcg
gaattctcctccgatttggcgcatgagctgcgcacgcccatcaccaacctgatgacgcag
acgcatgtcgtgctatcgcagccgcgagatgccgccaaatatcgagaggtcctggcctcg
aatgccgaggaattgcagcggcttgggcgcatggtgtccgatatgctgtacttggccaag
atggagcacggcatcacactgccgaatgaggaagcgatcaacgtggctgatgaagtacag
gcgctgttcgaattctacgacgcgctggcagaggacaagggcgtcaatctacggcttgat
gggcaggcgaaaattaccggcgaccgtctgatgttacgccgagcgctcagcaatctgctc
tcgaacgctctacgctatacgccgtccggcaaagagatccgggtcgagacgcgcgagcag
ggcggcagcacgtcgatcgtagtcgagaatgagggcgaggaaatcagtcccgagttgctg
ccatcgctattcgaccgctttttccgtgccgacaaatcaaggacccgtgcggagtccgaa
agcgtgggactgggtctctccatcacgcaagccatcatgtttgcgcacgggggccagatt
tcggcggaatcgtcggaaggcactacgcgcttcattttgacgtttccccgccagcgaaac
gccgcccggagctag

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