Cricetulus griseus (Chinese hamster): 100752475
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Entry
100752475 CDS
T02813
Symbol
Plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00562
Inositol phosphate metabolism
cge01100
Metabolic pathways
cge01521
EGFR tyrosine kinase inhibitor resistance
cge04012
ErbB signaling pathway
cge04014
Ras signaling pathway
cge04020
Calcium signaling pathway
cge04062
Chemokine signaling pathway
cge04064
NF-kappa B signaling pathway
cge04066
HIF-1 signaling pathway
cge04070
Phosphatidylinositol signaling system
cge04072
Phospholipase D signaling pathway
cge04360
Axon guidance
cge04370
VEGF signaling pathway
cge04380
Osteoclast differentiation
cge04517
IgSF CAM signaling
cge04611
Platelet activation
cge04613
Neutrophil extracellular trap formation
cge04625
C-type lectin receptor signaling pathway
cge04650
Natural killer cell mediated cytotoxicity
cge04662
B cell receptor signaling pathway
cge04664
Fc epsilon RI signaling pathway
cge04666
Fc gamma R-mediated phagosome formation
cge04670
Leukocyte transendothelial migration
cge04722
Neurotrophin signaling pathway
cge04750
Inflammatory mediator regulation of TRP channels
cge04919
Thyroid hormone signaling pathway
cge04933
AGE-RAGE signaling pathway in diabetic complications
cge04935
Growth hormone synthesis, secretion and action
cge05167
Kaposi sarcoma-associated herpesvirus infection
cge05169
Epstein-Barr virus infection
cge05170
Human immunodeficiency virus 1 infection
cge05171
Coronavirus disease
cge05200
Pathways in cancer
cge05205
Proteoglycans in cancer
cge05206
MicroRNAs in cancer
cge05214
Glioma
cge05223
Non-small cell lung cancer
cge05225
Hepatocellular carcinoma
Module
cge_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100752475 (Plcg2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100752475 (Plcg2)
04014 Ras signaling pathway
100752475 (Plcg2)
04370 VEGF signaling pathway
100752475 (Plcg2)
04064 NF-kappa B signaling pathway
100752475 (Plcg2)
04066 HIF-1 signaling pathway
100752475 (Plcg2)
04020 Calcium signaling pathway
100752475 (Plcg2)
04070 Phosphatidylinositol signaling system
100752475 (Plcg2)
04072 Phospholipase D signaling pathway
100752475 (Plcg2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
100752475 (Plcg2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100752475 (Plcg2)
04613 Neutrophil extracellular trap formation
100752475 (Plcg2)
04625 C-type lectin receptor signaling pathway
100752475 (Plcg2)
04650 Natural killer cell mediated cytotoxicity
100752475 (Plcg2)
04662 B cell receptor signaling pathway
100752475 (Plcg2)
04664 Fc epsilon RI signaling pathway
100752475 (Plcg2)
04666 Fc gamma R-mediated phagosome formation
100752475 (Plcg2)
04670 Leukocyte transendothelial migration
100752475 (Plcg2)
04062 Chemokine signaling pathway
100752475 (Plcg2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
100752475 (Plcg2)
04919 Thyroid hormone signaling pathway
100752475 (Plcg2)
09156 Nervous system
04722 Neurotrophin signaling pathway
100752475 (Plcg2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100752475 (Plcg2)
09158 Development and regeneration
04360 Axon guidance
100752475 (Plcg2)
04380 Osteoclast differentiation
100752475 (Plcg2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100752475 (Plcg2)
05206 MicroRNAs in cancer
100752475 (Plcg2)
05205 Proteoglycans in cancer
100752475 (Plcg2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100752475 (Plcg2)
05214 Glioma
100752475 (Plcg2)
05223 Non-small cell lung cancer
100752475 (Plcg2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100752475 (Plcg2)
05171 Coronavirus disease
100752475 (Plcg2)
05167 Kaposi sarcoma-associated herpesvirus infection
100752475 (Plcg2)
05169 Epstein-Barr virus infection
100752475 (Plcg2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100752475 (Plcg2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100752475 (Plcg2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cge04131
]
100752475 (Plcg2)
Enzymes [BR:
cge01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
100752475 (Plcg2)
Membrane trafficking [BR:
cge04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
100752475 (Plcg2)
Endocytosis
Macropinocytosis
Phospholipase C
100752475 (Plcg2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF_HAND_2_PLCG
C2
SH3_1
SH3_9
PH
EF_HAND_1_PLCG
PH_12
SH2_1
SH3_2
PH_14
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
100752475
NCBI-ProteinID:
XP_027266579
UniProt:
A0A8C2MLP8
LinkDB
All DBs
Position
3
Genome browser
AA seq
1267 aa
AA seq
DB search
MTTMVNVDTLPEYEKSQIKRALELGMVMTVFSARKGTSERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKATVSRHKADCCFTIFYGTQFVLSTLSLATDSKED
AMKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVS
SVKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDA
SAIHLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLYVDEFLTYLFSRE
NSIWDEKYDTVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIEL
DCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMA
KVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKTQ
GELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQAVEEELVQDTTPTELHFGEKWFHKKVE
RRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMK
YYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAED
MLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVS
YYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALY
DYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQ
IIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFE
WFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSF
VETKADSIVRQKPIDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTAD
KYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGR
SIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYE
EDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLECEEELYS
SCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRV
SNSRFYS
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
atgactaccatggtcaatgtggacacccttccggaatatgagaagagtcagatcaagaga
gccctggagctagggatggtgatgactgtgttcagtgcccggaagggcacctcagagcgg
aggacggtgcaggtgatcatggagactcggcaggtggcatggagcaagactgcggacaag
atcgagggcttcttggacatcatggaaataaaggaaattcgtccagggaagaactccaag
gactttgagcgagccaaggccacagtctcccgccacaaggcagactgctgcttcaccatc
ttttacggcacccagttcgtcctcagcactctcagtttggcaactgactcaaaggaggat
gcaatgaagtggctctctggcttgaagatcctacaccaggaagcaatgagtgcatctact
cccaccatgattgagagttggctgagaaagcagatttattcagtagatcaaaccagaaga
aacagcatcagtctccgggagctgaaggccatcttgcccctggtcaacttcaaagtgagc
agtgtcaagttcctcaaggacaagctggtggaaattggtgcacagaaagatgagctcagt
tttgaacagttccatctcttctataaaaaactcatgtttgaccagcaaaaatcgatactt
gatgaattcaaaaaggactcctccgtgttcattctagggaacacagaccggcctgacgcc
tctgctatccacctacaggacttccagaggtttcttttacatgaacaacaggagctatgg
gctcaggatctgaacaaagtccgggaacggatgaccaagtttatcgatgacaccatgaga
gaaactgcagagcccttcttgtatgtggatgagttcctcacatacctgttttcacgggag
aacagcatctgggatgagaagtatgacacggtggacatgcaggacatgaacaaccccttg
tcacattactggatctcctcttcccacaacacgtacctcactggggaccagctgcgtagt
gagtcctccacggaagcatatatccgctgtctgcgggctggctgtcgttgcatagagttg
gactgctgggatggacctgatggcaaacctatcatctaccacggctggacacggaccacc
aagatcaagtttgatgacgttgttcaggccatccgagaccatgcctttgtcacctccagc
ttccccgtgatcttgtccattgaggagcactgcagcgtggagcagcagcgtcacatggcc
aaggtgttcaaggaagtgttaggagacctgctgttgacgaagcccacggaggccagtgct
gaccagttgccctcacccagccagcttagagagaagatcattatcaagcataagaagctg
ggcccccgaggtgacgtcgatgtcaacgtggaggacaagaaagatgagcacaagacccag
ggagagctatacatgtgggactccattgaccagaaatggactcgccactactgtgccatt
gctgatgccaagctgtccttcagtgatgacatcgaacaggctgtggaggaggaactggtc
caggacacaacccccacggagctgcattttggggagaaatggttccataagaaagtggag
aggaggaccagtgcagagaaactgctgcaagagtactgtgctgagacaggggccaaggac
ggcaccttcctggttcgggagagcgagaccttccccaatgactacacactctccttctgg
cggtctggtcgggtgcagcactgtcgaatccggtccaccatggagggtggagtcatgaag
tactacctgacagacaaccttacattcaacagcatctacgcccttatccagcactaccgt
gaggcacacctacgctgtgcagagttcgagctgcggctcaccgacccagtgcccaacccc
aacccacatgagtccaagccgtggtactatgacaggctgagcaggggggaagcagaggac
atgttgatgcggattccccgagatggagccttcctcattcggaagcgcgaagggaccgac
tcctatgccatcaccttcagggccaggggcaaggtgaaacactgtcgcatcaaccgggat
ggtcggcactttgtgctggggacctctgcctactttgagagcctggtggagcttgtcagc
tactatgagaagcacgcgctctatcgcaagatgaggctgcgctatcctgtgacccccgag
ctcctggagcgatataatatggaaagagacatcaactctctctatgacgtcagcaggatg
tatgtggatccaagtgaaatcaacccttctatgcctcagaggactgtgaaagcactctat
gactacaaagccaagcgcagcgatgagttgaccttctgccgtggcgcccttatccacaac
gtctccaaggagccagggggatggtggaaaggggactacgggacccggatccagcagtac
ttcccgtccaactatgttgaggatatctcagcaggtgatgctgaggagatggagaagcag
attattgaagacaatccccttgggtctctctgcagaggcatattggaccttaatacctat
aatgttgtgaaggccccccaggggaaaaaccagaaagcattcgtcttcatcctggagcct
aagaagcagggggaccctcctgtggagtttgcgaccgaccgtgtggaggagctgtttgag
tggtttcagagcatccgggagatcacttggaagattgacaccaaggagaacaacatgaag
tactgggagaggaaccagtccatcgccatcgagctttctgacttggttgtctactgcaag
ccaaccagcaaaaccaaggaccatttggaaaaccctgacttccgagaaatccgctccttt
gtggagacgaaggcggacagcattgtgcggcagaagcccattgatctattgcggtacaat
cagaagggcctcacacgtgtctaccctaagggacagagagttgactcttcaaactatgac
cccttccgcctgtggctgtgtggctcccagatggtggcgctcaatttccagactgcagac
aagtacatgcagatgaaccatgcactgttttcactcaatgggcggacaggctatgtccta
cagcctgagagcatgcggtctgagaagtatgacccgatgccaccagagtcccagaggaag
atcctgatgacactcactgtcaaggttcttggggcacgccacctccccaaactagggcgg
agtattgcctgtccctttgtagaggtggaaatctgtggggctgagtacgacagcaacaag
ttcaagacaacggttgtgaatgacaatggcctcagccctgtctgggctccaacgcaggag
aaggtgacatttgaaatttatgatccaaaccttgcattccttcgctttgtggtctatgag
gaggacatgttcagtgaccccaacttcctggctcatgccacataccccattaaagggatc
aagtcagggtttagatcagtccctctgaagaatggatacagtgaagacatcgagttggct
tccctcctggttttctgtgagatgcggccggtcctggagtgtgaagaggaactctactcc
tcctgtcgccaactgaggagacggcaagaagaactcaataatcagctcttcctgtacgac
acacaccagaacctgcgtggagccaaccgcgatgccttggtgaaggagttcaatgtcaac
gagaaccagctgcagctgtaccaggagaagtgtaaccggaggttgagagagaagagagtc
agcaacagcaggttctactcctag
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integrated database retrieval system
