Cricetulus griseus (Chinese hamster): 100689022
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Entry
100689022 CDS
T02813
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00790
Folate biosynthesis
cge01100
Metabolic pathways
cge01240
Biosynthesis of cofactors
cge01523
Antifolate resistance
cge04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100689022 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100689022 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100689022 (Fpgs)
Enzymes [BR:
cge01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
100689022 (Fpgs)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
100689022
NCBI-ProteinID:
NP_001230938
UniProt:
Q924L9
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Position
6:complement(144400412..144411911)
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AA seq
587 aa
AA seq
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MSWARTHLRSALSLAAVSARGATTEGAARRWLSAWPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRSDPQAQLEAMEVYLARSGLQVEDLNQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGKPISPELFTKHFWRLYHQLEEFKDDSHVAMPAYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGMDHTSLLGDTVEKIA
WQKGGIFKPGVPAFTVLQPEGPLAVLRDRAQQTSCPLYLCPPLEALEDGGLPLTLGLEGE
HQRSNAALALQLAHCWLEQQDHQDIRELKVSRPSMRWQLPLAPVFHPTSHMRHGLRDTEW
PGRTQVLRRGPLTWYLDGAHTTSSVQACVRWYCQSLQRSKHPSGGPEVYVLLFNSTGDRD
SAALLKLLQPCQFDYAVFCPNLTEVSSTENADQQNFTVTLDQVLLRCLQHQQHWSCLSEK
QASPDFLSSPSPEPGRPGSLQPALRPPHSTGTNSLVFSCISHALQWISQGRDPIFQAPSP
PRSLLSHPTASSGASILREAGAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggacgcacctgcgctcggctctgtccctggcagctgtttctgcgcgt
ggtgcaacgaccgagggcgcggcgcggcggtggttgagcgcgtggcccgcgcctcaggag
cccggcatggagtatcaggatgctgtgcgcatgctcaacaccctgcagaccaatgccagc
tacctggagcaggtaaagcgccaacggagtgaccctcaggcgcagctggaagccatggag
gtgtacttggcacggagtgggctgcaggtggaggacttgaatcagttaaacattatccat
gtcactgggaccaaaggaaagggctccacctgcgccttcactgaacgcatcctgaggagt
tatggcctgaagacaggcttctttagctctccccacctggtgcaggtgcgtgaacggatt
cgcatcaatgggaaacccatcagtcccgagctctttaccaagcacttctggcgcctctat
caccagctggaggagttcaaggatgacagccacgttgccatgcctgcttacttccgcttc
ctgacactcatggccttccatgtcttcctccaagaaaaggtggacctggcagtggtggaa
gtgggcattggtggggcttatgattgcaccaacatcatcagaaagccagtagtgtgtgga
gtgtcctctcttggcatggaccacaccagcctgctcggagacacggtggagaaaatagca
tggcagaaagggggcatcttcaagcctggtgtccctgccttcactgtgctacagccagaa
ggtcccctggccgtgctgagggatcgagcccagcagacctcatgtcctctgtacctgtgt
ccaccattagaagccctggaggatggtgggctgccgctgaccctgggcctggagggagag
caccagcggtccaatgcagccttagccttgcaactggcccattgttggctggagcagcag
gaccaccaggacatccgggagctgaaggtgtccaggccgagcatgcggtggcagctgcct
ctggcacctgtgttccatcccacttcccacatgagacatgggcttcgggacacagaatgg
cctggccggacacaggtattgcggcggggacctctcacctggtacctggatggcgcacac
accaccagcagtgtgcaggcctgtgtgcgctggtattgccagtcattgcagcgcagcaaa
caccccagtggtgggcctgaagtatacgtcttgctcttcaactccacgggtgacagggac
tctgctgccctgctgaagttgctgcagccctgccagtttgactacgctgtcttttgcccc
aacctgacggaggtgtcatccacagaaaatgcagaccagcagaacttcacagtgactctg
gaccaggtgctgctccgctgcctccaacaccagcaacactggagctgcctgagtgagaaa
caagccagccctgacttcctgagcagccccagcccagagcctggcaggccaggttccctg
cagccggcactgcgcccgcctcactctacgggcactaactcccttgtctttagctgtatc
tcccacgccttgcagtggatcagccaaggccgggatcccatctttcaggccccaagccct
ccaaggagcctcctcagccaccccacggccagtagtggggcaagcattctccgggaggct
ggtgccatccatgtactggttactggaagcctgcacctggtgggtggagtcctaaagctg
ctagagccctccctgtcccagtag
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