KEGG   Cricetulus griseus (Chinese hamster): 100751933
Entry
100751933         CDS       T02813                                 
Symbol
Met
Name
(RefSeq) hepatocyte growth factor receptor isoform X1
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge01521  EGFR tyrosine kinase inhibitor resistance
cge04010  MAPK signaling pathway
cge04014  Ras signaling pathway
cge04015  Rap1 signaling pathway
cge04020  Calcium signaling pathway
cge04151  PI3K-Akt signaling pathway
cge04360  Axon guidance
cge04510  Focal adhesion
cge04520  Adherens junction
cge05100  Bacterial invasion of epithelial cells
cge05144  Malaria
cge05200  Pathways in cancer
cge05202  Transcriptional misregulation in cancer
cge05205  Proteoglycans in cancer
cge05206  MicroRNAs in cancer
cge05208  Chemical carcinogenesis - reactive oxygen species
cge05211  Renal cell carcinoma
cge05218  Melanoma
cge05223  Non-small cell lung cancer
cge05225  Hepatocellular carcinoma
cge05226  Gastric cancer
cge05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100751933 (Met)
   04014 Ras signaling pathway
    100751933 (Met)
   04015 Rap1 signaling pathway
    100751933 (Met)
   04020 Calcium signaling pathway
    100751933 (Met)
   04151 PI3K-Akt signaling pathway
    100751933 (Met)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100751933 (Met)
   04520 Adherens junction
    100751933 (Met)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    100751933 (Met)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100751933 (Met)
   05202 Transcriptional misregulation in cancer
    100751933 (Met)
   05206 MicroRNAs in cancer
    100751933 (Met)
   05205 Proteoglycans in cancer
    100751933 (Met)
   05208 Chemical carcinogenesis - reactive oxygen species
    100751933 (Met)
   05230 Central carbon metabolism in cancer
    100751933 (Met)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100751933 (Met)
   05226 Gastric cancer
    100751933 (Met)
   05218 Melanoma
    100751933 (Met)
   05211 Renal cell carcinoma
    100751933 (Met)
   05223 Non-small cell lung cancer
    100751933 (Met)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100751933 (Met)
  09174 Infectious disease: parasitic
   05144 Malaria
    100751933 (Met)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100751933 (Met)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cge01001]
    100751933 (Met)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100751933 (Met)
Protein kinases [BR:cge01001]
 Receptor tyrosine kinases (RTK)
  MET family
   100751933 (Met)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr TIG Pkinase Sema PSI Kinase-like Pkinase_fungal Linker_histone
Other DBs
NCBI-GeneID: 100751933
NCBI-ProteinID: XP_027245742
UniProt: A0A9J7F1W8
LinkDB
Position
1
AA seq 1389 aa
MKAPTVLSPGILVLLLTLLHRSHGECKEALVKSEMNMNMKYQLPNFTSETPIQNVVLHGH
HIYLGATNYIYVLSDKDLQKVSEYKTGPVLEHPDCFPCQDCSSKANSSGGVWKDNINMAL
LVDTYYDDQLISCGSVNRGTCQRHVLPPDNTADIQSEVHCMFSPHVDEESGQCPDCVVSA
LGAKVLLSEKDRFINFFVGNTINSTYFPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYIHAFESNHFIYFLTVQKETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGANLAKQIGASPNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVLSRTVPFTPHVNF
LLDSHPVSPEVIVEHPSDQNGYTLVVTGKKISKIPLNGLGCGHFQSCSQCLSAPSFVQCG
WCHNRCVRSDECSSGTWTQEICLPAIYKVFPTSAPLEGGTMLTICGWDFGFKKNNKFDLR
KTKVLLGNESCTLTLSESTTNTLKCTVGPSMSEHFNVSVIISNSRGTTQYSTFSYVDPVI
TSISPSYGPKAGGTLLTLTGKYLNSGSSRHISIGGKTCTLKSVSDSILECYTPAQTISAE
FPVKLKIDLANRETSGFSYWEDPIVYEIHPTKSFVSGGSTITGIGKNLNSVSIPKLVIDV
HEVGMNYTVACQHRSNSEIICCTTPSLQQLGLQLPLKTKAFFLLDGVLSKHFDLTYVHNP
VFKPFEKPVVISMGNENVLEIKGNDIDPEAVQGEVLKVGNKSCENVHWHSEAVLCTVPND
LLKLNSELNIEWKQAVSSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLRKRK
HIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
ACRPVQYPLTDLSPILNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNISTLNLLGITDIGEVSQFLTEGIIMK
DFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGM
KYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMAL
ESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLLQPEYCPDAL
YEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGEHYVHVNTTYVNVKCVAPYPSLLSSQ
DNIDGEVNT
NT seq 4170 nt   +upstreamnt  +downstreamnt
atgaaggctcccaccgtgctgtcacctggcattctggtgctgctgctgaccttgctgcat
aggagccatggggagtgcaaggaggccctagtgaagtccgagatgaacatgaatatgaag
taccagcttcccaactttacctcagaaaccccaatccagaatgtcgttctacacgggcat
catatttacctcggagccacaaactacatttacgttttaagtgacaaagaccttcagaag
gtgtccgagtacaagactgggcccgtgttggagcacccagattgttttccgtgtcaggac
tgcagcagcaaagccaattcatcaggaggtgtctggaaagacaatatcaacatggctctg
cttgttgacacatactatgacgatcaactcattagctgtggcagtgtcaacagagggacc
tgccagcggcatgtccttcctcccgacaatactgctgacatacagtccgaggttcactgc
atgttctccccacatgtggatgaagaatcaggccagtgtcctgactgcgtagtgagtgcc
ctgggagccaaagtcctcctgtctgaaaaggaccggtttatcaatttcttcgtggggaat
acaataaattctacctactttcctgatcattcattgcattcgatatcggtgagacgcctg
aaggaaacacaagatggctttaagtttttgacagaccagtcctatattgatgtcttacct
gaattccgagattcttaccccataaagtacatacatgcctttgaaagcaaccattttatt
tactttttgactgtccaaaaggaaaccctagatgctcagacttttcatacaagaataatc
aggttctgttctgtagactctgggttgcactcctacatggaaatgcctctggagtgtatt
ctcacagaaaaaagaaggaagagatccacaagggaagaggtgtttaatatcctccaagct
gcttatgtcagtaaaccaggagccaatctcgctaagcaaataggagccagcccaaatgat
gacatactctacggtgtgttcgcacaaagcaagccagactctgctgaacccatgaatcga
tcggcagtctgtgcattccctatcaaatatgtcaatgaattcttcaacaagatagtcaac
aaaaacaacgtgagatgtctccagcatttttatggacccaaccatgagcactgtttcaat
aggaccctgctgaggaattcatcaggctgtgaagtacgcagtgatgaatatcggacagag
tttaccacggctttacagcgcgttgatttattcatgggccagttcaaccaagtgctcttg
acatctatatccaccttcatcaaaggtgacctcaccattgctaatctagggacatcagaa
ggtcgattcatgcaggttgtgctttctcggaccgtacctttcacccctcatgtgaacttc
ctcctggattcccatcctgtatctccagaagttattgtggaacatccatcagaccaaaat
ggctacacattggttgtcacagggaagaagatctccaagatcccattgaatggcctgggc
tgtggacatttccagtcttgcagtcagtgtctctctgccccttcctttgtgcagtgtggc
tggtgccacaatcgatgtgtgcgttctgatgaatgctccagcggcacatggactcaagag
atctgcctgcctgccatttataaggttttccccactagtgcaccccttgaaggaggaaca
atgctgaccatatgcggctgggactttggattcaagaagaataataaatttgatttaagg
aaaaccaaagtactgcttggcaatgagagctgtaccttgaccttaagtgaaagcacaaca
aatacgttgaaatgcacagttggtccttcgatgagtgagcacttcaatgtgtctgtaatc
atctcaaacagtcgagggacaacacaatacagtacattttcctatgtggatcctgtaata
acaagtatttctccaagttatggtcctaaggctggaggcactttgctcactctaactgga
aagtatctaaacagtgggagttctagacacatttcaattggtgggaaaacgtgtacttta
aaaagtgtatcagatagtattcttgaatgttataccccagcccaaaccatctctgctgag
tttcccgtgaaactgaaaattgatttagctaaccgagagacaagtggcttcagttactgg
gaggatcctattgtctatgaaatccacccgaccaaatcttttgttagtggtggaagcaca
ataacgggtattggaaaaaacctgaattcggtcagcatcccaaagctggtaattgatgtg
catgaagtggggatgaactacacagtggcatgtcagcatcgctccaattcagagatcatc
tgctgcaccactccttcattgcaacagctgggtctgcaactccccctgaagaccaaagcc
tttttcctgttagacggggttctttccaaacactttgatctcacttatgtgcataatcct
gtgtttaagccttttgaaaagcccgtggtgatctcaatgggcaatgaaaatgtactagaa
attaagggaaatgatattgaccctgaagcagttcaaggtgaagtgttaaaagttggaaat
aagagctgtgagaatgtacactggcactctgaagctgttttatgtacagtccccaatgac
ctgctgaaactgaacagcgagctaaatatagagtggaagcaagcagtctcttcaactgtc
cttggaaaagtgatcgttcaaccagatcagaatttcacaggattgatcgttggtgtggtc
tcaatatcaataatacttttattattactcgggctcttcctgtggctgagaaaaaggaag
catattaaagatctgggcagtgaattagttcgctatgacgcaagagtacacactcctcat
ttggatagacttgtcagtgcccgaagtgtaagtccaactacagagatggtttcaaatgag
tctgtagactacagagctacttttccagaagaccagtttcccaactcctctcagaatgga
gcatgcaggccagtgcagtaccctctgacggatctgtcccccattctcaatagtggagac
tcggacatatccagcccattactacaaaacactgttcacattgacctcagcgctctaaat
ccagagctggtccaagcagttcagcacgtagtgattgggcccagtagcctgattgtgcat
ttcaatgaagtcataggaagagggcattttggctgtgtttatcatgggaccttgttggac
aatgatggcaagaaaatccactgtgctgtgaaatccttgaatatctcaacactgaatctc
ctaggaatcacggatataggagaagtctcccagtttctgactgagggcatcatcatgaag
gatttcagtcatcccaatgttctctcgctcttggggatctgccttcggagcgaagggtcc
ccattagtggttctaccatatatgaaacacggagatcttcggaatttcatacggaatgag
actcataacccaactgtcaaagatcttataggatttggtcttcaagtagccaaaggcatg
aaatatcttgccagcaaaaagtttgttcacagagacttagctgcaaggaactgcatgttg
gatgaaaaattcactgtcaaggttgctgattttggtcttgccagagacgtgtatgataaa
gaatactatagtgtgcacaacaaaaccggtgccaaactgcccgtgaagtggatggctttg
gagagtctgcaaacacagaagtttaccaccaaatcagatgtgtggtcctttggtgttctt
ctctgggagctcatgacaagaggagcgcctccgtatcctgatgtgaacacatttgatatc
accatctacttattacaaggcagaagactcttgcaaccagaatactgcccagacgccttg
tatgaagtgatgctaaaatgctggcaccccaaagctgaaatgcgcccatccttttctgaa
ctggtgtccaggatatcgtcaatcttctccactttcattggggagcactacgtccatgtg
aacactacttacgtgaatgtaaaatgtgttgctccatatccttccctgttgtcatcccaa
gacaacattgatggtgaagtgaacacatga

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