Cottoperca gobio: 115004005 Help Entry 115004005         CDS       T07513                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism cgob  Cottoperca gobio Pathway cgob04020   Calcium signaling pathway cgob04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cgob00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     115004005 (ryr3)    04020 Calcium signaling pathway     115004005 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cgob04040]     115004005 (ryr3) Ion channels [BR:cgob04040]  Voltage-gated cation channels   Ryanodine receptor    115004005 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY MIR RIH_assoc Ion_trans EF-hand_7 DSHCT Motif Other DBs NCBI-GeneID:  115004005 NCBI-ProteinID:  XP_029281825 Ensembl:  ENSCGOG00000016591 UniProt:  A0A6J2P8K0 LinkDB All DBs Position 24:4283312..4393099 Genome browser AA seq 4629 aa AA seqDB search MRLCHGHDESLTIPGAEKSEEEQRIVNYEAGKGASKARSLWRLEPLRISWSGSHIRLGQA FRLRHLATGHYLAMTEDRGLVLQDREKSDTTATAFCFRPSKEKGDSGPKRDIEGMGVAEI KYGDSVCFIMHVASGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESR AARIIRNSTFLFTNFIKALDSIAEGESTAVADYVEEVLQTLNDLIEYFKQPDSELEHEEK QCLLRSLIKRQDLFKDERMLALLSKCIDRMNLYNSAAHFGEVAGEEAGSAWKDILNLLYE LLAALIRGNRNNCTQFSRNLDWLVSKLERLESSSGILEVLHCILVESPEALNIIQKGHIK SIISLLYKNGRNYKILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSM RPNIFLGVAEGSAQYKKWYFELVIDQVDHFVTGEPTHLRVGWANTEGYAPYPGGGEGWGG NGAGDDLYSYSFDGLHLWSGRVPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPV QGMFEDFNTDGFFFPVVSFSAGVKARFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVE PVKDYKRDHDGVRDLLGTTKFLSQASFIPTPVDTSQIVLPTHLDNVRDKLAENIHELWGM NKIELGWTYGKVRDDNKRQHPCLVDFGKLPETERNYNVQMSSETLKTLLALGCHVVQAYV NAEDDLKKIKLPKDYMMSNAYKPAPLDLSDVKLTAGQEFLVDKLAENAHNVWAKDRIKQG WTYGIQQDLKSRRNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEALHVM DDQNIDTIRFFRVEQTYALKTGKWYFEFEALSGGDMRVGWARPGCRPDVELGTDDQAFVF DGFQGRRMHAGARYFGQPWKKGDVVGCMINMEDKSMIFTLNGELLITSKGSELCFTDFET EDGFIPVCSMAMAQVGHMNLGKDASTFKYYTMCGLQEGFEPFGVNMNRDITMWFSKRLPT FVNIPKDHMHIEVTRIDGTVDSPPCLKVTHKTFGTQNSNSDMTYCRLSMPVEFYSADKIL DESLKLSHPPKEDGTVDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFSLNKM RTVTVTLGDERGRVHESVQRSNCYIVCGADAVGPSSSSRSNSDLEIGCLIDLATGLVSFT ANGKELSTTYQVEPNTKLFPAVFVRPTSANLFQMEFVKIKDAMPLSSAIFKSEHRNPVPQ CPPRLDVQTIMAVLWSRMPNTFLTVETARVSERHGWVVQCLEPLEMMAVHIPEENRCLDI LELSELEDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQFLSGMLREG FYNVLISIHLETAKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVDLSTSLKPRV NFSAVGIINTKRQQFLYSPQIPLGSLKEKAISMLSEAVQGGGTHIRDPVGGSVEYQFVPI LKLIGTLLIMGVLTREEVRMILLLIDPNVFGEAKEGEDAKGDEGVSREKEEVSKNEEKAV EAGEEETKESKPLIKGLLEKSLPEPVKRQMCELLHYFCDCELKHRIESIVSFSDSFVSKL QFNQKFRYNELMLAFNMSAAITAKKTKEFRSPPHEQINILLNFSAGEDCPCPEDIQDELN SFHEELRLHCGIPVEEEEEEQDTSIKGRLLALLYKIKGAPHKTEAEPTEKEQAAPTNLKE LISQTITSWAQESHIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAINLL VSLGQIRSLLSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLG GDKLQEITFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPL DVAASSVMDNNGLSLALEESDLEKVVTYLAGCGLQSCAMLLAKGYPDLGWNPIEGERYLS FLRFVVFCNGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISDNPALD LPKTAAGVNTGSSEEEEEIIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAI LRSLVPTIDLVGIISIPLSLPVLNKDGTVTEPDMSACFCPDHKAPMVLFLERVYGIEDQS FLLQMLEVGFLPDLRASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFSSTEHYA QLIDSTLQTVYRLSKGRSLTKAQRDAIEECLLAICKHLRPSMMQQLLRRLVFDVPMLTEY CQIPLQLLTNHYDQNWKYYCLPSGMISCGIASEEELLLTKKLFWGIFDSLSQKKYDADLF KMATSCLCAIAGAIPPDFVDASLGATLEKQASVDAQGNFDPKPINTANISLPEKLEYIAN KYAEHSHDKWSSEKVSAGWKHGDSLDDQAKTHPLLKLYKALSEKERETYRWPVKESLKSM LAMGWSIERSKEGDAMFQQRESEKQKLSDAQNDGFTPAPMDLNNVPLSRELQGMVEVVAE NYHNIWSKKKKTELVSKGGGTHPLLVPYDTLTAKEKYRDREKAQELFKFLQISGYAIIRD LKDMEQDSSSMEKRFSYKFLKRMLKYIDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAK VLLPLTDQTFKNHCLYFLSTPSKGLSSCGCASNKEKEMVTSLFCKLAALVRHRISLFGSD SAMMVSCLHILTHSLDTRTVMKSGSELVKAGFRAFFENAAEDLEKLLEMLKLGKFMQSRA QMKSVTQSINYVTVALLPILTALFEHITTYEFGVDLLLNDVQLSCYRIVASFYCLGTGKN VFVERHLPVLGESLATLVAAMPVAFLEPQLNTHNPLSVFNTKTPRERAILSMPDTVLEMC PEMPRLEGLLKDVSDVSESGARYSDMPQVIEVILPMLCNYLSYWWDKGPENSPPGAQCCT MVTSEHLSIILANILKILNNNLGIDDAPWMKRIAVYSQPIICKAAADLLRTHFLPTLEKL KNKTVKVVGEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRCRWLK EPDADSTELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKAKMSKSGGDQ ERKHKRRRGEYYSVQTSLIVAALKKLLPIGLNLCSPGDQELISIAKIRYSLKDTDDEVKE HLRQNFHLQDKSDDPAVQWQLNLYKDVVMKSEEPANSEHTVDRVQSISAAVFYLEQVEQP LRNKKCVRQKLLSKQRKRAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEK LVQDLAKTPMKIVEEEEEEVAEIQPDPLHQLILHFSHNALTERSYLEEDPLYIAYADMMA KSCAEDEEEEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPM VTCTLKLGISILNGGNVQVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKA EGLGMVTEEGSINNQRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVN IIISTVDYLLRLQESISDFYWYYSGKDVIDENGKVNFSKALSVAKQIFNSLTEYIQGPCI GNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMIVMLLSLLEGN VVNGTIGKQMVDTLVESSNNVEMILKFFDMFLKLKDLTSSDTFKANDPEFKGIISKKEFQ RSMENQMQYSQSEIEFLLSCADADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHM PHDSRLSTFLDLAESVLSYFEPYLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESK RQFIFDVVNEGKESEKMEMFVNFCEDTIFEMQLASQISEPDVVEQPEEEEEEDGHGILDE LSAEEEDALESASAFTTACRSVKKKIGNVFQTFSVKNVSKQFKKIKKLSIKEIVAGFFSF FWMLFTGFFKGIYGLIFGFFHVIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDV IEGEKVEAIESSRSSDTAMAPAGDITEVDSMFEMLSNPKKEGGKHVEPGLGDISELTAEI STTDQKKKAAAKPVETPENEPEKADSENQEKEDKPKKEEEAKEPVAEEKPKARASPSKEA ASSFMLSIFAVLDIFLTKMLNFLARNFYNLRFLALFVCFAINFILLFYKVTGESEDEEVD EEDTWDGDEDNDGADTFFDMDEFVLQESTGYMLPTLRFLAVSHTVISLVCLFGYYCLKVP LVVFKREKEIARKLEFDGLYITEQPSDEDIKGQWDRLVINTPSFPSNYWDKFIKRKVINK YGDMYGAERIAELLGLDKSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKMGVVLTDNY FLYLIWYSVMSIFGHFNNFFFAAHMLDIAMTLKTLRTILSSVTHNGKQLVLTVGLLAVVV YLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDS YELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYF DRTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPTGDCF RKQYEDQLG NT seq 13890 nt NT seq  +upstreamnt  +downstreamnt atgcgtctttgtcatgggcatgatgagagcttgaccatccctggagcagaaaagagtgag gaggagcagaggatagtcaactatgaagcgggtaagggagcgtcaaaggcccgctcactt tggagactggagcctctgaggatcagctggagcggtagccacattcgcttgggtcaggcc ttccgactccgccacctcgctaccggccattacctggccatgactgaggatcgcggactg gtcctgcaggacagggagaagtccgacaccacggccactgcgttctgcttcaggccctcc aaggaaaagggcgactcaggcccaaagagggacattgaaggcatgggagtggcagagatc aagtacggagactctgtgtgcttcatcatgcatgtggcgtcgggactgtggttgtcctac ctggcgcctgatgccaaatcatctcgcctcggacccctgaaaagaagagcctgcctgcat tctgagggccacatggacgatggacttatcctgcagcgctgtcagcatgaggagtctcgg gctgctcgcatcatccgcaacagcacattcctcttcaccaactttataaaggctttggac agcattgcagagggggagtccacggcggtggccgattatgttgaagaggtgctgcagacg ctgaacgacctgatcgagtacttcaaacagcccgattccgagctggagcacgaggagaag cagtgtcttctccgttcactcatcaaacgtcaagacctcttcaaagatgagcgcatgctg gccctcctgtccaaatgcattgaccggatgaacctgtacaacagcgctgcccactttgga gaggtggctggggaggaggcaggctcggcgtggaaagacattctcaacctcctctatgaa cttttggccgcattgattcgtgggaacaggaacaactgcacccagttttcccgcaacttg gactggttggtcagcaaactggagagactggaatcttcatcagggatccttgaagtcctc cactgtatcctggtagaaagtccagaggctctgaacatcattcagaaaggtcacattaaa tccataatctctctgctctacaagaatggacgcaactacaagattctggatgtcctgtgt tccctctgtgtttgtaacggggtggcagtgagagccaatcagaatctgatctgtgacaac ctgcttcccaagagagacctgctgctccaaactcgactggtcaatgatgttcagagcatg aggccgaacatcttcctgggcgtagctgaaggttcagctcagtataagaagtggtatttt gagctggtgatcgaccaggtggaccactttgtcaccggagagccgacccacctgagggtc ggctgggccaacactgaaggctacgctccgtaccccggtggaggagaggggtggggtggc aatggtgctggggatgacctgtactcctacagctttgacggacttcatctctggtcaggc cgagtcccgagggccgtggcctccattaaccagcacctgctgaactcagacgacgtggtc agctgctgtctggatttgggcgctcccagcatgtccttccggatcaacgggcagcctgtc cagggcatgttcgaggacttcaacacggatgggttcttcttccccgttgtgagcttctct gcaggtgtcaaggcccgtttcctgttgggtggacgtcacggagatttcaagttcctgcca cccgctggttactctccatgctacgaggcgctgctgcccaaagagaagatgcacgtcgag cctgtgaaggactacaagagggaccatgatggcgtccgtgacctgctgggaaccaccaag ttcctcagtcaggcctccttcatccccactcctgttgacaccagccagattgttcttccc actcacctagacaacgtccgggacaagctggcagaaaacatccacgagctgtgggggatg aacaagatcgaactgggctggacctatggcaaggttcgcgatgacaacaagagacagcac ccctgccttgtggatttcggaaagctgcctgaaactgaaaggaactacaacgtgcagatg tctagtgaaacacttaagaccctgttggctcttgggtgccatgttgtccaggcgtatgtt aacgctgaggacgatctgaagaaaatcaaacttcccaaagactacatgatgtctaatgct tataagcctgcaccactggacctctctgacgtgaagctgactgcaggtcaggagtttcta gttgataaactggctgagaatgcgcacaatgtgtgggccaaagacagaattaaacaagga tggacctacggcatccagcaggatttgaagagcaggcgtaatcctcgcctggtgccgtac gctttactggacgagcgcactaagaaatctaacagagacagtctgagggaggccatccgg accatggtgggatacggttatgacatcgaccccccagaccaggaggccctccatgtgatg gatgatcagaacatcgacaccatccgcttcttccgtgtggagcagacgtacgcattgaag acagggaagtggtactttgagtttgaggctttgagtggaggcgatatgagggttggctgg gccagaccgggctgcaggcctgacgtggaactgggaacggatgaccaggcctttgtcttc gatggattccagggtcgtcgtatgcacgcaggtgcccgctactttggacaaccttggaaa aaaggcgacgtggttggatgcatgatcaacatggaggacaagtccatgatcttcaccctg aacggagaactcctgatcaccagcaagggctctgagctttgcttcactgactttgagacg gaggacggtttcatccctgtgtgcagtatggccatggctcaggtcggacatatgaacctg ggcaaggacgccagcacttttaagtactacaccatgtgtggtctccaggaaggctttgag cccttcggtgtcaacatgaacagagacatcaccatgtggttcagcaagcgccttcccacc tttgtcaacatacccaaagaccacatgcatatcgaggtgacaaggatcgacggaacggtg gacagccctccatgcctcaaggtcacacacaagacgttcggcacgcagaacagcaacagt gacatgacctactgcagactgagcatgcctgtggagttctactctgcagacaagatactg gacgaatcactgaaactcagccatcctccaaaagaagatggaactgttgactatggaagc atcacaacttactaccactcagtgagagtgtttgctggacaggaccctgcgtcagtgtgg gtgggctgggtcacaccggactatcattactacagcaagaacttcagcctcaacaagatg cggacagtcaccgtcaccctgggagacgagaggggccgtgtccatgagagtgtccagagg agcaactgctacatagtgtgtggagcggacgcagtcggcccgtcctcgtccagccgctcc aactctgacctggagatcggctgtctgattgacctcgccaccggcctcgtctccttcact gccaacggcaaagagctgtccacaacataccaggtggagccaaataccaagctgttccca gctgtgttcgtacgccccacgagtgcaaacctcttccagatggaatttgtgaagatcaag gatgccatgccgctctcgtctgccatatttaagagcgagcacaggaacccggtgcctcag tgtccgccgcgtctggatgtgcagaccatcatggccgtgctgtggagccggatgccgaac accttcctcaccgtggagaccgctcgagtcagcgagaggcacggctgggtggtccagtgt ctggagccgctggagatgatggccgtacatatacctgaggagaacagatgtctggacatc ctggagttatctgagcttgaagacctgagaaagttccactaccacacactgaagctgtac tgcgccctctgtgccctgggaaacacccgcgttgctcacgccctctgcagccacttggac caatcacagctgctctacaccatcgacaaccaattcctctccggcatgctgagagagggc ttctacaatgtcctcatcagcatccatcttgaaacggcaaaggaggctcgcctgatgatg aacaacgagttcatcatccctgtgacggacgagactcgttccatcaagctgttccccgat gagtccaagcggcactcgctgcctggcgtggacctgagcacctccctcaaacctcgggtc aacttctccgccgtcggcatcatcaacacgaagcgccagcagttcctctacagcccccag atccctctgggcagcctgaaggagaaagccatcagcatgctctctgaggccgtgcagggc ggaggcacacacatccgagacccggtaggcggcagcgtagagtaccagttcgtccccatc ctgaagctgatcggaacgctgttaatcatgggagtcctgaccagagaggaggtacgaatg attctcctcctgattgaccccaacgtgttcggagaggccaaggagggcgaggacgccaag ggggacgagggggtgtcgcgggagaaggaggaagtgagcaagaacgaggagaaggctgtg gaggcgggagaggaggagacgaaggagagcaaaccgctcattaaaggtctgctggagaag tccctgcccgagcccgtcaaacgccagatgtgcgagctgctgcactacttctgtgactgt gagctgaagcatcgcatcgagtccatcgtctccttctcagacagcttcgtgtccaagctg cagttcaaccagaagttccgctacaatgagctgatgctggcgttcaacatgtccgccgcc atcactgccaagaagaccaaagagtttcgttcaccgccacatgagcagatcaatatcctg ttgaatttcagtgcaggggaggactgcccctgtccggaggacatccaggatgagctaaac tctttccatgaagaattgcgactgcactgtggaattcccgtggaggaggaagaggaagag caggacacttcaataaaaggccgtctcctcgctttactctacaagatcaaaggtgcacct cataagaccgaagcagaacccacagagaaggaacaggctgctcccaccaacctgaaggag ctgatctctcagaccataaccagctgggctcaggagtctcacatccaggacccagagctg gtcagagtgatgttcagcctgctaaggaggcagtatgacggcatcggggagctgctccga gccatgaagaaatcctacaccatcagtgccgcctccgtacaggatgctattaacctgttg gtgtctctgggtcaaatccgctctctgctgtcagtacgcatgggcaaggaggaggagaaa ctcatgattgatggactaggcgacatcatgaacaacaaggttttctaccaacatcccaac ctgatgcgagtgctgggcatgcacgagaccgtcatggaggtcatggtgaacgtgctggga ggagataagttacaggagatcaccttccccaagatggtggccagctgttgtcgcttcttg tgctacttctgtcgtatcagccggcagaaccagaaagccatgtttgaccacctgagctac ctgctggagaacagcagtgtcgggctggcctctgaagctatgcggggctccactccgctg gatgttgcagcatcttcagtgatggacaacaacgggctgtctctggccctggaggagtct gatctggagaaggtggtgacatacctggcaggctgtggtcttcagagttgtgccatgctg cttgctaagggttacccagacctcggctggaaccctatagagggagagcgctacctgtcc ttcctgaggttcgtcgtcttctgcaacggtgagagtgtggaggaaaatgccaacgtggtg gtaaagctgctgatcagacgtccagagtgtttcggccccgccctgaggggagaggggggt cagggtttgcttgccgccatgaaggaggccatcaagatttcggataatcctgccctggac cttcccaagacggccgctggggtcaatactgggtccagtgaggaagaagaagaaattatt cacatgggcaacgccatcatgtccttctactcggctcttattgacctgctgggacgctgc gctccagagatgcatcttatcaatgcgggtaaaggcgaggcgctgcgtatccgagccatc ttgcgctctctggttcccacgatagacctggtgggaatcatcagcatccccctcagtttg cctgtgcttaataaagacggcaccgtgacagaacccgacatgtcagcctgtttctgtccg gaccacaaggcccccatggtgctcttcctagaacgagtgtacggcatcgaggaccagagc ttcctgctccagatgttggaggtcggcttcctacctgacctccgagcctccgcgtctctg gacacggaggtgttgagcaccacggagacggcgttggccatgaacaggtacatcggctcg gccctgctgcctctgctcacacgctgcgcggctctctttagcagcacggagcactacgca cagctgattgactccacgctgcagactgtctaccggctgtccaaaggacgctcactcacc aaagcccagagggacgccatcgaggagtgtctgctggctatctgcaagcacctgcgtccc tccatgatgcagcagcttcttagacggctggtgttcgacgttcccatgctcactgaatac tgccagatacctctccagcttctgaccaaccactatgatcaaaactggaagtactactgt ctgccttcggggatgatcagctgtggcatagcctccgaggaggagctcctcctgaccaag aagctcttctggggaatctttgactccctttctcagaagaagtatgacgcggaccttttc aaaatggccacgtcgtgcctgtgtgccatcgcaggagccatacctccagactttgtggac gccagtcttggagcaacactggagaaacaagcatccgtggatgcacagggcaactttgat cccaaacccatcaacactgccaatatctcccttcctgaaaaactcgagtacattgccaac aaatatgcagagcattcccacgacaaatggtcctccgagaaggtgtcagcaggctggaag catggagacagtctggatgatcaggccaaaacccacccactgctgaagctgtacaaagcg ctgagtgagaaggagagagaaacgtaccgctggccagttaaagagtcgctgaagagcatg ctggctatgggctggagcatcgagaggtccaaggaaggagacgccatgttccaacagcga gagagcgaaaaacaaaagctctccgatgctcagaacgatggattcactcctgctccaatg gatctgaacaacgtccctttgtctagagagttacagggcatggtggaggtggttgcagaa aactaccacaacatctggtccaagaagaagaaaactgaacttgttagcaaaggaggaggg acccacccgctgctggttccctatgacaccctgacggctaaagagaagtacagagacaga gagaaggcccaggagctcttcaagttccttcagatcagtggctatgccatcataagagat ctgaaggacatggagcaggactcctcgtccatggagaagcgtttttcctacaagttcctc aaaaggatgctgaagtacatcgactctgcccaggagttcatcgctcaccttgaggctatg gccaccagtgggaagacggacaagtcgcctcatgaccaggaaatcaagttctttgcgaag gtgttgcttcctctgacagatcaaacttttaagaatcactgtctctacttcctgtccaca cccagcaagggcctgagcagctgcggctgtgcgtccaacaaagagaaggagatggtcacc agcctgttctgtaagctggcagctcttgtcagacacaggatttctctctttggaagtgac tctgcaatgatggtgagctgtctgcacatcctcactcactcactcgacaccagaacggtg atgaagtctggctcggagctggtcaaagccgggtttcgggctttctttgagaatgcggcg gaggacctggagaagctgctggagatgctaaaactggggaagttcatgcagtcccgtgcg cagatgaagagcgtcacccaaagcatcaactacgtgaccgtggcgctgctgcccatcctc actgcgctgtttgagcacatcacgacatacgagtttggagtggacctgctgttgaacgat gtgcagctgtcctgttaccgaatcgtggccagtttctactgtctggggaccggaaagaac gtctttgtggagaggcatcttccagtgctgggggagagcctggcgaccctggtggcagcc atgcctgtggcgttcctggagccgcagctaaacactcacaacccgctgtctgtcttcaac accaagaccccccgagagagagccatcttgagtatgccggacacggtgttggagatgtgt ccggagatgcctcgtcttgaaggactgctgaaagacgtcagcgacgtgtcagagtctggt gctcgctacagcgacatgccacaggtcatcgaggtgatccttcccatgctgtgtaactac ctgtcctactggtgggacaaaggcccggagaactctcctccaggtgcccagtgctgcact atggtgacctctgaacacctcagcatcatcttggcaaacatcctgaagatcctcaacaac aacctgggcatcgatgacgccccctggatgaagaggattgcagtctactctcagccaatc atctgcaaggctgcagcagatctgctgagaacccacttcctgcccacactggaaaaattg aagaacaagacggtgaaggttgtgggtgaagaggagctgctgaaggccgacagtaaaggt gacacccaggaggccgagctgctcatcctggatgagtttgctgtgctctgcagagacctc tacgccttctaccccatgctcatccgttatgtggacaacaacaggtgccggtggctaaag gagccggacgcagactccacggagctcttcaggatggtggctgagatcttcatcctctgg tgcaagtcccacaactttaaacgtgaggagcaaaactttgtggttcagaatgagatcaac aatttgggcttcctgactggagagggcaaggcgaagatgtccaagtcagggggggaccag gagaggaaacacaagcgccgtcgaggcgagtactactccgtccagacctcgctgatcgta gccgccctgaagaagctgctgcccatcggcctcaacttgtgcagcccgggagaccaggag ctcatctccatcgccaagatacgctacagtctgaaagacacagatgacgaggtgaaggag catttgcgtcagaatttccacctccaggacaagtctgacgacccagcggtccagtggcag ctgaacctgtacaaggacgtagtgatgaagagcgaggaacctgcaaactcggaacacaca gtggaccgagtgcagagcatctcagctgcagtcttctacctggagcaggtggagcagcct ctgagaaataagaagtgtgttcggcagaagctgctgtctaaacaacgtaagcgtgctgtg gtggcttgtttccgcatggctccactctacaatctacccaggcatcgcgctatcaacttc ttcatcccggcctatcagagactttggatagaggcagaggagtactcctttgaggagaag ctagttcaggatctggcaaaaacccccatgaagattgtggaggaggaggaagaggaggtg gctgagatccagccggacccgctccaccaactcatcctccacttcagccacaacgccctg acggagagaagttacttggaagaggatccgttgtatattgcgtacgcggacatgatggca aagagctgtgcagaggacgaggaggaggaagaagaggaagaagggaaagaaaagactttt gaggaaaaagagatggagaagcagaagatcctgtatcagcaggcgaggctgcacgcgcgt ggagccgcagagatggtgctgcagatgatcagcgccagtaaaggtcgtctgggccccatg gtgacctgcaccctcaaactgggaatctccattttaaatggaggcaatgtgcaagttcag cagaaaatgctcgattacctgaaagagaaaagagatgccggctttttcaagagcctctca ggactgatgcagtcttgcagtgtcttggacttgaacgcatttgagaggcagaacaaagca gaaggtcttggcatggtgacagaagaaggttcaatcaacaatcagcggggttcgaaggtg ctacagaatgacgagtttactaaagatctcttccggtttttgcaacttctctgtgagggg cacaacggagatttccagaacttcctgagaacccaaacgggaaacacgaccacagtcaac atcattatcagcactgtggactacctgctccgtcttcaggagtccatcagcgacttctac tggtactactccggcaaagatgtcattgacgagaatggtaaagtcaacttctccaaagcg ttatctgttgccaagcagatcttcaactcgctgactgagtatattcagggcccgtgtatt gggaaccagcagagtttagctcacagcagactgtgggatgcagttgtgggcttcttgcat gtgtttgccaacatgcaaatgaagctttctcaggactccagtcagatcgagctgttgaag gagctgatggatttacagaaggacatgattgtcatgttgctgtctctgctcgagggtaac gtggtgaacggaacgattggaaagcagatggtcgacaccctggtggagtcttcgaacaac gtggagatgatcctcaagttcttcgacatgttccttaaactgaaggacctgacgtcctcg gacaccttcaaagcgaacgaccccgagttcaaaggcatcatttcaaagaaggagttccag aggtcaatggagaaccagatgcagtacagccagtctgaaatcgaattcctgctctcgtgt gcagacgccgacgagaacgacatgttcaattacaaggagtttgtggagcggttccacgag ccggccaaagatatcggcttcaacgtggcggtgctgctgaccaacctgtccgaacacatg ccacacgactccagactctccaccttcttagacctagcagagagcgtacttagctacttc gagccttatctgggtcgtattgaaatcatgggcagcgcgaagaggatcgagagggtgtac tttgagatcagcgagtcgagccgcgagcagtgggagaagccgcaggtcaaagagtccaag cgtcagttcatctttgacgtggtcaacgagggcaaggagagcgagaagatggagatgttt gtgaatttctgtgaggacaccatttttgagatgcagctggcctcgcagatctccgagcca gatgtggtggaacaacccgaggaggaggaagaggaagacggacacggcatcctggacgag ctgtctgcagaggaagaggacgccctggagtctgcctctgccttcacgaccgcatgccgc tcagtcaagaagaagatcgggaatgtcttccaaaccttttctgttaaaaacgtctccaag cagttcaagaaaatcaagaagctgagcatcaaggagatcgtcgccggcttcttctccttc ttctggatgctcttcaccggcttcttcaagggaatctacggcctcatcttcgggttcttc cacgtcatctggtcctccatgtttggcggtggcctggttgagggagccaagaacataaag gtgacggacatccttggaaacatgcccgacccaacccagttcggtatccacggagatgtg atcgaaggagagaaagtggaggccatagagtcgtcgcggagctcggatacagccatggca ccagcaggggacataacggaggtggactccatgtttgagatgctgtcgaatcccaagaag gaaggaggaaagcacgtggagccgggcctgggggatatttctgagctgactgcggagatc tccaccactgatcagaagaagaaagctgccgccaagcctgtcgaaacccccgagaacgaa ccggagaaagcagactcagagaaccaggagaaggaggacaagccgaagaaggaggaggag gccaaggagccggtggcggaggagaagcccaaggccagagcgagtccgtcgaaggaggcg gcgtcgtccttcatgttgagcatctttgctgttctggacatctttctgacgaagatgctg aacttcctggctcgtaacttctacaacctgcggttcctcgctctgtttgtgtgctttgcc atcaacttcattctcctgttctacaaggtcacgggtgaatctgaagatgaagaagtagac gaggaagacacctgggatggcgacgaggataacgacggtgcggacacattcttcgacatg gacgagtttgtcctgcaggagagcaccggctacatgttgccaacgctgcgcttcctggct gtatcccacacggtcatctcactcgtctgtcttttcggctactactgcctgaaggtgcct ttggtggtgttcaagagggagaaggagattgccaggaagcttgaattcgacggtctgtac atcaccgaacagccgtctgacgaagacatcaagggccagtgggatcgactcgtcatcaac acgccatctttcccgagcaactactgggacaagttcatcaagcgcaaggtgatcaacaaa tacggtgacatgtacggagccgaacgcatcgctgagctcttaggcctggataagagcgct ctggactttgaccccacagtggagacggtagagaaggaagcttctctgctctcctggctg agctccattgatacaaagtaccacatctggaaaatgggcgtagttctgactgacaattac ttcctgtatctgatctggtactccgtcatgtccattttcggacacttcaacaacttcttc tttgctgcccatatgctggacatcgccatgaccctcaagaccctccgcaccatcctgtct tctgtcactcacaacggcaagcagctcgtgctgactgtgggtctgctggccgtggtcgtc tatctctacaccgtcgtggccttcaacttcttcaggaagttctacaacaagagcgaggat gaggacgagcccgacatgaagtgtgacgacatgatgacgtgctatttgttccacatgtac gtgggcgtgagagctggaggtggtatcggagacgagttggaggacccagctggagactcc tatgagctctaccgcatcctgttcgacatcaccttcttcttctttgtcatcgtcatcctg ctggccatcattcagggtttgatcattgatgcctttggcgagctgagagaccagcaggag caggtgaaggaggacatggagactaaatgcttcatctgtggcattgggaatgactacttt gaccggacgcctcacgggttcgagacccacaccttacaagaacacaacctcgctaactac ctgttcttcctgatgtacctgattaacaaggatgagactgagcacacgggtcaggagtcg tacgtgtggaagatgtaccaggagagatgctgggacttcttccccactggagactgcttc cgtaagcagtacgaggaccagttgggttag

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