KEGG   Cricetulus griseus (Chinese hamster): 100752606
Entry
100752606         CDS       T02813                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge00140  Steroid hormone biosynthesis
cge01100  Metabolic pathways
cge04913  Ovarian steroidogenesis
cge04925  Aldosterone synthesis and secretion
cge04927  Cortisol synthesis and secretion
cge04934  Cushing syndrome
Module
cge_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:cge00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100752606
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100752606
   04925 Aldosterone synthesis and secretion
    100752606
   04927 Cortisol synthesis and secretion
    100752606
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100752606
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:cge00199]
    100752606
Enzymes [BR:cge01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     100752606
Cytochrome P450 [BR:cge00199]
 Cytochrome P450, animal type
  CYP11 family
   100752606
SSDB
Motif
Pfam: p450 Cytomega_US3
Other DBs
NCBI-GeneID: 100752606
NCBI-ProteinID: XP_035300291
UniProt: A0A9J7H0T8
LinkDB
Position
4:169594164..169625340
AA seq 428 aa
MESVYILDPEDAALLFSCEGPYPERYLVPPWVAYHQYYKRPIGVLFKSSDAWKRDRLVLN
QEVMAPEAIKNFVPLLETVVRDFIDVLHRRIKQQKSGNFSGDISGDLFRFAFESITSVVF
GERLGMLEEIVDPESQRFIDAVYQMFHTSVPMLNLPPELFRFFRTKTWKEHAAAWDVIFE
KAHDYTKNFYWDLRQKQEYSKYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQ
WNLYEMAHNLEVQEMLRAEVLAARRQAQGDMVKMVQLVPLLKASIKETLRLHPISVTLQR
YLADDLVLRNYRIPAKMLVQVANYAMGRVPSFFPNPNKFDPTRWLEKSKNITHFRYLGFG
WGIRQCLGRRIAELEMTIFLINVLENFRIEVQSFHDVGTKFNLILMPEKPIFFNFHPLKK
DLGTTMIR
NT seq 1287 nt   +upstreamnt  +downstreamnt
atggagtctgtttatattctggaccctgaagatgcagcgctgctcttttcatgcgagggt
ccctacccggaacgataccttgtgcccccttgggttgcttatcaccagtattacaagaga
cccataggggtcctgtttaagagttcagacgcttggaagagagacagacttgtcttaaac
caggaagtgatggcgcctgaagccatcaagaacttcgtgcccctgctggaaactgtagtt
cgggacttcatcgatgtcttacacagacgcatcaagcagcagaagtctggaaatttctca
ggggacatcagtggtgacttgttccgctttgcctttgagtccatcaccagtgttgtattt
ggggagcgcctgggaatgttggaggagatagtggaccctgagtcccagcggttcatcgat
gccgtctaccagatgtttcacaccagtgtccccatgctcaacctgcctccagaacttttt
cgattcttcagaactaagacctggaaggagcatgcagctgcctgggatgtgatttttgaa
aaagctcatgattacaccaagaacttctactgggacttaaggcagaagcaagagtacagc
aagtaccctggtgtcctttatagcctcctgggtggcaacaagctgcccttcaagaacatc
caggccaacattacagagatgctggcaggaggggtggacacgacctccatgaccctgcag
tggaacctttatgagatggcacacaacttggaggtacaggagatgctgcgggcagaggtt
ctggctgcccggcgccaggcccagggagacatggtcaagatggtgcagttggtcccactc
ctaaaagccagtatcaaggagacactgagactccaccccatctccgtgaccttgcagaga
tatcttgcagatgacctggtacttcgaaattacaggattcctgccaagatgctggtgcag
gtggctaactatgccatgggccgagtacccagcttcttccccaacccaaacaagtttgac
ccaactcggtggctggaaaaaagcaaaaatatcacccacttccgttacttgggctttggc
tggggtattcggcagtgtctgggccggcggattgcagagctggagatgaccatcttcctc
attaatgtgctggagaactttagaattgaagtccagagtttccatgatgtggggaccaag
ttcaacctcatcctgatgcctgagaagcccatcttcttcaacttccatcctctcaagaag
gaccttggcacaaccatgatcagatag

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