Carassius gibelio (silver crucian carp): 127984290 Help Entry 127984290         CDS       T08819                                  Name (RefSeq) nesprin-1-like   KO K19326   nesprin-1 Organism cgib  Carassius gibelio (silver crucian carp) Pathway cgib04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cgib00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     127984290  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cgib03036]     127984290 Chromosome and associated proteins [BR:cgib03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     127984290 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 KASH Spectrin_Anc-1 Motif Other DBs NCBI-GeneID:  127984290 NCBI-ProteinID:  XP_052442830 LinkDB All DBs Position B20:complement(13166729..13296629) Genome browser AA seq 6577 aa AA seqDB search MDADISLYTRSLELWNDINKMANDIECWSAISVGELSEGAASLLSAHDMEGHLSEFKLEL DNKEDELKNLQTKMTQLQELMKTQHIHTELQVMAADLRKQISHAAEVYEQTKGMYKDFKS QRQQLQDLISQISEQLKTSEDSLSEFSSSADPENFVKIKEVERSQKQLEVSLDVASESLR ALCRTYPTQHLALLGDAVSHLVKWNEEVTQRRSQILGSLQDALLQRFNEKAHAFHCWLSE LRAGIEDCFEQTGDAVAISAKQQKLKTAVEEVMEGEERLARVCEDGERLLLHLSKCGTGS IQEQLDSCQYALDSFVMDCRQRIRALEESANLLNGYETRVVEMSDWLKQLEVRLKTDAPL RGESQSAAPDCSGELRRVEEIHRELLMRRASLERLCQSSLTITERGSRSENGVAAELLSN HQVLLQEARSRVHSLQEYQTFEEALKAVETWLEDVERKLEKLESTEGNKKEVEEKLERAQ DILLMKGEGEVKLNMAAGKAELAIKSSGEVERGVICSKLQEVEDAWAALLLRAMSCHSRL EWTVNQWDLFVESRAQLQRWLEGVGLEVKGPLEPQLGLREKRKQLERLRLLSSDVEDHQG ALCYLEESAAELYKRTGDPVFKEEEMVLLRAQFEDVKAAAEERVRLSEDVVLEHKKYMET IRELTDWLMVVGEELQQCSDPSGDSPALSRKLTEVRELLERGACEGRERLRRVRLSVERA GRHTAAAGCELMDGEVAALARALHQWEGASLRARDALETAVAAATEAEREQTRLTAQLEG EMEKLEGQLKEWSEGLSSAERRNSGAAAVEGWTVAKGVLEGLQTAEVMEEKLKAQLNELC GFSSDLGLQSDRVSALIKLHNSLSLRASRECQNKEKLLEQRFRSSLHDFRQWMVNANIST AKCFDSPHSIQDASIALQQIQEFKSDEEQGQTRLNAVLTYGEQLSSVMPVDRVQAIRTKV NAAKDDWKSLMDSLLRRETALQVLQSQMQDFEASVEPLQDWLNRSEISVQESSARLHDLP AKRLELSKLQTLLEEMRSRESELAELRGRAHGLWEGQGAGKSFVHQVCQLAACYLALSNL IKEKVSRVERVVGEHQLFSQGLQELQNWVSESQQVLKTCSCPTSDKSVLITRMGQLETLL AACQGREIQLKMLITRGESVQRNTSAEGVPVVRKQIQDLKDSWESLLSTSIQCKSQLEGA LSHWTSYQEDVCQFECWMERVEESLGNSDKHYAEMRDKTANLGRAKLLYEEVLSHSSPLE TIATKGSNMTEHTATQQEIQKLSERYTAIKDKAKAAVSKAEELVLLHQEYQRGLHMFEDW LEQEQNSLAHLSPLDEDVNALENTLKELQMLQSHCPKGHNLLSSVLASRERVIPWGAPQI EDRALETAQTEWQGYQDRLGETKLQVEQALARVQKLEGVFQSLDQWLVDIELKVKVRSHR RSDVSAKEAQLQHLKRWQIEAAQRQAEVEGLSTLAQQVVEDAHVSGRISTRVTQLTARYH ALLLQIQDTLKQLQEEMQNITDAQNALRTFSDWLSTARKNFKIVTERTEALDRITMEKKM KRLESLQGDMDQGHSLLKTLRESAEQAVSFLDDPGASKLEREVQTGRSQLEELILGLREE HATLERSLVLYKDFQERYKSQMQWLRETRALLCSTVEPKAELYQRKAQLNKYKAVEQTLL SRDSAVSFVLEKGETLLTLLHSPSITDNMTRLQADYQELCSSAKTHVHRLEAQVKKQEAY HKDLQEIERWLLQMSSRMVTPDPSSGGGLEAATQQLARHKAIMEEIAGFEERLATLKEKG EELLSGCSERLQARLRQQIQNHQQGARDSYSAICSTAQRVYQSLDWELQKHASLRDTLQL CQTWLSNVQEEIQLPAHAPHCLQEALAQMKQERTLQEQASTYLQLVCSTCDLSDDQVRET AAEIQQVKLQIEERMLESQELADNWREIKDLRSNLECRLLEAEQLLQSMLRRPAELEPKV AQNQLDQAQDFIQEMRARQVDLTQLRESINRLTAGQESPELMEVGRLRCAWLDLGRQAAQ LLEQKEEDLQRSGDYHDCICMVEELFDQLSKKWDQLARGDIESTTECLDALKKLSTDLQD QRCVLDDLRNNRHGILPRLSLEDRDLVKEQVGYLEQRWTQVESLVQQKIQDSAQTLEELS QIEDHLREAQEWAELQQPSLSEVLKTSPPPDLAQSFLFDHLSFCAELEAKHKLLAEAVTD ANSLSTRLGLNERRKLQTLIQEAQTEVESLGTKAAQYRKSLSKVFTERTQFLQALDRAAE WIRKQEQRALADDHVALLPNVLHKQVSTCKSFTSSLRAYQVELTSLWVQGRELVKDATDE EKKETLQKLEELQVTFEASLQKSMEHLQHLEKALVIRKYFKVDLDRICEWLKQAEVATFP IIDLSGNDEELQNQLTEYQQLLDHASEYENLLLIVQRAGQEILPTLNEVDHCYLDEKLNG LPQQYNDMLLLIREKCDRIQQVLLERREFESLIDATRKALKELQEKCDGLEMNSANQSVE EGERLHSNYEDLMKALANLFQGMKDLRVKTQDFLIMGQPYAPEVIDQLVNLHGSLNLQIE CKMKELRKTLNILNDHRAVVEKMDYSITRLKEQLGKFDSNGDEEADAMERLSTLHNLSKC FEEVRSYPEGLKAQKDDLNQHFDSKTLKTQVIFREEQLHTLKQKINAHIEECERGFMGNK DFQTDIKVSVDWLKSFRDRLRHPLMFEEAKIEIVQEEVRSLSALQEQMKSRFRLLEYMTN EEKQKYINDQKPLPKLFETTLMEIPKLQDDLQQAVNTKQVTLQTILSLLQRYYHSLQSVQ QWFEDAVALLEHVSQEADLEKISDCLKDIKNITSQEQTVKRTMQEMQDLVPQMGDFFSPT VMMQIQKHCEDSYHKVTEVFEQLKLRQDNLQRSITQWRSFQDETDEFIRQMNEVEKRMTE FTTARANSEQEAVDKLCLYQNIESQVQGLEDALNGLKEKAAQLDEPAIKDTTSRSVCSLS HRWTRLLSVARAQVKALQDSAFNWRCTREKLEKMRAVCEDLHSRVPDNMVEKASSMAALQ SLLEYHDSFSREVERESSALTLLRHHVLNLFLHSHASASTTDSKHNQDNPCLLEIQSIQE KYDNLLQQVCASRQQVQVELREREEVGRELGLLKGWIQDTQGLLLSPTADLDNLLTDLET AHGGMQSHRQNLEQIADRQQIKYQDLNATLPSEISTQLAEVTLALGSAEDQVQAREREVQ HSRDIKEDFNSRLQDISKKVKLISLKLKQKAIDVEEAKEETEGLFEELEECGHALSELDV AVKEFAEQNPLLAKQLGSSLSKLTELHVQTIRLAEGRTTGLQKAEKNFEDFNEMLTLTLN WTEKAETVVSAHIMWSPASQMQEQIRTHQALLQEWQDLQGEFEGLVERVGLLGDVVQTDA LHQQVAELSRHAEELQQRAKTRLLMLQDAAKDLGRLESDVKSLHQSVERVQETLASPDLA RLSLREQLAQRQLLLSEMEGLKQQVQTMQMCQSALRLPEDVIAALPLCVTAQSLQQESSH LQHNTIQQCNILQEAMVQYEQYEQEVKNLQRLIEEAHRVIQDRPVATGNIQELQTQIQHH EELALKIKGYQEQISALNSKCKMLTVKAKHATMLLTVSEVDGLSDGLEELEDEEEEMPKH PPAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEVSSPPACRSPSPGPNADTSQGSARAP LSRAPLQELYDPSMDSAASANLDDLQRSWETLKNVISEKQKSLYEALERQQHYQETLQSV STKMESIETALNEGLEPSKSPESQMAAHQALMDEILMLQDEISALQACFSQELQLDEDSL EADAGDQLALQSTLTVLGERMATIHMKASGKRQLLEERLSEQLEEQRQEQALQRYHSEAE ELDNWLLSTRATLSSTLQPHPQDMDMEEQLIDCQNMLLEIEQKVLCLSELSVHSESLLME GKAGTRGDAEQLSLKLHSLKSSLLELQRILQNKQTHIQGSLQEQEDTESDSSLSQSPNMM DWLSQARSTRNQQHQDTVQRQRELEEQLGEQKKLLQSVASRGEEILSQRTTPHGESSPAE LSEGDAGQWPESMSTDDQMRVRWENLSKDVNNKLQLSLNTMEQTPCNTLYQPVSSPCGVL RGEQLSQDILSPRSLFEGFSQDLEDMPQTSGTDSKRAHALKRALYEAVSSASSWLDNTEN ELVSGPILLSDDSETHLGHLESLNKEVKNVNEEVCKCRDVLGGTEQLWAGESGEGVLVEE VLDGLEGRLKLLDTVLEQRCDTMKDKLQELTVFQTELRLLLAALSDSKYQLLQKMNAAVD RPASKQMEIVAEAEDSLREFEQKVSEMRSRGETLQPNQLCTQELLKLQDAYEELVEMVGS KRSGINQSLVLKAQYERALQDLVDLLDTAQDKMAADQKMKVGSVIEVQILLDKHKEFFQG LETHVVLTQAFFRQVSGLVVQREVQSLEETVAQAQAVLKQAHKRGVELEGILEWWSRLVG DYQALYRQLEAVESNIPSVGLVEETEDRLSDRIALYQRLKASLSERQQQLYKLLEDGKRL LLHVSCSELETQLTQLGDHWLSTTTKINKELHRLDSTLKHWIRYQCESAELSQWLSSALD RLEFWSTQSVTVPQELETVRDHLHAFLEFSKEVDAKSSLRASVQSQGNQLLRLKKVDTAA LRANLAQVDTQWADLLTRIPVVQEKLHQLQMEKLPSRHAITELMSWISLMENIIQEDQQK IMGAVGSEAVQMYLQKYKGFRIDLSCKQLTVDFVNQSVLQISSQDVEGKRSDKTDFAERL GAMNRRWQILQGLVTEKIQVLEGLLESWLEYENVVQTLKTWFSVQEEKLKKKHRIEDVSS AQNALKDCQEMEVLVKEKEKDLERAEEKGCLLIQDKKGEAGTFIMDTLKGLNQSWANLDH MIGQQTVSLRSVLEQWSLYKQAYEEIQGYLMEGRYTICRLHLLTGSPEAVQVQVENLESL QDELEKQESSLQKLGSITQQLLKNCHPSVSDSLNTALGDVNLRWNTLLEQISDQLRRSKS LLQLWQHYKALHAQSSTDIQKLEDQVEQMLKSATHRDITEQEVKGLMATEGSVESVLQQL DEFSEQLRQQVDPSAMTTFHTDHLSLTQRLATVGHTLQRRQSLLEVGMRDYERFSKEVHS LSHWSEEAEKVLKEPDPIGSPDISSVQEHMEKLKTQMLKLSSLSPDLERLNELGYQLPLN DNEIKRLQNLNRSWSSNSARTIERFSKLQALLLQRQTFLEKCDAWMTFLTQTEEKLGAEI SGNYQSLLDQQREHELFQAEMFSRQQILYSIINDGHQLLNQGQVEDRDEFGLKLALLSNQ WQGVVRRAQQRRGIIDSLVRQWQRYTELIEKLRHWLQEVSVEPEEQQQVSTVALQQIRGM LDHIQLKERVLQRQQGSYILTVEAGRQLLLWADARTEASLHTELTDVQERWRTINIRLDE RKKELLSLLRDWDQCEKGIAASHEKLRDFKQKLSVPLPDHHEELHTEQIRCKDLESSIEG WADDVAGLCILRESLSSGLSADNLTVLQERLILLQRQWEETCHQLSLRRQQVSERLNEWA VFNEKNKELCEWLTQMESKVSQNGDISIEEMIEKLRKDYQEEISVAKENKHQLEQMGERL AQASHESKAAEIQYKLSKVNERWQHLLDLIEARVKKLRETLVAVQQLDKNMSSLRSWLAH IETDLSRPIVYETCDSHEIQRKLKQQQDLQRDIEKHSTGVASVLNLCEVLLHDCDACATE TECESIQQATRGLDRRWRNICAIAMERRIKIEETWRLWQKFLDDYSRFEEWLKVSERTAA LPNSSGVLYTIAKEELKKFEAFQRQVQEFLTQLELINKQYRRLARENRTDSSCHLRQMVH DGNRRWDVLQRRVAAILRRLKHFIGQREEFETARDGVLVWLTEMDLQLTNIEHFSECDVQ AKIKQLKAFQQEISLNMGKMESVFGQGEVLMEKSEPLDAAVIEEELDELQRYCREVFGRV ERYYQKLTRLPLTDDECEGSDREFESGDLSDLQWGEDGTMSQTSSRPPSAGTAPVRTNDS GRDTPASEDSIPLEWDHDYDLDPMGHTMSAQQGREKDEDEELLCLATAALTGEAVRLLDN MMDTSRYSLQETDGTMGGHDTSYMGYMRLMDDCRGSLKAVRRVEGELEEEEDNLSGLSNP DNTETQSTGVIERWELIQAQSADSDHKEREDLVLLQKMTSDLDAMEVWLSQTEAELEELR GKNLSADIHTIEQRIRKLKELQKAVDSHKSKVLSINLNSVTLLQSDSEESQDLKAKLKEM NSRWDRLGKSLKDWRTALQDALMQCQEFHELSHGLLLWLENIDRRRNEIIPIASGLDRHT LQAHYRALKQIQRELLETEQKVDSLQELSGQLLVQAHGSECLEAQERVHVIGNRLRLLLK AVATDLELLEKELQASRNRQDASLWSVTDDADTSGSVSSVSGVTVSTKRQSLRGKCSVSE PGSSARLPRHRLPSGSGCVSSRSGSSGSQGGAAVARCQPFLLRVLWAALPLQLLLLLIVG LTCLVPMTEQDYSCAHANNFAWSFHPMLRYTNGPPPV NT seq 19734 nt NT seq  +upstreamnt  +downstreamnt atggatgcagacatcagtctttacactcgctctcttgagctgtggaatgacattaataaa atggccaatgacattgagtgttggagtgccatctctgtcggtgagctcagtgagggagct gccagtcttctctctgctcacgacatggaaggacacctctctgagttcaagctggagtta gataataaggaagatgaacttaagaacttgcagacaaagatgacacagctacaggaactg atgaaaacccagcacatacacactgaactgcaggtgatggctgcagatctgaggaagcag atttcccatgctgcagaggtgtatgaacagaccaaaggcatgtataaagacttcaagtcc cagaggcagcagcttcaagacctaatttcccagatttcagagcagctgaagacctcagag gactcactgtcagagttttcatcatccgctgacccagagaattttgttaagatcaaggag gttgagaggtcacaaaagcaattagaggtgagtctggatgtagcaagtgagtctctccga gcactgtgtagaacgtatcccactcagcacctggccctgttgggtgatgctgtctcgcac ctggtcaagtggaatgaggaagtgacacaacgccgcagccagatcttggggtctcttcag gacgctcttctgcagcgcttcaacgagaaagcacatgcttttcactgttggctgtctgag ttgagggctggaattgaggactgctttgagcaaacaggagatgctgttgccatttcagcc aagcaacaaaagctcaagactgcagtagaggaagtcatggagggtgaggagcgcttggcc cgtgtttgtgaggatggagagagactcctattgcacctcagcaaatgtgggactggaagc attcaggagcaactggactcttgtcaatatgccttggattcatttgtcatggattgccga cagcgcatacgggccttggaagaaagtgccaacctattaaatggctatgaaacgcgtgtg gtggagatgagcgactggctgaaacagctggaggtgaggctgaagacagatgctcctctg aggggtgagagtcagtctgcagcccccgactgctcaggagaactgagaagagtggaggaa atccacagagagctgttgatgaggagggcgtctcttgagcgtctgtgtcagtcctcgctc acaataacagagagaggatctagatcagagaatggtgtggcagcagagttgctctcaaac caccaggttttgctgcaggaggccaggagtcgagtccatagcctgcaggagtaccagaca tttgaggaagcactaaaggcggtggaaacctggctggaggatgttgagaggaagttagag aaactggagagcacggaggggaataaaaaggaggtggaagagaaacttgagcgagcacag gatatcctgcttatgaagggagagggcgaggtaaaactcaatatggcggctgggaaggca gagctggccataaagagcagtggagaagtggaacgaggagtgatttgctcgaagcttcag gaagttgaagacgcatgggcggcactgcttttgagagctatgagctgccacagtcgattg gaatggacggtcaatcagtgggatttgtttgtggagtctcgtgcacagctgcagagatgg ctggagggagtagggctggaggttaaaggtcctcttgagccccagcttggactcagggag aaacgaaagcagttggagagactgcgcttgctgtcatcagatgtggaggaccaccaggga gctctgtgttatctggaggagagtgcggctgaactttacaaacgcaccggtgaccccgtc tttaaggaggaagaaatggttctcctcagggcacagtttgaggatgtcaaagcagcagca gaggagagagtcaggttgtcagaggacgttgttctcgaacataagaagtacatggaaaca atcagggagctcactgattggctaatggtggtaggggaggagcttcagcaatgctctgac ccatccggtgactctccagccttaagtcggaagttgactgaagttcgggagctgctggag cgcggcgcgtgcgaggggcgcgagcggctgcggcgcgtgcggctgagcgtggagagagcc ggaaggcacacggcggctgcgggctgcgagctgatggatggagaagtggcggcgctggcg cgagcgctgcaccagtgggagggagcatcactacgcgctcgcgacgccctcgagaccgcc gtggccgcggcgacagaggccgagcgggagcagacacggctgacagcgcagttggaggga gaaatggagaagctggagggccagctgaaggagtggagcgagggactgagcagcgccgag cggaggaatagcggagctgcggcggtggagggatggacggtcgccaagggtgttctggag gggcttcagacagctgaagttatggaggagaagctgaaggcgcagctcaatgagctgtgt gggttttccagtgatctaggtctgcagtcggacagagtcagcgctctcatcaagctacac aacagcctaagcctacgagcctcccgggaatgtcagaataaggagaagctgctggaacaa cgcttccgttcttctctgcatgacttccggcagtggatggtcaatgccaacatctcgact gccaaatgctttgactcccctcatagcatccaggatgcctccatcgctctccagcagatc caggagttcaaaagtgacgaggagcagggccagaccagactgaatgctgtcctgacctat ggagagcagcttagtagcgtgatgcctgtcgacagagtgcaggcgatcaggaccaaagta aatgcagccaaagatgactggaagagcctgatggacagcttactgagaagagagacggcc ttacaggtcttgcagtctcagatgcaggactttgaggcaagtgtggaaccccttcaagac tggctgaacaggtctgagatcagtgtgcaggagagcagcgctcgcctccatgacctgccc gccaaaagactagagctctctaaacttcagacgctgctggaagagatgcgctccagagag tctgaactggcagagctgagagggcgagcacatggcctctgggagggtcagggtgctggg aagagctttgtgcatcaggtctgccagctagctgcatgctacttggccttgagcaatctg attaaggagaaagtatcaagggtagaacgagttgtgggggagcatcagctattttcacag ggccttcaggaacttcagaactgggtttcagagtcccaacaggtcctcaagacctgcagc tgccccacatctgacaagagtgtgcttatcaccagaatgggccagcttgagactttattg gccgcttgtcaggggagagaaatccaactaaagatgctcatcaccagaggggagtctgtc cagaggaacacctcggccgagggtgtaccagtggttcgcaagcagatccaggacctcaaa gactcctgggaatcactcttgtcaacatccatacagtgcaaaagccagctggaaggtgcc ttgtcacactggaccagttaccaggaagatgtctgtcagtttgagtgctggatggagcga gtagaagagagcctcggaaactccgacaaacactacgcagaaatgagggacaagacagcc aatctaggccgtgctaaactcctctatgaggaagttcttagccactctagccctttagag accattgcaactaagggttccaacatgactgaacatacagccacccaacaggagatccag aagctcagtgagagatatacagccattaaagataaagccaaggctgctgtcagtaaggca gaagaattggttctgctccatcaagagtatcagcgtgggcttcacatgtttgaagactgg ctggaacaggagcagaacagtttggcccacctctcacccctggatgaagatgtaaatgct ctggaaaacacgttaaaagaactgcagatgctccagtctcattgccctaagggacataac ttgctcagctcagttcttgccagtcgggaaagagtcattccatggggtgcccctcaaatt gaggatcgggctctggaaactgcacagacggaatggcagggctaccaagaccggctcggc gagaccaaactccaggtagagcaggctctcgcaagggttcagaaactagaaggtgttttc caaagcttagaccagtggctggttgacatagagctcaaggttaaggtgagaagccaccgt cgctctgatgtcagtgcaaaagaggcacagcttcaacaccttaagaggtggcagattgag gctgctcaacgtcaggccgaggtggaaggccttagtactcttgcacagcaagtcgtcgag gatgctcatgtcagtggtcggatcagtaccagggttacccagctcactgcccgctaccat gccttgctattacagatacaggatacactcaaacagctccaggaagagatgcagaacatc acagatgctcaaaatgctctcaggaccttctctgattggttgagcactgcgaggaagaat ttcaaaatcgttacagaaaggacagaggctctcgatcgcattacaatggaaaagaaaatg aagaggctagagtctctgcagggtgacatggatcaaggtcacagcctgcttaaaacactt cgagagagtgcagagcaggccgtttcctttctggatgaccctggagcatccaagctagag agggaagtgcaaacaggccgatcacagctcgaagagcttattctggggctacgggaagag catgcaaccctggaaagaagccttgtgctctataaagatttccaagagcgctacaagagc caaatgcagtggcttagggagactcgagcccttctctgttccactgtcgaacccaaagca gaactttaccagagaaaagcccagctgaacaagtacaaggctgtagagcagacgttgcta tctcgtgattctgccgtgagctttgtgctagagaaaggagaaactctgctgaccctcctc cactccccttccatcacagacaacatgaccagactacaggccgactaccaggagctatgt agctcagcaaagacccacgttcacagattggaagctcaggttaagaaacaggaggcgtac cacaaagatctacaggaaattgagcgttggctgttgcagatgtcgagcaggatggtgact cctgacccgtcatcaggcggtggcctggaagctgccactcagcagctagccagacataag gctattatggaggagatagcaggttttgaggagcgtttggctacacttaaggaaaaggga gaggagctgttgtccggttgcagcgagcgcctccaggctcggcttcgccagcagattcag aaccaccagcagggagcaagagacagctactcggccatctgcagcactgcccagcgtgtg tatcagagtctggattgggaactgcagaagcatgcaagtctgcgggatacgttgcaactg tgtcagacgtggctttcaaatgtacaggaggagatacagcttcctgcacatgcaccacac tgcctacaggaggcgctagcacagatgaagcaggaacgaactctgcaggaacaggctagt acctatttgcagctggtgtgctccacctgtgatctttctgatgatcaggtacgagagaca gctgctgagatacagcaggtcaaacttcagatcgaggaaaggatgctggaatctcaagaa ctggcagataactggagagagattaaagacttgcgttccaaccttgagtgtcgtcttctt gaggccgaacaactcctccagagcatgttaaggaggccagctgagcttgagccaaaggtt gctcagaaccagctggaccaggctcaggactttatccaggagatgcgagccaggcaggtt gatctgacccagctgagagagagcatcaataggctaacggctggtcaggagtcccctgag cttatggaagttgggcggctgcgctgtgcttggctggatctgggcagacaggctgcacag ctgctggaacagaaagaggaggatctacagaggagtggggactatcatgactgcatttgt atggtggaggagttgtttgaccagctgtccaagaaatgggatcaattggccaggggagat attgagagcacaactgagtgtctggatgccttaaagaagttatccacagacctgcaggac cagagatgtgtgctcgatgacctgagaaataataggcatgggatcttgcctcgtctgagc ttagaagacagagacctggttaaggagcaggtgggttacctggagcaacgttggacccag gtggagtcgcttgtccagcagaaaatacaagattcagcgcaaacactggaagaactcagt caaatcgaggaccatttgcgggaggctcaggagtgggctgagttgcagcagccatccctg tctgaggttctcaagaccagcccccctccagatttggcccagagctttctgtttgatcac ttgagcttttgtgcagaattggaggccaaacataagcttctggcagaggccgtgacagat gccaatagtctttccactcgtctaggtcttaatgaaaggaggaaactgcagactttgatc caggaagcacagacagaagtagaatcgcttggaactaaggctgctcagtatcgtaaaagc ctcagcaaagtatttacagaacgaacgcagttcctacaagccctcgacagagcagctgaa tggatcagaaagcaagagcagagggctcttgcagatgatcatgttgctctcctaccaaat gtactgcacaagcaggtgtcaacttgtaagagttttactagcagcctaagagcatatcag gtggagctaacttctctttgggtacaaggacgagaattagtgaaggatgccactgacgag gagaagaaggagacccttcagaagctggaggagttgcaagttacctttgaggcttccttg cagaagagcatggagcatctgcagcatctggagaaagcgctagtcattcgaaagtacttt aaagtggaccttgacaggatctgtgagtggctaaaacaagcagaggtagctacatttccc attattgacctgagcgggaatgacgaggagcttcagaaccagttaaccgaataccaacag cttcttgatcatgcttcagagtatgaaaaccttttgctcatcgtccaaagggcaggacag gagatacttcccaccttaaatgaggtcgaccactgctacctagatgagaaacttaatggc cttccacaacaatacaatgacatgctgttgttgatcagagagaaatgcgacaggatccaa caagtgcttttggagcgcagggagtttgagtccctcatcgatgccacacgcaaggctttg aaggaacttcaggagaagtgtgatggtttagagatgaattcagccaaccaaagtgtagaa gagggagaaagattgcacagcaactatgaagatctcatgaaagctcttgcaaatctgttt cagggaatgaaagatcttagggttaaaactcaggatttccttatcatgggtcagccatat gctcctgaagtcattgaccagctagttaatctccacggcagtcttaacttgcagatcgag tgtaagatgaaagaattaaggaaaacattaaacatattaaatgaccatcgagcagtagtt gagaaaatggactatagcattactagactcaaggaacagcttggcaaatttgactccaat ggagatgaggaggcagatgccatggagagattatctactctacacaatttatcaaaatgt tttgaagaggttcgttcctatccagagggtctcaaagcacaaaaagatgacctcaatcag cactttgactcaaagacccttaaaactcaggttatcttcagggaggaacaacttcatact ttaaagcaaaagattaatgcacacatagaggaatgtgagagaggttttatgggaaataag gattttcaaactgatattaaagtatcagtagactggctcaagagttttagggatcgatta agacatccattaatgtttgaagaagcaaaaattgaaattgtgcaggaggaggtcaggtca ctgtcagcacttcaggaacaaatgaaatctaggtttagattattagaatatatgactaat gaagagaaacagaagtacataaacgaccaaaagccattgccaaaactctttgagaccact ttaatggaaattccaaagctgcaggatgatcttcaacaagcagtaaacaccaaacaggtg accttgcagactattctgtctctgctccagagatactaccattctttgcaatccgtccag cagtggtttgaggacgcagttgctcttcttgagcatgtttctcaagaggcagacctggag aaaatttcagactgcctcaaggacataaaaaatataacaagccaggagcaaactgtcaag cgtacaatgcaagaaatgcaagatctggtacctcaaatgggtgactttttcagccctact gtaatgatgcaaatccagaaacattgtgaggattcttatcacaaggtaacagaggtcttt gagcagctaaaactacgtcaagacaacttgcaaagaagcataactcagtggagatccttt caagatgaaacagatgaatttatcaggcagatgaatgaagttgagaaaaggatgaccgag ttcacaactgccagagcaaactctgaacaagaagctgtagacaagctttgtttatatcag aatattgagtcacaagttcagggtcttgaagatgcactgaatggcctgaaagaaaaagca gcacagcttgatgagcctgccataaaagacactacttctcggtcagtctgttcactgagc catcggtggactcggttgctcagcgttgctcgagctcaggtgaaagctctccaggactct gcatttaactggagatgcaccagagagaagctggagaaaatgcgggctgtctgtgaggac ctgcacagtcgtgttcctgacaacatggtagaaaaagcctctagtatggcagccctacag agccttctggagtaccacgattccttcagtcgagaggtggagagagaaagcagcgccctg accctcctcagacaccatgtgctcaacctgttcctccattctcatgcctctgcatccacc acagacagtaaacacaaccaagacaatccatgtctgctggaaattcagagcattcaggag aaatatgacaatctgttacagcaggtgtgtgcaagcagacagcaggtgcaggtggagctg cgggagagagaggaagtggggagagagttgggcctgctgaaaggatggattcaggacacc caggggctgctgctaagccccacagcagacctggataacctgcttactgacctggagacg gctcatggaggcatgcagtctcaccgccagaaccttgagcagattgcagatcgtcagcag ataaaataccaggatctcaatgccacccttccttcagagatcagcacccagctggcagag gttacactggctctgggttctgcagaagatcaggtacaggcacgggaaagagaggtccaa catagcagagatattaaagaagactttaactccagacttcaggatatctcaaagaaagtc aaactcatctctttgaagctcaagcagaaggctatagatgttgaggaggctaaagaggag acagagggtctatttgaggagctagaggagtgtggtcatgctctgtctgagctagatgtg gcggtgaaggagttcgctgagcaaaatcctctcctagccaaacagctgggctccagcctg agtaaactgactgagcttcatgttcagaccatccgactggcggagggaaggaccacaggc cttcagaaggcagaaaagaactttgaggattttaatgaaatgctgacgttaactctcaac tggacagaaaaagcagagactgtggtgtcggcacacatcatgtggagtccagcctctcag atgcaggagcagatcagaacccatcaggccttattgcaagagtggcaagatctccaagga gagtttgagggtctggtggagagggtgggactgctgggggacgtggtccagacagatgct ctccaccagcaggtggcagaactgagcagacatgctgaagagctgcagcagagagccaaa acaagactcctgatgctacaagatgcagccaaggacttggggagactggagagtgatgtg aagagcctccatcagtccgttgagagagtccaggagactctggcctcccctgatctggca cgtctcagtctccgagaacagctggctcaaagacagctgctgttgtcagagatggagggt ctcaagcagcaggttcagactatgcagatgtgtcagagtgccctccggctgccagaggac gtgattgctgctttaccgctgtgtgttactgcacagagtctgcagcaagagagcagccat ctccaacacaataccattcaacagtgcaatatattacaggaggccatggtgcagtatgag cagtacgaacaggaagtcaagaacctacagagacttattgaagaagcacaccgtgttatt caagaccgccctgttgccacaggaaatatacaggagcttcagacacagatacaacatcat gaggaattggccctgaagataaaaggataccaggagcagatctcagccttgaactccaag tgtaagatgttgacagtgaaagccaaacatgctaccatgctgctgacggtcagcgaggtc gatggactctctgacgggttagaggagctggaggatgaggaggaagagatgcccaaacac ccaccagcacacccctctgttgtcatgatgacggcaggtcgttgtcatactctcctctcg ccggtcacagaggagtctggtgaggagggcaccaacagcgaggtctcctctccccctgcc tgcagatcgccctcccccgggcctaacgctgacacctctcagggttcagcgcgagctcct ttaagcagagctccactacaggagctttatgacccctccatggactcagctgcctcagct aatctggacgacctacagcgctcatgggagactttgaagaatgtgatcagcgagaagcag aagagcctatatgaagctctggagaggcagcagcactatcaggagaccctgcaatctgtc tccacaaagatggagtccattgagaccgcactaaatgaaggcttggagccaagcaagagt cctgagagccagatggccgcccaccaggctttgatggatgagatcctgatgctccaggat gagatcagtgcattgcaggcctgcttctcccaagagctacagttggatgaagacagtttg gaggcagatgccggagaccagctggctctgcagtcaaccctcactgtgctaggagaacgc atggccaccatccacatgaaggcctccggaaagcgccaacttttggaggagcgattaagt gagcagttagaagaacagaggcaggaacaagcgctacagcgttatcatagtgaggcagag gagcttgacaactggctgctcagcacacgtgccacactgagctccactctccagccacac ccacaggacatggacatggaggaacagctgattgactgccagaacatgttattggagatc gagcagaaggtgctgtgtctgtccgagctgtcagtgcacagtgagagtttgctgatggag ggtaaggccggcacacggggagacgctgagcagctctccctcaaactgcacagcctcaaa tccagcctgctggagttacagcgcatcctccaaaacaaacagacccacatccagggctca cttcaggagcaggaggacactgaatcagactcgtctctctctcagagccccaatatgatg gactggctcagtcaggcgcgatccacacgcaaccaacagcatcaagacacagtgcaaaga cagagggaattagaggagcagcttggcgaacagaagaagttactgcaatctgtggcatct agaggagaggagattctctcacagcggacaacacctcatggagaaagttctcctgcagaa ctttctgaaggggatgctggtcagtggcctgagagcatgagcactgatgatcagatgaga gtcagatgggagaacctgagcaaagacgttaacaacaaactgcagctgtcactaaacaca atggagcagacgccatgtaacacgctgtaccagccggtatccagcccttgtggagtttta agaggagagcaactgagtcaggatatcctgtctccacgaagtctgtttgaaggcttcagc caagatttggaggacatgcctcagacaagtggcactgacagtaagcgtgctcatgctctg aagagagctctctatgaagcggtttcgtcagcttcctcctggctggacaatactgaaaat gagcttgtatctggcccaatattactatctgatgactcagagactcacctgggccaccta gagagtttgaataaggaggtaaagaatgtcaacgaggaggtgtgtaaatgtcgggacgtg ctcggaggaacagagcagctatgggctggagaaagtggagaaggtgttttggttgaggaa gtgttagatggtttggaggggagactgaagctgctggacacggtgctggaacagagatgt gacaccatgaaagacaagctgcaggaactcactgttttccagactgagttgaggctgttg cttgcagcactcagtgactcaaagtaccagcttttgcagaaaatgaacgcggctgtggat cgacccgcttctaaacagatggagatcgtagcagaagcagaggacagtttgagggaattt gaacagaaagtttctgagatgaggagcagaggagagacactgcagcccaaccagctctgc actcaagagctgctcaaactacaggatgcttatgaagagctggtggagatggtgggctcc aagcgaagtggaataaaccagagtttggttctgaaggctcagtatgagagagctttacaa gacctggtagatcttctggacaccgcccaggacaaaatggctgctgatcagaagatgaaa gtgggatcagtgattgaggtccagattcttctagataaacacaaggagtttttccagggg ctagagacgcatgttgttctgacacaggccttcttcaggcaggtcagtgggttggtggtg cagcgggaggtccagagcttggaagagactgtggctcaggcccaggctgtgcttaaacag gctcacaaacgaggagtggagctggagggcatcctggagtggtggagcaggttggtgggt gactatcaggccctgtacagacagctggaggcagtggaaagcaacatccccagtgtaggg ctggtggaggagacggaggacagattgagcgatagaattgctttgtatcagcgtttgaag gccagtctctctgagcggcagcagcagttgtataaattgttggaggatggaaagaggctg cttttgcatgtgtcctgctcagagctggagactcaactcactcagctgggggaccactgg ctcagcaccaccaccaagatcaataaagagctacaccgcctggactccaccctcaaacac tggattaggtatcagtgcgagtcagctgaacttagccaatggctgagttcggcactagac cgcctggagttctggagcactcagtctgttacagttcctcaagaactagagactgtcaga gaccatcttcatgcattcctggagttctccaaagaggtagacgccaagtcttctttacgt gcctcagttcagagtcaggggaatcagcttctccggttgaagaaagtggacacagcagct ctcagggcaaacttggcccaggtagacacgcaatgggctgatcttctcactcgtatccct gtggtccaggagaaactacaccagctgcagatggagaagctgccatcccgtcatgcaata actgagctaatgagctggatatccctcatggagaatattatccaagaggatcagcagaag atcatgggggcagtgggatcagaggctgtgcaaatgtaccttcagaaatacaagggtttt cgaattgacctgtcctgtaagcagctgacagtggattttgtgaatcagtcagttctgcaa atcagcagtcaggatgtagaggggaaacggagtgacaaaacagactttgctgagcgtctt ggggccatgaaccgccgctggcagatactgcagggactcgttacagagaagattcaggtt ttagagggtctgcttgaaagctggttagagtacgagaacgtggttcagaccttgaagacc tggtttagtgtacaggaagagaaactcaaaaagaagcacaggattgaggatgtttcctca gcccagaatgcactcaaagattgtcaggaaatggaagtgttggtaaaggagaaagagaag gatctggagagggctgaagaaaaaggatgcttgttaattcaggataagaaaggcgaagca ggcacttttataatggacactctaaagggtctaaaccagtcttgggccaatctggatcac atgattgggcagcagacggtcagtctccggtcagtgctggagcagtggagtctgtataaa caagcatatgaggagattcagggctacctgatggagggacgttacaccatctgtcgtcta catcttctcactggctccccagaagctgtgcaggttcaagtggagaaccttgagagttta caagacgagttggagaaacaggagagcagtttacagaaactgggctccataacgcaacag ctgctgaagaactgtcatccctcagtgagcgattcactcaacacagctctgggtgatgta aacctcaggtggaacacgctgctcgagcagatctcagatcagctgaggaggagtaagagc ctgctgcaactgtggcagcattacaaagcgctccatgctcagagcagcactgacatccag aaactagaggatcaagtggaacagatgctcaagagcgccacccacagggacatcacagaa caggaagtgaagggccttatggcgactgagggatccgtagagtctgtcctgcagcagctg gatgagttttcagagcagctgaggcaacaagtggacccctctgccatgacaaccttccat acagaccacctgtcactcactcagcgattagcaacagttgggcataccctccaaagacgg cagtctctgctagaggtgggtatgagggactatgagaggttcagtaaggaggtacattct ctgagccactggtcagaagaagctgagaaggttctgaaggaacccgacccaattggttct ccagatatctcatctgtgcaggaacacatggaaaaacttaagacccaaatgttaaagctg agcagtctttctcctgatctggaacgtttgaatgagttgggttatcagcttcccctcaac gataatgaaatcaagcgtctgcagaacctaaacaggagctggtcgtctaactctgctcgc acgatagagagattcagcaaattgcaagcactgctattgcaaagacagacctttttggag aagtgtgatgcttggatgaccttccttacccaaacagaagagaaacttggcgctgagatt tctggaaactaccagagcctactagaccagcagagagagcatgagctattccaagcagag atgtttagtcgacaacaaattctatactctatcatcaatgatggacatcagctcctgaat cagggacaagtggaagacagggatgaatttggcttgaaactggcactgcttagtaaccag tggcaaggtgtggtgaggcgggcccagcaaagacgggggattattgacagtttggttcgg cagtggcagcgctacacagagctgatagagaaactgcgtcactggctgcaggaagtgtca gtggaaccagaggagcaacagcaagtgtcaacagtagcactacagcagatccgtggcatg ttagaccacatacagctgaaggagcgtgtgctccagaggcaacagggcagctacatcctc acggtggaggccgggaggcaactcctcctgtgggctgatgccagaacagaggcctcactt cacactgagctgactgatgtgcaggagcgctggaggaccattaacatccgtctcgacgag aggaagaaagaactgctctctttgctaagggactgggatcagtgtgaaaaagggatcgct gcatcacacgagaagctgagggactttaagcaaaagctctctgtgcctttacccgaccac catgaggagctgcacacagaacagattcgctgcaaggacctggagagcagtattgaaggc tgggctgatgatgtagccggcctgtgtattctgagggaatctctctccagcggcctcagt gctgataacctcacagtcctacaggagagacttatattactccagagacagtgggaggag acttgtcaccagctgtccctgcgcaggcagcaggtgagcgagaggctgaacgagtgggcc gtgttcaatgagaagaacaaagagctgtgtgagtggctcacacaaatggagagcaaggtc tcacagaacggcgacatcagcattgaggagatgattgagaaactcaggaaggactatcag gaagagatctcagtggccaaggagaacaagcatcagctggaacagatgggggagagattg gctcaggccagccatgaaagcaaagctgcagaaatccaatacaaactcagcaaagtcaat gagcgctggcagcatctgcttgaccttatagaagctagggtaaagaagttgcgcgagaca ctggtggccgtgcagcagctggataagaacatgagcagtttgcgctcctggctggcacac atcgagactgacctctcacgacccatcgtctatgaaacctgtgactcacatgagatccaa agaaaactcaagcagcagcaggatctgcagcgcgatatcgagaagcacagcacaggtgtg gcatcagtactgaacctgtgtgaggtgctgctgcacgactgtgacgcctgcgccacagag accgagtgtgaatccatccagcaggccacacgcggcctcgatcgccgctggagaaacatc tgtgctattgccatggagaggaggattaagattgaggagacatggaggttgtggcagaag tttctggatgattactcccgttttgaagagtggctgaaagtgtcagagaggaccgcagct ctgcccaactcctctggagttctgtacaccatcgctaaagaggagctcaagaagtttgag gcatttcagaggcaggtacaggagtttctgacccagctggagctgatcaataagcagtat cgaaggcttgcacgtgaaaaccgcacagactcatcctgccatctacgacaaatggtgcat gatgggaaccgacgctgggatgtactacagaggagagtagctgccatcttgcgcagactt aagcattttattggtcagcgagaagagtttgaaaccgcccgagatggtgttctggtatgg ctgactgagatggatctgcagctcaccaacatcgagcatttctcagagtgtgacgttcag gccaagatcaaacaactaaaggcgttccagcaggaaatcagtctgaacatggggaagatg gagagcgtttttgggcagggggaggtgctaatggagaagagtgagcctctggatgctgct gtcatagaggaggagctggatgagctgcagagatactgtagggaggtgtttggtcgagtg gagcgctactaccagaaactcacacgcctgccgctcaccgatgatgagtgtgaaggctct gatcgtgaattcgagtcaggtgacctctcagaccttcagtggggtgaggatggtaccatg tcccagacatctagcagaccaccttcagctggcactgctcctgttcgcacaaacgactcc ggccgggataccccggccagtgaagactccatccctctggaatgggaccatgactatgac ctggaccccatgggccataccatgtctgcacaacagggcagagaaaaagatgaggatgag gagttactgtgtttggccactgcagcacttacaggtgaagcagttcgattgttagacaat atgatggacaccagccgctacagcctccaggaaacagatggcactatgggtggccacgat acgtcttacatgggctatatgaggctaatggatgattgccgtgggagtctgaaagcagtc aggagggttgagggcgagctggaggaggaagaggacaacctgtcaggcctgagtaaccct gataacacagagacacagagcacaggtgtcattgagcgttgggagctgatccaggcgcag tctgctgattcagatcacaaagagagagaagacctggtgctattgcaaaagatgacctct gacctggacgccatggaggtgtggctcagccagactgaggcggagttagaagaactgaga gggaaaaatcttagtgcagatatacacactattgagcagagaattagaaaactcaaggag ttacagaaggcagtggattcccataagtccaaagtactgtccatcaacttaaatagtgtc acactgctccagtcagactctgaggagagccaggatctcaaagcgaaactgaaggagatg aactcacgctgggatcgactggggaaatcacttaaggattggagaacagcacttcaggat gctctgatgcagtgtcaggagtttcatgagctgagtcatggtcttcttctctggctggaa aacattgaccgtcggagaaatgagattatcccaattgcatcggggctagatcggcataca cttcaagctcattacagagcactaaagcaaatccagcgggagctgttggagactgagcag aaggtggacagtctgcaggagctctcaggacagctgttggtgcaggcacacggcagcgag tgtctggaggcccaggagagggtgcacgtcatcgggaaccgtctgcgcctgctcctgaaa gctgtggccaccgacctggaactgttagaaaaagagctccaggcttctaggaacagacag gatgcctccctctggtctgtcacggatgacgcagatacttctggatcggtcagttctgtt tcaggggtcaccgtttccactaaacgacaatcgctacgaggcaaatgtagtgtgtcagaa ccaggatcctcagccagacttccacgtcacaggttgcccagcggttctggatgcgtttcg tctcgctctggttcctccgggtcacaaggtggcgctgctgtggctcgctgccagcccttt ctgctgcgagtgctctgggcggctctgccactgcagctccttctgctgctcatagtgggc ctgacctgtctggtgcccatgactgagcaggattacagttgtgcccacgcaaacaatttt gcctggtcttttcatcccatgcttcgctacaccaacggcccaccgcctgtatga

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