Chryseobacterium gleum: NCTC11432_02534
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Entry
NCTC11432_02534 CDS
T07042
Symbol
thrA_1
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
cgle
Chryseobacterium gleum
Pathway
cgle00260
Glycine, serine and threonine metabolism
cgle00261
Monobactam biosynthesis
cgle00270
Cysteine and methionine metabolism
cgle00300
Lysine biosynthesis
cgle01100
Metabolic pathways
cgle01110
Biosynthesis of secondary metabolites
cgle01120
Microbial metabolism in diverse environments
cgle01230
Biosynthesis of amino acids
Module
cgle_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
cgle00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC11432_02534 (thrA_1)
00270 Cysteine and methionine metabolism
NCTC11432_02534 (thrA_1)
00300 Lysine biosynthesis
NCTC11432_02534 (thrA_1)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC11432_02534 (thrA_1)
Enzymes [BR:
cgle01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC11432_02534 (thrA_1)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC11432_02534 (thrA_1)
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GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
ACT_7
NAD_binding_3
ACT
FNIP_M
Motif
Other DBs
NCBI-ProteinID:
VEE08199
UniProt:
A0A3S4PF93
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All DBs
Position
1:2674318..2676765
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AA seq
815 aa
AA seq
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MKVLKFGGTSVAHSQNILLVEKIIKSESVKNRVVVIVSALHGVTDQLIKAAENASVKDEK
YIQIIQNLEEKHINLVKELFPIAEQSSWLSFVKKHFNDIEDLCNGISVLGELTCRIKDKI
ASYGEFLSSKIITARLQHQELDCVWMNSADLIRTDSNFTHAKVDLGCTEKNIVSFLNENQ
NRIIVGPGFIASDEKNNATTLGRGGSDYTASIIAASVHAEELQIWTDVSGMMTADPRLAS
NAKPISEISYHEAMELSHFGAKVLYPPSIQPVMVKNIDLIIKNTFDPDAQGTLISHQLKS
FENERQVAVGISNMNHIALLTLEGSGMVGIPGISAKLFQCLSQEKINIILITQGSSEHSI
TVAIEEKDALRAEYSINSSFADDINLKRVFPVKIETGLSIVALVGENMKSRSGVSAKMFG
CLGNNGINIRAIAQGSSERNISIVISEKDSKKAVNVLHEEFFESEIKQIHLYICGTGNVG
SKLVQQIYNQNDYLKENFLINLRIAGISNSQHMLFADQGISEENYLTWDQQGQKASAGKF
AEEIIRRNLRNSVFVDVTASADVPEIYESLLKRSVNIVACNKIAASSDFKQYKTLKDTAR
NHNCNFYFETNVGAGLPVIGTINDLIKSGDKIQSIKAVLSGTLNFVFNEYDGSRTFSEVV
AQAQKEGYTEPDPRLDLSGKDVARKILILAREAGYPLQFEEIENISFLPEECMEGSVDNF
YEKLTTYEDHFKNLLNNAKNEGKILKYVAEFEDGKAKVGLQHIAPESDLFHLYGKDNIVI
FKTLRYSEQPLVVKGAGAGADVTASGVFADIIRSI
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgaaagttttaaaattcggcggaacatcagtcgctcattctcaaaatatcttactggtg
gaaaaaatcataaaaagtgaatctgtaaaaaacagagttgtcgtaattgtatcagcgctt
catggtgttacagatcaattgatcaaagcagctgaaaatgcttctgtaaaagatgaaaag
tatattcagatcattcaaaaccttgaggaaaaacatattaacttagtgaaagaacttttt
cctattgcagaacaaagttcatggctgagttttgtgaagaaacattttaatgatattgaa
gacctttgtaacggaatctctgttcttggtgagcttacctgcagaatcaaagataaaatt
gcttcttacggagaatttctgtcttccaaaattattaccgcaagactacagcatcaagaa
ctggactgtgtgtggatgaattccgcagaccttatcagaacagacagtaatttcactcat
gccaaagtagatttgggttgtactgaaaagaatattgtcagttttctcaatgaaaatcag
aaccgtatcattgtaggcccgggttttatagccagcgatgaaaaaaataatgcgacaaca
ctgggaaggggcggttcagattacacagcttctatcattgcagcttctgttcatgcggaa
gagcttcagatatggactgacgtcagcggaatgatgactgcagatccccgtcttgcttcc
aatgccaagcctatttcagaaatatcttatcatgaagcaatggagctgtcccactttgga
gcaaaagtgctttatccaccttccattcagcctgttatggttaaaaatattgatctgatc
atcaaaaacacgtttgatcctgatgctcagggaactttaatttctcatcagcttaaatct
tttgagaatgaaaggcaggttgcggtaggaatttcaaatatgaaccatattgccctgctt
accctggaaggcagcggaatggttggaattcccggtatttcggcaaaattattccaatgc
ttaagtcaggaaaaaataaatataattctgattacccaaggatcttcagaacattccatt
actgtcgccattgaagaaaaagatgctttacgggctgaatattcaatcaacagttccttt
gctgatgatatcaacctgaaaagagtttttcctgtaaaaattgagaccggtctttccatt
gtggctttagtaggagaaaatatgaaaagcagaagcggagtcagcgcaaagatgtttgga
tgtctcggaaataacggcatcaatataagggctattgcacagggatcctctgaaagaaat
atcagtattgtcatttcagaaaaagacagtaaaaaagcggtgaatgtacttcatgaagaa
ttctttgaatctgaaatcaagcagatccatctttatatctgcggaacagggaatgtaggt
tcaaaactggtccagcaaatttataatcagaatgattatttaaaggaaaattttttaatc
aatctgagaattgcaggaatttccaacagtcaacatatgctatttgcggatcaggggata
tctgaagaaaattaccttacctgggatcagcagggacaaaaagcttctgccggaaaattt
gctgaagaaatcatccgcaggaatctgaggaactctgtttttgttgatgtaacggcaagt
gctgatgttccggaaatttatgaaagtttactgaagagaagtgtgaatattgttgcctgt
aataaaattgcagcttcttcagattttaaacaatataaaacattaaaagacactgcaaga
aatcacaactgcaatttttattttgaaaccaatgtaggtgccgggcttccggttatagga
accattaacgacctgatcaaaagcggagataaaatccaatctattaaagctgtattaagt
ggaacattgaattttgtctttaatgagtatgacggcagcagaacattttctgaagtggta
gcacaggctcagaaggaaggatacacagaaccggatccgagacttgatctttccggaaag
gatgtggcaagaaaaattttaattctggcaagagaggcaggatatccgcttcagtttgaa
gaaattgaaaatatcagttttctaccggaagaatgcatggagggaagtgttgataatttt
tatgaaaagcttacaacgtatgaagatcattttaaaaacttactaaataacgccaaaaac
gaaggtaaaatactaaaatatgttgcagagtttgaagatggaaaagctaaggtgggatta
cagcatattgctcccgaaagtgatctgtttcatctttatggtaaagataatattgtcatt
ttcaaaaccttgagatattctgaacaaccattggttgtaaaaggagcaggtgccggagct
gatgtaacagcaagcggagtttttgcagatataatccgttctatttaa
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