Carassius gibelio (silver crucian carp): 127963922 Help Entry 127963922         CDS       T08819                                  Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism cgib  Carassius gibelio (silver crucian carp) Pathway cgib04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cgib00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     127963922  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cgib01001]     127963922   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cgib04131]     127963922 Enzymes [BR:cgib01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      127963922 Protein kinases [BR:cgib01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    127963922 Membrane trafficking [BR:cgib04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     127963922 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase PK_Tyr_Ser-Thr Ig_5 Ig_4 Izumo-Ig SOS1_NGEF_PH RhoGEF Ig_CD22 Ig_6 PH Kdo C2-set_2 IQ fn3 RHG20_PH IQ_SEC7_PH Motif Other DBs NCBI-GeneID:  127963922 NCBI-ProteinID:  XP_052419981 LinkDB All DBs Position B8:complement(10277294..10320855) Genome browser AA seq 6729 aa AA seqDB search MALNRIQLVKGLEDVTLCEKEACTFEVVLSHAYIQGQWSRDGVPLKSRPVCRIATQGKKH TLTLTRVTVADMGVISFKAEGIESSAMLTVKARNIKIVKALQNVSVTERESVTFICEVNW EDVDGKWYKDDSRLRAGDNVKIKCEGKTHSLTYKSVKPEDAGEIRFTAERVSSTATLGVK ELPVHIVKPLRVKIAMYKHRALLECQVSRVNAVVKWYRRNHEIVPNRKYQTISEGVYRQL IIDDVGSSDEDTFTCDAVDDRTSCQLFVEEQAISILKGLSSVEVMEPKEARFKVETSIKL ERAPKWTLNGQILCPCPEIRIERQGTSNRLIFTQTDSSMCGTVQFTSGKSKSEAQLTVTE RPLIVKQPISDVEVKENRSVTLSCEFCPSPRVVRWFKGRTPLFASNKYTMKREKNRVEMT IMGVKAADSGEYRCLAGGSEARGRVSVEVKRLKIIRHLEQVEVEEDGTAVFSCELNHESP SVQWLLNDRVLYTNYINKIQNSGKAYSLILKRLAPQESRVTFKTFDISESAFLRVREKPA VFLRSLEDVAGEERGEILLQCDVSKPSVTPVWRKDGEILTASEKYEILHVGKSLTLIIHK LRKDDGGEYSCDIGCSQTKAKVIVRDLRITIVKRIRTTAVLEGESCSFECVLSHDIIDEA SWILNGQLIVSNGRIIVSNKGCKYTMSIQEVTISDAGEVVFTIKEFSCRTMLFVKEKPVR VFRDMLNVKATPGEDPELSCEITKPDATIKWLKNGRLIRVSPKYEITQNNYLVKLIIHNA AIMDSGEYCCEADGIATRARLEVRDLQHTFAKELKDMRAEEKGMVTMECETRRPAATVTW LKGLMVLSSGQKYMMKKKDVVLTLTIFNLEKSDSAVYTCDVGTMQSRALLTIQGQKVVIV DELEDKECLEGDTITFKCRICPSDYTDVKWYLDETLLYTNDLNEIKMIPGGYHTLTFKQL ARKDTGTISFEAGDKRSYASLLVRERRPTITKALEDTEAIEGGSLVLLCKTSKPCHIVWY KDGCLIWNSSKFLVSRSGNEARLAIRDVKDSDAGLYECDAGSVSTKATVSVKVIPAEFTK ALQNQEVKEGESVTLMCEYSIPGVQFVWRKGPETLKSSEKYHMRQRKSCISLTIHNLKPE DSGNYTCICRDQRTMATLTVNEVPISFIKELKNQEIDEGKNVTLRCELSKAGIPVEWLKG EQTLLPGEKYQMRHIVTILELVIRNPVHEDSGTYICVCDDQRTKAIVKIRTQPVTFKQKL RNQMVEEGNSIILHCEISKPDISVQWRKGSSLLRSGEKYKIRQRGCMLELKIFNLTQDDS GVYSCTSETAETSANITVSAQPVTFKDKLKNLEAVEGNMVTLHCELSKTGVPVEWWNGEE LLQPGEKYKMRERGTSVELIICEAMPEDSGVYRCVCGDQKTKATVKIVGAPASFKQNLKN QEALEGKSVTLHCELSKAGVPVEWWRGDKPLLPGPHYQMRLDGKTAELKITNVFPDDAGI YSCVTGSQRTTAEVKVKPLPITFKRELQNQISTEGKSAVFTCELSKPGAPVEWRKGRVML KSGAKYQMTLEGRLTKLLINNLVEGDAGNYTCKTKDSQSTAELTVQGLPAIFKTNLKNQE TQEGNSVNLHCELSKAGVRVEWWKGEELLKTGEKYQLRQKEATVELLIRKAQPEDSGVYR CICGDYKTEATIKVNALPITFKQELKDQEGEEGNNITLRCELSKASADVKWLKGDEVLKH GEKYQLRQIATKMELVIRKAIPEDSGVYFCVCPDQTSKATVKINALPITFKQNLRKQEVV EGNTVAFRCELSKPGATVKWWRGEEVLQGGEKYQMRNEGRIAELLIKNVNSEDVDFYSCT TGKEKTTAEVKVRAVPVTFKRELQNELTKEGGQAVFSCELSKPGAQVDWRKGRIILKPDD KYEMKQEGTFTKLVIRNVEASDAGNYSCKTKDSESTAELTVKVPPITFKVKLKNQEVEEE NKLVLHCELSKAGCPVEWRKGEELLRSGYKYQIQEHDVTRELIITKAMPEDSGVYSCICG EQKTKATIRVFATPVTFKQNLKNQEAPEGGVVILHCELSKAGVPVTWLKGDEELCNGNRY KIKQEGLVAELHIKNVLPKDVGEYSCIVGDQKTTAEVNVRAAASVFFEKELESQEAMEGD SVLFRCLLSSDNAPVTWRKDTNQITQGGRYTLHRKGSTQELEIRKLRMQDAGMYSCSVRG KNTSATLRVIERVRIVKGLRDLTVTAGESAHFVCELSHENILDGVWWLGSNELQENEMNQ MSVCGREHHLVLTMTTTEESGVVSFVVGNEKTSACLRVNSKPTVLIEERLKDMTIFEGDS ATLSCVTSDTCTPVTWKRNNVTLLSGEKYEPLKHGKRNVLLIHKVRKEDAGIYMCDTGDM QSSATLTVKERPLFFCRELQNQEAEEGETTFLCCELSQPGVAVEWKKGAILLRPGNKYEI KQDGCEQQLQINDLTSQDSGAYRCCADGIETRASITVKERPLFFHEELQNQEAEEGESAF LCCELSKPGVAVQWKKGAMLLKNGHKYEMTQDGNEVQLQIHDLTSQDSGIYRCCAGNIET RANIIVKEQPLFFCEELHNQEAEEGETAFLCCELSKPGVEVQWKKGAIRLRPGDKYEMKQ DGCKVQLQIHGLTRQDSGTYKCCSGSLVTTASIVVKEHPLYFIKMLECQEAEEGETAFLC CELSKPGAAVQWKKGSVLLKPGRKYEIKQNGSELQLQIHELTSQDSCVYTCCVGSLVTSA SLEVKEQPLFFCEELQKQEVEEGETAILSCELSKPGVEVQWRKGTVLLRPGNKYEMKQDG CKLQLLIYELNSQDSGVYKCCAGSLVTTASIDVKESPVVFQEELQSLEAEEGGTATLTCE LSKPGVAVQWKKATVLLKPGNKYEMKQDGCLQQLQIYDLKHEDSGLYKCCAGSLVTTASL VVKEHRLFFSKELQNQEAEEGRTAILCCELSKPGVSVQWKKGTVLLKSSNKYKIKEDGCQ LQLQIHELTAQDSGAYKCCAGSLVTTGSLVITEKPLYFSEELQNQKAEEGKTVTLHCELS KPGVSVQWKKGTFLLKASKKYDIKQDGRELQLQINELTAQDSGTYKCCVGNLVTTASLVV KEQPLFFSEELQNQEAEEGNTITLHCELSKPGVSVQWKKGTVLLKPSKKYDIKQDGRELQ LQIHEPTTQDSGVYKCCVGSLVTTASLVVKEHSLFFSEELQYQEAEEGKTAILCCELSKS GISVQWKKGTVLLKPSKKYEIKQNGRQLQLQIHDLTVQDSGDYKCCVGNLVTTASFVVKE KPLFFSNELQNQEAEEGKTAILCCELSKSGVSVHWKKGTVLLKPSKKYEIKQDGRQLQLC IHELTTQDSGAYKCCVGSLLTTCSVTVKEQPIFFCKNLQSLEAEEGETVTLICEISKPGV AVQWKKGTVLLKAGNKYEMTQNGCVLQLQIRDLKSDDSGSYKCCTGSVVTTASLVVNEHP LFFSKELQNQEAEEGKTVTLYCELSKPGVSVQWKRGAVILKPCKKYEIKQDGYQLQLQIH EVTAQDSGVYKCCAGSLATNGSIKVTEQPLFFCKNLQNLESEEGETAFLTCELSKPGVAV QWKKGSVLLKPGNKYEMKQNGSELHLQIHDLKCQDSGVYKCCAAKMETKASVVVKESPPK IKDIPQAPPRIKGKNIMEETHSGLDHKKQAAVIEESDISIFDPSEVHFQDLCEKPTDDQE VKPKSLVRQKGEDVSSSMVISESTCTMGEPEISSLAINVHKEQRKKELDTNSKWVTKISV DQHNEEISGQVQKKTPSIDPSEQSKEPPREVPLPPPRSKGKATHPDDSFQDQHSVKEPTL DKRGKKQDVVVEATVETTKASKHVDLTVSLPKENASQLHVETKRQPYVLEAKIQDMDIKQ CVDTTLKISEHGLNTPFFEEITAKHIESSHLEQPCHLEGNNQYIKQKSTVNKEPKQEQIV SKETELEEFAPQTNTNKEPKQKSLDKNVAHENQNVQSEERSEIKKVKSIDEHHGQITKNI TEQPSIAITSQKPKKPILCAQRDSSMPVRDVQKELQAGELNLPHIDSGELKHVQQVVDEH HGKVPKHVTEKPKQIAITSQKFKEEIITAVKTTAIKDVQKYSEEGELNLPHTDSEDVKNV KQALDEDKVKVRKPVTGKATNIAIASKFKEETIPAEKATTMSIKDVQRVSQEVEPNVQHI DIGDEKNVKQVIDEHNVKLPKHVKEKAPSITRPQIIPPKKAVTISFREVQKASQEVEPNL PHMDDKDQKNLKEVVIEGQKEDVSRGLSSQPEEMMPEQITSVDTDKQKSLKAEQGGPGID IDSEDEPEMLEAAIKIQAAFKGYKTRKDMRPIFKEVFKNQNINLGGTAFLECVVEGKISN VRWLKDGVTLKPGERHKITHNAYGRCLLEISSFTNKDAGIYTCEVANKFGAVSYNGNVMV GKPQKPSQTIQTAQTPSTEMVTEKEVLPTINMEEESLRLVYDLPADDTYSKIQEKRRSLI SVSSISCYSDYDTAPDVETDYQSRGKEAKTAKTEASTTQTSKEENIITVQSPKNTDQLKV KGGNSQSQTPSPKRIHSYKSSANAESFSESDGDDDRGETFDIYVAKSDCQPLGGNQEAFV LKEGQFVEVLDSAHPVRWLVRTKPTKLTPSRQGWISPAYLEKKTREIFSLAHEAETKESP EKGKTVFTKDEHSLIQSRLIKGLLDGENNFVRELNFFVEHHLQYLETSTQVPLTILSQKE YIFRNIRDIASFHECCILPKLEMCFSDDDVAQCFVSYALDFEMYLQFITGLPQAEACISE KNTQHFFKQYANTELAHLDTQVFSVSTYLQRPMERIQTYKNVLKELIRNKAKSGQNCCLL EDAFAIVSSLPWRAENLHHLSMIENYPAPLKGLGEPIRQGYFTVWEEIPEVKISQRGHHR HVFLFKDCIVFCKPKRELGTYTEAYIFKNKMKLSDIDVKDTVEGDDRSFGLWHEHRGMVR KIILQARSILLRLSWLKDLRDLQQRSKQPTWTAPCFEQHLSDYPAKLGQTVKLVCKVTGT PKPVIKWYKDGHAVKEDEHHITSEGQLGACYLVLTGVIEADSGQYMCYATNHAGNASTLA NIMIDVPPSFTTRLQNSVLVKGQDAQFRCSTQSAPLPSIRWFKDGIQLEDNRKHQIQSDV QTGILTLTIKKAEEADLGQYQCELQNEVGSAKCKAELCPPAPLPVSVRTQKQSQTTPTSD PQSDGWSSSFVKNLFHILFQTGNPEPSAAGVEDPQTLKEQDDMERQVQVAQEEGPVEPEE HFYSDTEEEFLTEPPAVQVAIEDLTVRPGQPATFSAIITGQPSPDIQWFKDDKEILSNDH TEICQSNARCSLTLLNTQIEDCGTYSCIAINSAGQASCLAKLSVDTGPDEIEEQREVEFG KRRKLHSVYDVHEEIGRGTFGVVKKVTHKANGECFAAKFLPLRSRTRTRAFQERDLLSRL AHRRLACLLDFFTTRRTLVLVVELCSTQGLLDHLFLKGSVSEREVQLYIQQVLEGIGYMH SMNILHLDIKTDNILMVSPAREDIKICDFGFCQEIDNSRHQYSKFGTPEFVAPEIVHQEP VTVTTDIWSLGVVTYLCLTSHCPFFGENDRSTLMKVAEGVLYWDTPEITSRSVEAQDFLH RVLQPDPEMRPSASECLSHEWFQGYYEDEEPEHINTKNLKSFISRRKWQRSLTCLGSVLT LRPIPELLEAPLRDVSITATRETQEPSSTSLSSGSSSEFDEADSWDFFQQVSQEDEDDLE EEEEYDPYTPVSKMPTVLKLDEEDVLIGEDRFHSGPLVIPMTAPSTEPVSLERTDSSPYL HLSEVKDEGLDPIPRRTLIKSTFYCSSEQLSPMSARHMTLRDKIQAKKQERGRKPLRASL SGRLNEPLIEYVEDSPDLEANRNQRRGSMHSSMLKSSSFDSGVSAAHPSIHTQRRSRSLD VYTQRSPASIEPTVQGEEDEHDVEESQKPDVTDEEEEKTEEVQVRRKLCRRSAFLSKKGP LIVRKVRAQVCEPEEGHQPALQSSCEEDDQLQVTETDTRHLGDEESVDGSQLSLACSLDH GSEASSRIGSHEELSHRHHHEESLIAGSSGKTSPCSLLQDSEDEDMERVLRSLRQDLPKA PPRRRSISSSSGLNEMRNRSDVLLRRSSSAVPVQASVEGRESIELLQRHASAPALQAKPP SGKSSKAGFMKIFRKHSWASHSSPQLEGSEKKQTEGASSQPKSPLLTLRKKMRASASSIT KLFTRQPSKEDEEKKKGGPIVKNSSPVIPEKMTTVMTTSSESPQKKSKLFSLKVPIFKKT KESPVKPSRPDVIQLAGGGALVFWKPVPSKELVTYCIQYSVNGVEWRMLAENVTDSCFTV NALPRGPGYMFRVSHNTKRGLAPFSDPSPPAFMATPYEDSHNPLIKMESIGSKVTVPGGL GTEKSYSFLSEINRGRFSVVMQCEDSRSSQMLAAKITLYRPEQRQLVLREYQLLRRLNHP RIVQLQSAILTPTFLVLIEELCSGRELLYNLAERTLYSETQVTNLLEQILSAVDYLHSRR IVHLDLKSDNMLVTGRNVVKIVDLGSAQPFTPGQALNIEHIKEITDNKGYIVLPKAPEIL EGQGVGPETDIWAVGVLAFIMLSADSPFHADINWERDRNIKKGKIQFNRCYPGLSEGAIN FMKNTLSNKAWARHTAAECLQNPWIQGDRPPSKHTDSVVCFSTDKLQAYLREREVKRDHI RTKINLPFP NT seq 20190 nt NT seq  +upstreamnt  +downstreamnt atggcattgaatagaattcagttggtaaaagggctagaagatgtgacgctgtgtgagaaa gaagcctgtacatttgaggtggtcctcagtcatgcgtacatccagggtcaatggagcagg gatggcgtaccacttaaatccaggcctgtttgtcgaattgccacgcagggcaaaaaacac acactcacactcacgcgtgtcacggttgctgacatgggtgtcatcagtttcaaggctgaa gggattgaaagctctgcaatgctgacagtcaaagccaggaatataaagattgtgaaggct cttcagaatgtcagtgtgactgagagggagagcgtgacatttatctgtgaggtcaactgg gaagatgtggatgggaagtggtacaaggatgacagccggttgagagctggggacaatgtt aaaataaaatgtgaaggtaaaacacactccttaacctacaaatcagtcaaaccagaagat gctggtgagatcagattcactgctgagagggtctcttcaacagcaacactgggagtcaaa gagcttccagttcatattgtgaagcccctgagagtgaagatcgccatgtacaaacatcgt gccttgctggagtgccaggtctctcgtgtcaatgctgtggttaaatggtacagaagaaat catgaaattgtgccaaataggaagtaccaaactatcagtgaaggcgtgtaccgacagctt atcatagatgatgtgggatcttcagatgaagacacttttacctgtgatgctgtcgatgac aggacttcctgccagctgtttgtagaggagcaggccatcagcattttgaaaggactcagt tctgtggaggtcatggagcctaaagaggctcgttttaaagtggaaacaagtattaagtta gagagggcacccaaatggaccctgaatgggcagatactatgtccctgtccagaaatccgg attgagaggcaaggaacatcgaacagactcattttcactcagaccgacagtagtatgtgt ggcactgtgcagttcacctcggggaagagcaagtcagaagctcaactcacagttacagag cgccctttgattgtcaaacagcccatttctgatgtggaggtgaaggagaacaggtcagtt actctcagctgtgagttctgtccatcccccagagtggtgcgctggttcaagggtagaacc ccactgtttgcttccaataagtacacaatgaagcgggaaaagaaccgggttgagatgacc atcatgggtgtgaaagcagcagattcaggagagtatcgctgtctggctggtggctcagag gcaagaggaagagtcagtgtggaagtgaaaaggttgaagatcataagacacttagagcaa gtagaggtcgaggaggatggaactgcagtgttcagctgtgaactgaatcatgagtcaccc agtgtccagtggctgctcaatgaccgagtcctatacaccaactacatcaacaaaatccag aattctggaaaagcatacagtctgattttaaaacgactagctcctcaagagagccgtgta acattcaaaacatttgatatcagcgagtctgcgttcctcagggtcagagagaagccagca gtgtttctcaggtcattggaggatgtagcaggtgaggaacgtggtgaaatccttttgcag tgtgacgtttccaaaccatcagtgacacctgtctggagaaaagatggtgaaattctgacc gccagtgagaagtatgagattctccatgtgggaaagtcattgactcttataattcacaag ctgagaaaggacgatggaggagagtacagctgtgatattggctgcagccaaactaaagcg aaagtcatagttcgtgacctgcgcattaccattgtcaaacgcatacggacaacagctgtg ctggaaggggaaagctgcagctttgagtgtgtcctgtcccatgatatcattgatgaagca tcgtggattttgaatggccagctgattgtgagcaatggaagaatcatagtctctaacaaa gggtgcaaatacacaatgagcattcaggaagttacaatatctgatgctggcgaagtggtc tttaccattaaagagttcagctgcaggactatgctgtttgtgaaagagaaacctgtgaga gtttttagggatatgttgaatgttaaagcaacacctggtgaagatccagagctcagctgt gagatcacgaaacctgatgcaacaattaaatggctgaaaaatgggcggctaattagagtc agcccaaaatatgaaattacccaaaataattatctagtgaagctcatcatccataatgca gctataatggactcaggagagtactgctgtgaggctgatgggattgctacaagggcgaga ttagaggtcagagacttgcaacatacatttgcaaaggaactgaaggatatgcgtgcagag gagaagggtatggtgaccatggagtgtgaaaccagaaggcctgcagctactgtgacctgg ttaaaaggtctaatggtcctcagctcgggacagaagtacatgatgaagaagaaggatgtt gtcctcactctgaccatcttcaatctggagaaaagtgatagtgctgtctacacctgtgat gttgggacaatgcagagcagggctttacttacaattcaaggtcaaaaagtggtcattgtg gatgaactcgaagataaagaatgtctagaaggagataccatcacctttaagtgtcgaatc tgcccaagtgactacactgatgtcaaatggtacctggatgagaccttactctacactaat gatcttaatgagatcaagatgatacctggtggataccacactcttaccttcaaacagctt gcacgtaaagacaccggcaccatctccttcgaggctggggacaaaagatcatatgcatca ctattagttagagagagacgccccacaataactaaagcattggaagatacagaagcaatt gaaggaggaagtttggtgctgttgtgcaagacctcaaagccatgtcatattgtttggtac aaagatggctgtttaatctggaattcctccaagttcttagtgagtcgatctggaaatgag gccaggctggccatccgtgatgtgaaagacagtgacgcagggttgtacgagtgcgatgca ggttctgtcagcacaaaagccacagtgtctgttaaagttattcctgctgagtttacaaaa gctcttcagaaccaagaagtcaaagagggagagagtgtaacgctgatgtgcgaatactct atacccggggtccagtttgtgtggcgcaaaggacccgagacgctaaaatctagtgagaag taccacatgaggcagaggaaatcttgcatttctcttacaatacacaatctgaagccagaa gattcagggaattacacatgcatttgcagagaccaaagaactatggctactcttacagtc aacgaggttcctatatcatttattaaagagctcaagaaccaagagatagatgaaggtaaa aatgtgacattacgctgtgagctttctaaagctggaatcccggtggaatggttgaaaggt gaacaaactctcttgcctggggagaagtatcagatgaggcacatagtcaccatactagag ctggtaatcagaaatccagttcatgaggacagtggaacatacatctgtgtgtgtgatgat caaaggaccaaagccattgttaaaatacgaactcaacctgtcacgttcaaacagaagtta agaaatcaaatggttgaagagggaaacagtataatcctacactgcgagatatccaaacca gacatctctgtgcagtggagaaaaggaagcagccttctcaggtctggggaaaagtacaaa atcagacagagaggctgcatgctagagctgaagatttttaatttgacgcaagatgatagc ggagtctatagctgtacgagtgaaactgctgagacatcagccaacatcacagttagcgct caacctgttacttttaaagataaactgaaaaacctggaagccgtggaagggaacatggta acattgcactgcgagctttctaaaacaggtgtcccagtagaatggtggaatggagaggaa ctgctccagcctggagagaagtataaaatgagagaacgaggcacatcagttgagctgatc atctgtgaagccatgcctgaagacagtggagtttacagatgtgtctgtggagaccaaaag accaaagctacagttaaaattgttggtgctcctgctagttttaagcaaaaccttaagaac caagaagctctggaaggcaaatctgtaacccttcactgtgagctttccaaagctggagta cctgtggaatggtggagaggagataaaccgctccttccagggccacattaccagatgagg ctggatggaaagactgcagagttgaaaataacaaatgttttccctgatgatgctgggata tacagttgtgtgactggaagccaaaggaccacagctgaagtgaaagtcaaaccccttcca attactttcaagcgagagcttcagaatcagatatctacagagggtaagagtgcagtattt acctgtgaactttcaaagcctggtgctccagttgagtggaggaaaggtagagtgatgctg aaaagcggagccaaatatcagatgacgcttgaggggcgattaaccaaactgctgataaat aatctagttgagggtgatgcgggaaattacacctgcaaaaccaaagattctcaatcgaca gccgaattgacggttcaaggactccctgctatctttaaaacaaatttgaagaaccaagaa actcaggaggggaacagtgtcaatctgcactgtgaactttctaaggctggagttcgagta gagtggtggaaaggagaagaactgctcaagactggagaaaaatatcagttgagacagaaa gaagcaaccgtagagttgttaataaggaaggcacaaccagaagacagtggagtgtatcgc tgcatatgtggagattacaagacagaagccaccatcaaagttaatgctctccctatcact ttcaaacaagaacttaaggatcaagaaggtgaagaagggaacaacatcacattgcgctgt gaactctctaaggccagtgctgatgtgaagtggttgaagggagatgaagtcctaaagcat ggtgaaaaataccagttgagacagatagcaactaaaatggagctcgttatcagaaaagcc atacctgaagacagcggagtctacttttgtgtatgccctgatcagacatccaaagctaca gttaaaatcaatgctctcccgatcactttcaaacaaaacttgagaaaacaagaagtggtg gaaggaaacacagtagctttccgttgtgagctttccaaaccgggagctacggtgaaatgg tggaggggtgaagaggtgctgcagggtggagaaaagtaccagatgaggaatgaaggacgg attgctgaacttcttattaaaaatgtcaactctgaagatgtcgacttctacagctgcact acaggaaaggaaaaaacgacagcggaggtcaaagttagggctgtacctgtcactttcaaa cgagaacttcaaaatgaattaaccaaagaaggtgggcaagctgtttttagctgtgagctg tctaaacccggcgctcaagttgactggagaaaaggaagaattattctcaagcctgatgat aaatatgaaatgaagcaagagggcacattcaccaaactggtcatacgtaatgttgaagca agtgatgctgggaactattcatgtaaaaccaaggattctgagtcaactgctgagctaacc gttaaggttccaccaatcacttttaaagtcaagttgaaaaatcaggaagttgaagaagaa aataaacttgtgttgcactgtgagctctcaaaagctggatgtcctgttgaatggaggaag ggggaagagcttcttaggtcagggtataaatatcaaatccaagaacatgatgttacaagg gagctgatcatcacaaaggccatgcctgaagacagtggagtctacagctgcatttgtgga gagcagaagaccaaagccacgatccgagtattcgccacaccagtaacgttcaaacaaaac ctgaagaaccaagaagcccctgagggaggtgttgttattctgcattgtgagctgtccaaa gctggggtaccagtgacatggttaaaaggggatgaggagctctgcaatgggaatagatac aagataaagcaggagggattggttgccgaattacacattaaaaatgttcttcccaaggat gttggggaatacagctgcatcgttggagaccagaagactacagctgaagttaatgttagg gctgctgcctctgtgttctttgagaaagagcttgagagtcaagaagcaatggagggggac tctgtcctgtttcgttgtttgctctctagtgataatgccccagtgacctggagaaaagat acaaaccagatcacacagggagggcgatataccctccaccgtaaaggttcaacacaggag cttgaaatcaggaaactgagaatgcaggatgctggcatgtactcatgtagtgtcaggggc aagaacacctctgcgaccctcagagtgatagagcgtgtgaggattgtgaaaggactgcgt gacttgacagtaactgcaggtgagagcgcacactttgtgtgcgagctttcacatgagaac atccttgacggggtttggtggcttggttccaatgaacttcaggagaacgagatgaaccag 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atgcagtgtgaggatagtcgcagctctcagatgttagccgctaagataacactttacaga ccagagcagaggcagttggttttaagggaatatcaactgcttcgccgactgaaccaccct cgaatcgtccagctgcagtcggccatcctcacccccaccttcctggtgcttatagaggaa ctgtgctcaggacgagagctactttataaccttgcagaaaggactctttattcagaaaca caggtgactaacctactagagcagattctgagtgctgtggattacctgcacagcagacgc attgtacacctggacctaaagtcggacaacatgcttgtgacgggccggaatgtagtgaag attgtggatttgggctctgctcagcccttcactccaggacaggcactaaacattgaacac atcaaagaaataacagataataaaggttatattgtccttcctaaagctcctgaaatctta gaaggacaaggagttggacctgaaactgatatctgggctgttggtgttttggcttttata atgttgagtgcagacagtcccttccatgctgatataaattgggagagggatcgaaacatc aaaaaaggcaagatccagtttaatcgttgttacccaggtctctcagagggagccatcaac tttatgaagaacaccctgagcaacaaagcctgggcaagacatacagctgcagagtgcctc caaaacccctggatacaaggagaccgtccaccttccaaacacactgactctgtggtctgc ttctcaacagacaagctgcaggcctatctcagggaacgagaggtcaagcgagaccacatc cgcaccaaaattaatctgccctttccataa

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