Cricetulus griseus (Chinese hamster): 100755939
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Entry
100755939 CDS
T02813
Symbol
Pde8b
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00230
Purine metabolism
cge01100
Metabolic pathways
cge04927
Cortisol synthesis and secretion
cge04934
Cushing syndrome
cge05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100755939 (Pde8b)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
100755939 (Pde8b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100755939 (Pde8b)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100755939 (Pde8b)
Enzymes [BR:
cge01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
100755939 (Pde8b)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
JetB
DHH
Motif
Other DBs
NCBI-GeneID:
100755939
NCBI-ProteinID:
XP_027257508
UniProt:
A0A8C2QIK0
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All DBs
Position
2
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AA seq
885 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTSSLSQGPTAPLHGLFVQTDAADAMPPSRAAG
PSGAVRVRRSRAELGSGSSTGSSGPAVTTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHRIHRDSGDNSQTEPPSFRHKSRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITI
NDVPTSIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPLAAESEGSDCECNPTGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSES
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccatgtctcacagagcggcgtgatctactgccgggactca
gatgagtccaactcgccccgccagaccagcagcctgtcgcagggccccacggcgcccctg
cacggcctcttcgtgcagaccgacgccgccgacgccatgcccccgagccgcgcggcggga
ccctcgggcgctgtccgagtccgtaggtcccgggctgagctgggcagtggcagtagcacg
gggtcctcagggccagcagtgaccacctgccggggccggaggcgtcactgctgcagcagt
gctgaggccgagacccagaccagctacaccagtgtcaagcaggtgtcttctgcggaggtg
cgcattgggcccatgagactgacgcaggaccctatccaggttttgctaatctttgcaaag
gaggacagccagagtgatggcttctggtgggcctgtgacagggctggctacagatgcaac
atcgctcgtactccagagtcggcccttgagtgtttcctggacaagcatcatgaaattatt
gtgattgatcacaggcaaacccggaacttcgatgcagaagcggtgtgcaggtcaatccgg
gccactaacccctctgagcacaccgtgatcctggctgtggtttcacaagcatccgatgac
catgaagaggcctcagttcttcctcttctccacgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaaattacgggcctgtaattcagtgtttacagcgttagaccactgtcatgaa
gccatagaaataacaagtgatgatcatgtgattcagtatgtcaaccccgcctttgagagg
atgatgggctaccacaaaggggagcttctggggaaagaactcgctgacctacctaagagt
gacaagaaccgggcagacctcctggacaccatcaatacgtgcatcaagaagggaaaggag
tggcagggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaag
atcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaagctg
tgctgtaccactgacaataacaagcagattcacaggattcatcgtgattcaggggataac
tctcaaacagaacctccttcattcagacacaagagcaggaggaaagagtccattgatgtg
aaatcaatatcttctcgaggcagcgatgctccaagcctacagaatcgccgctacccctcc
atggcaaggatccactccatgaccatagaggcccccatcacaaaggttataaatataatc
aatgcagctcaagagaacagcccagttacagtagcagaagccttggacagagttctagaa
attttacggaccacagaactgtactcccctcagctgggaaccaaagatgaagatcctcac
accagtgatcttgttggaggcctgatgactgatggcttgagaagactgtcggggaatgag
tatgtgttcacaaagaatgtgcaccagagtcatagtcaccttgccatgcccataaccatc
aatgatgtccccacaagtatcgcccagttactggataatgaggaaagctgggacttcaac
atctttgaattggaagcagttacacataaaaggccattggtgtacctgggcttaaaggtc
ttctctcggtttggagtatgtgaatttttaaactgcactgaaaccactcttcgggcctgg
ctgcaagtgattgaagccaactaccactcctccaatgcctaccacaattccacccacgct
gctgatgtcctacacgccacagctttcttccttggaaaggaaagagtgaagggaagcctc
gatcagctggacgaggtagctgctctgattgctgcaacagtccatgatgtggatcaccct
ggaagaaccaactccttcctgtgcaacgcgggcagtgagctggctgtgctctacaatgac
actgcagtcttggagagtcaccacacggccctggccttccagcttactgtcaaggacacc
aagtgcaacatcttcaagaacattgacaggaaccattaccgaacgctacgccaggctatt
attgacatggttttggctacagagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccactggcagctgagagtgagggcagcgactgtgaatgcaaccct
actggaaagaacttccctgaaaaccagatcctgatcaagcgcatgatgatcaagtgtgct
gacgtggccaacccatgccgacccttggacctgtgcattgagtgggctgggaggatctct
gaggagtactttgcacagacagatgaggagaagaggcaggggctacctgttgtgatgcca
gtgtttgaccgtaatacctgcagcatccccaagtcccagatctccttcattgactacttt
ataacggacatgtttgatgcttgggatgcctttgcgcacctgccagccctgatgcagcac
ttggcagataactacaaacactggaagacactggatgacctcaagtgcaaaagtctgaga
cttccatctgagagctaa
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