KEGG   Cricetulus griseus (Chinese hamster): 100757513
Entry
100757513         CDS       T02813                                 
Symbol
Rps6kb1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge01521  EGFR tyrosine kinase inhibitor resistance
cge01522  Endocrine resistance
cge04012  ErbB signaling pathway
cge04066  HIF-1 signaling pathway
cge04140  Autophagy - animal
cge04150  mTOR signaling pathway
cge04151  PI3K-Akt signaling pathway
cge04152  AMPK signaling pathway
cge04211  Longevity regulating pathway
cge04213  Longevity regulating pathway - multiple species
cge04350  TGF-beta signaling pathway
cge04371  Apelin signaling pathway
cge04666  Fc gamma R-mediated phagocytosis
cge04714  Thermogenesis
cge04910  Insulin signaling pathway
cge04931  Insulin resistance
cge05163  Human cytomegalovirus infection
cge05165  Human papillomavirus infection
cge05170  Human immunodeficiency virus 1 infection
cge05200  Pathways in cancer
cge05205  Proteoglycans in cancer
cge05207  Chemical carcinogenesis - receptor activation
cge05210  Colorectal cancer
cge05212  Pancreatic cancer
cge05221  Acute myeloid leukemia
cge05224  Breast cancer
cge05225  Hepatocellular carcinoma
cge05226  Gastric cancer
cge05231  Choline metabolism in cancer
cge05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:cge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100757513 (Rps6kb1)
   04350 TGF-beta signaling pathway
    100757513 (Rps6kb1)
   04371 Apelin signaling pathway
    100757513 (Rps6kb1)
   04066 HIF-1 signaling pathway
    100757513 (Rps6kb1)
   04151 PI3K-Akt signaling pathway
    100757513 (Rps6kb1)
   04152 AMPK signaling pathway
    100757513 (Rps6kb1)
   04150 mTOR signaling pathway
    100757513 (Rps6kb1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100757513 (Rps6kb1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    100757513 (Rps6kb1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100757513 (Rps6kb1)
  09149 Aging
   04211 Longevity regulating pathway
    100757513 (Rps6kb1)
   04213 Longevity regulating pathway - multiple species
    100757513 (Rps6kb1)
  09159 Environmental adaptation
   04714 Thermogenesis
    100757513 (Rps6kb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100757513 (Rps6kb1)
   05205 Proteoglycans in cancer
    100757513 (Rps6kb1)
   05207 Chemical carcinogenesis - receptor activation
    100757513 (Rps6kb1)
   05231 Choline metabolism in cancer
    100757513 (Rps6kb1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100757513 (Rps6kb1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100757513 (Rps6kb1)
   05212 Pancreatic cancer
    100757513 (Rps6kb1)
   05225 Hepatocellular carcinoma
    100757513 (Rps6kb1)
   05226 Gastric cancer
    100757513 (Rps6kb1)
   05221 Acute myeloid leukemia
    100757513 (Rps6kb1)
   05224 Breast cancer
    100757513 (Rps6kb1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100757513 (Rps6kb1)
   05163 Human cytomegalovirus infection
    100757513 (Rps6kb1)
   05165 Human papillomavirus infection
    100757513 (Rps6kb1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100757513 (Rps6kb1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100757513 (Rps6kb1)
   01522 Endocrine resistance
    100757513 (Rps6kb1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cge01001]
    100757513 (Rps6kb1)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100757513 (Rps6kb1)
Protein kinases [BR:cge01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   100757513 (Rps6kb1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 100757513
NCBI-ProteinID: XP_027282160
UniProt: A0A8C2LQS5
LinkDB
Position
7:complement(99752941..99793445)
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggcttttacccagcgcctgacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcaggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagctaatactgggaagatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagagcggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagaccggtggaaaactctacctcatccttgagtatctcagtggaggagaacta
tttatgcagttagaaagagagggaatattcatggaagacacagcttgcttttacttggct
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaacatcatgctcaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcgttaatgtacgacatgctgactggagcacctccattcactggagagaacagaaagaaa
acaattgacaaaatcctcaaatgtaaacttaatttgcctccctacctcacacaagaagct
cgagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggatgctggagaagtccaagcacatccatttttcagacacattaactgggaagaactt
ctagctcggaaggtggagcctccctttaagcctctgttgcaatctgaagaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagccccgatgactcaactctc
agtgaaagtgccaaccaggtctttttgggttttacatatgtggctccatctgtacttgaa
agtgtgaaagaaaagttttcctttgaaccaaaaatccgatcacctcgaagatttattggt
agcccacgaacgcctgtcagcccggtcaaattctctcctggggatttctggggacgaggt
gcttcagccagcacggcaaatcctcagacacctgtggaatacccaatggaaacaagtgga
atagagcagatggatgtgacaatgagcggggaggcatcagccccacttccaatccgacag
ccgaactctgggccatacaaaaaacaagcttttcctatgatctccaaacggccggagcat
ctgcgtatgaatctatga

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