Cricetulus griseus (Chinese hamster): 100750680
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Entry
100750680 CDS
T02813
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X3
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge04140
Autophagy - animal
cge04141
Protein processing in endoplasmic reticulum
cge04210
Apoptosis
cge04932
Non-alcoholic fatty liver disease
cge05010
Alzheimer disease
cge05012
Parkinson disease
cge05014
Amyotrophic lateral sclerosis
cge05016
Huntington disease
cge05017
Spinocerebellar ataxia
cge05022
Pathways of neurodegeneration - multiple diseases
cge05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100750680 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100750680 (Ern1)
09143 Cell growth and death
04210 Apoptosis
100750680 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100750680 (Ern1)
05012 Parkinson disease
100750680 (Ern1)
05014 Amyotrophic lateral sclerosis
100750680 (Ern1)
05016 Huntington disease
100750680 (Ern1)
05017 Spinocerebellar ataxia
100750680 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
100750680 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100750680 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100750680 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cge01001
]
100750680 (Ern1)
Enzymes [BR:
cge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100750680 (Ern1)
Protein kinases [BR:
cge01001
]
Serine/threonine kinases: Other
IRE family
100750680 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
100750680
NCBI-ProteinID:
XP_027283612
UniProt:
A0A8C2LDU9
LinkDB
All DBs
Position
7:complement(119343761..119441042)
Genome browser
AA seq
977 aa
AA seq
DB search
MPARWLLLLLALLLPPPSPGSFGSASTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSDSGDVLWIQNYASPVVAFYVWQREGLR
KVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIEDKGECVITPSTDLKFDPGLKGKSKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEKVINMVDQTSENTPSTV
SQAVEEKLVHAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQ
FQKELEKIQLLQQQQLPFHPHGDLTQDPEFLDSSGLFSESSGTSSSSPSPRASNHSLHSS
SSASKTGTNPSLEQDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGKIKAMISDFGLCKKLAV
GRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQ
RQANILLGACSLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPMEVQETLGSIPDDFVRYFTSRFPYLLSHTYRAMELCRHERLFQTY
YLHEPTEPQPPVTPDAL
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggtggctgttgctcctgctggcgctgctgctaccgccgcccagccccggg
agttttggaagtgccagcacagtaacactgcctgaaaccctgttgtttgtttcaaccctg
gatggaagtttgcatgctgtcagcaagaggacaggctcgatcaaatggactttaaaagaa
gatccagtcctgcaggttccaacacacgtggaagagcctgctttcctcccagatcccaat
gatggcagtctgtacacacttggaggcaaaaacaacgaaggcctgacgaaacttcccttt
accatcccagaattagtccaagcatctccatgccgaagttcagatggaatcctctacatg
ggtaaaaagcaggacatctggtatgttatcgacctcctgactggagagaagcagcagact
ttgtcatcggcctttgcagatagtctctgcccatcaacttccctgctgtatcttggacgg
acagaatataccatcactatgtatgacaccaagacccgagaacttcgttggaacgccacc
tattttgactatgcagcctcactgcccgaggatgatgtggactacaagatgtcccacttt
gtgtccaatggcgatggactagtggtaactgtggacagtgattctggggatgtcttgtgg
atccaaaactatgcctctcctgtggtagccttctatgtctggcagcgggagggcctgaga
aaggtgatgcacatcaacgtcgctgtggagactctccgctacctgaccttcatgtctggg
gaagtggggcgcatcaccaagtggaagtatccgttccccaaggagacagaggccaagagc
aagctgacgcctaccctgtacgttgggaagtactcaaccagcctctatgcctctccatca
atggtgcacgagggggttgctgtagtgccccgaggaagcactcttcctttgctggaaggt
ccccagacagatggtgtcaccattgaagacaaaggagagtgtgtgatcacccccagcaca
gacctcaagtttgaccctggactcaaagggaagagcaagctgaactacttgaggaattac
tggcttctcataggacaccatgaaactcctctgtctgcatctaccaagatgctggagaga
ttccccaacaacctgcccaaacatcgggaaaatgtgattcctgctgattcggaaaaaagg
agctttgagaaagttatcaacatggttgaccagacttcagaaaacacaccatccactgtg
tctcaggccgtggaagagaagctggtccatgcccccgccaagcctgaggcccccgttgac
tccatgctcaaggacatggctactattatcctgagcaccttcctgctggttggatgggtg
gccttcatcatcacttaccccctgagcatgcatcagcagcgccagctccagcaccagcag
ttccagaaggaactggagaaaattcagctcctgcagcagcagcagctgcccttccaccca
catggagaccttactcaggaccccgagtttctggattcatctggtctcttctcagagagc
tcaggcaccagcagctccagcccatcccccagagcctccaaccactcactccactccagc
agctctgcctccaagactggcaccaacccttccctggagcaggatgatgaggatgaggaa
actagaatggtgattgttgggaaaatttcattctgccccaaggatgtcctgggccatgga
gctgagggcacaattgtatacaaaggcatgtttgacaaccgtgatgtggcagtgaagagg
atcctccctgagtgttttagctttgcagaccgtgaggtccagctgcttcgagaatcagac
gagcatccaaacgtgatccgctacttttgcacagagaaggaccggcagttccaatacatt
gctattgaattgtgtgcagccactctgcaagagtatgtggagcagaaggactttgcccac
cttggcctggagcccatcaccttgcttcagcagaccacctcaggcctggcacacctgcac
tctctcaacatagttcacagagacctgaaaccccacaacattctcctctccatgcccaac
gcacatggcaagatcaaggccatgatctctgactttggcctctgcaagaagctggcagtg
ggtaggcacagtttcagccgtcgttcaggggtacctggcactgaaggctggatcgcccca
gagatgttgagtgaagactgcaaggaaaaccctacctacacagtggacatcttctctgca
ggctgtgttttttactatgtcatctctgagggcaaccatccttttggcaagtccttgcag
cggcaggccaacatcctcctgggcgcctgcagccttgactgcttccactcagacaagcat
gaggacgtcattgctcgtgaattgatagagaagatgattgctatggatccccagcaacgg
ccctctgcaaagcatgtgctaaaacacccattcttctggagcctggaaaagcagctccag
ttctttcaggatgtgagtgaccgaatagaaaaggagtccttggatggcccgatagtaaga
cagttggagagaggcgggagagccgtggtgaagatggactggcgggagaacatcactgtc
cccttgcagacagatctgcgaaaatttagaacctacaaaggtggctctgtcagagatctc
cttcgagccatgagaaacaagaaacaccactaccgagagctccccatggaggttcaggag
acgctgggctccatccccgatgactttgtgcgctatttcacatcacgcttcccctacctc
ctctcacacacctaccgagccatggagctctgcagacatgagagactcttccagacctac
tacttgcacgagcccacagaaccccagcctccagtgactccagatgcgctctga
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