Cricetulus griseus (Chinese hamster): 100774234
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Entry
100774234 CDS
T02813
Symbol
Bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X2
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00280
Valine, leucine and isoleucine degradation
cge00640
Propanoate metabolism
cge00785
Lipoic acid metabolism
cge01100
Metabolic pathways
cge01210
2-Oxocarboxylic acid metabolism
Module
cge_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
100774234 (Bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100774234 (Bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100774234 (Bckdha)
Enzymes [BR:
cge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
100774234 (Bckdha)
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Gene cluster
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100774234
NCBI-ProteinID:
XP_027286177
UniProt:
A0A9J7GHZ8
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All DBs
Position
9:9464031..9491129
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AA seq
438 aa
AA seq
DB search
MAAAMWRQSRGLAALLSLRRPGARGLARSHPSRQQQQFPSLDDKPQFPGASAEFVDKLEF
IQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKFYRSMTLLNTMDRILYESQRQGR
ISFYMTNYGEEGTHVGSAAALDRTDLVFGQYREAGVLMYRDYPLELFMAQCYGNVNDPGK
GRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRIVICYFGEGAASEGDAH
AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGILSIRVDGNDVFAVY
NATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRQY
LLNQGCWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPNLLFSDVYQEMPAQLRRQQESL
VRHLQTYGEHYPLDHFDK
NT seq
1317 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcgatgtggagacagagccggggcctggctgctctcctgtcgctgcggcgg
cctggggcgcggggcttggctagatcccaccccagcaggcagcagcagcagttcccatcc
ctggacgacaagccccagttcccgggggcctcggcagagtttgtagacaagcttgagttc
atccaacccaatgtcatctccggcatccccatctaccgggtcatggaccgccagggccag
atcatcaaccccagtgaagacccccatctgccccaggaggaggtactgaagttctatagg
agcatgacactactcaacaccatggaccgaattctgtatgagtcccaacggcagggccgg
atctccttctacatgaccaactatggtgaggaggggacacatgtggggagtgccgccgcc
ctggaccgtacagacctggtgtttggccagtaccgggaggcaggtgtgctcatgtaccgc
gactaccctctggaactgttcatggcccagtgctatggcaacgtgaatgaccctggcaag
gggcgccagatgcccgttcactatggctgcaaggagcgccacttcgtcaccatctcctcc
cctctggccacacagatccctcaggcggtgggggcagcctatgctgccaagcgggccaat
gccaaccggattgtgatctgttactttggcgagggggcagccagtgaaggggatgcccat
gctggcttcaactttgctgccaccttggagtgtcctatcatcttcttctgccggaacaat
ggctatgccatctccacaccaacctccgagcagtaccgtggggacggcatcgcggctcgg
ggccctgggtatggcatcctgtcaatccgtgtggacggcaacgatgtgtttgcagtgtac
aatgccactaaggaggcccggcggcgggctgtggctgagaaccagcccttcctcattgag
gccatgacctacaggattgggcaccacagcaccagtgacgacagctcagcataccgctca
gtggacgaggtcaactattgggacaagcaggaccaccccatctcgaggctgaggcagtac
ctgctgaaccagggctgctgggatgaggagcaggagaaggcctggcggaagcagtcacgg
aagaaggtgatggaggcctttgaacaggctgagcggaagctaaagcccaacccgaacctg
ctcttctctgacgtgtatcaggagatgccagcccagctccgcaggcagcaggagtcactg
gtacgacatctgcagacctatggggagcactaccccctggaccactttgacaagtga
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