Cricetulus griseus (Chinese hamster): 100769961
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Entry
100769961 CDS
T02813
Symbol
Nos3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X3
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00220
Arginine biosynthesis
cge00330
Arginine and proline metabolism
cge01100
Metabolic pathways
cge04020
Calcium signaling pathway
cge04022
cGMP-PKG signaling pathway
cge04066
HIF-1 signaling pathway
cge04071
Sphingolipid signaling pathway
cge04151
PI3K-Akt signaling pathway
cge04370
VEGF signaling pathway
cge04371
Apelin signaling pathway
cge04611
Platelet activation
cge04915
Estrogen signaling pathway
cge04921
Oxytocin signaling pathway
cge04926
Relaxin signaling pathway
cge04931
Insulin resistance
cge04933
AGE-RAGE signaling pathway in diabetic complications
cge05415
Diabetic cardiomyopathy
cge05417
Lipid and atherosclerosis
cge05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100769961 (Nos3)
00330 Arginine and proline metabolism
100769961 (Nos3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100769961 (Nos3)
04371 Apelin signaling pathway
100769961 (Nos3)
04066 HIF-1 signaling pathway
100769961 (Nos3)
04020 Calcium signaling pathway
100769961 (Nos3)
04071 Sphingolipid signaling pathway
100769961 (Nos3)
04022 cGMP-PKG signaling pathway
100769961 (Nos3)
04151 PI3K-Akt signaling pathway
100769961 (Nos3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100769961 (Nos3)
09152 Endocrine system
04915 Estrogen signaling pathway
100769961 (Nos3)
04921 Oxytocin signaling pathway
100769961 (Nos3)
04926 Relaxin signaling pathway
100769961 (Nos3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100769961 (Nos3)
05418 Fluid shear stress and atherosclerosis
100769961 (Nos3)
05415 Diabetic cardiomyopathy
100769961 (Nos3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100769961 (Nos3)
04933 AGE-RAGE signaling pathway in diabetic complications
100769961 (Nos3)
Enzymes [BR:
cge01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100769961 (Nos3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100769961
NCBI-ProteinID:
XP_027284253
UniProt:
A0A8C2LZU5
LinkDB
All DBs
Position
8:complement(98139509..98161381)
Genome browser
AA seq
1202 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCSKQGPASPAPEPSQAPASPAPAQPAPDHSPPLTR
PPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQNRPTEGPSPTE
QLLGQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA
PRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHVKYATNRGNLRSAITVFPQRCPGRGDF
RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWAPGNGRFDVLPLLLQAPDEPPE
LFTLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSE
IGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH
AATASFMKHLESEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK
GSAAKGTGIARKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL
FRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP
RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC
AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAAR
DIFSPKRSWKRQRYRLSTQAESLQLLPGLTHVHRRKMFQATILSVENLQSSKSTRATILV
RLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSAEPVAVEQLEKGSPGGPP
PGWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYE
EWKWFRCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVLA
YRTQDGLGPLHYGVCSTWLSQLKAGDLVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPF
RGFWQERLHDIEIKGLQPAPMTLVFGCRCSQLDHLYRDEVLDAQKRGVFGHILTAFSRDP
GSPKTYVQDLLRTELAAEIHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGDMELDE
AGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPGPETP
AS
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggtcaggagcctgggccaccctgtggcctagggcttggg
ctgggtctagggctgtgcagcaagcagggcccagcctctccagcacccgagcctagccag
gcaccagcatccccagcccccgcccaaccagcaccagaccacagccccccactaacccgg
cccccagagggacccaagtttcctcgagtgaagaactgggaagtaggcagtatcacctat
gacaccctcagtgcccaggctcagcaggatgggccctgcaccccaagacgctgcttagga
tcactggtatttccaaggaagttacagaaccggcctaccgagggcccttcacccactgag
cagctactgggtcaggcccgggacttcatcaatcagtactacaactccatcaaaaggagt
ggttcccaggctcatgaacagcgactacaggaggtagaggctgaggtggcagccacaggc
acctaccagctccgggagagtgagctagtgtttggggccaagcaggcctggcgcaacgcc
ccccgctgtgtgggccggatccagtggggaaagcttcaggtatttgatgcccgggactgc
aggaccgcacaggaaatgttcacctatatctgcaatcatgttaagtatgcaacaaaccga
ggcaatcttcgttcagccatcacagtgttccctcagcgatgccctggcaggggagacttc
cggatctggaacagccagctggtgcgctatgcaggctacaggcagcaggatggctctgtg
cgaggggaccctgccaatgtggagatcactgagctctgtatccaacatggctgggcccca
ggaaatggccgttttgatgtgctacccctgctactccaggctccagatgagcccccagaa
ctcttcactctgcctccagagctggtcctcgaggtgcctctggagcaccccacgctagag
tggtttgctgcccttggcctgcgttggtacgccctcccagctgtgtccaacatgctgctg
gaaattggtggcctggagttccctgctgcccctttcagtggctggtacatgagctcagag
attggcatgagggacctgtgtgacccccaccgctacaacattcttgaggatgtggctgtc
tgcatggatctagacaccaggacgacctcatcactgtggaaagacaaggcagcagtggaa
attaacgtggccgtactgcacagttaccagctggccaaagtgaccattgtggaccaccat
gctgccacagcctccttcatgaagcacttggagagtgagcagaaggccagagggggctgc
cctgccgattgggcctggatcgtgcctcccatctcaggcagcctcactcctgtcttccat
caagagatggtcaactatttcctgtcccctgccttccgctaccagcctgacccctggaag
ggaagtgccgcaaagggcacgggcatcgccaggaagaagacctttaaggaagtggccaat
gcagtgaagatctctgcctcactcatgggcaccgtgatggcgaagcgtgtgaaggcaact
atcctgtatggttcggagactggccgggcccagagctatgcacagcagctggggagactc
ttccggaaggcatttgatccccgggtcctgtgcatggatgagtatgatgtggtgtccctg
gagcatgaggcactggtgttggtggtgaccagcacatttgggaatggggatcccccggag
aatggagagagcttcgcggcagcattgatggagatgtcaggtccctacaacagctcccct
cggcctgagcagcacaagagttacaaaattcgattcaacagtgtctcctgctcagatcca
ctggtatcctcttggcggcgtaaaaggaaggagtccagtaacacagacagcgcaggggcc
ctgggcaccctcaggttctgtgtgtttgggctgggctcccgagcatacccccacttctgt
gcctttgctcgggcagtggacacaaggctggaggagctgggtggggaacggctactgcag
ctgggccaaggtgatgagctctgtggccaggaggaggctttccgaggctgggcccaggca
gccttccaggctgcctgtgagaccttctgtgtgggagaagatgccaaggctgctgcccga
gacatctttagccccaaacgcagctggaagcgccagaggtaccggctgagtacccaggct
gagagcctgcagttgctaccagggctgacccatgtgcataggcggaagatgttccaggct
acgatcctctctgtggaaaacctacagagcagcaaatccacccgagccacaatcctggtg
cgtctggacactggtggccaagagggtctacagtaccagccaggggaccacataggtgtg
tgcccacccaaccgacctggcctagtggaggcactgctaagcagagtggaggaccctccg
ccatccgcagaacctgtggccgtggagcaactggagaagggcagccctggtggccctccc
cccggctgggtgcgggacccccggctgcccccgtgtacactgcgccaggctctcaccttc
ttcctggacatcacttccccgccaagccctcgcctccttcgactgctcagcaccctggca
gaagagtccagtgaacagcaggagctagaggccctcagccaggacccccggcgctatgaa
gagtggaagtggtttcgctgccccacactgctggaggttctggagcagttcccatcagtg
gcattgcctgcccctctgatcctcactcagctgcccctgctccagccccggtactactct
gtcagctcagcacccagcgcccacccaggagagatccacctcaccgtagccgtgctggca
tacagaacccaggatgggctgggccctctgcattatggtgtgtgttccacatggctgagc
caactcaaggcaggagacctggtgccctgcttcatcaggggggctccctcctttcggctg
ccacctgatcccaacttgccctgcattctggtgggtccagggactggcattgcacccttc
cggggattctggcaggagcgattgcatgacattgaaatcaaagggctgcagcccgccccc
atgactctggtgtttggctgtcgatgctcccaactcgaccatctctaccgggatgaggta
ctggatgcccagaagcgcggggtgtttggacacatcctcaccgccttttccagggatcct
ggcagtcctaagacctacgtgcaagacctgctgaggaccgagctggcggccgagatccac
cgcgtgctgtgcctcgagcaaggacacatgtttgtctgcggcgatgtcactatggcaacc
agcgtcctgcagacggtgcaacggatcctggcgacagagggcgacatggagctggacgag
gccggtgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaggacattttcgga
ctcacgttgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcag
gagcgacagctgcggggtgccgtgccctggtccttcgacccgcccggcccagaaaccccc
gcttcttga
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