Cricetulus griseus (Chinese hamster): 100689304 Help Entry 100689304         CDS       T02813                                  Symbol Top2a Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism cge  Cricetulus griseus (Chinese hamster) Pathway cge01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:cge00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100689304 (Top2a)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:cge03032]     100689304 (Top2a)    03036 Chromosome and associated proteins [BR:cge03036]     100689304 (Top2a) Enzymes [BR:cge01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      100689304 (Top2a) DNA replication proteins [BR:cge03032]  Eukaryotic type   DNA Topoisomerases    100689304 (Top2a) Chromosome and associated proteins [BR:cge03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     100689304 (Top2a)   Centrosome formation proteins    Centriole proteins     100689304 (Top2a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  100689304 NCBI-ProteinID:  NP_001233667 UniProt:  P41515 G3I5N5 LinkDB All DBs Position 7:complement(112071654..112102887) Genome browser AA seq 1526 aa AA seqDB search MELSPLQPVNENMQMNKKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQM WVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN GKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTRFTVET ASKEYKKMFKQTWMDNMGRAGDMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVR RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNALKVVHEQVNPRWEVCL TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQI QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQELAFYSLPEFEEWKSS TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDR KEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDG LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLKFLYDDNQRVEPEWY IPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEE LASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH TDTTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILKD FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRG YDSDPVKAWKEAQQKVPDEEENEESDNENSDSVAESGPTFNYLLDMPLWYLTKEKKDELC KQRNEKEQELNTLKNKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKGGKAKGKKA QMSEVLPSPHGKRVIPQVTMEMKAEAEKKIRKKIKSENVEGTPTENGLELGSLKQRIEKK QKKEPGAMTKKQTTLAFKPIKKGKKRNPWSDSESDMSSNESNVDVPPREKDPRRAATKAK FTMDLDSDEDFSGSDGKDEDEDFFPLDTTPPKTKIPQKNTKKALKPQKSAMSGDPESDEK DSVPASPGPPAADLPADTEQLKPSSKQTVAVKKTATKSQSSTSTAGTKKRAVPKGSKSDS ALNAHGPEKPVPAKAKNSRKRKQSSSDDSDSDFEKVVSKVAASKKSKGENQDFRVDLDET MVPRAKSGRAKKPIKYLEESDDDDLF NT seq 4581 nt NT seq  +upstreamnt  +downstreamnt atggagttgtcgccgctgcagcctgtaaatgaaaatatgcaaatgaacaaaaagaaaaat gaagatgccaagaaaaggctgtctattgaaagaatctatcagaaaaaaacacaattggaa catatattgctccgcccagatacctacattggctctgtggaattagttacccagcaaatg tgggtttacgatgaagatgttggcattaactacagggaagtaacttttgttcctggtttg tataaaatctttgatgagattctagttaatgctgcagacaacaaacaaagggacccaaaa atgtcttgtattagagtcacaattgatccagaaaataatttaattagtatatggaataat ggaaaaggaattcctgttgttgaacacaaagttgagaaaatgtatgtcccagctctcata tttggacagctcttaacctctagtaactatgatgatgatgaaaagaaagtaacaggtggt cgaaatggttatggagccaaactgtgtaacatattcagcaccagatttactgtggaaact gccagtaaagaatacaagaaaatgttcaaacagacatggatggataacatggggagagct ggtgacatggaactcaagccctttaatggagaagattatacatgtattaccttccagcct gatttatcaaagtttaagatgcaaagccttgacaaagatattgttgcactgatggttaga agggcatatgatattgctggttccactaaagatgtcaaagttttccttaatggaaataag ctgccagtaaaagggttccgcagctatgtggatatgtatttgaaggataaattagatgaa actggtaacgcactgaaagtagtacatgaacaagtaaacccaaggtgggaagtgtgctta acaatgagtgaaaaaggctttcaacaaattagctttgtcaatagcattgctacttctaag ggtggcagacatgttgattatgtagctgatcagattgtgagtaaacttgttgatgtggtg aagaagaagaacaagggtggtgttgcagtgaaagcccaccaggtgaaaaatcacatgtgg atttttgtaaatgccttgattgaaaacccaacctttgactctcagacaaaagaaaacatg actttacaggccaagagctttggatcaacatgtcaattaagtgaaaaattcatcaaagct gcaattggctgtggtattgtcgaaagcatactaaactgggtgaagtttaaggcccaaatc cagttaaacaagaaatgttcagctgtaaaacataacagaatcaagggaatccccaaactt gatgatgccaacgatgcagggagtcgaaactccactgaatgtacacttatcctaactgag ggagactcagccaaaacactggcagtttcaggtcttggtgttgttggaagagataaatat ggggtatttcctcttagaggaaaaatactcaatgtgcgagaagcttctcataaacagatc atggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtataagaaaaac tatgaagatgaagattcattgaaaactcttcgttatgggaagataatgattatgacagat caggatcaagatggttcccatatcaaaggcttgctgatcaattttatccatcacaactgg ccctctcttctgcgtcatcgttttctagaggaatttattactcccattgtaaaggtgtct aaaaacaagcaagaattggcattctatagtcttcctgagtttgaagaatggaagagttct actccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcacatca aaggaagctaaagaatattttgcagatatgaaaagacatcgtattcagttcaaatactct ggacctgaagatgatgctgcaatcagcctggcctttagtaagaaacaggtcgatgatcga aaggaatggttgactcatttcatggaagatagacggcagcggaagttacttggccttcct gaggattatttgtatggacaaaccactacttacctgacgtataatgacttcataaacaag gaacttattctgttctcaaattctgataatgaaagatctatcccatctatggtagatggt ttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacggaatgacaagcgagaa gtgaaggttgcccagttagctgggtcagtggcagaaatgtcctcttatcaccatggtgag atgtcactgatgatgaccattatcaatttggctcagaattttgtgggtagtaataatttg aaccttttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattcagct agtcctcgatacatctttactatgctcagccctttgactcggttgttatttccaccaaaa gatgatcacacattaaagtttttatatgatgacaatcagcgtgttgaacctgaatggtac attcctattattcccatggtgctgataaatggcgctgagggaattggtaccgggtggtcc tgcaaaatccccaactttgatatccgtgaagtcgtaaataatatcagacgactgttggat ggagaagagcctctgcccatgctcccaagttacaaaaatttcaaaggtactattgaagag ctggcttctaatcagtatgtgattaatggagaagtagctattctaaattccacaaccatt gaaatctcagagcttcccatcagaacgtggactcagacttacaaagaacaggttctagaa cccatgttgaatggtactgagaagacaccccctcttataacagactatagggaatatcac acagacaccactgtcaagtttgtcataaagatgactgaagaaaaattagcagaggcagag agagtgggactacacaaagtcttcaaactgcagactagtctcacttgcaactctatggtg ctttttgaccatgtaggttgcttaaagaaatatgacactgtgttggatattctaaaagac ttctttgagctcaggcttaaatattatggattaagaaaagaatggcttctgggaatgctt ggtgcagaatctgctaaactgaataatcaagctcgttttatattagagaaaatagatggc aaaataatcattgaaaataaacctaaaaaagagctaattaaagttctaattcagagagga tatgattcagatcctgtaaaagcctggaaagaagctcagcaaaaggtcccagatgaagaa gaaaatgaagaaagtgacaatgaaaacagtgactctgtagcagaatctggaccgactttc aattaccttcttgatatgcccctttggtatctaaccaaagaaaagaaagatgaactgtgc aaacaaagaaatgaaaaggaacaagagctcaacacattaaagaacaagagtccatcagat ttgtggaaggaggatttggcagtttttattgaagaactggaggttgttgaagccaaggaa aagcaagatgaacaagtaggacttcctggaaaaggggggaaagcaaaagggaagaaagca caaatgtctgaagtcttgccttctcctcacggaaaaagagttattccccaagtgaccatg gagatgaaagcagaagcagagaagaaaattaggaagaaaattaagagtgaaaacgttgag ggcactcctactgagaatggtctggaactaggaagcttaaaacaaagaatagagaagaag cagaagaaagagccaggtgccatgacaaagaagcagactacattggcttttaagccaatc aaaaaagggaaaaagagaaacccctggtctgattctgaatcagatatgagcagtaatgaa agtaatgttgatgtccctccacgagaaaaggacccacgaagagctgcaacaaaagccaaa ttcacgatggatttggattcagatgaagatttctcaggttctgatggaaaggatgaagat gaagattttttcccactagatactactccacctaagaccaaaattccccaaaaaaatact aagaaagcactgaagccacaaaagagtgccatgtctggtgaccctgaaagtgatgaaaag gacagtgtgccagcttctccaggccctcctgctgctgacttgccagctgacactgaacag ttaaagccatcttccaaacagactgtggcagtgaagaagacagccaccaaaagccagtct tcaacatccactgctggtaccaaaaagagagctgtaccaaaaggaagcaaatcagattca gccttgaatgctcatggccctgaaaagcctgtgcctgccaaagccaagaacagccgcaaa aggaagcagtcctcttctgatgattctgactctgattttgagaaagtagtctccaaagtt gctgcaagcaagaaatccaagggagagaatcaggatttccgagtggacttagatgaaact atggttcctcgagcaaaatctggacgagcaaagaagcctatcaaatacctggaggagtca gatgatgatgatcttttctga

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