KEGG   Cricetulus griseus (Chinese hamster): 100757188
Entry
100757188         CDS       T02813                                 
Symbol
Src
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X2
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge01521  EGFR tyrosine kinase inhibitor resistance
cge01522  Endocrine resistance
cge04012  ErbB signaling pathway
cge04015  Rap1 signaling pathway
cge04062  Chemokine signaling pathway
cge04081  Hormone signaling
cge04137  Mitophagy - animal
cge04144  Endocytosis
cge04360  Axon guidance
cge04370  VEGF signaling pathway
cge04510  Focal adhesion
cge04517  IgSF CAM signaling
cge04518  Integrin signaling
cge04520  Adherens junction
cge04530  Tight junction
cge04540  Gap junction
cge04611  Platelet activation
cge04613  Neutrophil extracellular trap formation
cge04625  C-type lectin receptor signaling pathway
cge04727  GABAergic synapse
cge04750  Inflammatory mediator regulation of TRP channels
cge04810  Regulation of actin cytoskeleton
cge04912  GnRH signaling pathway
cge04915  Estrogen signaling pathway
cge04917  Prolactin signaling pathway
cge04919  Thyroid hormone signaling pathway
cge04921  Oxytocin signaling pathway
cge04926  Relaxin signaling pathway
cge05100  Bacterial invasion of epithelial cells
cge05135  Yersinia infection
cge05152  Tuberculosis
cge05161  Hepatitis B
cge05163  Human cytomegalovirus infection
cge05167  Kaposi sarcoma-associated herpesvirus infection
cge05168  Herpes simplex virus 1 infection
cge05203  Viral carcinogenesis
cge05205  Proteoglycans in cancer
cge05207  Chemical carcinogenesis - receptor activation
cge05208  Chemical carcinogenesis - reactive oxygen species
cge05219  Bladder cancer
cge05417  Lipid and atherosclerosis
cge05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100757188 (Src)
   04015 Rap1 signaling pathway
    100757188 (Src)
   04370 VEGF signaling pathway
    100757188 (Src)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100757188 (Src)
   04517 IgSF CAM signaling
    100757188 (Src)
   04518 Integrin signaling
    100757188 (Src)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100757188 (Src)
   04137 Mitophagy - animal
    100757188 (Src)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100757188 (Src)
   04520 Adherens junction
    100757188 (Src)
   04530 Tight junction
    100757188 (Src)
   04540 Gap junction
    100757188 (Src)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100757188 (Src)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100757188 (Src)
   04613 Neutrophil extracellular trap formation
    100757188 (Src)
   04625 C-type lectin receptor signaling pathway
    100757188 (Src)
   04062 Chemokine signaling pathway
    100757188 (Src)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100757188 (Src)
   04915 Estrogen signaling pathway
    100757188 (Src)
   04917 Prolactin signaling pathway
    100757188 (Src)
   04921 Oxytocin signaling pathway
    100757188 (Src)
   04926 Relaxin signaling pathway
    100757188 (Src)
   04919 Thyroid hormone signaling pathway
    100757188 (Src)
  09156 Nervous system
   04727 GABAergic synapse
    100757188 (Src)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100757188 (Src)
  09158 Development and regeneration
   04360 Axon guidance
    100757188 (Src)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100757188 (Src)
   05207 Chemical carcinogenesis - receptor activation
    100757188 (Src)
   05208 Chemical carcinogenesis - reactive oxygen species
    100757188 (Src)
   05203 Viral carcinogenesis
    100757188 (Src)
  09162 Cancer: specific types
   05219 Bladder cancer
    100757188 (Src)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100757188 (Src)
   05168 Herpes simplex virus 1 infection
    100757188 (Src)
   05163 Human cytomegalovirus infection
    100757188 (Src)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100757188 (Src)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100757188 (Src)
   05152 Tuberculosis
    100757188 (Src)
   05100 Bacterial invasion of epithelial cells
    100757188 (Src)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100757188 (Src)
   05418 Fluid shear stress and atherosclerosis
    100757188 (Src)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100757188 (Src)
   01522 Endocrine resistance
    100757188 (Src)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cge01001]
    100757188 (Src)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cge04131]
    100757188 (Src)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100757188 (Src)
Protein kinases [BR:cge01001]
 Non-receptor tyrosine kinases
  SRC family
   100757188 (Src)
Membrane trafficking [BR:cge04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100757188 (Src)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    100757188 (Src)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    100757188 (Src)
  Macropinocytosis
   Kinases
    100757188 (Src)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 SH3_10 Haspin_kinase DUF7063 SH3_3 DUF8712
Other DBs
NCBI-GeneID: 100757188
NCBI-ProteinID: XP_027277069
UniProt: G3GXX7
LinkDB
Position
6:complement(22070696..22120470)
AA seq 536 aa
MGSNKSKPKDASQRRRSLEPAENVHGAGGAFPASQTPSKPASADGHRGPSAAFVATTAAE
SKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1611 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaagatgccagccagaggcgccgcagcctggagccc
gccgagaacgtgcacggggccgggggagccttcccggcttcgcagacacctagcaagccc
gcctccgccgacggccaccgagggcccagcgccgccttcgtggccaccacggccgctgag
tccaagctcttcggaggcttcaactcttcggacacggtcacctccccgcagagggccggg
cctctggcaggtggggtgaccacctttgtggccctctatgactatgagtcaaggacagag
actgacctgtccttcaagaaaggagagcggctacagattgtcaacaacacagagggagac
tggtggctggcacactcgctgagcacgggacagaccggttacatccctagcaactatgtg
gcaccctccgactccatccaggctgaggagtggtactttggcaagatcactagacgggag
tcagagcggctactgctcaatgctgagaacccaagagggaccttccttgtgagggagagt
gagacaacgaaaggtgcctactgcctttctgtatccgacttcgacaatgccaagggcctc
aatgtgaaacactataagatccgaaaactggacagcggtggcttctacatcacctcccgc
acccagttcaacagcctgcagcagctagtggcttactactccaagcatgctgatggcctg
tgccaccgcctcactaccgtgtgccccacgtccaagcctcagacccagggcctggccaag
gatgcctgggagatcccccgggagtccttgcgtctggaggtcaagttgggccaaggctgc
ttcggagaggtgtggatggggacctggaatggcaccacgagggttgccatcaaaaccctg
aagccgggcaccatgtctccagaggccttcctgcaggaggcccaagtcatgaagaaactg
aggcatgagaaactggtgcagctgtatgcggtggtgtcggaggaacccatttacatcgtg
acagagtacatgagcaagggtagtctgctggactttctcaagggggaaaccggcaaatac
ctgcggctaccgcagctggtggacatggctgctcagatcgcctctggtatggcctatgtg
gaacggatgaactatgtgcacagggacctccgagctgccaatatcctggttggggagaat
ctggtgtgtaaggtggctgactttggtctggcccggctcatagaagacaacgaatacaca
gcccggcaaggtgccaaattccccatcaagtggactgctcccgaagctgctctgtacggc
aggttcactatcaagtcagatgtgtggtcctttgggatcctgctgaccgagctcaccacg
aagggacgggtgccctatcctgggatggtgaaccgtgaggtgctggaccaggtggagcgg
ggctaccggatgccttgccccccggagtgccctgagtccctgcatgacctcatgtgccag
tgctggcggaaggagcctgaggagcggcccaccttcgagtacctgcaggccttcctggag
gactacttcacatccaccgagccgcagtaccagcctggggagaacctatag

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