Cricetulus griseus (Chinese hamster): 100768531
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Entry
100768531 CDS
T02813
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X2
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge01521
EGFR tyrosine kinase inhibitor resistance
cge01522
Endocrine resistance
cge04010
MAPK signaling pathway
cge04014
Ras signaling pathway
cge04015
Rap1 signaling pathway
cge04066
HIF-1 signaling pathway
cge04068
FoxO signaling pathway
cge04081
Hormone signaling
cge04114
Oocyte meiosis
cge04140
Autophagy - animal
cge04144
Endocytosis
cge04150
mTOR signaling pathway
cge04151
PI3K-Akt signaling pathway
cge04152
AMPK signaling pathway
cge04211
Longevity regulating pathway
cge04213
Longevity regulating pathway - multiple species
cge04510
Focal adhesion
cge04520
Adherens junction
cge04550
Signaling pathways regulating pluripotency of stem cells
cge04730
Long-term depression
cge04913
Ovarian steroidogenesis
cge04914
Progesterone-mediated oocyte maturation
cge05200
Pathways in cancer
cge05202
Transcriptional misregulation in cancer
cge05205
Proteoglycans in cancer
cge05214
Glioma
cge05215
Prostate cancer
cge05218
Melanoma
cge05224
Breast cancer
cge05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100768531 (Igf1r)
04014 Ras signaling pathway
100768531 (Igf1r)
04015 Rap1 signaling pathway
100768531 (Igf1r)
04066 HIF-1 signaling pathway
100768531 (Igf1r)
04068 FoxO signaling pathway
100768531 (Igf1r)
04151 PI3K-Akt signaling pathway
100768531 (Igf1r)
04152 AMPK signaling pathway
100768531 (Igf1r)
04150 mTOR signaling pathway
100768531 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
100768531 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100768531 (Igf1r)
04140 Autophagy - animal
100768531 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
100768531 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100768531 (Igf1r)
04520 Adherens junction
100768531 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
100768531 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100768531 (Igf1r)
04914 Progesterone-mediated oocyte maturation
100768531 (Igf1r)
09156 Nervous system
04730 Long-term depression
100768531 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
100768531 (Igf1r)
04213 Longevity regulating pathway - multiple species
100768531 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100768531 (Igf1r)
05202 Transcriptional misregulation in cancer
100768531 (Igf1r)
05205 Proteoglycans in cancer
100768531 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100768531 (Igf1r)
05214 Glioma
100768531 (Igf1r)
05218 Melanoma
100768531 (Igf1r)
05215 Prostate cancer
100768531 (Igf1r)
05224 Breast cancer
100768531 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100768531 (Igf1r)
01522 Endocrine resistance
100768531 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cge01001
]
100768531 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cge04090
]
100768531 (Igf1r)
Enzymes [BR:
cge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100768531 (Igf1r)
Protein kinases [BR:
cge01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100768531 (Igf1r)
CD molecules [BR:
cge04090
]
Proteins
100768531 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
B2
Motif
Other DBs
NCBI-GeneID:
100768531
NCBI-ProteinID:
XP_027263930
UniProt:
A0A8C2N2R2
LinkDB
All DBs
Position
3:complement(128980421..129272802)
Genome browser
AA seq
1371 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGD
LCPGTLEEKPMCEKTTINNEYNYRCWTTNQCQKMCPSVCGKRACTENNECCHPECLGSCH
TPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHD
GECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYS
FYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLRFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSRNTTVADTYNITDPEELETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELELELEPENMESVPLDPSASSVSLPL
PERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
NT seq
4116 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcactgtgggggctcgtgtttctctct
gccgcgctctcgctgtggccgacgagtggagaaatttgtgggcccggcattgacatccgc
aatgactaccagcagctgaagcgcctggaaaactgcacagtgattgagggcttcctccac
atcctgctcatctccaaggccgaggactaccgaagctaccgcttccccaagctcacggtc
atcactgagtacttgctgctgtttcgagtggccggcctcgagagcctgggagacctcttc
cccaaccttacggttatccgtggctggaaactcttctacaactacgcactggtcatcttt
gagatgaccaatctcaaggatattggactttataatctgagaaacattacacggggggcc
atcaggattgagaagaacgcagacctctgttacctctccaccatagactggtctctcatc
ttggatgcagtgtctaataactacattgtgggcaacaagcccccaaaggaatgtggggac
ctgtgtccagggaccttggaggagaagcccatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaatcaatgccagaaaatgtgcccaagtgtgtgcgga
aagcgagcgtgcaccgagaacaacgaatgctgccacccagagtgcctaggcagctgccat
acacctgacgacaacacaacctgtgtggcctgccgacactactactacaaaggcgtgtgt
gtgcctgcctgcccacctggcacctacaggttcgagggctggcgctgtgtggaccgcgat
ttctgcgccaacatccccaacgctgagagcagtgactcagatggctttgtcatccacgat
ggcgagtgcatgcaagaatgtccctcaggcttcatccgcaacagcacccagagcatgtac
tgtatcccctgtgaaggcccctgcccaaaagtctgtggcgatgaagaaaagaaaacaaaa
accatcgactcggttacgtcggctcagatgctccaaggatgcaccatcttgaagggcaat
ttacttattaatatccggcggggcaataacattgcctcagaacttgagaacttcatgggg
ctcatcgaggtagtgactggctatgtgaagatccgccattcccatgctttggtctccttg
tccttcctgaagaaccttcgtctaatcttaggagaggagcagctggaagggaactactcc
ttctatgtcctggacaaccagaacttgcagcagctgtgggactggaaccaccggaacctg
accgtcaggtcggggaagatgtactttgctttcaatcccaagctgtgtgtctctgaaatt
taccgcatggaggaagtaacaggaacaaagggccgccagagcaaaggggacataaacacc
aggaacaatggagagcgagcttcctgtgaaagcgacgttctccgtttcacctccaccacc
acctcaaagaaccggatcatcataacatggcaccggtaccggcccccagattacagggat
ctcatcagcttcacggtttactacaaggaggcaccctttaaaaatgttacggaatatgat
gggcaggatgcctgtggctccaacagctggaacatggtggatgtggacctacctcccaac
aaggagggggagcctggcattttactgcatgggctgaagccctggacccagtatgccgtc
tatgtcaaggctgtgaccctcaccatggtggaaaacgaccatatccgtggggccaaaagt
gaaatcttgtacattcgcaccaatgcttcagttccttccattcccctagatgtactttcg
gcctcaaactcttcttctcagctgattgtgaagtggaatcctccaactctgcccaatggt
aacttgagttactacattgtaaggtggcagcgacagccacaggatggctacctgtaccgg
cacaactactgctccaaagacaaaatacccatcagaaagtatgcggatggcaccattgat
gtggaagaggtgacagagaatcccaagacagaagtgtgtggtggtgacaaagggccttgc
tgtgcttgtcccaaaactgaagccgagaagcaggccgagaaggaagaggccgagtaccgc
aaagtctttgagaatttcctgcacaattccatcttcgtgcccagacccgaaaggaggcgg
agagatgtcatgcaagtagccaacaccaccatgtctagccgaagcaggaacaccacagtg
gctgacacctacaatatcacagatccagaagaactcgagacagagtaccctttctttgag
agcagagtagataacaaggagagaactgtcatctccaaccttcggcctttcactttgtac
cgcattgatatccacagctgcaaccacgaagccgagaagctgggctgcagtgcctccaac
tttgtctttgcgagaaccatgcctgcagaaggagcagatgacattcctggaccagtgacc
tgggagccaagacctgaaaactccatctttttaaagtggccagaacctgagaaccccaac
ggattgattctaatgtatgaaataaagtatggatcacaagttgaggatcagcgggaatgt
gtgtccagacaggaatacaggaagtacggaggggccaagcttaaccggctaaacccaggg
aactatacagcccggattcaggccacgtctctctctggcaatgggtcttggacagatcct
gtgttcttctatgtcccagccaagacgacatatgagaatttcatgcacctgataattgct
ctgccggtcgccatcctgctgattgtggggggactggtcatcatgctgtatgtcttccat
aggaagagaaataacagcaggttgggcaatggagtgctgtatgcctctgtgaaccccgag
tatttcagtgcagcggatgtgtacgtgcccgatgaatgggaggtagctcgagagaagatc
accatgaaccgggagcttggacaagggtcctttgggatggtctatgaaggagtggccaag
ggagtggtcaaggatgaacctgaaaccagagtagccatcaagacagtaaatgaggctgca
agtatgcgtgaaagaatcgagtttctcaacgaggcttcagtgatgaaggagttcaactgt
caccatgtggtccggttgctgggggtggtgtcccaaggccagcctaccctggtcatcatg
gaactaatgacacgtggggatctcaaaagttatctccggtctctaaggccagaagtggag
caaaataatctagtcctaattcctccgagtttaagcaagatgatccagatggctggagag
attgcagatggcatggcttacctcaacgccaacaagttcgtccacagagaccttgctgct
cggaactgcatggtagctgaagatttcacagtcaaaattggagattttggtatgacacga
gatatctacgagacagactactaccggaaaggagggaaggggctgctgcctgtgcgctgg
atgtctcctgagtccctcaaggacggagtcttcaccactcactcagatgtctggtccttt
ggggtcgtcctctgggagattgctacactggctgagcagccataccaaggcttgtccaat
gagcaagttcttcgcttcgtcatggagggcggccttctggacaagccggacaattgccct
gacatgctgtttgaactcatgcgcatgtgctggcagtacaaccctaagatgaggccctcc
ttcctggagatcattggcagcatcaaggatgagatggagcccagctttcaggaggtctcc
ttctactacagcgaggagaacaagcctcctgagccagaagagctggagctggaactggag
cccgagaacatggagagcgtaccgctggacccctcggcctcctcagtctccctgcctctg
ccagaaagacactcaggacacaaggccgagaatggcccaggccctggagtactggttctc
cgtgccagtttcgatgagcgacagccttacgctcacatgaacgggggacgagccaacgag
agggctttgcctctgccccagtcttcaacctgctga
DBGET
integrated database retrieval system
