Cricetulus griseus (Chinese hamster): 100774580
Help
Entry
100774580 CDS
T02813
Symbol
Egfr
Name
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge01521
EGFR tyrosine kinase inhibitor resistance
cge01522
Endocrine resistance
cge03272
Virion - Hepatitis viruses
cge04010
MAPK signaling pathway
cge04012
ErbB signaling pathway
cge04014
Ras signaling pathway
cge04015
Rap1 signaling pathway
cge04020
Calcium signaling pathway
cge04066
HIF-1 signaling pathway
cge04068
FoxO signaling pathway
cge04072
Phospholipase D signaling pathway
cge04144
Endocytosis
cge04151
PI3K-Akt signaling pathway
cge04510
Focal adhesion
cge04520
Adherens junction
cge04540
Gap junction
cge04630
JAK-STAT signaling pathway
cge04810
Regulation of actin cytoskeleton
cge04912
GnRH signaling pathway
cge04915
Estrogen signaling pathway
cge04921
Oxytocin signaling pathway
cge04926
Relaxin signaling pathway
cge04928
Parathyroid hormone synthesis, secretion and action
cge04934
Cushing syndrome
cge05160
Hepatitis C
cge05163
Human cytomegalovirus infection
cge05165
Human papillomavirus infection
cge05171
Coronavirus disease - COVID-19
cge05200
Pathways in cancer
cge05205
Proteoglycans in cancer
cge05206
MicroRNAs in cancer
cge05207
Chemical carcinogenesis - receptor activation
cge05208
Chemical carcinogenesis - reactive oxygen species
cge05210
Colorectal cancer
cge05212
Pancreatic cancer
cge05213
Endometrial cancer
cge05214
Glioma
cge05215
Prostate cancer
cge05218
Melanoma
cge05219
Bladder cancer
cge05223
Non-small cell lung cancer
cge05224
Breast cancer
cge05225
Hepatocellular carcinoma
cge05226
Gastric cancer
cge05230
Central carbon metabolism in cancer
cge05231
Choline metabolism in cancer
cge05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03272 Virion - Hepatitis viruses
100774580 (Egfr)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100774580 (Egfr)
04012 ErbB signaling pathway
100774580 (Egfr)
04014 Ras signaling pathway
100774580 (Egfr)
04015 Rap1 signaling pathway
100774580 (Egfr)
04630 JAK-STAT signaling pathway
100774580 (Egfr)
04066 HIF-1 signaling pathway
100774580 (Egfr)
04068 FoxO signaling pathway
100774580 (Egfr)
04020 Calcium signaling pathway
100774580 (Egfr)
04072 Phospholipase D signaling pathway
100774580 (Egfr)
04151 PI3K-Akt signaling pathway
100774580 (Egfr)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100774580 (Egfr)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100774580 (Egfr)
04520 Adherens junction
100774580 (Egfr)
04540 Gap junction
100774580 (Egfr)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100774580 (Egfr)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
100774580 (Egfr)
04915 Estrogen signaling pathway
100774580 (Egfr)
04921 Oxytocin signaling pathway
100774580 (Egfr)
04926 Relaxin signaling pathway
100774580 (Egfr)
04928 Parathyroid hormone synthesis, secretion and action
100774580 (Egfr)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100774580 (Egfr)
05206 MicroRNAs in cancer
100774580 (Egfr)
05205 Proteoglycans in cancer
100774580 (Egfr)
05207 Chemical carcinogenesis - receptor activation
100774580 (Egfr)
05208 Chemical carcinogenesis - reactive oxygen species
100774580 (Egfr)
05230 Central carbon metabolism in cancer
100774580 (Egfr)
05231 Choline metabolism in cancer
100774580 (Egfr)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100774580 (Egfr)
09162 Cancer: specific types
05210 Colorectal cancer
100774580 (Egfr)
05212 Pancreatic cancer
100774580 (Egfr)
05225 Hepatocellular carcinoma
100774580 (Egfr)
05226 Gastric cancer
100774580 (Egfr)
05214 Glioma
100774580 (Egfr)
05218 Melanoma
100774580 (Egfr)
05219 Bladder cancer
100774580 (Egfr)
05215 Prostate cancer
100774580 (Egfr)
05213 Endometrial cancer
100774580 (Egfr)
05224 Breast cancer
100774580 (Egfr)
05223 Non-small cell lung cancer
100774580 (Egfr)
09172 Infectious disease: viral
05160 Hepatitis C
100774580 (Egfr)
05171 Coronavirus disease - COVID-19
100774580 (Egfr)
05163 Human cytomegalovirus infection
100774580 (Egfr)
05165 Human papillomavirus infection
100774580 (Egfr)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100774580 (Egfr)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100774580 (Egfr)
01522 Endocrine resistance
100774580 (Egfr)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cge01001
]
100774580 (Egfr)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
cge04147
]
100774580 (Egfr)
Enzymes [BR:
cge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100774580 (Egfr)
Protein kinases [BR:
cge01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100774580 (Egfr)
Exosome [BR:
cge04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
100774580 (Egfr)
Exosomal proteins of pancreatic cancer cells
100774580 (Egfr)
Exosomal proteins of bladder cancer cells
100774580 (Egfr)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100774580
NCBI-ProteinID:
XP_035309194
UniProt:
A0A9J7KCK1
LinkDB
All DBs
Position
1
Genome browser
AA seq
1154 aa
AA seq
DB search
MFNNCEVVLGNLEITYVQRGYDLSFLKTIQEVAGYVLIALNTVEKIPLENLQIIRGNTLY
ENTYALAVLSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMETIQWKDIVHNDFL
SNMSMDLQNQPSSCQKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSRRCRGRSPSDCCH
NQCAAGCTGPRESDCLVCHKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVK
KCPRNYVVTDHGSCVRACGPDYYEVEEDGVRKCKKCDGPCRKVCNGIGIGEFKDTLSINA
TNIKHFKYCTSISGDLHILPVAFKGDSFTRTPPLDPRELDILKTVKEITGFLLIQAWPEN
WTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVVISGNRNLCYAN
TINWKKLFGTSNQKTKIMNNRAPNDCKATGHVCNSLCSPEGCWGPSPRDCVSCQNVSRGR
ECVEKCNVLEGEPREFVENSECIQCHPECLPQDMNITCTGRGPDNCIKCAHYIDGPHCVK
TCPAGIMGENNTLVWKYADANNVCHLCHPNCTYGCIGPGLQGCGSRPRIPSIATGIVGGL
LFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKK
IKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHV
CRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLV
HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQ
SDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMID
ADSRPKFRELIVEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDAD
EYLIPQQGFFNSPSTSRTPLLSSLSATSNNSTVACINRNGSCRIKEDGFLQRYSSDPTGA
LMEDSMDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLHPAAGRDLHYQNPHSNAVSNP
EYLNTAQPTCVSSAFDSPALWAPKGSHHMNLDNPDYQQDFFPQEAKPNGIYKGPTAENAE
YLRVAPTSSEFIGA
NT seq
3465 nt
NT seq
+upstream
nt +downstream
nt
atgttcaacaactgtgaagtggtccttgggaacttggaaattacctacgtgcaaaggggt
tatgacctttccttcttaaagaccatccaggaggttgctggctatgtgctcattgccctc
aacactgtggagaagatccctctggagaacctgcagatcatcagggggaacactctgtat
gaaaacacctatgccttagctgtcctgtccaactatgggacaaacagaaccgggcttaga
gaactgcccatgcggaacctacaggaaatcctgattggtgctgtgcgatttagcaacaac
cccatcctctgcaacatggagactatccagtggaaggacatcgtccacaatgactttctg
agcaacatgtcaatggacttacagaaccaaccaagcagctgccaaaaatgcgatccgagc
tgtccgaacggaagttgctggggaggaggagaagagaactgccagaaattgaccaaaatc
atctgtgcccagcaatgttcccggcgttgccgtggcaggtcccccagtgactgctgccac
aaccagtgtgccgctggttgtacaggaccccgagagagtgactgtctggtctgtcataag
ttccgggatgaagccacatgcaaagacacctgcccaccactgatgctgtacaaccccacc
acatatcagatggatgtcaaccctgagggaaagtacagctttggcgccacctgtgtgaag
aaatgcccacgaaactatgtggtgacagatcatggctcctgtgtccgggcctgtggtcca
gactactacgaagtggaagaagatggtgtccgaaagtgtaaaaagtgtgatgggccctgt
cgcaaagtttgtaatggcataggcattggtgaatttaaagacacactctccataaatgct
acaaacatcaaacacttcaaatactgcacttccatcagtggggaccttcacatcctgcca
gtggcctttaaaggggatagcttcacacgtactcctcctctagaccctcgggaactagat
attctaaaaaccgtaaaggaaataacagggtttttgctgattcaagcttggcctgaaaac
tggactgacctccatgcttttgagaacctagaaataatacgtggcagaacaaagcaacat
ggtcaattttctcttgcggtcgttggcctaaacataacatcattgggattgcgttccctc
aaggaaataagtgatggagatgtggtcatttctggaaaccgaaatttgtgctacgcaaat
acaataaactggaaaaaactctttgggacttctaatcagaaaaccaaaatcatgaacaac
agagccccgaatgactgcaaggccacaggccatgtgtgtaattctctatgctccccggaa
ggctgctggggcccttcgcccagggactgtgtctcctgccagaatgtcagcagaggcaga
gagtgtgtggagaagtgtaacgtcctggagggggagccaagggagtttgtggagaattcc
gagtgcatccagtgccatccagaatgtctgccccaggacatgaacatcacctgcacaggc
cggggaccagacaactgcatcaaatgtgcccactacattgacggcccacactgtgtcaag
acttgcccagctggaatcatgggggagaacaacaccctggtttggaagtatgcagatgcc
aataatgtctgccacctctgccatccaaactgtacctacggatgtattgggccaggtctt
caaggatgtggatcaaggcctaggatcccttccattgccactgggatcgtgggtggtctc
ctcttcatagtggtggtggccctggggattggcctgttcatgcgaaggcgccacattgtc
cgaaaacgtacactccgccgcctgcttcaggagagagagcttgtggaacctctcacaccc
agcggagaagctcccaaccaagccctcttgaggatcttaaaggaaacagaattcaaaaag
atcaaagttttgggttccggagcatttggcacagtgtataagggtctctggattccagaa
ggggagaaagtgaaaattcctgtagccatcaaggagttaagagaagccacatctccaaaa
gccaacaaggaaatccttgatgaagcctacgtgatggccagtgtggacaaccctcatgta
tgccgcctcctgggcatctgcctgacctccactgtccagctcatcacacagctgatgccc
tatggctgcctcctggactatgtacgagagcacaaggacaacattggctcccagtaccta
ctcaactggtgtgtgcagattgcaaagggcatgaactatctggaagatcggcgcttggtg
catcgtgacttggcagccaggaatgtactggtgaagacaccacagcatgtcaagatcaca
gactttgggctggccaaactgcttggtgctgaggagaaagaataccatgcagagggaggc
aaagtgcctatcaagtggatggctttggaatcaattttacaccggatttatacacaccaa
agtgatgtctggagctatggagtcactgtgtgggaactgatgacctttgggtccaagcct
tatgatggaatccctgccagtgagatctcttccatcctagaaaaaggagaacgccttcca
cagccacctatctgcaccatcgatgtctacatgatcatggtcaagtgctggatgatagat
gcagatagccgcccaaagttccgagagttgattgttgaattctccaaaatggcccgggac
ccccagcgttaccttgttatccagggagatgaaagaatgcatttgccgagccctacagac
tccaatttttaccgagccctgatggatgaagaggacatggaagacgtagttgatgctgac
gaatacctcatcccacagcaaggcttcttcaacagcccgtccacatctcggactcctctc
ttgagttctctgagtgcaaccagcaacaattccactgtggcttgcatcaatagaaatggg
agctgtcgtatcaaggaagatggcttcttgcagcggtacagctccgaccccactggtgcc
ttaatggaggacagtatggatgacacgtttctccctgtgcctgaatatataaaccagtct
gtccccaaaaggccagcaggctctgtgcagaaccctgtttatcacaatcagcccctgcat
ccagctgctggcagagatctgcattatcaaaatccccatagcaacgcagtgagcaaccct
gagtatctcaacactgcccagcctacctgtgtcagcagtgcgtttgacagccctgccctc
tgggctccaaaaggcagccaccatatgaacctggacaaccctgattaccagcaggacttc
tttccccaggaagccaagccaaatggcatctataagggtcccacagctgaaaatgcagaa
tacctaagggtagcacctacaagcagtgagtttattggagcctga
DBGET
integrated database retrieval system
