Cricetulus griseus (Chinese hamster): 100770041
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Entry
100770041 CDS
T02813
Symbol
Top2b
Name
(RefSeq) DNA topoisomerase 2-beta isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100770041 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
cge03032
]
100770041 (Top2b)
03036 Chromosome and associated proteins [BR:
cge03036
]
100770041 (Top2b)
Enzymes [BR:
cge01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100770041 (Top2b)
DNA replication proteins [BR:
cge03032
]
Eukaryotic type
DNA Topoisomerases
100770041 (Top2b)
Chromosome and associated proteins [BR:
cge03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100770041 (Top2b)
Centrosome formation proteins
Centriole proteins
100770041 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
Motif
Other DBs
NCBI-GeneID:
100770041
NCBI-ProteinID:
XP_027245183
UniProt:
A0A098KXG8
LinkDB
All DBs
Position
1
Genome browser
AA seq
1612 aa
AA seq
DB search
MAKSSLAGADGALTWVNNAAKKEELETSNKNDSSKKLSVERVYQKKTQLEHILLRPDTYI
GSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP
ESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN
IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLAKFKMEKL
DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE
LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSV
KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI
LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS
GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL
RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS
IPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL
AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN
ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL
AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD
DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPN
YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP
ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK
YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK
DLIQMLVQRGYESDPVRAWKEAQEKAAEEEDTQNQHDDSSSDSGTPSGPDFNYILNMSLW
SLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS
GKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTPVVKV
EFDEEFSGTPVEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPTSAGKPNAKKVKKR
NPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEEEDADDDDDNNDLE
ELKVKASPITNDGEDEFVPSDGLDKDEYAFSPGKSKATPEKSSHDKKSQDFGNLFSFPSY
SQKSEDDSAKFDSNEEDTASVFTPSFGLKQTDKVPSKTVAAKKGKPPSDTAPKAKRAPKQ
KKVVETVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKPSKTASKKPK
KTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4839 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccagcctcgcgggtgctgatggggcgctgacctgggtgaacaatgctgca
aaaaaggaagagctggaaacctcaaacaaaaatgattcttcaaagaagttgtctgttgag
agagtgtaccagaagaagacccagcttgaacatattctccttcgtcctgatacatacatt
ggatcagtagaaccattgacccagttaatgtgggtgtatgatgaagatgtaggaatgaac
tgcagagaggttacctttgttccaggcttatacaagatctttgatgaaattttggtcaat
gctgctgacaataagcagagggacaagaacatgacctgtattaaggtttctattgatcct
gaatctaatattataagcatttggaataatgggaaaggcattccagtagtagaacacaaa
gtagagaaagtttatgttcctgctttaatctttggacagcttttaacatcgagtaattat
gatgatgatgagaaaaaagttacagggggccgtaatggctatggtgcaaaactttgtaat
atttttagtacaaagtttacagtagaaacggcttgcaaagaatacaaacatagttttaag
cagacatggatgaataatatgatgaagacttctgaagccaaaattaaacattttgatggt
gaagattatacatgtataacattccaaccagatctagccaagtttaagatggaaaaactt
gataaggatattgtggccctcatgactagaagagcatatgatttggctggttcatgtaaa
ggggtcaaggtcatgtttaatggaaagaagttgcctgtaaatggatttcgcagctatgta
gacctttatgtaaaagacaaattagatgaaactggagtagccctcaaagttattcatgaa
cttgcaaatgaaagatgggatgtttgtctcaccttgagtgagaaagggttccagcagatc
agctttgtgaatagtattgcaaccacaaaaggtggacggcatgtggattatgtagtagat
caagttgttggtaaactgatcgaagtagttaagaaaaagaacaaagctggtgtatcagtg
aagccatttcaagttaaaaaccatatatgggtttttattaattgtcttattgagaatcca
acctttgattctcaaactaaggaaaacatgactctgcagcccaaaagttttgggtccaaa
tgccaactgtcagaaaaattttttaaagcagcctctaattgtggcattgtagaaagcata
ttgaactgggtgaaatttaaggctcagactcagctgaataagaagtgttcatcagtaaag
tacagtaagatcaaaggcattcccaaactggatgatgccaatgatgctggtggcaaacat
tccctggagtgtacattgatattaacagagggagactctgccaaatcgctagctgtatct
ggattaggtgtgattggcagggacagatacggagtcttcccactgaggggtaaaattctc
aatgttcgagaagcgtctcataaacagattatggaaaatgcggaaataaacaatattatt
aaaatagttggtttacagtataagaaaagttatgatgatgcagaatctttgaaaacctta
cgttatggaaagattatgattatgactgatcaggatcaagatggttctcacatcaaaggc
cttctaatcaattttattcatcacaattggccatcacttctgaagcatggttttcttgaa
gaattcattactcccattgtaaaggcaagcaaaaataagcaggaactttccttttatagt
attcctgaatttgatgaatggaaaaaacatatagaaaaccagaaagcctggaaaataaaa
tactacaaaggattgggtaccagtacagctaaagaagcaaaggaatattttgctgatatg
gaaaggcatcgtattttgtttagatatgctggtcctgaagatgatgctgccattaccttg
gcatttagtaagaagaagattgatgacagaaaagaatggttaacaaactttatggaggat
cggagacagcgtaggttacatggcctaccagagcaatttttatatggcacagcaacaaaa
catttgacatacaatgatttcatcaacaaggaattgattctcttctcaaattcagacaat
gagagatctataccatctcttgtggatggcttcaaaccaggccaacgaaaagttttgttt
acctgtttcaagaggaatgataaacgtgaagtaaaagtcgcccagctggctggatctgtt
gctgaaatgtctgcctatcatcatggagaacaagcattgatgatgactattgtaaatttg
gctcagaattttgtgggcagtaacaacattaacttgcttcagcccattggtcagtttgga
actcggcttcatggtggcaaagatgctgcaagccctcgttatattttcacaatgttaagc
tctctggcaagactgctttttccagctgtggatgataacttgcttaagttcctttatgat
gataatcagcgtgtagagcccgagtggtatatccccataatccctatggttttgattaat
ggtgcggagggcattggtactggatgggcttgtaaactgcctaactatgatgctagagaa
attgtgaacaatgtcagacggatgctagacggtttggaccctcatcccatgcttccaaac
tacaaaaacttcaaaggcaccatccaggaacttggtcagaaccagtatgctgtcagtggg
gagatatttgtggtggatagaaacactgtagagattacagaacttccagttagaacttgg
actcaggtatacaaggagcaggtcctagaacctatgcttaacggaacagataaaacacca
gcactaatttctgattacaaagaatatcatactgatacaactgtgaaatttgtagtgaaa
atgacagaagaaaaacttgcacaagcagaagctgctggactgcataaagtttttaaactt
caaactactcttacttgcaattccatggtactctttgatcatatgggatgtctgaagaag
tatgaaactgtgcaagacattctgaaggaattctttgatttacgattaagttattatggt
ttacgaaaggagtggcttgtaggaatgttgggagcagaatctacaaagcttaataatcaa
gcccgtttcattttagagaagatacaagggaaaattactattgagaataggtcaaagaaa
gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgagagcgtggaaa
gaagcacaagaaaaggcagcagaagaggaagacacacaaaaccaacatgacgatagttcc
tctgactcaggaactccttcaggccctgattttaattatattttaaatatgtctctatgg
tctcttactaaagaaaaagttgaagaactcattaagcagagagatacaaaagggcgagaa
gttaatgatctcaaaaggaagtctccttcagatctttggaaagaagatttagcagcattt
gttgaagaactggataaagtagaagcacaagaacgagaagatattctggcaggaatgtct
ggaaaagcaataaaaggtaaagttggcaaaccgaaggtaaagaaacttcagctggaggag
acgatgccctcaccttatgggagaagaattgttcctgaaattactgctatgaaagcagat
gccagtagaaaattgctgaagaagaagaagggtgatcctgataccccagtagtgaaagta
gaatttgatgaagaatttagtggaacaccagtagaaggtacaggagaagagacattgacc
ccatcagctcctgtaaataaaggtcccaaacccaaaagggagaaaaaggagcctggtacc
agggttagaaaaacacccacatcagctggtaaaccgaatgcaaagaaagtgaagaaacgg
aacccttggtcagatgatgagtccaagtcagagagtgacttggaagaaacagaacctgtg
gttattccaagagattctctgctccggagagcagctgctgaaagacctaagtacaccttt
gatttctcagaagaggaggaggaggatgctgatgatgatgatgacaataatgatttagaa
gaactgaaagttaaggcatctcccataacaaatgatggggaagatgaatttgttccttca
gatggcttagataaagatgagtatgctttttctccaggcaaatcaaaagctactccagaa
aaatcatcacatgacaaaaaaagtcaggattttgggaatctcttttcatttccttcatat
tctcagaagtcagaagatgattcagctaaatttgatagtaatgaggaagatactgcttct
gtttttacaccatcatttggtctgaagcaaacagataaagttccaagtaaaacagttgct
gctaaaaagggtaaaccaccttcagatacagcccctaaggccaagagagcacctaaacag
aagaaagttgtagagactgtaaactctgactcagattctgaatttggcattccaaagaag
actacaacaccaaaaggtaaaggccgaggggccaagaaaaggaaagcatcaggctcagaa
aatgaaggtgattataaccctgggaggaaaccatctaaaacagccagcaagaaaccgaag
aaaacatcttttgatcaggattcagatgtagacatctttccctcagacttcacttctgaa
ccacctgctctgccacggactggtcgggctaggaaagaagtaaaatattttgcagaatct
gatgaagaagaagatgttgattttgcaatgtttaattaa
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