Cricetulus griseus (Chinese hamster): 100689446
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Entry
100689446 CDS
T02813
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00230
Purine metabolism
cge00670
One carbon pool by folate
cge01100
Metabolic pathways
cge01523
Antifolate resistance
Module
cge_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100689446 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100689446 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100689446 (Gart)
Enzymes [BR:
cge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
100689446 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
100689446 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
100689446 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp_4
RimK
LUD_dom
ATP-grasp_5
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
100689446
NCBI-ProteinID:
NP_001233634
UniProt:
B2ZA78
LinkDB
All DBs
Position
4:6136011..6156890
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTASSGKISNAAVSITDHTVLAQ
FCKDEKIEFVVVGPEAPLAAGVVEDLACAGVRCFGPTAQAAQLESSKKFAKEFMDRHGIP
TAQWKAFTKPEDACSFIMSANFPALVVKASGLAAGKGVIVAKNKEEACKAVQEIMQEKSF
GAAGETVVVEEFLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDQGPNTGGMGAYCPTP
QVPTDCLLKIKNTILQRTVDGMRQEGAPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLSTSLPVWLENHSAVTVVMASKGYPGAYAKGVEITGFPEA
QALGLQVFHAGTALKDGKVVTSGGRVLTVTAVGENLVSALEEAKKGLAAIKFEGAVYRKD
IGFRAVAFLQQPRGLTYKESGVDIAAGNMLVKKIQPLAKATSRPGCNVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSTTEAVVAGIAGACRQADCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
RLERITEGDVVVGVASSGLHSNGFSLVRKIVARSSLQYSSPAPGGHGDQTLGDLLLTPTR
IYSHSLLPIIRSGRVKALAHITGGGLLENIPRVLPKKLGVDLDACTWRIPKVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKDQTDQILHDIRQRQEEAWVIGSVVACPEDSPRVRVKN
LMEAMQMNGAVVSNGFLRSHFPAQQKKSRVAVLISGTGSNLQALIDSTKDAKSSTHIVVV
ISNKAGVAGLDKAEKAGIPTRVINHKLYKSRVEFDNAVDQVLEEFSVDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRDDSVATLSERVKAAEHRVFPAALQLVASGAVRLGKDGSVHWAREQ
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagttcttgtgattggcagtggagggagggaacataccctggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
agttccggaaagatctcaaatgctgctgtctccatcactgatcacactgtcctggctcag
ttctgcaaagatgaaaagattgagttcgtggttgttggaccagaggcccctctagctgca
ggggttgttgaggacctggcctgtgcaggcgtacgatgctttggccccactgcacaagca
gcccagttagagtccagtaaaaagtttgccaaagagtttatggaccgacatggaatccca
actgcgcagtggaaagcctttaccaagcctgaagatgcctgcagctttattatgagcgca
aacttccctgctttggttgtgaaggctagtggccttgcagctgggaaaggcgtgattgtt
gcaaagaacaaagaggaggcctgcaaagctgtacaggagatcatgcaagaaaagtctttt
ggagcggctggagaaacagtggttgtggaagagtttctggacggggaagaagtgtcttgt
ctatgtttcactgatgggaagacagtggccccaatgcccccagcacaggaccataagcga
ttgctggatggagaccagggccccaacacagggggaatgggagcctattgcccaacaccc
caggttcctacagattgtttactaaaaattaagaacactattcttcagagaacagtagat
ggcatgcggcaggagggtgcgccttacacaggaattctctacgctggtataatgctgact
aaagatggcccaaaagttttggagtttaattgccgttttggtgatccagaatgccaagta
atcctcccacttcttaaaagtgacctttatgaagtgattcagtccaccctagatggcctg
ctgagtacatctctgcctgtttggctagaaaaccactctgccgtaactgttgtcatggca
agtaaagggtaccctggagcctacgccaagggtgtagagataacagggtttcctgaggcc
caggctttagggctgcaggtatttcatgcaggcactgctcttaaagatggcaaagtggtg
accagtgggggcagagtcctcacagtaacagccgtcggggaaaatcttgtgtcagccctt
gaagaagccaagaaaggactcgctgctataaagtttgagggagcagtgtataggaaggat
attggcttccgtgctgtggccttcctccagcagccaaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggttaagaaaattcaacctttggcaaaagcc
acctccagaccaggttgcaatgttgaccttggaggctttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagattgcccagctgtgcaacaagcatgacaccattggtcaggatttggtcgccatgtgt
gtgaatgacatcctagcacaaggagcagagcccctcttcttccttgattacttttcctgt
gggaaacttgacctcagtacaactgaagctgttgttgctggaattgctggagcttgtaga
caagctgactgtgctctcctgggtggggagaccgcagagatgcccgacatgtaccctcct
ggcgagtatgacctggctgggtttgctgtgggtgctatggaaagggatcagaaactccct
cggctcgaaaggatcaccgaaggggatgttgtcgttggagtagcttcatctggtcttcac
agcaatgggtttagccttgtgaggaagatcgtagcgaggtcttccctccaatattcttct
ccagcgcctggtggacatggtgaccagacgttaggggacttacttctaactccaaccagg
atctacagccattcactgttgcctatcatacgttcaggacgtgtcaaagccttggctcac
attactggaggtggactgctggagaacatccccagagtcctccccaagaagcttggggta
gatttagatgcctgcacctggaggatccccaaggtcttctcatggttacagcaggaagga
cagctctctgaagaagaaatggccagaaccttcaactgtggggttggagctgccctggtg
gtgtctaaggaccagacagaccaaatcctgcatgacattcggcagcgccaggaggaagcc
tgggtgataggcagtgtcgtggcctgtcctgaagattcccctcgtgtcagagtcaagaat
ctgatggaggccatgcaaatgaatggggcggtggtgtcaaatggcttcctgagaagtcat
ttccctgcccagcaaaagaagtcgagagtggctgtcttaatatccgggacaggatcgaac
ctccaagctctcatagacagcactaaagatgcaaagagctccacacacatcgtggttgtc
atctccaacaaagctggggtcgctggcctagacaaagcagaaaaagctggcattcccacc
agagtaattaatcataaattatataaaagtcgtgttgaatttgacaatgctgttgaccag
gtcctggaagagttctctgtagacatagtctgtcttgcaggattcatgagaattctctct
ggcccttttgtcagaaaatgggacgggaaaatgctcaacatccacccgtccttgctccct
tcttttaagggatcaaatgctcatgagcaagtcctggaagctggagtcacgattacgggc
tgtaccgtacactttgtagctgaagacgtagatgcaggacaaatcatcctgcaagaagct
gtccctgtgaagagggacgacagtgttgcaactctgtctgaaagagtcaaagccgcagag
catagagtcttccctgcagccctgcagctggtggccagcggggccgtgcggcttggaaaa
gacggcagcgtccactgggccagagagcagtga
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