KEGG   Cricetulus griseus (Chinese hamster): 100770074
Entry
100770074         CDS       T02813                                 
Symbol
Rock1
Name
(RefSeq) rho-associated protein kinase 1 isoform X3
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge04022  cGMP-PKG signaling pathway
cge04024  cAMP signaling pathway
cge04062  Chemokine signaling pathway
cge04071  Sphingolipid signaling pathway
cge04270  Vascular smooth muscle contraction
cge04350  TGF-beta signaling pathway
cge04360  Axon guidance
cge04510  Focal adhesion
cge04520  Adherens junction
cge04530  Tight junction
cge04611  Platelet activation
cge04670  Leukocyte transendothelial migration
cge04810  Regulation of actin cytoskeleton
cge04921  Oxytocin signaling pathway
cge05135  Yersinia infection
cge05163  Human cytomegalovirus infection
cge05200  Pathways in cancer
cge05205  Proteoglycans in cancer
cge05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:cge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    100770074 (Rock1)
   04071 Sphingolipid signaling pathway
    100770074 (Rock1)
   04024 cAMP signaling pathway
    100770074 (Rock1)
   04022 cGMP-PKG signaling pathway
    100770074 (Rock1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100770074 (Rock1)
   04520 Adherens junction
    100770074 (Rock1)
   04530 Tight junction
    100770074 (Rock1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100770074 (Rock1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100770074 (Rock1)
   04670 Leukocyte transendothelial migration
    100770074 (Rock1)
   04062 Chemokine signaling pathway
    100770074 (Rock1)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    100770074 (Rock1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100770074 (Rock1)
  09158 Development and regeneration
   04360 Axon guidance
    100770074 (Rock1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100770074 (Rock1)
   05206 MicroRNAs in cancer
    100770074 (Rock1)
   05205 Proteoglycans in cancer
    100770074 (Rock1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100770074 (Rock1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100770074 (Rock1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cge01001]
    100770074 (Rock1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cge03036]
    100770074 (Rock1)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     100770074 (Rock1)
Protein kinases [BR:cge01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   100770074 (Rock1)
Chromosome and associated proteins [BR:cge03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    100770074 (Rock1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Cortex-I_coil Pkinase_C APH
Other DBs
NCBI-GeneID: 100770074
NCBI-ProteinID: XP_027259436
UniProt: A0A9J7JGR2
LinkDB
Position
2:235984439..236092847
AA seq 1354 aa
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANASENRTSSSV
DKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESV
VSQIEKEKMLLQHRINEYQRKMEQENEKRRNVENEVSTLKDQLEDLRKVSQSSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQAD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMYEMEKKL
KEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLTLQLEQES
NKRLLLQNELKTQAFETDNLKGSEKQMKQEINTLLEAKRLLEFEFAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLRKIQELQSEKETLSTQLDLAETKAE
SEQLARGILEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNTMLTKDIEILRKENE
ELNERMRTAEEEYKLKKEEEINNLKVAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSIASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDIEMEPVQQGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTMSTRSTANQSFRKVVKNTSGKTS
NT seq 4065 nt   +upstreamnt  +downstreamnt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaagtcggaagtaaattcagattgcttgctggatggattagatgctttggtttatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttctaagcagatataaa
gacacaataaataaaattagagatttacggatgaaagccgaagattatgaggtagtgaag
gtgattggcagaggtgcatttggagaagttcaattggtaagacataaatccaccaggaag
gtgtatgctatgaagcttctcagcaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagggacattatggcttttgccaacagtccttgggttgttcagcttttt
tatgcattccaagatgatcggtatctctacatggtgatggaatacatgcctggtggagac
cttgtaaacctgatgagcaactatgacgtccctgagaaatgggcacgattctatactgca
gaagtagttctcgcattggatgcaattcattccatgggttttattcatagagatgtaaag
cctgataacatgctgctggataagtctggacatttgaagttagcagattttggtacttgc
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattat
atttcacctgaagtattaaaatcccaaggtggtgatggctattatggacgagagtgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctttggttggaacttacagtaaaattatgaaccataaaaattcacttactttccct
gatgataatgacatatcaaaagaagcaaaaaatctcatttgtgccttccttaccgacaga
gaggtgagattgggcagaaatggtgtagaggaaatcaaacgtcatctcttcttcaaaaat
gatcagtgggcttgggaaacactccgagacactgtagcaccagttgtacctgatttaagt
agtgacattgataccagtaattttgatgacttggaagaagacaaaggagatgaagaaaca
tttcctattcctaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatacttaccttcagctaatgccagtgaaaatagaaccagctccagtgtg
gataaaagcttgcaggaaagtttacagaaaacaatctacaagcttgaagaacaactgcat
aatgaaatgcaactaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggacgaagaggggaatcaaagaagaaatctagagtctgtg
gtatctcaaattgagaaggaaaaaatgttgctacaacatagaattaatgaataccaaaga
aaaatggagcaggaaaatgagaagagaagaaatgtagaaaatgaagtttctacactaaag
gaccagttggaagacttacggaaagtgagtcagagctcacagcttgctaacgagaagctg
gcacagttacagaagcagttagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagtcacacagagatgagcaagtcaattagtcagctagagtcc
ttgaacagagaattacaggagagaaacagaattttagagaattccaagtcacaagcagac
aaagattactaccagctgcaagctgtattggaagctgagcgaagagacagagggcatgat
tctgagatgattggagacctacaagcacgaattacatctttacaagaggaggtgaaacat
cttaaacataatcttgaaagggtagaaggagaaagaaaagaggctcaagacatgcttaat
cactcagaaaaggaaaagaataatttagagatagatttgaactacaaactcaagtctttg
caacagaggttagaacaagaagtaaatgaacacaaagtaactaaagcgaggttaactgac
aagcaccagtctatagaagaggcaaagtctgttgccatgtatgaaatggaaaaaaagctg
aaggaagagagagaagctcgagaaaaggctgaaaatcgagttgttgagactgagaaacag
tgctctatgctagatgttgatctgaaacaatctcagcagaagctagaacatttgactgaa
aataaagaaaggatggaagatgaagttaagaatctcacactgcagctggaacaggaatca
aataaacggctattgttacagaatgaattgaagactcaagcatttgaaacagacaattta
aaaggttcagaaaaacagatgaaacaggaaataaatactttattggaagcaaaaagattg
ttagaatttgagtttgctcagcttacaaagcaatacagaggaaatgaggggcaaatgcga
gagttacaagaccaacttgaagctgagcagtatttttctacactttataaaacccaggta
aaggaactcaaagaagaaattgaagaaaaaaacagagaaaatttaaggaaaatacaggag
ctgcaaagtgaaaaagaaactctttctactcagttggatctagcagaaacaaaagctgag
tctgagcaattggctcgaggaattctggaagaacagtattttgagttgactcaagaaagc
aagaaagctgcttcaagaaatagacaagagattacagataaagatcacactgttagccgg
cttgaagaaacaaacaccatgctaaccaaagatattgaaatactaagaaaagaaaacgaa
gagctaaatgaaaggatgaggacagcagaagaagaatataagttgaagaaagaggaagaa
ataaataatcttaaggttgcctttgaaaagaatatcagtactgaacggaccctgaaaaca
caggctgttaacaaattggcagaaataatgaatcgcaaagattttaaaattgataggaag
aaagctaatacgcaagatttgagaaaaaaagaaaaggaaaataggaagctacaactggaa
cttaaccaagaaagagagaaatttaaccaaatggttgtgaaacaccagaaggagctgaac
gacatgcaagcgcaattggtagaagaatgtacacacagaaatgaacttcaaatgcaattg
gctagcaaagagagtgatattgagcagttgcgtgcaaaacttttggacctttcggattca
accagcattgctagttttcctagtgctgatgagactgatggaaaccttccagagtcaaga
attgaaggttggctttctgtaccaaatagaggaaatatcaaaagatatggctggaaaaaa
cagtatgttgtggtaagcagcaaaaaaatcttgttctataatgatgaacaagataaggaa
caatccagtccatcgatggtgttggacatagataaattgtttcatgtccgaccggtaacc
caaggagatgtgtacagagctgaaactgaagaaattcctaaaatattccagatcctgtat
gcaaatgaaggtgaatgtagaaaagatatagaaatggaaccagttcaacaaggtgaaaaa
accaacttccagaaccacaagggccatgaattcattcctacactctaccacttccctgcc
aactgtgaggcctgtgccaaacctctgtggcatgtatttaagccaccccctgccctagag
tgtcgaagatgccatgttaagtgccacagggatcacctagacaagaaagaggacttgatt
tccccgtgcaaagtaagttacgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaactcatctggtaaagaagattcctaagaaccca
ccatctggctttgtccgcgcctctcctcgaacaatgtcgacaagatccactgcaaatcag
tcgttccggaaagtggtcaaaaatacatctggaaaaactagttaa

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