Cricetulus griseus (Chinese hamster): 100760469
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Entry
100760469 CDS
T02813
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge04217
Necroptosis
cge04380
Osteoclast differentiation
cge04620
Toll-like receptor signaling pathway
cge04621
NOD-like receptor signaling pathway
cge04630
JAK-STAT signaling pathway
cge04658
Th1 and Th2 cell differentiation
cge04659
Th17 cell differentiation
cge05145
Toxoplasmosis
cge05160
Hepatitis C
cge05161
Hepatitis B
cge05162
Measles
cge05164
Influenza A
cge05165
Human papillomavirus infection
cge05167
Kaposi sarcoma-associated herpesvirus infection
cge05168
Herpes simplex virus 1 infection
cge05169
Epstein-Barr virus infection
cge05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100760469 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100760469 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100760469 (Tyk2)
04621 NOD-like receptor signaling pathway
100760469 (Tyk2)
04658 Th1 and Th2 cell differentiation
100760469 (Tyk2)
04659 Th17 cell differentiation
100760469 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
100760469 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
100760469 (Tyk2)
05160 Hepatitis C
100760469 (Tyk2)
05171 Coronavirus disease - COVID-19
100760469 (Tyk2)
05164 Influenza A
100760469 (Tyk2)
05162 Measles
100760469 (Tyk2)
05168 Herpes simplex virus 1 infection
100760469 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
100760469 (Tyk2)
05169 Epstein-Barr virus infection
100760469 (Tyk2)
05165 Human papillomavirus infection
100760469 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100760469 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cge01001
]
100760469 (Tyk2)
Enzymes [BR:
cge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100760469 (Tyk2)
Protein kinases [BR:
cge01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100760469 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
100760469
NCBI-ProteinID:
XP_027267287
UniProt:
A0A9J7FT87
LinkDB
All DBs
Position
4:complement(133961549..133986132)
Genome browser
AA seq
1186 aa
AA seq
DB search
MVTNMPLCRRRAISGDSRAHGTEAQPLVPTERLMVLLHWAGPEGGEPWVTFSQASLTAED
ICIHIAHKVGITPPCLNLFALYDAQAKVWLPPNHILDTSRDVNLRLYFRMRFYFRNWHGM
NPQEPAVYRYGSPGTETSSERSEQGVHLLDSASFEYLFEQGKYEFMNDVVSLRDLSSEEE
IHHFKNESLGMAFLHLCHLALCRGVPLEEMAREISFKKCIPRSFRQHIRQHNALTRLRLR
RVFRRFLRAFQPGHLSQQVVMVKYLATLERLAPRFGSEHIPVCHLEVLDQPEGDPCYVQN
SGQTTGDPDPELASRVPTHEVLVTGTGGIQWHPLEIQESERGSSRGNLQGNRSGKTVKAP
ETGEQLAKSPGEPPWTYFCDFQDISHVVLEERCVRIHLQDNKCLLLRLCSRAEALSFVAL
VDGYFRLTADSSHYLCHEVAPPRLLTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSH
LYRLILTVAHRKPAPTSGPKGLRLRKFPITQQPGSFVLEGWGRSFDSVGDLRVALQGCSL
RAGEDCFSLHHCCLPRPREISNLVIMRGSSAHTRPPNLSQLSFHRVHQDEITQLSHLGQG
TRTNVYEGLLRVGGPDEGRVDSGCPPEPGGGTGQQLRVVLKILDPSHHDIALAFYETASL
MSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGRVSMTWKMVVAQQLASA
LSYLEDKNLVHGNVCGRNILLARLGLEEGTSPFIKLSDPGVGQSALSREERVERIPWTAP
ECLSGEASSMGTATDMWGFGATLLEICFDGEAPLQGRRPSEKERFYTKQHQLPQPSCPEL
ATLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGISAVNTDSTASDPTVFHKRYLKKIR
ELGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVK
YKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHGQRYIH
RDLAARNVFLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYA
SDVWSFGVTLYELLTYCDSGQSPPTKFIELIGVTQGQMTVLRLTELLERGERLPRPDRCP
CEIYLLMKNCWESEASFRPTFQNLVPILKTAQEKYQGQVPSVFSVC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atggtgaccaacatgcctctgtgtcggcggagagccatctcgggagacagcagggcccat
ggcacagaagctcagcccctggtgcccacagaaagattgatggtgctgctgcactgggct
gggccagagggcggggagccctgggtcacctttagccaggcatctctgactgcggaggac
atctgcatccacattgcacacaaagttggtatcactccaccctgcttgaatctctttgcc
ctctatgatgcacaggccaaggtctggctgcccccaaaccacatccttgacacatcccga
gatgtgaacctaaggctgtatttccgaatgaggttttacttccggaactggcacggcatg
aatccccaggagccagctgtataccgatatggttccccagggacagagacgtcctcagaa
cggtcagagcagggtgtgcatctcttggactctgcttcatttgaatacctctttgagcag
ggaaaatatgagttcatgaatgatgtggtgtctcttcgggacctgtctagtgaggaagag
atccaccactttaagaatgagagcttaggcatggcctttctgcacctctgccaccttgct
ctctgccgtggtgtccccctggaggagatggccagagagatcagctttaagaaatgcatc
cctcgttcattccgccagcacatccgccagcacaatgcgctcacgcgcctgcgtctccgc
agagtcttccggcgattcttgcgggcctttcagcctggtcacctctcccagcaggttgtg
atggttaagtacttggctacactggagcggctggctcctcgatttggctcagagcatata
ccagtgtgtcatctggaggtactggaccagcctgagggagatccctgctatgtccagaac
agtgggcagactactggggacccggacccagagctggccagcagggttcccacccacgag
gtactggtgacaggcaccggaggtatccagtggcatccacttgagatccaggaatctgag
agaggtagcagcagagggaatctccaaggcaaccggtctgggaagacagtgaaggcccct
gagactggagagcagctggcaaagagccctggggagccaccctggacctacttctgtgac
ttccaggacatttcccacgtggtgctagaggaacgctgtgtgcgcatccacctccaggac
aacaagtgcttgctgctgcgcctctgttcccgcgctgaggccctgtcctttgtggccctg
gtggatggctatttccgcctgactgctgactccagccactacctgtgccatgaggtggca
cccccgaggctgttgaccagcatccagaacggcatccacgggcccctgatggatccattt
gtgcaagccaagctgtggccggaggacggcctctacctgattcagtggagcaccagccac
ctttaccgcctgatcctcactgtggctcatcgaaaaccagctcccaccagtggccctaag
ggcctgcgcctccgaaagttccccatcacccagcaacctggatcctttgtgctggaaggc
tggggtcgctcctttgacagtgtgggggaccttcgggtcgccttgcagggctgctcacta
cgggctggggaagactgtttctccttgcaccactgttgcctgccccggccaagagaaatc
tccaacctcgtgatcatgagggggtctagtgcccacacccggcctcctaacctcagccag
ctcagcttccacagggttcaccaggatgaaatcacacagctgtcccacttgggtcaaggc
acaaggaccaatgtgtatgagggccttctaagagtgggaggccctgacgaaggcagagtg
gacagtggatgtccccctgaacctggtgggggcactgggcagcagcttcgagtggtgctt
aaaatcctggaccccagtcaccatgacatcgccttggccttctatgaaacagctagcctc
atgagccaggtgtcacacatgcacctggctttcctgcatggtgtctgcgtgcgcggctca
gagaatatcattgtgacagagttcgtagaacacggtcccctggatgtgtggttacggaga
cagagggggcgagtgtccatgacctggaagatggttgtggctcagcagctagccagcgct
ctcagctacctggaagataagaatctggttcatgggaacgtatgtggccggaacatcctg
ctggcccggctggggctagaggagggtaccagccccttcatcaagctaagtgatcctggt
gtgggccaaagtgccctgtccagggaagagcgggtggagcgcatcccttggacagctcct
gagtgcctgtctggagaggccagtagcatgggtactgctacggacatgtggggcttcggt
gccaccctccttgagatctgctttgatggggaggcacccctgcaaggtcgtcgaccctct
gagaaagaacgattctacacaaagcagcaccagctgcctcagccctcatgcccggagctg
gccacactcacccgccagtgcctgacctacgaaccagcacagcggccatcattccgcacc
attttgcgggacctcactaggctgcagccacagaatctagtgggtatctcagctgtgaac
acagactctacagcatcagatcccactgttttccacaagcgttatttgaaaaagatccgg
gaattgggcgagggtcactttggcaaggtcagcctgtactgctatgatccaaccaatgat
ggcactggcgagatggtggctgtgaaagcccttaaggagggatgtggtccccagctccgc
tcaggctggcagcgggagatcgaaatcctacggaccctgtaccatgaacacattgtcaag
tacaaaggctgctgtgaggaccaaggagagaagtctgtacagctggtcatggagtacgtt
cccctcggcagcctccgggactacctgccgcggcacagcgttgggctggcgcagctcctg
ttattcgcccagcagatctgcgagggcatggcctacctgcacgggcagcgctacatccac
cgagacctcgccgcgcgcaacgtgtttctggacaacgacagactggtcaagattggagac
tttggcctggccaaggcagtgcctgaaggccacgagtactaccgcgtgcgcgaggacggg
gacagcccagtgttctggtatgctccggaatgcctgaaggagtgcaaattttactatgca
tcagatgtctggtccttcggggtgaccttgtatgagctgttgacgtactgtgactctggt
cagagtcccccgacgaaattcattgagctcatcggagtcacccagggccagatgactgtg
ttgaggctcacagagttgctggaacgtggagagaggctgccgaggcctgacagatgtccc
tgtgagatctatctcctcatgaagaactgctgggagtcagaggcctccttccggcccacc
ttccagaatcttgtgcccatcctcaagacagcccaggagaagtaccaaggccaggtgcca
tcagtgttcagtgtgtgctga
DBGET
integrated database retrieval system
